| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0907604 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.071721 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0513615 |
| OGA | O-GlcNAcase | 0.0486357 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0465833 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.045851 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0449498 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0448221 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0398803 |
| DIAPH3 | diaphanous-related formin 3 | 0.0397593 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0367653 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0360241 |
| SET | SET nuclear proto-oncogene | 0.0344425 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0331987 |
| PHF20 | PHD finger protein 20 | 0.0320331 |
| VIM | vimentin | 0.031933 |
| AHNAK | AHNAK nucleoprotein | 0.0315842 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0313968 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0307167 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0301486 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0298996 |
| NCKAP1 | NCK-associated protein 1 | 0.0297902 |
| XPOT | exportin, tRNA | 0.0285772 |
| NUP58 | nucleoporin 58 | 0.0284608 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0277875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0275928 |
| SMAD3 | SMAD family member 3 | 0.027476 |
| RAP1A | RAP1A, member of RAS oncogene family | 0.0271266 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0269251 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.026255 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0262001 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0257661 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0257469 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0256319 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0246679 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.0246213 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0245254 |
| MELK | maternal embryonic leucine zipper kinase | 0.0244635 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0240434 |
| RPL4 | ribosomal protein L4 | 0.0239445 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.023769 |
| AFTPH | aftiphilin | 0.02365 |
| FAM199X | family with sequence similarity 199, X-linked | 0.0234818 |
| TFG | TRK-fused gene | 0.0234297 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.023401 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0231459 |
| TMEM165 | transmembrane protein 165 | 0.0229444 |
| FAM168A | family with sequence similarity 168, member A | 0.0228712 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0228627 |
| PRKD3 | protein kinase D3 | 0.0226198 |
| KIF13A | kinesin family member 13A | 0.0224667 |
| PGK1 | phosphoglycerate kinase 1 | 0.0223403 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0222692 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0222521 |
| USP37 | ubiquitin specific peptidase 37 | 0.0222114 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0221963 |
| CGAS | cyclic GMP-AMP synthase | 0.0220016 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0219831 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0218797 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.021757 |
| IPO5 | importin 5 | 0.0217537 |
| TMEM41B | transmembrane protein 41B | 0.0215174 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.02133 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0212492 |
| USP34 | ubiquitin specific peptidase 34 | 0.0207816 |
| PRELID2 | PRELI domain containing 2 | 0.0207255 |
| PHF21A | PHD finger protein 21A | 0.0207224 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0205277 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0204745 |
| CPNE8 | copine VIII | 0.020382 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0203218 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0201981 |
| KRT8 | keratin 8, type II | 0.0201734 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0200927 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0200361 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.020026 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0198495 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0197493 |
| TPM2 | tropomyosin 2 (beta) | 0.019703 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0196872 |
| HDGF | hepatoma-derived growth factor | 0.0196407 |
| SSH2 | slingshot protein phosphatase 2 | 0.0196316 |
| NUP153 | nucleoporin 153kDa | 0.0194694 |
| PREPL | prolyl endopeptidase-like | 0.0194165 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0193194 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0192239 |
| RPL37A | ribosomal protein L37a | 0.0192093 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0191697 |
| DAPK3 | death-associated protein kinase 3 | 0.0189717 |
| TMEM123 | transmembrane protein 123 | 0.0188716 |
| CTTN | cortactin | 0.0188658 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0188138 |
| PHIP | pleckstrin homology domain interacting protein | 0.0186649 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0185576 |
| ATP13A3 | ATPase type 13A3 | 0.0185169 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0184948 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0184321 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.0184312 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0184139 |
| MED14 | mediator complex subunit 14 | 0.0184086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.166768 |
| YBX3 | Y box binding protein 3 | -0.127517 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.121518 |
| MCL1 | myeloid cell leukemia 1 | -0.0902174 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0850816 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0847425 |
| BRD2 | bromodomain containing 2 | -0.0803145 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0802743 |
| TPI1 | triosephosphate isomerase 1 | -0.0765825 |
| YBX1 | Y box binding protein 1 | -0.0745577 |
| TMSB10 | thymosin beta 10 | -0.0738176 |
| NABP1 | nucleic acid binding protein 1 | -0.0667471 |
| TXNRD1 | thioredoxin reductase 1 | -0.0644054 |
| GRAMD1B | GRAM domain containing 1B | -0.062289 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0621248 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0593646 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0580047 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0558661 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0533606 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0530695 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0519963 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0514847 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0503248 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0500884 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0496807 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0477036 |
| CENPF | centromere protein F, 350/400kDa | -0.047571 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0461429 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0452388 |
| ADAR | adenosine deaminase, RNA-specific | -0.0451058 |
| BSG | basigin (Ok blood group) | -0.0450493 |
| CLTC | clathrin, heavy chain (Hc) | -0.0450024 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0448649 |
| POTEF | POTE ankyrin domain family, member F | -0.0447961 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0436019 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0422517 |
| PCBP2 | poly(rC) binding protein 2 | -0.0422439 |
| PFN1 | profilin 1 | -0.0420934 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0419988 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0412275 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0409637 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0408384 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0402398 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0399968 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0393244 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0388941 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0386593 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0385917 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0381955 |
| GOLGB1 | golgin B1 | -0.0375624 |
| PHF3 | PHD finger protein 3 | -0.0374465 |
| NLGN1 | neuroligin 1 | -0.0371077 |
| HDLBP | high density lipoprotein binding protein | -0.0366599 |
| BPTF | bromodomain PHD finger transcription factor | -0.0365141 |
| ATP11A | ATPase, class VI, type 11A | -0.036278 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0357492 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0356535 |
| PRRC2A | proline-rich coiled-coil 2A | -0.0354855 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0349008 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0346173 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0344645 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0342521 |
| CMIP | c-Maf inducing protein | -0.0340928 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0340151 |
| TAOK1 | TAO kinase 1 | -0.0333339 |
| INTS6 | integrator complex subunit 6 | -0.0331817 |
| EP400 | E1A binding protein p400 | -0.0326346 |
| MEF2D | myocyte enhancer factor 2D | -0.0325332 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0323808 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0323392 |
| ZNF644 | zinc finger protein 644 | -0.0319993 |
| PYGL | phosphorylase, glycogen, liver | -0.0319873 |
| GPHN | gephyrin | -0.031838 |
| RPS2 | ribosomal protein S2 | -0.0318155 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0317209 |
| PER1 | period circadian clock 1 | -0.0314652 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0310524 |
| RBM39 | RNA binding motif protein 39 | -0.0307262 |
| TAPBP | TAP binding protein (tapasin) | -0.0295642 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295298 |
| ACTG1 | actin gamma 1 | -0.0286803 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0286068 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0285298 |
| ACTN1 | actinin, alpha 1 | -0.0282879 |
| CDK17 | cyclin-dependent kinase 17 | -0.0282435 |
| KRT18 | keratin 18, type I | -0.0277426 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0277302 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0271261 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0270782 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.027027 |
| RPL38 | ribosomal protein L38 | -0.0269809 |
| PKM | pyruvate kinase, muscle | -0.0269699 |
| RPL3 | ribosomal protein L3 | -0.0268713 |
| JMJD1C | jumonji domain containing 1C | -0.0267982 |
| RTN4 | reticulon 4 | -0.0267967 |
| GSE1 | Gse1 coiled-coil protein | -0.0266779 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | -0.026406 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0260827 |
| LRRC23 | leucine rich repeat containing 23 | -0.025856 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0258135 |