| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0817414 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0744273 |
| LAMB3 | laminin, beta 3 | 0.0672211 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.066534 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0662741 |
| SQSTM1 | sequestosome 1 | 0.0623471 |
| RPS6 | ribosomal protein S6 | 0.0589088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0552577 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0541179 |
| LAMC2 | laminin, gamma 2 | 0.0526426 |
| NCKAP1 | NCK-associated protein 1 | 0.052492 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0514193 |
| SET | SET nuclear proto-oncogene | 0.0465235 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0463458 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0444839 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.042507 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0424127 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0422768 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0421815 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0416158 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0403244 |
| RPS12 | ribosomal protein S12 | 0.0397127 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0385989 |
| DSPP | dentin sialophosphoprotein | 0.0384228 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0372359 |
| RPS2 | ribosomal protein S2 | 0.0353429 |
| ASPH | aspartate beta-hydroxylase | 0.0346741 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0339767 |
| PEG10 | paternally expressed 10 | 0.0337851 |
| CCND1 | cyclin D1 | 0.0337206 |
| PGK1 | phosphoglycerate kinase 1 | 0.0335366 |
| RACK1 | receptor for activated C kinase 1 | 0.033298 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0323748 |
| ZNF292 | zinc finger protein 292 | 0.0307957 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0306711 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0306079 |
| EREG | epiregulin | 0.0299014 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0298286 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0297449 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0286812 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0283968 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0281489 |
| RPS3 | ribosomal protein S3 | 0.0281331 |
| SLMAP | sarcolemma associated protein | 0.0276955 |
| MATR3 | matrin 3 | 0.027428 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0271186 |
| ANXA1 | annexin A1 | 0.026761 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.026733 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0266659 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0266363 |
| RPS8 | ribosomal protein S8 | 0.0265965 |
| NUP58 | nucleoporin 58 | 0.0265759 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0263166 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0256901 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0248745 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0248187 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0247293 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0242818 |
| YME1L1 | YME1-like 1 ATPase | 0.0237204 |
| FAM13A | family with sequence similarity 13, member A | 0.0231471 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0228473 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0227182 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0224275 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.022419 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0222503 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0222009 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0218379 |
| MKI67 | marker of proliferation Ki-67 | 0.0218019 |
| ARRDC3 | arrestin domain containing 3 | 0.0217848 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.02175 |
| IRF6 | interferon regulatory factor 6 | 0.021518 |
| RPL26 | ribosomal protein L26 | 0.021324 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0211778 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.021143 |
| SCEL | sciellin | 0.0208709 |
| STAG2 | stromal antigen 2 | 0.0208516 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0207515 |
| RPS17 | ribosomal protein S17 | 0.0206058 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0204952 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0204747 |
| CBX3 | chromobox homolog 3 | 0.0204515 |
| LDHB | lactate dehydrogenase B | 0.0203543 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.020334 |
| ITGAV | integrin, alpha V | 0.0202956 |
| WDR36 | WD repeat domain 36 | 0.0202156 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0196956 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0196018 |
| OGA | O-GlcNAcase | 0.0194575 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0194334 |
| FHIT | fragile histidine triad | 0.0193953 |
| WDR43 | WD repeat domain 43 | 0.0193913 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0193173 |
| SERINC1 | serine incorporator 1 | 0.0192337 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0192317 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0191783 |
| RPL7 | ribosomal protein L7 | 0.0190327 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0189945 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0188886 |
| KIF5B | kinesin family member 5B | 0.0188416 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0186558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.265576 |
| FTL | ferritin, light polypeptide | -0.22413 |
| TMSB10 | thymosin beta 10 | -0.148287 |
| NDRG1 | N-myc downstream regulated 1 | -0.141191 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.111448 |
| POTEF | POTE ankyrin domain family, member F | -0.10817 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0999946 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0855162 |
| TSC22D2 | TSC22 domain family, member 2 | -0.081231 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0753471 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0748509 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0725258 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0714306 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0695857 |
| LDHA | lactate dehydrogenase A | -0.0678203 |
| LMO7 | LIM domain 7 | -0.0619317 |
| EFNA5 | ephrin-A5 | -0.0614394 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0602313 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0599411 |
| BRD2 | bromodomain containing 2 | -0.0563767 |
| HLA-A | major histocompatibility complex, class I, A | -0.0561103 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0545431 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0536755 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0527524 |
| RPLP1 | ribosomal protein, large, P1 | -0.0497088 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0488483 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0483617 |
| TMEM263 | transmembrane protein 263 | -0.0482132 |
| TAPBP | TAP binding protein (tapasin) | -0.0459063 |
| FNIP1 | folliculin interacting protein 1 | -0.0455643 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0447524 |
| FAM3C | family with sequence similarity 3, member C | -0.0444115 |
| VEGFA | vascular endothelial growth factor A | -0.0436001 |
| PCBP2 | poly(rC) binding protein 2 | -0.0429419 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0427887 |
| HLA-B | major histocompatibility complex, class I, B | -0.0423183 |
| ARF4 | ADP-ribosylation factor 4 | -0.0414424 |
| MYO1E | myosin IE | -0.0410062 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0407794 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0405974 |
| WASF2 | WAS protein family, member 2 | -0.040263 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0401381 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0399986 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0393918 |
| HDLBP | high density lipoprotein binding protein | -0.039135 |
| MCL1 | myeloid cell leukemia 1 | -0.0390306 |
| EGR1 | early growth response 1 | -0.0387604 |
| RPS19 | ribosomal protein S19 | -0.0386744 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0386602 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0380642 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0376543 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0376445 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0374736 |
| SDC4 | syndecan 4 | -0.0373527 |
| GOLGB1 | golgin B1 | -0.0372227 |
| TMEM165 | transmembrane protein 165 | -0.0369732 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0362546 |
| MCU | mitochondrial calcium uniporter | -0.0358736 |
| MT2A | metallothionein 2A | -0.0358353 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0353661 |
| RCOR1 | REST corepressor 1 | -0.0352228 |
| RPL35A | ribosomal protein L35a | -0.0344429 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0341729 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0338587 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0336657 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0336195 |
| TXNIP | thioredoxin interacting protein | -0.0335135 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0333968 |
| COPA | coatomer protein complex, subunit alpha | -0.0331291 |
| TJP1 | tight junction protein 1 | -0.0330448 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0330389 |
| CDCP1 | CUB domain containing protein 1 | -0.0325328 |
| CLDN4 | claudin 4 | -0.0322904 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0322564 |
| LMNA | lamin A/C | -0.0319696 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0317217 |
| KLHL24 | kelch-like family member 24 | -0.031389 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0312049 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0308934 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0308791 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.030855 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0301939 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0300959 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0300875 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0299197 |
| PKM | pyruvate kinase, muscle | -0.0298311 |
| PTK2 | protein tyrosine kinase 2 | -0.0295017 |
| PALLD | palladin, cytoskeletal associated protein | -0.0292924 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0292542 |
| OCLN | occludin | -0.0291811 |
| F11R | F11 receptor | -0.0291473 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0288437 |
| ATOSA | atos homolog A | -0.0287535 |
| TPM4 | tropomyosin 4 | -0.0287019 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0282076 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0281979 |
| VMP1 | vacuole membrane protein 1 | -0.028128 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0281264 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0280796 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0277764 |