| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | 0.0765096 |
| MKI67 | marker of proliferation Ki-67 | 0.0727061 |
| NCKAP1 | NCK-associated protein 1 | 0.0523677 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0468315 |
| H1-4 | H1.4 linker histone, cluster member | 0.0459277 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0446352 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0434599 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0414586 |
| WDR43 | WD repeat domain 43 | 0.0413435 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0401957 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0378131 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.035738 |
| LUZP2 | leucine zipper protein 2 | 0.0351202 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0350685 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0334818 |
| OLA1 | Obg-like ATPase 1 | 0.0334145 |
| SET | SET nuclear proto-oncogene | 0.0323093 |
| ANXA1 | annexin A1 | 0.0318122 |
| RHEB | Ras homolog enriched in brain | 0.0311223 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0302008 |
| PLPP1 | phospholipid phosphatase 1 | 0.0288728 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0282693 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0278606 |
| PDGFC | platelet derived growth factor C | 0.0278169 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0274788 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0271189 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0263847 |
| MEF2A | myocyte enhancer factor 2A | 0.0263249 |
| KIF11 | kinesin family member 11 | 0.0258551 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0256084 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.025467 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.025372 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0250666 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0247705 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0244989 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0244838 |
| RPS2 | ribosomal protein S2 | 0.0243195 |
| SP3 | Sp3 transcription factor | 0.0240216 |
| COL1A2 | collagen, type I, alpha 2 | 0.0240138 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0232432 |
| CLSPN | claspin | 0.0227977 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | 0.0225148 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0225143 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0225127 |
| USP3 | ubiquitin specific peptidase 3 | 0.02236 |
| ERBIN | erbb2 interacting protein | 0.0221573 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0220806 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0219673 |
| RPS12 | ribosomal protein S12 | 0.0217384 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.021703 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0216969 |
| CLINT1 | clathrin interactor 1 | 0.0216636 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0214412 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0213809 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0212943 |
| LCA5 | Leber congenital amaurosis 5 | 0.021117 |
| PDE8A | phosphodiesterase 8A | 0.0210543 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0206025 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0206009 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0205952 |
| USP33 | ubiquitin specific peptidase 33 | 0.0204996 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0204831 |
| TNPO1 | transportin 1 | 0.0203779 |
| RYBP | RING1 and YY1 binding protein | 0.0202762 |
| PDS5B | PDS5 cohesin associated factor B | 0.0202491 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0201825 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0200836 |
| PARD3B | par-3 family cell polarity regulator beta | 0.020054 |
| ZNF451 | zinc finger protein 451 | 0.0200459 |
| FOXP2 | forkhead box P2 | 0.019918 |
| TSPAN12 | tetraspanin 12 | 0.0198278 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0197014 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0195706 |
| MEMO1 | mediator of cell motility 1 | 0.0194574 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0194358 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0193673 |
| CDC42 | cell division cycle 42 | 0.0193414 |
| TBC1D12 | TBC1 domain family, member 12 | 0.01934 |
| SPOPL | speckle-type POZ protein-like | 0.0192178 |
| DIAPH3 | diaphanous-related formin 3 | 0.0191323 |
| RBMX | RNA binding motif protein, X-linked | 0.018911 |
| SELENOI | selenoprotein I | 0.0188578 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0187506 |
| H2AZ2 | H2A.Z variant histone 2 | 0.0187113 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.0186906 |
| KIF1B | kinesin family member 1B | 0.0185884 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.018535 |
| RBM33 | RNA binding motif protein 33 | 0.0185081 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.018291 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0182352 |
| NCOR1 | nuclear receptor corepressor 1 | 0.018197 |
| BTG3 | BTG family, member 3 | 0.018015 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0180036 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0177488 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0176671 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0175635 |
| MTF2 | metal response element binding transcription factor 2 | 0.0175277 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0175007 |
| UPP1 | uridine phosphorylase 1 | 0.0173267 |
