| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.201616 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.190333 |
| VIM | vimentin | 0.141878 |
| ACTG1 | actin gamma 1 | 0.120989 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0923698 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0823192 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0789663 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0777039 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0770611 |
| POTEF | POTE ankyrin domain family, member F | 0.0722152 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0699061 |
| TPD52 | tumor protein D52 | 0.0567237 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0559908 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0556684 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0544439 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0543779 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0543758 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0508116 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.047629 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0469042 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0467292 |
| PLS3 | plastin 3 | 0.0463944 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0463434 |
| TFG | TRK-fused gene | 0.0460061 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.04548 |
| TPM4 | tropomyosin 4 | 0.0454103 |
| THBS1 | thrombospondin 1 | 0.045204 |
| KLF6 | Kruppel-like factor 6 | 0.0444253 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0442699 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0441369 |
| PRR16 | proline rich 16 | 0.0441202 |
| RNF145 | ring finger protein 145 | 0.0430213 |
| IL6 | interleukin 6 | 0.0425109 |
| FMNL2 | formin-like 2 | 0.0419559 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0416346 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0407703 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.03924 |
| FAM168A | family with sequence similarity 168, member A | 0.0381469 |
| NEGR1 | neuronal growth regulator 1 | 0.0378624 |
| CHN1 | chimerin 1 | 0.037743 |
| COPA | coatomer protein complex, subunit alpha | 0.0377041 |
| HDAC9 | histone deacetylase 9 | 0.0372124 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0372113 |
| AHR | aryl hydrocarbon receptor | 0.0369972 |
| GNAS | GNAS complex locus | 0.0367654 |
| LDHA | lactate dehydrogenase A | 0.0366761 |
| DEK | DEK proto-oncogene | 0.0365235 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0361332 |
| YME1L1 | YME1-like 1 ATPase | 0.0359694 |
| WDR43 | WD repeat domain 43 | 0.0356492 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.035422 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0348811 |
| FNBP1L | formin binding protein 1-like | 0.0348158 |
| ENO1 | enolase 1, (alpha) | 0.0346622 |
| S100A10 | S100 calcium binding protein A10 | 0.0341573 |
| S100A6 | S100 calcium binding protein A6 | 0.0338373 |
| DST | dystonin | 0.0336984 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0334378 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0333305 |
| MITF | microphthalmia-associated transcription factor | 0.0331484 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0331345 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0331238 |
| IGF2 | insulin-like growth factor 2 | 0.0331231 |
| FLNB | filamin B, beta | 0.0328949 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0323853 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0323716 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0321408 |
| SRGN | serglycin | 0.0320829 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0319581 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.03149 |
| MORF4L1 | mortality factor 4 like 1 | 0.0310037 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0309783 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0306024 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.0304137 |
| ANXA1 | annexin A1 | 0.0303981 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0299391 |
| RBM25 | RNA binding motif protein 25 | 0.0297669 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0292295 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0288218 |
| PDLIM5 | PDZ and LIM domain 5 | 0.028743 |
| ANKRD11 | ankyrin repeat domain 11 | 0.028714 |
| CD109 | CD109 molecule | 0.0281126 |
| RAB18 | RAB18, member RAS oncogene family | 0.0279616 |
| MTMR3 | myotubularin related protein 3 | 0.0277647 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0277363 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0276678 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0275866 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0275429 |
| SEPTIN7 | septin 7 | 0.027537 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0274463 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0273734 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0273396 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0272813 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0272353 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0272023 |
| TPR | translocated promoter region, nuclear basket protein | 0.0271033 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0270304 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.026889 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0268309 |
| WDR36 | WD repeat domain 36 | 0.0267881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | -0.168964 |
| GRAMD1B | GRAM domain containing 1B | -0.157967 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.128372 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.11285 |
| MT2A | metallothionein 2A | -0.0870877 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0674783 |
| RPL19 | ribosomal protein L19 | -0.0658375 |
| RPS2 | ribosomal protein S2 | -0.0641801 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0626225 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0622361 |
| BRD2 | bromodomain containing 2 | -0.0585325 |
| FTL | ferritin, light polypeptide | -0.0581492 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0552353 |
| WWOX | WW domain containing oxidoreductase | -0.0551204 |
| USP34 | ubiquitin specific peptidase 34 | -0.0548874 |
| TMSB10 | thymosin beta 10 | -0.0548044 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0544049 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0521195 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0515623 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0495095 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0467156 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0457811 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0455256 |
| CMIP | c-Maf inducing protein | -0.0453948 |
| ASPH | aspartate beta-hydroxylase | -0.044935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0445954 |
| EGR1 | early growth response 1 | -0.0440145 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0439373 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0429274 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0425226 |
| RBM39 | RNA binding motif protein 39 | -0.0415729 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.041408 |
| CENPF | centromere protein F, 350/400kDa | -0.0401734 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0393769 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0383866 |
| AURKA | aurora kinase A | -0.0383292 |
| ADAR | adenosine deaminase, RNA-specific | -0.0381537 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0380711 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0377581 |
| RPLP1 | ribosomal protein, large, P1 | -0.03672 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0365793 |
| RTN4 | reticulon 4 | -0.0362145 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.036158 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0354614 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0344194 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0342278 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0332809 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0327352 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0327325 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0326812 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0326058 |
| MCL1 | myeloid cell leukemia 1 | -0.0323938 |
| ATP11A | ATPase, class VI, type 11A | -0.0323863 |
| TXNRD1 | thioredoxin reductase 1 | -0.0323838 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0323747 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0316442 |
| YBX1 | Y box binding protein 1 | -0.031526 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0314914 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0314362 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0313376 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0313036 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0308773 |
| SERINC3 | serine incorporator 3 | -0.0308447 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.030576 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0299086 |
| CENPE | centromere protein E, 312kDa | -0.0298559 |
| RPL7 | ribosomal protein L7 | -0.0296045 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.029529 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.029232 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0291208 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0290849 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0286737 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0284385 |
| RAB10 | RAB10, member RAS oncogene family | -0.0283874 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0283754 |
| SMYD3 | SET and MYND domain containing 3 | -0.0279298 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0278614 |
| RCOR1 | REST corepressor 1 | -0.0278315 |
| CBFB | core-binding factor, beta subunit | -0.0273997 |
| BMP6 | bone morphogenetic protein 6 | -0.0273613 |
| ATXN1 | ataxin 1 | -0.0270757 |
| GOLGB1 | golgin B1 | -0.0270675 |
| PHF3 | PHD finger protein 3 | -0.0270476 |
| GPHN | gephyrin | -0.0270357 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0270134 |
| SVIL | supervillin | -0.0269277 |
| EXOC6B | exocyst complex component 6B | -0.026656 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0264266 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0261885 |
| SGO2 | shugoshin 2 | -0.0259818 |
| APP | amyloid beta (A4) precursor protein | -0.0259094 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.025814 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | -0.0257854 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0254223 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0253001 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0252122 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0252077 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0251505 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0249838 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0248926 |
