| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.151089 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.107315 |
| ATP13A3 | ATPase type 13A3 | 0.0974676 |
| FAM13A | family with sequence similarity 13, member A | 0.0804666 |
| MEF2A | myocyte enhancer factor 2A | 0.0679239 |
| OGA | O-GlcNAcase | 0.0655612 |
| NGLY1 | N-glycanase 1 | 0.0650828 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0642115 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0620155 |
| SPAG9 | sperm associated antigen 9 | 0.0617005 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0580668 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0569764 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.055361 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0528304 |
| HELZ | helicase with zinc finger | 0.0524394 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0513454 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0512204 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0509707 |
| GOLGA4 | golgin A4 | 0.0507764 |
| USP3 | ubiquitin specific peptidase 3 | 0.050203 |
| FN1 | fibronectin 1 | 0.048852 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0488457 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0474225 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.047093 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0470796 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0461041 |
| PARD3 | par-3 family cell polarity regulator | 0.0457404 |
| USP34 | ubiquitin specific peptidase 34 | 0.0451892 |
| MYO1B | myosin IB | 0.0451389 |
| YEATS2 | YEATS domain containing 2 | 0.0450379 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0446812 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0444384 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0440487 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0433839 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0433036 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.042467 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0417455 |
| ZNF292 | zinc finger protein 292 | 0.040472 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0401861 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0385602 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0384318 |
| FMNL2 | formin-like 2 | 0.0382338 |
| RUNX1 | runt-related transcription factor 1 | 0.0381998 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0381273 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0365646 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0363713 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0363298 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0361556 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0353593 |
| SRP54 | signal recognition particle 54kDa | 0.0353057 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0352865 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0350643 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0349819 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0349594 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0349083 |
| FLNB | filamin B, beta | 0.034577 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0344634 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0342957 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0338977 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0337522 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0337093 |
| SMAD4 | SMAD family member 4 | 0.0315404 |
| CDC73 | cell division cycle 73 | 0.0302573 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0300899 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0292307 |
| CTNNBL1 | catenin, beta like 1 | 0.0291498 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0290084 |
| DENND4A | DENN/MADD domain containing 4A | 0.0289048 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.028898 |
| NPC1 | Niemann-Pick disease, type C1 | 0.028818 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0286379 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0284816 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0284408 |
| CERT1 | ceramide transporter 1 | 0.0283563 |
| INSIG2 | insulin induced gene 2 | 0.0282216 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0282112 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0281401 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0280186 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0279667 |
| CD109 | CD109 molecule | 0.0276056 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0274748 |
| ADD3 | adducin 3 (gamma) | 0.0274466 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0270079 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0270074 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.026891 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0268219 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0266238 |
| TBC1D15 | TBC1 domain family, member 15 | 0.026476 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0264279 |
| WDR45B | WD repeat domain 45B | 0.0263905 |
| SETD5 | SET domain containing 5 | 0.0262019 |
| YME1L1 | YME1-like 1 ATPase | 0.026028 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0258128 |
| RNF149 | ring finger protein 149 | 0.0257076 |
| RNF145 | ring finger protein 145 | 0.0255513 |
| CCNY | cyclin Y | 0.0253708 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0252777 |
| FOXJ3 | forkhead box J3 | 0.0251762 |
| RAI14 | retinoic acid induced 14 | 0.0248182 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0247965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174669 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.158929 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.15168 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.124507 |
| FTL | ferritin, light polypeptide | -0.106638 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0979679 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0833977 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0804075 |
| PCBP2 | poly(rC) binding protein 2 | -0.0735075 |
| ASPH | aspartate beta-hydroxylase | -0.066038 |
| MT2A | metallothionein 2A | -0.0637242 |
| PTMA | prothymosin, alpha | -0.060234 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0588504 |
| GLCCI1 | glucocorticoid induced 1 | -0.0578902 |
| VIM | vimentin | -0.0567377 |
| HDLBP | high density lipoprotein binding protein | -0.056224 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0553162 |
| NRG1 | neuregulin 1 | -0.0527248 |
| TMSB10 | thymosin beta 10 | -0.0512209 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0477532 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0449253 |
| RPS19 | ribosomal protein S19 | -0.0437934 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0436355 |
| LDHA | lactate dehydrogenase A | -0.0435999 |
| YBX1 | Y box binding protein 1 | -0.0414286 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0413772 |
| RPS24 | ribosomal protein S24 | -0.0409826 |
| EFNA5 | ephrin-A5 | -0.0408692 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.040773 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402922 |
| CANX | calnexin | -0.0387643 |
| RAD51B | RAD51 paralog B | -0.037526 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0373685 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0360799 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0354933 |
| HMGA1 | high mobility group AT-hook 1 | -0.0351107 |
| EGR1 | early growth response 1 | -0.0350846 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0347826 |
| RPLP0 | ribosomal protein, large, P0 | -0.0342889 |
| STC1 | stanniocalcin 1 | -0.0340422 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0335636 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0331101 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0324505 |
| GRAMD1B | GRAM domain containing 1B | -0.0318406 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0314469 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0312388 |
| FAM20C | family with sequence similarity 20, member C | -0.0310489 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0307862 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0301125 |
| FBN1 | fibrillin 1 | -0.0300541 |
| RPS6 | ribosomal protein S6 | -0.0296639 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0290324 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0287073 |
| NTN4 | netrin 4 | -0.0283514 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0280439 |
| H1-0 | H1.0 linker histone | -0.0277612 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0276604 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.027205 |
| YBX3 | Y box binding protein 3 | -0.0270492 |
| B2M | beta-2-microglobulin | -0.0268856 |
| NDRG1 | N-myc downstream regulated 1 | -0.0267865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0266594 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0265977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0265399 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0265348 |
| R3HDM2 | R3H domain containing 2 | -0.0265146 |
| KYNU | kynureninase | -0.0264722 |
| INTS6 | integrator complex subunit 6 | -0.026268 |
| ATXN1 | ataxin 1 | -0.0260362 |
| RPL11 | ribosomal protein L11 | -0.0259511 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0258732 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0249221 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0247815 |
| EXT1 | exostosin glycosyltransferase 1 | -0.024764 |
| VEGFA | vascular endothelial growth factor A | -0.0246137 |
| RPL19 | ribosomal protein L19 | -0.0245107 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0244734 |
| UBC | ubiquitin C | -0.0244555 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0242658 |
| SYAP1 | synapse associated protein 1 | -0.024225 |
| ETV6 | ets variant 6 | -0.0239948 |
| RPL7 | ribosomal protein L7 | -0.0239902 |
| HDAC4 | histone deacetylase 4 | -0.0239824 |
| RPL23 | ribosomal protein L23 | -0.0239738 |
| TXNRD1 | thioredoxin reductase 1 | -0.0239001 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0237502 |
| LOXL2 | lysyl oxidase-like 2 | -0.0236767 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.023618 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0236065 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.02332 |
| RPS21 | ribosomal protein S21 | -0.0230789 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0230688 |
| RPL35A | ribosomal protein L35a | -0.0229057 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0227491 |
| RPL9 | ribosomal protein L9 | -0.0227482 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0227151 |
| ZNF385D | zinc finger protein 385D | -0.0226781 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0225991 |
| TMEM263 | transmembrane protein 263 | -0.0225302 |
| H3-3B | H3.3 histone B | -0.0223705 |