| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.118518 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0900834 |
| ANLN | anillin, actin binding protein | 0.0869235 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0802404 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0778501 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0755596 |
| TES | testin LIM domain protein | 0.0731372 |
| EMP1 | epithelial membrane protein 1 | 0.0713746 |
| AREG | amphiregulin | 0.068714 |
| RPS6 | ribosomal protein S6 | 0.0616703 |
| ZNF292 | zinc finger protein 292 | 0.0611953 |
| ATXN1 | ataxin 1 | 0.0605488 |
| OGA | O-GlcNAcase | 0.058106 |
| GOLGA4 | golgin A4 | 0.0579008 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0576869 |
| SPAG9 | sperm associated antigen 9 | 0.0561478 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0539491 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0532057 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0519456 |
| RPS3 | ribosomal protein S3 | 0.0516407 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0510876 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0501432 |
| RBM39 | RNA binding motif protein 39 | 0.0495174 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0490804 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0489386 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0488678 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0471707 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0465598 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0465424 |
| TPD52 | tumor protein D52 | 0.0461039 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0457873 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0457006 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.04519 |
| FAM13A | family with sequence similarity 13, member A | 0.0450747 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0450142 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0449754 |
| PREPL | prolyl endopeptidase-like | 0.0441247 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0436932 |
| COG5 | component of oligomeric golgi complex 5 | 0.0436545 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0430048 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0427419 |
| ITGA6 | integrin, alpha 6 | 0.0427079 |
| TPX2 | TPX2, microtubule-associated | 0.0423782 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0422208 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0420328 |
| KLHL29 | kelch-like family member 29 | 0.0416383 |
| DIAPH3 | diaphanous-related formin 3 | 0.0413303 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0411867 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0407655 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0404463 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0404112 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0403777 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.039821 |
| YEATS2 | YEATS domain containing 2 | 0.039009 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0390048 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0376423 |
| HKDC1 | hexokinase domain containing 1 | 0.0367471 |
| NDRG1 | N-myc downstream regulated 1 | 0.0363072 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0361535 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0360894 |
| HELZ | helicase with zinc finger | 0.0359556 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.035555 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0354842 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0354016 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0353822 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0352012 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0350268 |
| S100P | S100 calcium binding protein P | 0.0347343 |
| PRELID2 | PRELI domain containing 2 | 0.0345741 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0345383 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0344753 |
| RLF | rearranged L-myc fusion | 0.0344531 |
| TOP1 | topoisomerase (DNA) I | 0.0343423 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0341042 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.034052 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0333856 |
| AHNAK | AHNAK nucleoprotein | 0.033043 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0329299 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0328912 |
| RPL37A | ribosomal protein L37a | 0.032637 |
| FNIP1 | folliculin interacting protein 1 | 0.0319381 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0318763 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0316261 |
| RPL18 | ribosomal protein L18 | 0.0315592 |
| MORF4L2 | mortality factor 4 like 2 | 0.0314744 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0313789 |
| TMF1 | TATA element modulatory factor 1 | 0.0310167 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0310067 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0309935 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0308119 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0307907 |
| CDK19 | cyclin-dependent kinase 19 | 0.0307459 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0305108 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0304841 |
| XPO1 | exportin 1 | 0.0303093 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0302448 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0302105 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0300253 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0296728 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0296516 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.149737 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.141194 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.119198 |
| LMO7 | LIM domain 7 | -0.103958 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.101403 |
| TMC5 | transmembrane channel-like 5 | -0.0945825 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0945049 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.083315 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0795834 |
| RNF213 | ring finger protein 213 | -0.0761512 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0745508 |
| FAT1 | FAT atypical cadherin 1 | -0.0744938 |
| PLSCR1 | phospholipid scramblase 1 | -0.0660703 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0638354 |
| HLA-A | major histocompatibility complex, class I, A | -0.0626094 |
| CDK6 | cyclin-dependent kinase 6 | -0.0605854 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0586018 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0550235 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.054974 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0541915 |
| PRSS3 | protease, serine, 3 | -0.0521399 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0510156 |
| S100A6 | S100 calcium binding protein A6 | -0.0502183 |
| ASPH | aspartate beta-hydroxylase | -0.0497704 |
| POTEF | POTE ankyrin domain family, member F | -0.0495327 |
| SP100 | SP100 nuclear antigen | -0.0491017 |
| AOPEP | aminopeptidase O (putative) | -0.0470325 |
| TMEM45B | transmembrane protein 45B | -0.0469267 |
| ETV6 | ets variant 6 | -0.0466542 |
| MUC17 | mucin 17, cell surface associated | -0.046183 |
| MCU | mitochondrial calcium uniporter | -0.0459509 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0452151 |
| CALR | calreticulin | -0.0435181 |
| TMSB10 | thymosin beta 10 | -0.0434879 |
| WWC1 | WW and C2 domain containing 1 | -0.0424663 |
| HLA-E | major histocompatibility complex, class I, E | -0.0419676 |
| ATF5 | activating transcription factor 5 | -0.0412434 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0411343 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0401612 |
| TXNRD1 | thioredoxin reductase 1 | -0.0401509 |
| SEPTIN9 | septin 9 | -0.0399616 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0393509 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0386145 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0383006 |
| PKM | pyruvate kinase, muscle | -0.0380616 |
| FOXP1 | forkhead box P1 | -0.0375073 |
| ITGB4 | integrin, beta 4 | -0.0368093 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0350106 |
| B2M | beta-2-microglobulin | -0.0346764 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0346497 |
| CUX1 | cut-like homeobox 1 | -0.0346058 |
| ATP11A | ATPase, class VI, type 11A | -0.0343732 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0342838 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0340029 |
| MYO1E | myosin IE | -0.0338434 |
| MUC13 | mucin 13, cell surface associated | -0.0328133 |
| RRBP1 | ribosome binding protein 1 | -0.0327956 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0325313 |
| MX1 | MX dynamin-like GTPase 1 | -0.0321215 |
| TAPBP | TAP binding protein (tapasin) | -0.032035 |
| MX2 | MX dynamin-like GTPase 2 | -0.0319362 |
| KRT18 | keratin 18, type I | -0.0317251 |
| TTYH3 | tweety family member 3 | -0.0316103 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0314266 |
| PHF14 | PHD finger protein 14 | -0.0312181 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.031164 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0310706 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0309769 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308575 |
| ATM | ATM serine/threonine kinase | -0.0305384 |
| LCN2 | lipocalin 2 | -0.0304874 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0302579 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0302508 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0301519 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0301013 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0297087 |
| RIGI | RNA sensor RIG-I | -0.0292718 |
| MGAM2 | maltase-glucoamylase 2 (putative) | -0.0292058 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0287346 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0286781 |
| RUNX1 | runt-related transcription factor 1 | -0.0284966 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0284886 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028221 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0282156 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0279573 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0278653 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0277913 |
| PRKCA | protein kinase C, alpha | -0.0274746 |
| EFNA5 | ephrin-A5 | -0.0271823 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0270167 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0265745 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0263065 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0261315 |
| VEGFA | vascular endothelial growth factor A | -0.0259417 |
| MYO1D | myosin ID | -0.0259259 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0254464 |
| EPCAM | epithelial cell adhesion molecule | -0.0254236 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.025408 |
| ADAR | adenosine deaminase, RNA-specific | -0.0252524 |
| YAP1 | Yes-associated protein 1 | -0.0252034 |
