| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.170894 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.148389 |
| EFNA5 | ephrin-A5 | 0.138686 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.135721 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.087242 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.079369 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0790033 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0782916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0745665 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0738399 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0728617 |
| FAM13A | family with sequence similarity 13, member A | 0.0726611 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0710913 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0710631 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.070223 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0691596 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0691451 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0690604 |
| RPS6 | ribosomal protein S6 | 0.0685379 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0679579 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0656109 |
| OGA | O-GlcNAcase | 0.0648748 |
| ASPH | aspartate beta-hydroxylase | 0.0646856 |
| NEK7 | NIMA-related kinase 7 | 0.0640353 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0595665 |
| MCL1 | myeloid cell leukemia 1 | 0.0593067 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0584449 |
| RNF145 | ring finger protein 145 | 0.0578457 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0567439 |
| RTN4 | reticulon 4 | 0.0560037 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0558135 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0555948 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0547987 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0536116 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0533863 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.052967 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0525385 |
| NCKAP1 | NCK-associated protein 1 | 0.051471 |
| NUP58 | nucleoporin 58 | 0.0507643 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0505658 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0504065 |
| SPAG9 | sperm associated antigen 9 | 0.049978 |
| FLNB | filamin B, beta | 0.0498743 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0495007 |
| HELZ | helicase with zinc finger | 0.0494589 |
| ZNF292 | zinc finger protein 292 | 0.0491137 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0490837 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0490386 |
| TPD52 | tumor protein D52 | 0.0474909 |
| SET | SET nuclear proto-oncogene | 0.0467995 |
| MXI1 | MAX interactor 1, dimerization protein | 0.046488 |
| KYNU | kynureninase | 0.0464802 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0463685 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0460292 |
| NGLY1 | N-glycanase 1 | 0.0459929 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0456754 |
| CCDC88A | coiled-coil domain containing 88A | 0.0453062 |
| CTSC | cathepsin C | 0.0443795 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.044314 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0442101 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0438371 |
| MATR3 | matrin 3 | 0.0428678 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0423364 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0422464 |
| FMNL2 | formin-like 2 | 0.0414221 |
| MFF | mitochondrial fission factor | 0.0410475 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.040973 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0409222 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0408413 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0405442 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0402597 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0400848 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0392937 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0392589 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0389164 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0386787 |
| USP34 | ubiquitin specific peptidase 34 | 0.0385566 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0385223 |
| RPS12 | ribosomal protein S12 | 0.0381638 |
| RAI1 | retinoic acid induced 1 | 0.0374853 |
| CEP170 | centrosomal protein 170kDa | 0.0374823 |
| ATP13A3 | ATPase type 13A3 | 0.0373997 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0373418 |
| XPO1 | exportin 1 | 0.0367476 |
| ZNF638 | zinc finger protein 638 | 0.0365666 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0362171 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0360562 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0358448 |
| USP3 | ubiquitin specific peptidase 3 | 0.0355909 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0353994 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0353396 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0353213 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0352086 |
| OLA1 | Obg-like ATPase 1 | 0.0350398 |
| RPL12 | ribosomal protein L12 | 0.034934 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0347991 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0347046 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.034692 |
| MED13 | mediator complex subunit 13 | 0.0346225 |
| PHF20 | PHD finger protein 20 | 0.0344578 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.20063 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.105067 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0891503 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0641683 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0625836 |
| CDH13 | cadherin 13 | -0.0613685 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.060947 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0573259 |
| LDHA | lactate dehydrogenase A | -0.056904 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0554049 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.05366 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0535152 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0503978 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0466344 |
| RPL31 | ribosomal protein L31 | -0.0451462 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.042693 |
| HLA-B | major histocompatibility complex, class I, B | -0.0386326 |
| GDA | guanine deaminase | -0.0377322 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0355747 |
| COL5A2 | collagen, type V, alpha 2 | -0.0346419 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0345267 |
| RIGI | RNA sensor RIG-I | -0.0321674 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.031971 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.03176 |
| PDE10A | phosphodiesterase 10A | -0.0311184 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0307921 |
| ANTXR1 | anthrax toxin receptor 1 | -0.030312 |
| EGR1 | early growth response 1 | -0.0302387 |
| RPL38 | ribosomal protein L38 | -0.0298401 |
| INTS6 | integrator complex subunit 6 | -0.0294329 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0287566 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0285116 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0285076 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0276216 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0274892 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0268272 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0267242 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0267017 |
| RPL13A | ribosomal protein L13a | -0.0266448 |
| RHOB | ras homolog family member B | -0.0266053 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0261965 |
| RGS2 | regulator of G-protein signaling 2 | -0.0259345 |
| NRCAM | neuronal cell adhesion molecule | -0.0249428 |
| TMSB10 | thymosin beta 10 | -0.0248063 |
| ARF1 | ADP-ribosylation factor 1 | -0.0240334 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0236314 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0231716 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.0231574 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0229494 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0224925 |
| AEBP2 | AE binding protein 2 | -0.0223685 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0219634 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0217248 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0217068 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.021662 |
| HLA-A | major histocompatibility complex, class I, A | -0.0215701 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0214603 |
| SQSTM1 | sequestosome 1 | -0.0214028 |
| RPS24 | ribosomal protein S24 | -0.021124 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0207449 |
| CD44 | CD44 molecule (Indian blood group) | -0.0207209 |
| KIAA0825 | KIAA0825 | -0.0205197 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0201293 |
| HDAC8 | histone deacetylase 8 | -0.0196114 |
| ACTG1 | actin gamma 1 | -0.0195453 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0193135 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0190918 |
| IGF2 | insulin-like growth factor 2 | -0.0188642 |
| NCKAP5 | NCK-associated protein 5 | -0.0186369 |
| RPLP1 | ribosomal protein, large, P1 | -0.0186103 |
| VCL | vinculin | -0.018347 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0179065 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0178795 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0178701 |
| CTSD | cathepsin D | -0.0177921 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.0177387 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0176605 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0175984 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.017407 |
| CDK6 | cyclin-dependent kinase 6 | -0.0173007 |
| JUN | jun proto-oncogene | -0.0172734 |
| TBXT | T-box transcription factor T | -0.0170877 |
| PALLD | palladin, cytoskeletal associated protein | -0.017021 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0169549 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0168569 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0167679 |
| CMIP | c-Maf inducing protein | -0.0166792 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0166266 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0165336 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0162224 |
| RRBP1 | ribosome binding protein 1 | -0.0162149 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0162016 |
| HMGA1 | high mobility group AT-hook 1 | -0.0161331 |
| GOLGB1 | golgin B1 | -0.0160707 |
| HLA-E | major histocompatibility complex, class I, E | -0.0159617 |
| MYO1E | myosin IE | -0.0159531 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0159234 |
| STK17A | serine/threonine kinase 17a | -0.015822 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0157927 |
| SVIL | supervillin | -0.0157917 |
