| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.130748 |
| ATP13A3 | ATPase type 13A3 | 0.128705 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0919502 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0890769 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0795395 |
| CADM1 | cell adhesion molecule 1 | 0.0749468 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0727996 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0695404 |
| STC1 | stanniocalcin 1 | 0.0664587 |
| ARRDC3 | arrestin domain containing 3 | 0.0650747 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.064217 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0588987 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0565694 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0554497 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0536472 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0531565 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0523203 |
| IL6ST | interleukin 6 signal transducer | 0.0519487 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0515529 |
| GOLGA4 | golgin A4 | 0.0514983 |
| RPS2 | ribosomal protein S2 | 0.0507621 |
| ADM | adrenomedullin | 0.0504957 |
| PDE10A | phosphodiesterase 10A | 0.0493624 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0490674 |
| PTK2 | protein tyrosine kinase 2 | 0.0489046 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0487523 |
| RPS6 | ribosomal protein S6 | 0.0485625 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.047995 |
| ENO1 | enolase 1, (alpha) | 0.0464743 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0444793 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0441631 |
| MRTFA | myocardin related transcription factor A | 0.0421878 |
| RASA2 | RAS p21 protein activator 2 | 0.0420213 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0419652 |
| HIP1 | huntingtin interacting protein 1 | 0.0418009 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0416899 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0405656 |
| LOXL2 | lysyl oxidase-like 2 | 0.0396429 |
| NDRG1 | N-myc downstream regulated 1 | 0.0383419 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0374067 |
| ZNF292 | zinc finger protein 292 | 0.0369171 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0364022 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0361862 |
| B2M | beta-2-microglobulin | 0.036181 |
| FMNL2 | formin-like 2 | 0.0355032 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0346033 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.034309 |
| TMF1 | TATA element modulatory factor 1 | 0.0340202 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0339092 |
| PDE8A | phosphodiesterase 8A | 0.0336618 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0332393 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0331878 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0330626 |
| RPS12 | ribosomal protein S12 | 0.0323665 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0323383 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0317052 |
| BBX | bobby sox homolog (Drosophila) | 0.0316464 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.03156 |
| MTSS1 | metastasis suppressor 1 | 0.0315585 |
| MED13L | mediator complex subunit 13-like | 0.031331 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.030218 |
| RPL37A | ribosomal protein L37a | 0.0301864 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0299798 |
| HAS2 | hyaluronan synthase 2 | 0.0296429 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0296401 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.029619 |
| IER3 | immediate early response 3 | 0.0295 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0294764 |
| YEATS2 | YEATS domain containing 2 | 0.028926 |
| RNF145 | ring finger protein 145 | 0.0289071 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0285762 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0284509 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0283142 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0282594 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0282379 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0277774 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0276707 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0275824 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0272315 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0272256 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0270511 |
| SPAG9 | sperm associated antigen 9 | 0.0269938 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.026693 |
| OGA | O-GlcNAcase | 0.0266482 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0264937 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0264291 |
| RPS8 | ribosomal protein S8 | 0.0263572 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0262578 |
| NCKAP1 | NCK-associated protein 1 | 0.0261289 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0260802 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0254158 |
| RAB10 | RAB10, member RAS oncogene family | 0.0250835 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0250235 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0247184 |
| CLIC4 | chloride intracellular channel 4 | 0.0245939 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0241543 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0238385 |
| TFG | TRK-fused gene | 0.0238312 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0237999 |
| TPR | translocated promoter region, nuclear basket protein | 0.0237022 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.345146 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.212824 |
| MT2A | metallothionein 2A | -0.211825 |
| FN1 | fibronectin 1 | -0.150241 |
| TMSB10 | thymosin beta 10 | -0.127532 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124632 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0848393 |
| MT1X | metallothionein 1X | -0.0838122 |
| FBN1 | fibrillin 1 | -0.0787653 |
| COL5A1 | collagen, type V, alpha 1 | -0.0767307 |
| FTL | ferritin, light polypeptide | -0.0689085 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0685859 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0647467 |
| GLIS3 | GLIS family zinc finger 3 | -0.0500637 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0454278 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0448521 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0446884 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0440302 |
| RRBP1 | ribosome binding protein 1 | -0.0435646 |
| PLEC | plectin | -0.0403198 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0393139 |
| PFN1 | profilin 1 | -0.038981 |
| EGR1 | early growth response 1 | -0.0382455 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0379092 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0373589 |
| HMGA2 | high mobility group AT-hook 2 | -0.0368909 |
| YBX1 | Y box binding protein 1 | -0.0366969 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0366361 |
| HDLBP | high density lipoprotein binding protein | -0.0363596 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0361653 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0358741 |
| VIM | vimentin | -0.0351533 |
| RPS19 | ribosomal protein S19 | -0.0348654 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0341792 |
| COL1A1 | collagen, type I, alpha 1 | -0.0338679 |
| CANX | calnexin | -0.0320827 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0307664 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0304999 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303415 |
| TMEM263 | transmembrane protein 263 | -0.0298074 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0289698 |
| TAPBP | TAP binding protein (tapasin) | -0.0286396 |
| LDHA | lactate dehydrogenase A | -0.0286278 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0286062 |
| NABP1 | nucleic acid binding protein 1 | -0.0274406 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0262861 |
| LMNA | lamin A/C | -0.0255137 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.025469 |
| RPLP1 | ribosomal protein, large, P1 | -0.0254168 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0252232 |
| EHD2 | EH-domain containing 2 | -0.0249264 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0248406 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0248247 |
| AHNAK | AHNAK nucleoprotein | -0.0246388 |
| BSG | basigin (Ok blood group) | -0.024526 |
| H1-0 | H1.0 linker histone | -0.0244664 |
| CNTN5 | contactin 5 | -0.024242 |
| WASF2 | WAS protein family, member 2 | -0.0241076 |
| DGKI | diacylglycerol kinase, iota | -0.0239388 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0238474 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238329 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0237577 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0231875 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0231408 |
| ARF1 | ADP-ribosylation factor 1 | -0.0231075 |
| PXDN | peroxidasin | -0.0231002 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0230903 |
| MAP1B | microtubule-associated protein 1B | -0.0221647 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0221476 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0219653 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0219265 |
| GANAB | glucosidase, alpha; neutral AB | -0.0212235 |
| CCND1 | cyclin D1 | -0.0211229 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0207588 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0205637 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0205274 |
| NEK10 | NIMA-related kinase 10 | -0.020329 |
| RPL32 | ribosomal protein L32 | -0.0202057 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0200959 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0200675 |
| INTS6 | integrator complex subunit 6 | -0.0199878 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0195959 |
| RPL28 | ribosomal protein L28 | -0.0194977 |
| FLNA | filamin A, alpha | -0.0194485 |
| NAV3 | neuron navigator 3 | -0.0191837 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0191503 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0190169 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0189905 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0188845 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0186027 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0180768 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.0178801 |
| PRSS23 | protease, serine, 23 | -0.0176432 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.017634 |
| HMCN1 | hemicentin 1 | -0.0175981 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.01756 |
| RASAL2 | RAS protein activator like 2 | -0.0175322 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0175131 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0174971 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0174739 |
