D-423MG Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

249 genes mutated in the D-423MG cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ACSM4 acyl-CoA synthetase medium-chain family member 4
ACTRT2 actin-related protein T2
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADGRG1 adhesion G protein-coupled receptor G1
ADGRV1 adhesion G protein-coupled receptor V1
ADNP2 ADNP homeobox 2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AKAP9 A kinase (PRKA) anchor protein 9
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMBP alpha-1-microglobulin/bikunin precursor
ANAPC5 anaphase promoting complex subunit 5
ANKRD53 ankyrin repeat domain 53
ANXA10 annexin A10
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOB apolipoprotein B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBR apolipoprotein B receptor
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP32 Rho GTPase activating protein 32
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARNT aryl hydrocarbon receptor nuclear translocator
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASXL3 additional sex combs like transcriptional regulator 3
ATAD3C ATPase family, AAA domain containing 3C
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4
BCAR1 breast cancer anti-estrogen resistance 1
BPTF bromodomain PHD finger transcription factor
BSN bassoon presynaptic cytomatrix protein
CCDC144A coiled-coil domain containing 144A
CCDC15 coiled-coil domain containing 15
CCDC154 coiled-coil domain containing 154
CCDC33 coiled-coil domain containing 33
CCDC40 coiled-coil domain containing 40
CCDC67 coiled-coil domain containing 67
CD1C CD1c molecule
CD200 CD200 molecule
CDC73 cell division cycle 73
CDH19 cadherin 19, type 2
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CELF5 CUGBP, Elav-like family member 5
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CFAP57 cilia and flagella associated protein 57
CIITA class II, major histocompatibility complex, transactivator
CLDN9 claudin 9
CLTCL1 clathrin, heavy chain-like 1
CNOT10 CCR4-NOT transcription complex, subunit 10
COBL cordon-bleu WH2 repeat protein
COL4A1 collagen, type IV, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CRNKL1 crooked neck pre-mRNA splicing factor 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CYB5D2 cytochrome b5 domain containing 2
DAAM2 dishevelled associated activator of morphogenesis 2
DCC DCC netrin 1 receptor
DCHS2 dachsous cadherin-related 2
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DICER1 dicer 1, ribonuclease type III
DLC1 DLC1 Rho GTPase activating protein
DNAI1 dynein, axonemal, intermediate chain 1
DOK5 docking protein 5
DTX2 deltex 2, E3 ubiquitin ligase
DUSP26 dual specificity phosphatase 26 (putative)
E4F1 E4F transcription factor 1
ECEL1 endothelin converting enzyme-like 1
EFCAB6 EF-hand calcium binding domain 6
EFHB EF-hand domain family, member B
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EML6 echinoderm microtubule associated protein like 6
ESYT2 extended synaptotagmin-like protein 2
EVX2 even-skipped homeobox 2
EWSR1 EWS RNA-binding protein 1
FAM63A family with sequence similarity 63, member A
FAM92B family with sequence similarity 92, member B
FCF1 FCF1 rRNA-processing protein
FCGBP Fc fragment of IgG binding protein
FIG4 FIG4 phosphoinositide 5-phosphatase
FREM1 FRAS1 related extracellular matrix 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GBP6 guanylate binding protein family, member 6
GJB5 gap junction protein, beta 5, 31.1kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPC4 glypican 4
GYG1 glycogenin 1
HDAC4 histone deacetylase 4
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HHAT hedgehog acyltransferase
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HRNR hornerin
IFT57 intraflagellar transport 57
IQGAP2 IQ motif containing GTPase activating protein 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KDM6A lysine (K)-specific demethylase 6A
KIAA1109 KIAA1109
KIAA1671 KIAA1671
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHDC1 kelch domain containing 1
KLHL40 kelch-like family member 40
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
L3MBTL4 l(3)mbt-like 4 (Drosophila)
LDHA lactate dehydrogenase A
LIN7C lin-7 homolog C (C. elegans)
LRGUK leucine-rich repeats and guanylate kinase domain containing
LRRC45 leucine rich repeat containing 45
MACF1 microtubule-actin crosslinking factor 1
MAP1A microtubule-associated protein 1A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAST4 microtubule associated serine/threonine kinase family member 4
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MEMO1 mediator of cell motility 1
