| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/79025 |
| Similar Terms | |
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198 proteins with high or low expression in D-(+)-Glucose relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KIAA0825 | KIAA0825 | 0.86 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.61 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.6 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.58 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 0.55 |
| ADCY10 | adenylate cyclase 10 (soluble) | 0.54 |
| MSX2 | msh homeobox 2 | 0.53 |
| SLC41A3 | solute carrier family 41, member 3 | 0.5 |
| SMAD1 | SMAD family member 1 | 0.49 |
| ZNF776 | zinc finger protein 776 | 0.48 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.46 |
| FAM117A | family with sequence similarity 117, member A | 0.46 |
| ZNF263 | zinc finger protein 263 | 0.46 |
| ATXN1L | ataxin 1-like | 0.43 |
| KLHL29 | kelch-like family member 29 | 0.42 |
| SDR16C5 | short chain dehydrogenase/reductase family 16C, member 5 | 0.38 |
| GSTZ1 | glutathione S-transferase zeta 1 | 0.38 |
| CPE | carboxypeptidase E | 0.35 |
| PLK4 | polo-like kinase 4 | 0.34 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.34 |
| ACTL8 | actin-like 8 | 0.34 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.33 |
| UNC13C | unc-13 homolog C (C. elegans) | 0.33 |
| HSH2D | hematopoietic SH2 domain containing | 0.33 |
| VIM | vimentin | 0.32 |
| PLXNB1 | plexin B1 | 0.31 |
| DIXDC1 | DIX domain containing 1 | 0.31 |
| GAS2L1 | growth arrest-specific 2 like 1 | 0.31 |
| METRN | meteorin, glial cell differentiation regulator | 0.31 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.3 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | 0.3 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | 0.3 |
| SHROOM1 | shroom family member 1 | 0.3 |
| DST | dystonin | 0.29 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | 0.29 |
| RGPD8 | RANBP2-like and GRIP domain containing 8 | 0.29 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.28 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.28 |
| ENTR1 | endosome associated trafficking regulator 1 | 0.28 |
| YDJC | YdjC homolog (bacterial) | 0.27 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.27 |
| ZGRF1 | zinc finger, GRF-type containing 1 | 0.27 |
| CUL9 | cullin 9 | 0.27 |
| ZG16B | zymogen granule protein 16B | 0.27 |
| ETV6 | ets variant 6 | 0.26 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.26 |
| DENND5A | DENN/MADD domain containing 5A | 0.26 |
| C6ORF136 | chromosome 6 open reading frame 136 | 0.26 |
| RILPL2 | Rab interacting lysosomal protein-like 2 | 0.25 |
| PEMT | phosphatidylethanolamine N-methyltransferase | 0.25 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.25 |
| RTL6 | retrotransposon Gag like 6 | 0.24 |
| TMEM175 | transmembrane protein 175 | 0.24 |
| GKAP1 | G kinase anchoring protein 1 | 0.24 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | 0.24 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.24 |
| TCEA3 | transcription elongation factor A (SII), 3 | 0.24 |
| ANKRD39 | ankyrin repeat domain 39 | 0.24 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.24 |
| LTO1 | LTO1 maturation factor of ABCE1 | 0.24 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | 0.24 |
| PEX16 | peroxisomal biogenesis factor 16 | 0.23 |
| COMMD2 | COMM domain containing 2 | 0.22 |
| ZNF200 | zinc finger protein 200 | 0.22 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 0.22 |
| MITD1 | MIT, microtubule interacting and transport, domain containing 1 | 0.22 |
| ATAD5 | ATPase family, AAA domain containing 5 | 0.22 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) | 0.22 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.22 |
| ELK1 | ELK1, member of ETS oncogene family | 0.22 |
| GRB14 | growth factor receptor-bound protein 14 | 0.21 |
| AMMECR1L | AMMECR1-like | 0.21 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.21 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.21 |
| GRK6 | G protein-coupled receptor kinase 6 | 0.21 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.21 |
| IFT22 | intraflagellar transport 22 | 0.21 |
| FABP6 | fatty acid binding protein 6, ileal | 0.21 |
| ZNF92 | zinc finger protein 92 | 0.21 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.21 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.21 |
| ZNF799 | zinc finger protein 799 | 0.21 |
| PDGFC | platelet derived growth factor C | 0.2 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.2 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | 0.2 |
| ZNF511 | zinc finger protein 511 | 0.2 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.2 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | 0.2 |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 | 0.2 |
| GPR108 | G protein-coupled receptor 108 | 0.2 |
| ANK2 | ankyrin 2, neuronal | 0.2 |
| E2F7 | E2F transcription factor 7 | 0.2 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.2 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | 0.2 |
| FBXO31 | F-box protein 31 | 0.2 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.2 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.19 |
