D-423MG Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

305 genes with high or low expression in D-423MG relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
TSFM Ts translation elongation factor, mitochondrial 3.60177
METTL1 methyltransferase like 1 3.59955
COL8A1 collagen, type VIII, alpha 1 2.9332
CDK4 cyclin-dependent kinase 4 2.67014
METTL21B methyltransferase like 21B 2.62736
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.62719
WISP1 WNT1 inducible signaling pathway protein 1 2.61173
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.59607
TSPAN31 tetraspanin 31 2.55856
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.51762
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.51102
DPT dermatopontin 2.49686
CH25H cholesterol 25-hydroxylase 2.4616
FKBP14 FK506 binding protein 14, 22 kDa 2.43308
CXCL13 chemokine (C-X-C motif) ligand 13 2.4017
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.35753
PCDHB12 protocadherin beta 12 2.32197
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.30374
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2.28032
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.24294
UBL5 ubiquitin-like 5 2.20659
BSG basigin (Ok blood group) 2.17382
IMPAD1 inositol monophosphatase domain containing 1 2.15094
P3H1 prolyl 3-hydroxylase 1 2.14464
CA9 carbonic anhydrase IX 2.13287
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 2.09249
CABP1 calcium binding protein 1 2.07229
EIF3I eukaryotic translation initiation factor 3, subunit I 2.06117
EDIL3 EGF-like repeats and discoidin I-like domains 3 2.05574
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.03844
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.03623
DTX3 deltex 3, E3 ubiquitin ligase 2.01826
DCN decorin 2.00845
MRPL17 mitochondrial ribosomal protein L17 1.94244
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.93011
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.90765
PDAP1 PDGFA associated protein 1 1.89494
TMEM45A transmembrane protein 45A 1.89455
RCN3 reticulocalbin 3, EF-hand calcium binding domain 1.85564
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 1.84638
EPYC epiphycan 1.82986
GLT8D2 glycosyltransferase 8 domain containing 2 1.8169
EMC1 ER membrane protein complex subunit 1 1.81509
RARS arginyl-tRNA synthetase 1.79058
GEMIN6 gem (nuclear organelle) associated protein 6 1.78016
SLC26A10 solute carrier family 26, member 10 1.77505
PCDHB13 protocadherin beta 13 1.75932
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.74934
MAGEC2 melanoma antigen family C2 1.74714
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 1.73973
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.7338
GREM1 gremlin 1, DAN family BMP antagonist 1.71926
ANGPT1 angiopoietin 1 1.71812
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.71559
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 1.70215
SSX2 synovial sarcoma, X breakpoint 2 1.68222
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.6789
SEC61G Sec61 gamma subunit 1.67129
SPANXC SPANX family, member C 1.66665
ANTXR1 anthrax toxin receptor 1 1.66536
PCDHB11 protocadherin beta 11 1.6591
HAB1 B1 for mucin 1.63578
EIF5A eukaryotic translation initiation factor 5A 1.62214
PTGFR prostaglandin F receptor (FP) 1.6209
AVIL advillin 1.61075
CDH9 cadherin 9, type 2 (T1-cadherin) 1.60473
PDIA4 protein disulfide isomerase family A, member 4 1.58958
ZSCAN5A zinc finger and SCAN domain containing 5A 1.57815
COL6A3 collagen, type VI, alpha 3 1.57747
COL1A1 collagen, type I, alpha 1 1.57436
ADGRE1 adhesion G protein-coupled receptor E1 1.57427
PRDX4 peroxiredoxin 4 1.56893
LRRC15 leucine rich repeat containing 15 1.56359
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.55671
PAM peptidylglycine alpha-amidating monooxygenase 1.54524
DERL2 derlin 2 1.53323
DRG2 developmentally regulated GTP binding protein 2 1.53131
PI15 peptidase inhibitor 15 1.52763
DIRAS3 DIRAS family, GTP-binding RAS-like 3 1.5237
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.52088