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLKL mixed lineage kinase domain-like
MON1A MON1 secretory trafficking family member A
MPL MPL proto-oncogene, thrombopoietin receptor
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUM1 melanoma associated antigen (mutated) 1
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NBPF10 neuroblastoma breakpoint family, member 10
NCOR1 nuclear receptor corepressor 1
NEK11 NIMA-related kinase 11
NID2 nidogen 2 (osteonidogen)
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRXN1 neurexin 1
OIT3 oncoprotein induced transcript 3
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR5M9 olfactory receptor, family 5, subfamily M, member 9
OTOL1 otolin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHGA8 protocadherin gamma subfamily A, 8
PCLO piccolo presynaptic cytomatrix protein
PDC phosducin
PDS5B PDS5 cohesin associated factor B
PGK1 phosphoglycerate kinase 1
PIH1D2 PIH1 domain containing 2
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PKD1L1 polycystic kidney disease 1 like 1
PLAT plasminogen activator, tissue
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLXNA2 plexin A2
PLXNB3 plexin B3
PNPLA5 patatin-like phospholipase domain containing 5
POGZ pogo transposable element with ZNF domain
POM121L2 POM121 transmembrane nucleoporin-like 2
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRAMEF2 PRAME family member 2
PRDM8 PR domain containing 8
PRDM9 PR domain containing 9
PRMT5 protein arginine methyltransferase 5
PRR14 proline rich 14
PTEN phosphatase and tensin homolog
PTK6 protein tyrosine kinase 6
PTPRT protein tyrosine phosphatase, receptor type, T
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RABAC1 Rab acceptor 1 (prenylated)
RAD21 RAD21 homolog (S. pombe)
RBM15B RNA binding motif protein 15B
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGPD1 RANBP2-like and GRIP domain containing 1
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RHPN2 rhophilin, Rho GTPase binding protein 2
RIN2 Ras and Rab interactor 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RRBP1 ribosome binding protein 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUFY4 RUN and FYVE domain containing 4
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
S100A1 S100 calcium binding protein A1
SAMD10 sterile alpha motif domain containing 10
SAMD4B sterile alpha motif domain containing 4B
SAMHD1 SAM domain and HD domain 1
SARS seryl-tRNA synthetase
SCGB1D2 secretoglobin, family 1D, member 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEPT9 septin 9
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGK223 homolog of rat pragma of Rnd2
SHISA7 shisa family member 7
SLC25A45 solute carrier family 25, member 45
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLITRK6 SLIT and NTRK-like family, member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNX18 sorting nexin 18
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPATA31A6 SPATA31 subfamily A, member 6
SPATA5 spermatogenesis associated 5
ST18 suppression of tumorigenicity 18, zinc finger
STARD13 StAR-related lipid transfer (START) domain containing 13
SVIL supervillin
TBC1D15 TBC1 domain family, member 15
TBK1 TANK-binding kinase 1
TCTN1 tectonic family member 1
TENM1 teneurin transmembrane protein 1
TGS1 trimethylguanosine synthase 1
THAP1 THAP domain containing, apoptosis associated protein 1
TLK1 tousled-like kinase 1
TMEM145 transmembrane protein 145
TMEM175 transmembrane protein 175
TMEM208 transmembrane protein 208
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIM50 tripartite motif containing 50
TRIM6 tripartite motif containing 6
TTF2 transcription termination factor, RNA polymerase II
UBE2C ubiquitin-conjugating enzyme E2C
UBE4A ubiquitination factor E4A
UFSP1 UFM1-specific peptidase 1 (non-functional)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VMP1 vacuole membrane protein 1
WFS1 Wolfram syndrome 1 (wolframin)
WSCD1 WSC domain containing 1
XKR3 XK, Kell blood group complex subunit-related family, member 3
XYLT1 xylosyltransferase I
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC16 zinc finger, CCHC domain containing 16
ZMYND8 zinc finger, MYND-type containing 8
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF324B zinc finger protein 324B
ZNF563 zinc finger protein 563
ZNF644 zinc finger protein 644
ZNF679 zinc finger protein 679
ZNF683 zinc finger protein 683
ZNF81 zinc finger protein 81
ZNF831 zinc finger protein 831
ZNF839 zinc finger protein 839
ZNF846 zinc finger protein 846
ZSCAN22 zinc finger and SCAN domain containing 22