| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.143882 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.13873 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.138421 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.136621 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.13316 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.122709 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.117603 |
| TSC22D2 | TSC22 domain family, member 2 | 0.111502 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.110135 |
| CD44 | CD44 molecule (Indian blood group) | 0.108448 |
| GRB10 | growth factor receptor-bound protein 10 | 0.106772 |
| CALU | calumenin | 0.0990414 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0988089 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0985669 |
| SPAG9 | sperm associated antigen 9 | 0.0935757 |
| S100A10 | S100 calcium binding protein A10 | 0.0911517 |
| TXNRD1 | thioredoxin reductase 1 | 0.0834596 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0823042 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0809415 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0805998 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.07821 |
| DTNA | dystrobrevin, alpha | 0.0752979 |
| OGA | O-GlcNAcase | 0.0750756 |
| ANXA2 | annexin A2 | 0.0712994 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0708981 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0691748 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0691406 |
| TOP1 | topoisomerase (DNA) I | 0.0686218 |
| ACTN4 | actinin, alpha 4 | 0.068447 |
| TMSB10 | thymosin beta 10 | 0.068215 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0653017 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0642323 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0634152 |
| SRPK2 | SRSF protein kinase 2 | 0.0633472 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0613651 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0610031 |
| NDRG1 | N-myc downstream regulated 1 | 0.060675 |
| SLTM | SAFB-like, transcription modulator | 0.0606503 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.057659 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0576505 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0575392 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0551608 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0547785 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0545202 |
| ATXN1 | ataxin 1 | 0.0538104 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0518359 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.051597 |
| COG5 | component of oligomeric golgi complex 5 | 0.0507457 |
| ACTG1 | actin gamma 1 | 0.0495729 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0489206 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0473938 |
| FLNB | filamin B, beta | 0.0468676 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0454522 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0441282 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0437116 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0431536 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0423327 |
| SMAD3 | SMAD family member 3 | 0.0413351 |
| PDE10A | phosphodiesterase 10A | 0.0374621 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0368506 |
| EZR | ezrin | 0.0367588 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0363836 |
| COL5A2 | collagen, type V, alpha 2 | 0.0360112 |
| MED13L | mediator complex subunit 13-like | 0.0357479 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0357461 |
| RBM39 | RNA binding motif protein 39 | 0.033127 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0331246 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0327424 |
| PRKD3 | protein kinase D3 | 0.0319066 |
| STC1 | stanniocalcin 1 | 0.0308701 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029862 |
| FN1 | fibronectin 1 | 0.0289962 |
| GPC6 | glypican 6 | 0.028239 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0279428 |
| NFIA | nuclear factor I/A | 0.0266321 |
| MATR3 | matrin 3 | 0.0242134 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0235725 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0231568 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0200199 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0198174 |
| HDLBP | high density lipoprotein binding protein | 0.019282 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0182984 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0164315 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0162934 |
| TCF12 | transcription factor 12 | 0.0160445 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0158844 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0148532 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0141119 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0123067 |
| EGFR | epidermal growth factor receptor | 0.0111 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.00879103 |
| CERS6 | ceramide synthase 6 | 0.00726029 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00598014 |
| USP34 | ubiquitin specific peptidase 34 | 0.00540266 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00517433 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00472764 |
| ARRDC3 | arrestin domain containing 3 | 0.00359844 |
| BBX | bobby sox homolog (Drosophila) | 0.00325843 |
| CANX | calnexin | 0.00325499 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00318225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.212237 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205128 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.155297 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.153199 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.119916 |
| JMJD1C | jumonji domain containing 1C | -0.108491 |
| GOLGB1 | golgin B1 | -0.101228 |
| RPS19 | ribosomal protein S19 | -0.0999056 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0990181 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0900321 |
| RPS6 | ribosomal protein S6 | -0.0883797 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0864085 |
| VCL | vinculin | -0.0846405 |
| GOLGA4 | golgin A4 | -0.0803612 |
| HMGA2 | high mobility group AT-hook 2 | -0.0793201 |
| RORA | RAR-related orphan receptor A | -0.0792186 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0764448 |
| PRKCA | protein kinase C, alpha | -0.0752061 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0705013 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0681484 |
| NAV2 | neuron navigator 2 | -0.0632274 |
| CADM2 | cell adhesion molecule 2 | -0.0628792 |
| LMO7 | LIM domain 7 | -0.06281 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0609767 |
| ATP11A | ATPase, class VI, type 11A | -0.0606526 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0604435 |
| FTL | ferritin, light polypeptide | -0.060374 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0599907 |
| NBEAL1 | neurobeachin-like 1 | -0.059622 |
| RBM25 | RNA binding motif protein 25 | -0.0586968 |
| B2M | beta-2-microglobulin | -0.0578096 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0566314 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0566172 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0564882 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.054319 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0535362 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.051544 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0511944 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0500289 |
| FNIP1 | folliculin interacting protein 1 | -0.0498764 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.04914 |
| CALR | calreticulin | -0.0488876 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0467312 |
| MYO1E | myosin IE | -0.0464719 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0462179 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0455256 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.043647 |
| H3-3B | H3.3 histone B | -0.0432492 |
| ZNF608 | zinc finger protein 608 | -0.0429917 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0420626 |
| PKM | pyruvate kinase, muscle | -0.0414684 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0398985 |
| MT2A | metallothionein 2A | -0.039419 |
| TXNIP | thioredoxin interacting protein | -0.0394144 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0392296 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.039169 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376446 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0376223 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0348059 |
| MORF4L2 | mortality factor 4 like 2 | -0.0344021 |
| PTMA | prothymosin, alpha | -0.0334024 |
| PEG10 | paternally expressed 10 | -0.0326695 |
| IGF2 | insulin-like growth factor 2 | -0.0321261 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0319073 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0316662 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0311955 |
| RPL35A | ribosomal protein L35a | -0.0308882 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0305616 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0301549 |
| MED13 | mediator complex subunit 13 | -0.0293221 |
| MYOF | myoferlin | -0.0290409 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0287358 |
| DST | dystonin | -0.0284996 |
| PTK2 | protein tyrosine kinase 2 | -0.0281235 |
| SMYD3 | SET and MYND domain containing 3 | -0.0274286 |
| TNS3 | tensin 3 | -0.027282 |
| PGK1 | phosphoglycerate kinase 1 | -0.0263626 |
| ASPH | aspartate beta-hydroxylase | -0.0262056 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0261108 |
| PARD3 | par-3 family cell polarity regulator | -0.025971 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0258771 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239507 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.023873 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0228909 |
| AFDN | afadin, adherens junction formation factor | -0.0222519 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0219551 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0210307 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0205619 |
| TENM3 | teneurin transmembrane protein 3 | -0.0205132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0204102 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0194865 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.019397 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0193923 |
| FBXO11 | F-box protein 11 | -0.0182666 |
| SYAP1 | synapse associated protein 1 | -0.0181531 |
| SETD5 | SET domain containing 5 | -0.0171103 |
| CUL3 | cullin 3 | -0.0169015 |
| FAM13A | family with sequence similarity 13, member A | -0.0164281 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0151753 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0143285 |