PCDHB3 protocadherin beta 3 1.52045
TUBA3C tubulin, alpha 3c 1.5202
LUM lumican 1.51541
COL3A1 collagen, type III, alpha 1 1.50667
PCOLCE procollagen C-endopeptidase enhancer 1.50285
RPA3 replication protein A3, 14kDa 1.49873
MPDU1 mannose-P-dolichol utilization defect 1 1.49663
KCNK2 potassium channel, two pore domain subfamily K, member 2 1.49502
ZNF20 zinc finger protein 20 1.49282
PRAF2 PRA1 domain family, member 2 1.49241
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.48668
YIPF5 Yip1 domain family, member 5 1.48462
ZNF550 zinc finger protein 550 1.48292
LAMA2 laminin, alpha 2 1.48006
SPAG4 sperm associated antigen 4 1.46963
VEGFC vascular endothelial growth factor C 1.46957
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 1.46439
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.46211
HCCS holocytochrome c synthase 1.46129
TGFBR1 transforming growth factor, beta receptor 1 1.45176
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 1.45135
CFAP44 cilia and flagella associated protein 44 1.44466
SULF1 sulfatase 1 1.43782
MMP13 matrix metallopeptidase 13 1.43547
OLFML2B olfactomedin-like 2B 1.43533
MANF mesencephalic astrocyte-derived neurotrophic factor 1.43439
MAGEA8 melanoma antigen family A8 1.43163
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.42457

low expression

Symbol Name Standardized Value
ENO1 enolase 1, (alpha) -3.53725
VAMP3 vesicle-associated membrane protein 3 -3.53718
PCDH11Y protocadherin 11 Y-linked -3.12637
RERE arginine-glutamic acid dipeptide (RE) repeats -3.10468
CD180 CD180 molecule -3.0873
PARK7 parkinson protein 7 -3.07708
CDH5 cadherin 5, type 2 (vascular endothelium) -2.84093
SLC17A4 solute carrier family 17, member 4 -2.76997
MBNL3 muscleblind-like splicing regulator 3 -2.68658
EPS15P1 epidermal growth factor receptor pathway substrate 15 pseudogene 1 -2.63459
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -2.61385
IRS4 insulin receptor substrate 4 -2.58824
DICER1 dicer 1, ribonuclease type III -2.53715
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.52408
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -2.50018
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.46149
PDGFRL platelet-derived growth factor receptor-like -2.42569
SYT12 synaptotagmin XII -2.40429
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -2.33819
STEAP4 STEAP family member 4 -2.33698
BIK BCL2-interacting killer (apoptosis-inducing) -2.29892
PTER phosphotriesterase related -2.22028
MSLN mesothelin -2.19791
NBEAL2 neurobeachin-like 2 -2.19575
NCR1 natural cytotoxicity triggering receptor 1 -2.19137
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 -2.18938
ELN elastin -2.15647
MYF6 myogenic factor 6 (herculin) -2.14041
ROM1 retinal outer segment membrane protein 1 -2.13775
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -2.13704
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -2.13525
DDN dendrin -2.10944
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.10567
MMRN1 multimerin 1 -2.09842
SP2 Sp2 transcription factor -2.08106
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -2.04978
DIDO1 death inducer-obliterator 1 -2.04404
USF2 upstream transcription factor 2, c-fos interacting -2.03893
OBP2A odorant binding protein 2A -2.0118
CLEC7A C-type lectin domain family 7, member A -2.0117
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene -2.00162
CRYBB1 crystallin, beta B1 -1.99972
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -1.98743
LTBP4 latent transforming growth factor beta binding protein 4 -1.98039
C6 complement component 6 -1.97165
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -1.97129
GAL galanin/GMAP prepropeptide -1.96889
ZNF106 zinc finger protein 106 -1.96711
HDAC11 histone deacetylase 11 -1.96546
THSD4 thrombospondin, type I, domain containing 4 -1.96351
FRMPD1 FERM and PDZ domain containing 1 -1.95502
LPAR3 lysophosphatidic acid receptor 3 -1.95236
NR1I2 nuclear receptor subfamily 1, group I, member 2 -1.95103