| RBM26 | RNA binding motif protein 26 | 0.0172883 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.245661 |
| COL11A1 | collagen, type XI, alpha 1 | -0.168123 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.157819 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.110833 |
| GPC3 | glypican 3 | -0.110613 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0989661 |
| PEG10 | paternally expressed 10 | -0.0984731 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0982714 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0953109 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.086809 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0695433 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0662737 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0643926 |
| RPS16 | ribosomal protein S16 | -0.0629628 |
| RPL35A | ribosomal protein L35a | -0.0596206 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0593154 |
| FN1 | fibronectin 1 | -0.05825 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0575804 |
| PFN1 | profilin 1 | -0.0574304 |
| CADM2 | cell adhesion molecule 2 | -0.0555387 |
| RPLP0 | ribosomal protein, large, P0 | -0.0555177 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.054218 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0538554 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0538443 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0538328 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0534955 |
| TMSB4X | thymosin beta 4, X-linked | -0.0532997 |
| ENO1 | enolase 1, (alpha) | -0.0527821 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0513762 |
| RPS6 | ribosomal protein S6 | -0.0505277 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0501274 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0480737 |
| CALR | calreticulin | -0.0479817 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.047896 |
| THBS1 | thrombospondin 1 | -0.0474812 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0465923 |
| RPL23 | ribosomal protein L23 | -0.0463988 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0461142 |
| RASAL2 | RAS protein activator like 2 | -0.0457093 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0455356 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.044688 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0435702 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0434443 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0434247 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0433075 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.043161 |
| CBX3 | chromobox homolog 3 | -0.0428372 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0427563 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0426696 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0424781 |
| SYT1 | synaptotagmin I | -0.0424563 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0419366 |
| MAP4 | microtubule-associated protein 4 | -0.0418191 |
| EMP1 | epithelial membrane protein 1 | -0.0417835 |
| PCDH9 | protocadherin 9 | -0.0411857 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0409648 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0405579 |
| ZNF217 | zinc finger protein 217 | -0.0402865 |
| FTL | ferritin, light polypeptide | -0.040101 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0398702 |
| PCBP2 | poly(rC) binding protein 2 | -0.0396701 |
| LRRC4C | leucine rich repeat containing 4C | -0.0394784 |
| TCF12 | transcription factor 12 | -0.0394217 |
| POTEF | POTE ankyrin domain family, member F | -0.0394013 |
| TUBA1B | tubulin, alpha 1b | -0.0393026 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0392215 |
| UBC | ubiquitin C | -0.0391366 |
| SETD5 | SET domain containing 5 | -0.0389285 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0388958 |
| YBX1 | Y box binding protein 1 | -0.0388137 |
| CAVIN1 | caveolae associated protein 1 | -0.0385891 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0384277 |
| DST | dystonin | -0.0383371 |
| BBX | bobby sox homolog (Drosophila) | -0.0382937 |
| ACTG1 | actin gamma 1 | -0.0378518 |
| BPTF | bromodomain PHD finger transcription factor | -0.0378158 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0373459 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0373219 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0371775 |
| RAB31 | RAB31, member RAS oncogene family | -0.0371486 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0369524 |
| HDAC9 | histone deacetylase 9 | -0.0369427 |
| TMSB10 | thymosin beta 10 | -0.036722 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0365281 |
| FBL | fibrillarin | -0.0361481 |
| PHIP | pleckstrin homology domain interacting protein | -0.0359282 |
| CALU | calumenin | -0.0355589 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0354707 |
| GLG1 | golgi glycoprotein 1 | -0.0354592 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.035307 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0351801 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0351619 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0351165 |
| SEPTIN7 | septin 7 | -0.0350231 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0348641 |
| H1-0 | H1.0 linker histone | -0.0348552 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0345934 |
| RFPL4B | ret finger protein-like 4B | -0.0343706 |
| APP | amyloid beta (A4) precursor protein | -0.0340695 |
| WASF2 | WAS protein family, member 2 | -0.0338856 |