| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0998613 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0789714 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0787535 |
| SET | SET nuclear proto-oncogene | 0.0756641 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0722979 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0719595 |
| RPS12 | ribosomal protein S12 | 0.0716447 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0708611 |
| EREG | epiregulin | 0.0649104 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0628133 |
| RPS2 | ribosomal protein S2 | 0.0594574 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.058412 |
| SLK | STE20-like kinase | 0.0571051 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0566233 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0543463 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0529316 |
| OGA | O-GlcNAcase | 0.0486349 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.048277 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0463234 |
| DST | dystonin | 0.0457189 |
| XPO1 | exportin 1 | 0.0454519 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0447122 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0442681 |
| GOLGA4 | golgin A4 | 0.0429412 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.042855 |
| YEATS2 | YEATS domain containing 2 | 0.0422615 |
| RPL37A | ribosomal protein L37a | 0.0416137 |
| WDR43 | WD repeat domain 43 | 0.041257 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0395751 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0394091 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0384564 |
| SLC38A2 | solute carrier family 38, member 2 | 0.038108 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0377226 |
| ARRDC3 | arrestin domain containing 3 | 0.0375151 |
| FMNL2 | formin-like 2 | 0.0369324 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0369269 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0368349 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0368057 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0363886 |
| ZNF292 | zinc finger protein 292 | 0.0361125 |
| RAI1 | retinoic acid induced 1 | 0.0360863 |
| HDGF | hepatoma-derived growth factor | 0.0355421 |
| F2R | coagulation factor II (thrombin) receptor | 0.0355411 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0354333 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0349132 |
| JMJD1C | jumonji domain containing 1C | 0.034489 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0344074 |
| CAPRIN2 | caprin family member 2 | 0.0342434 |
| SBF2 | SET binding factor 2 | 0.0342367 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0342209 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.034121 |
| ZNF148 | zinc finger protein 148 | 0.0335115 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0333161 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.032974 |
| PGK1 | phosphoglycerate kinase 1 | 0.0324193 |
| RPS6 | ribosomal protein S6 | 0.031679 |
| PLK2 | polo-like kinase 2 | 0.0315925 |
| KIAA1958 | KIAA1958 | 0.0313891 |
| CDK19 | cyclin-dependent kinase 19 | 0.0311908 |
| NUP58 | nucleoporin 58 | 0.0311026 |
| FAM13B | family with sequence similarity 13, member B | 0.0308172 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0306485 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.030507 |
| PDE8A | phosphodiesterase 8A | 0.0305051 |
| TPR | translocated promoter region, nuclear basket protein | 0.0303692 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0302663 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.030125 |
| SQSTM1 | sequestosome 1 | 0.0300131 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0298254 |
| FOXJ3 | forkhead box J3 | 0.029805 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0294464 |
| TXNIP | thioredoxin interacting protein | 0.0291893 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0287483 |
| TPM3 | tropomyosin 3 | 0.0287183 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0279838 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0279486 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0276586 |
| SETD5 | SET domain containing 5 | 0.027626 |
| NGLY1 | N-glycanase 1 | 0.0274735 |
| MKI67 | marker of proliferation Ki-67 | 0.0271314 |
| HELZ | helicase with zinc finger | 0.0269205 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0266196 |
| OPTN | optineurin | 0.0264457 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0264336 |
| SEC24A | SEC24 family member A | 0.0262666 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0261325 |
| RNF145 | ring finger protein 145 | 0.026051 |
| CEP170 | centrosomal protein 170kDa | 0.0258955 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0258648 |
| MYOF | myoferlin | 0.0258452 |
| RASAL2 | RAS protein activator like 2 | 0.025813 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0257851 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0257779 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0257279 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0257115 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0256412 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0256338 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0256294 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0252439 |
| SEPTIN7 | septin 7 | 0.0252369 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.306832 |
| TMSB10 | thymosin beta 10 | -0.181499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.162242 |
| MT2A | metallothionein 2A | -0.130956 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.108042 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0978178 |
| TP63 | tumor protein p63 | -0.087569 |
| FTL | ferritin, light polypeptide | -0.0847068 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0836297 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733392 |
| RPL35A | ribosomal protein L35a | -0.0701096 |
| MT1X | metallothionein 1X | -0.0692569 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.063235 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0604629 |
| HDLBP | high density lipoprotein binding protein | -0.0568532 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0567566 |
| CANX | calnexin | -0.0553801 |
| APP | amyloid beta (A4) precursor protein | -0.0547203 |
| EGR1 | early growth response 1 | -0.0546676 |
| RPS24 | ribosomal protein S24 | -0.0534507 |
| CADM2 | cell adhesion molecule 2 | -0.0507496 |
| TNS3 | tensin 3 | -0.0460665 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0459374 |
| AHNAK | AHNAK nucleoprotein | -0.0458004 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0456524 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0453235 |
| CMIP | c-Maf inducing protein | -0.044249 |
| YBX1 | Y box binding protein 1 | -0.043558 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0420649 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0410289 |
| H1-0 | H1.0 linker histone | -0.0402537 |
| SP100 | SP100 nuclear antigen | -0.0396756 |
| HMGA1 | high mobility group AT-hook 1 | -0.0393029 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0390912 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0387981 |
| RNF213 | ring finger protein 213 | -0.0382433 |
| LDHA | lactate dehydrogenase A | -0.0377725 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0376108 |
| RPLP1 | ribosomal protein, large, P1 | -0.0374483 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0362714 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0349708 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0346917 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0346093 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.034522 |
| INTS6 | integrator complex subunit 6 | -0.0344543 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0335974 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0332434 |
| CALR | calreticulin | -0.0327379 |
| BSG | basigin (Ok blood group) | -0.0325643 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0310112 |
| VIM | vimentin | -0.0309357 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.030123 |
| ARF1 | ADP-ribosylation factor 1 | -0.0300874 |
| PLSCR1 | phospholipid scramblase 1 | -0.0299707 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0297907 |
| RPLP0 | ribosomal protein, large, P0 | -0.0295352 |
| FUS | FUS RNA binding protein | -0.0295161 |
| RPS19 | ribosomal protein S19 | -0.0294549 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.029179 |
| HLA-B | major histocompatibility complex, class I, B | -0.0290899 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0287024 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0281895 |
| TMSB4X | thymosin beta 4, X-linked | -0.0280668 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0276235 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0264347 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0262591 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0262269 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.026152 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0256782 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0256377 |
| OSMR | oncostatin M receptor | -0.0255753 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0255227 |
| GNAS | GNAS complex locus | -0.0254151 |
| SKP1 | S-phase kinase-associated protein 1 | -0.025159 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0250825 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0250655 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0247079 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0245575 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0244523 |
| TFRC | transferrin receptor | -0.0244081 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0243316 |
| ZNF217 | zinc finger protein 217 | -0.0243129 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0241997 |
| RPS4X | ribosomal protein S4, X-linked | -0.0240634 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0239271 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0238915 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0238551 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0237736 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0237515 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0236486 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0235208 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.023166 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0231378 |
| HMGB1 | high mobility group box 1 | -0.0230079 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0227668 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0226292 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0225233 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0224498 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0223892 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0223606 |
