| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.137519 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0931844 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0821489 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0805641 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0715959 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0704233 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0610367 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0576226 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0554493 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.048519 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0474693 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0443029 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0437042 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0404149 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0387605 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0380431 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0373803 |
| DTNA | dystrobrevin, alpha | 0.0367149 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0366154 |
| CDK19 | cyclin-dependent kinase 19 | 0.0359906 |
| AHR | aryl hydrocarbon receptor | 0.0353624 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0353428 |
| FAT1 | FAT atypical cadherin 1 | 0.0343044 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0343016 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0339053 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0331552 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0331509 |
| FMNL2 | formin-like 2 | 0.0327419 |
| KRT8 | keratin 8, type II | 0.0325751 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0319711 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0318245 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0317222 |
| ZNF292 | zinc finger protein 292 | 0.0310862 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.03108 |
| KIF1B | kinesin family member 1B | 0.0307942 |
| PLIN2 | perilipin 2 | 0.0306759 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0298558 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0290402 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0288625 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0274665 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0268916 |
| SMAD4 | SMAD family member 4 | 0.0265668 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0260769 |
| POTEF | POTE ankyrin domain family, member F | 0.0259912 |
| SBF2 | SET binding factor 2 | 0.0257711 |
| APOA2 | apolipoprotein A-II | 0.0256628 |
| RTN4 | reticulon 4 | 0.02561 |
| KIAA1217 | KIAA1217 | 0.0254684 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0254459 |
| PTCHD4 | patched domain containing 4 | 0.0245042 |
| ATP13A3 | ATPase type 13A3 | 0.0243632 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0243176 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0241886 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0241559 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0241426 |
| FOXO1 | forkhead box O1 | 0.0236366 |
| THOC2 | THO complex 2 | 0.023543 |
| DST | dystonin | 0.0232938 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0229761 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.022898 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0226313 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.0224811 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0221402 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0218492 |
| PRELID2 | PRELI domain containing 2 | 0.0218321 |
| RNF149 | ring finger protein 149 | 0.0217915 |
| RPL3 | ribosomal protein L3 | 0.0214273 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0213757 |
| VCL | vinculin | 0.0212516 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.021238 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0212096 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0211958 |
| YAP1 | Yes-associated protein 1 | 0.0211538 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0211511 |
| LRRC1 | leucine rich repeat containing 1 | 0.0210303 |
| FNIP1 | folliculin interacting protein 1 | 0.0209183 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0208613 |
| HELZ | helicase with zinc finger | 0.0207844 |
| METTL15 | methyltransferase like 15 | 0.0206498 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0206308 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0205354 |
| MYO1B | myosin IB | 0.020302 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0202216 |
| USP3 | ubiquitin specific peptidase 3 | 0.0200434 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.019857 |
| CHKA | choline kinase alpha | 0.0198448 |
| NCKAP1 | NCK-associated protein 1 | 0.019766 |
| FRK | fyn-related Src family tyrosine kinase | 0.0195287 |
| CRLS1 | cardiolipin synthase 1 | 0.0194211 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0187522 |
| DIAPH3 | diaphanous-related formin 3 | 0.0183957 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0181071 |
| GOLGA4 | golgin A4 | 0.0180711 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0180378 |
| PFN1 | profilin 1 | 0.0179793 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0179784 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0178804 |
| CLIC4 | chloride intracellular channel 4 | 0.0177616 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0176808 |
| HMGA1 | high mobility group AT-hook 1 | 0.0176047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.195487 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.177437 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.176383 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.114507 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0821406 |
| GPC6 | glypican 6 | -0.0816503 |
| RPLP1 | ribosomal protein, large, P1 | -0.0748256 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0726282 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0687057 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0652501 |
| RPS24 | ribosomal protein S24 | -0.0646427 |
| C3 | complement component 3 | -0.0620806 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0614777 |
| RBM39 | RNA binding motif protein 39 | -0.0613541 |
| RPLP0 | ribosomal protein, large, P0 | -0.060247 |
| SMAD3 | SMAD family member 3 | -0.0588051 |
| CP | ceruloplasmin (ferroxidase) | -0.0577235 |
| RRBP1 | ribosome binding protein 1 | -0.0537794 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.052405 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0521064 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0512519 |
| GPC3 | glypican 3 | -0.0506059 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0500649 |
| RPS6 | ribosomal protein S6 | -0.0497105 |
| PEG3 | paternally expressed 3 | -0.0494981 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0474987 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.047211 |
| FTL | ferritin, light polypeptide | -0.0467107 |
| CANX | calnexin | -0.0449243 |
| RPS19 | ribosomal protein S19 | -0.0439504 |
| EHBP1 | EH domain binding protein 1 | -0.043917 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0433279 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0428727 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0423683 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0418747 |
| RPL38 | ribosomal protein L38 | -0.0416754 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0416258 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.041607 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0415315 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0406015 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0405743 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0405339 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0399873 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0398686 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0396761 |
| RPL37A | ribosomal protein L37a | -0.0385229 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0383752 |
| HDLBP | high density lipoprotein binding protein | -0.0379733 |
| FOXP1 | forkhead box P1 | -0.0378403 |
| NINL | ninein-like | -0.0376214 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0369394 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0362884 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0362647 |
| FUS | FUS RNA binding protein | -0.0361001 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0358836 |
| PERP | PERP, TP53 apoptosis effector | -0.0352945 |
| RPL37 | ribosomal protein L37 | -0.0352191 |
| RPS8 | ribosomal protein S8 | -0.0349294 |
| RPS27A | ribosomal protein S27a | -0.0347977 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0346385 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0344223 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0343331 |
| GK | glycerol kinase | -0.0339822 |
| SQSTM1 | sequestosome 1 | -0.0339384 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.033551 |
| ZFHX3 | zinc finger homeobox 3 | -0.033302 |
| LCN2 | lipocalin 2 | -0.0332545 |
| INSR | insulin receptor | -0.0331273 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0329826 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0328807 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0327412 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0326903 |
| EGR1 | early growth response 1 | -0.0320365 |
| MT2A | metallothionein 2A | -0.0319388 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0319047 |
| A2M | alpha-2-macroglobulin | -0.0319034 |
| RAI14 | retinoic acid induced 14 | -0.0318946 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0316667 |
| FAM107B | family with sequence similarity 107, member B | -0.0314501 |
| HM13 | histocompatibility (minor) 13 | -0.0313922 |
| IER3 | immediate early response 3 | -0.0313624 |
| TFRC | transferrin receptor | -0.0313327 |
| TRIM26 | tripartite motif containing 26 | -0.0311774 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0309149 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0307335 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0305716 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0305644 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0303737 |
| RPL13A | ribosomal protein L13a | -0.0303252 |
| CTSB | cathepsin B | -0.030301 |
| TXNRD1 | thioredoxin reductase 1 | -0.0302514 |
| TULP4 | tubby like protein 4 | -0.0301488 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0295929 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0294113 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0293451 |
| SKI | SKI proto-oncogene | -0.0292179 |
| RPL34 | ribosomal protein L34 | -0.028211 |
| RPL35A | ribosomal protein L35a | -0.0281743 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0275955 |