| CCDC150 | coiled-coil domain containing 150 | 0.19 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.66 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.57 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) | -0.57 |
| FAM171A2 | family with sequence similarity 171, member A2 | -0.55 |
| HLA-F | major histocompatibility complex, class I, F | -0.51 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | -0.5 |
| SLC38A7 | solute carrier family 38, member 7 | -0.49 |
| SLC38A9 | solute carrier family 38, member 9 | -0.45 |
| TBC1D31 | TBC1 domain family, member 31 | -0.44 |
| ITGA1 | integrin, alpha 1 | -0.43 |
| NF1 | neurofibromin 1 | -0.41 |
| MRC2 | mannose receptor, C type 2 | -0.4 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 | -0.4 |
| CD82 | CD82 molecule | -0.4 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.4 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.38 |
| ALPK1 | alpha-kinase 1 | -0.38 |
| FAM219B | family with sequence similarity 219, member B | -0.38 |
| NIPSNAP3A | nipsnap homolog 3A (C. elegans) | -0.37 |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | -0.37 |
| TMSB10 | thymosin beta 10 | -0.35 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.34 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.34 |
| LRRC58 | leucine rich repeat containing 58 | -0.34 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.33 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | -0.33 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | -0.32 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.32 |
| PIP | prolactin-induced protein | -0.32 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.32 |
| ZNF189 | zinc finger protein 189 | -0.32 |
| ZBTB8A | zinc finger and BTB domain containing 8A | -0.31 |
| CTHRC1 | collagen triple helix repeat containing 1 | -0.31 |
| GUCD1 | guanylyl cyclase domain containing 1 | -0.31 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 | -0.31 |
| DUSP5 | dual specificity phosphatase 5 | -0.3 |
| ATE1 | arginyltransferase 1 | -0.3 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -0.29 |
| SGSH | N-sulfoglucosamine sulfohydrolase | -0.29 |
| S100A14 | S100 calcium binding protein A14 | -0.29 |
| MAP2 | microtubule-associated protein 2 | -0.29 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | -0.29 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.28 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -0.27 |
| CCNI | cyclin I | -0.27 |
| KLHDC8B | kelch domain containing 8B | -0.27 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.27 |
| UBL7 | ubiquitin-like 7 | -0.27 |
| C4BPA | complement component 4 binding protein, alpha | -0.27 |
| CCDC9B | coiled-coil domain containing 9B | -0.26 |
| ATXN7L1 | ataxin 7-like 1 | -0.26 |
| RPP21 | ribonuclease P/MRP 21kDa subunit | -0.26 |
| CDCA3 | cell division cycle associated 3 | -0.25 |
| ZFP36 | ZFP36 ring finger protein | -0.25 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.25 |
| MPV17 | MpV17 mitochondrial inner membrane protein | -0.25 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.25 |
| SERF2 | small EDRK-rich factor 2 | -0.25 |
| CEP112 | centrosomal protein 112kDa | -0.25 |
| ZBTB14 | zinc finger and BTB domain containing 14 | -0.25 |
| HBA1 | hemoglobin, alpha 1 | -0.25 |
| C19ORF25 | chromosome 19 open reading frame 25 | -0.24 |
| TMEM160 | transmembrane protein 160 | -0.24 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.24 |
| NPTXR | neuronal pentraxin receptor | -0.24 |
| DMXL2 | Dmx-like 2 | -0.24 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.24 |
| ADCK5 | aarF domain containing kinase 5 | -0.24 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.24 |
| TPM1 | tropomyosin 1 (alpha) | -0.24 |
| MED8 | mediator complex subunit 8 | -0.24 |
| BLOC1S5 | biogenesis of lysosomal organelles complex-1, subunit 5, muted | -0.24 |
| ICOSLG | inducible T-cell co-stimulator ligand | -0.23 |
| NMNAT3 | nicotinamide nucleotide adenylyltransferase 3 | -0.23 |
| RPAIN | RPA interacting protein | -0.23 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.23 |
| ISCA2 | iron-sulfur cluster assembly 2 | -0.23 |
| ATG2A | autophagy related 2A | -0.23 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | -0.23 |
| KCTD6 | potassium channel tetramerization domain containing 6 | -0.23 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.23 |
| DCLRE1C | DNA cross-link repair 1C | -0.23 |
| RTN1 | reticulon 1 | -0.22 |
| METTL26 | methyltransferase like 26 | -0.22 |
| PCNX1 | pecanex 1 | -0.22 |
| MCRIP1 | MAPK regulated corepressor interacting protein 1 | -0.22 |
| FBXO41 | F-box protein 41 | -0.22 |
| WDR20 | WD repeat domain 20 | -0.22 |
| PSEN1 | presenilin 1 | -0.22 |
| ADIRF | adipogenesis regulatory factor | -0.22 |
| METTL25 | methyltransferase like 25 | -0.22 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | -0.22 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.22 |
| BTBD11 | BTB (POZ) domain containing 11 | -0.22 |
| ZNF428 | zinc finger protein 428 | -0.21 |
| DENND4B | DENN/MADD domain containing 4B | -0.21 |
| ATG10 | autophagy related 10 | -0.21 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.21 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.21 |