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 -1.95035
TEC tec protein tyrosine kinase -1.94248
RAD23A RAD23 homolog A (S. cerevisiae) -1.94008
ALPP alkaline phosphatase, placental -1.93568
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -1.92216
HAGH hydroxyacylglutathione hydrolase -1.92118
PRDM11 PR domain containing 11 -1.91823
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A -1.90194
HOXA2 homeobox A2 -1.90099
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.90068
UPB1 ureidopropionase, beta -1.89797
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) -1.89177
MOG myelin oligodendrocyte glycoprotein -1.88722
RGS6 regulator of G-protein signaling 6 -1.88274
CHIA chitinase, acidic -1.87028
LRRK1 leucine-rich repeat kinase 1 -1.86167
RBM38 RNA binding motif protein 38 -1.85233
ZNF282 zinc finger protein 282 -1.84548
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -1.84362
DENND1C DENN/MADD domain containing 1C -1.84197
MTNR1A melatonin receptor 1A -1.83864
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -1.83273
SLIT3 slit homolog 3 (Drosophila) -1.82063
SORBS1 sorbin and SH3 domain containing 1 -1.81634
AMPD1 adenosine monophosphate deaminase 1 -1.81227
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled -1.81059
NUPL1 nucleoporin like 1 -1.79875
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -1.79492
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -1.79387
CHAD chondroadherin -1.79253
SNCB synuclein, beta -1.78626
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -1.78594
VAX2 ventral anterior homeobox 2 -1.78378
OR1A2 olfactory receptor, family 1, subfamily A, member 2 -1.77414
SPPL2B signal peptide peptidase like 2B -1.76038
AKR1C4 aldo-keto reductase family 1, member C4 -1.75448
SIAH1 siah E3 ubiquitin protein ligase 1 -1.72829
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta -1.72602
ABLIM2 actin binding LIM protein family, member 2 -1.70614
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding) -1.70267
WAS Wiskott-Aldrich syndrome -1.70146
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -1.69713
GIGYF2 GRB10 interacting GYF protein 2 -1.69471
CNGA1 cyclic nucleotide gated channel alpha 1 -1.69327
CD6 CD6 molecule -1.69271
PBX2 pre-B-cell leukemia homeobox 2 -1.69085
GZMM granzyme M (lymphocyte met-ase 1) -1.68849
GRM5 glutamate receptor, metabotropic 5 -1.68393
BPI bactericidal/permeability-increasing protein -1.68239
ETV4 ets variant 4 -1.68149
EFCC1 EF-hand and coiled-coil domain containing 1 -1.68017
FRK fyn-related Src family tyrosine kinase -1.67914
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 -1.67532
ADM2 adrenomedullin 2 -1.67526
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -1.67144
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -1.66656
GPI glucose-6-phosphate isomerase -1.6635
MRPL2 mitochondrial ribosomal protein L2 -1.66139
ZSCAN16 zinc finger and SCAN domain containing 16 -1.66077
DEFB126 defensin, beta 126 -1.65842
BCR breakpoint cluster region -1.65757
RIMBP2 RIMS binding protein 2 -1.65442
GFRA1 GDNF family receptor alpha 1 -1.64497
APOF apolipoprotein F -1.63763
TRAF1 TNF receptor-associated factor 1 -1.6263
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 -1.62032
LY6D lymphocyte antigen 6 complex, locus D -1.61836
KTN1 kinectin 1 (kinesin receptor) -1.61404
NELFA negative elongation factor complex member A -1.61038
LOC202181 SUMO-interacting motifs containing 1 pseudogene -1.60456
LAMB4 laminin, beta 4 -1.6042
HHCM Mahlavu hepatocellular carcinoma -1.59982
GALT galactose-1-phosphate uridylyltransferase -1.59402
CLDN1 claudin 1 -1.58916
SECISBP2 SECIS binding protein 2 -1.58725
KLHL4 kelch-like family member 4 -1.58517
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa -1.58105
PCDH1 protocadherin 1 -1.57574
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -1.57548
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -1.57495
MRPS18B mitochondrial ribosomal protein S18B -1.57113
OR51E2 olfactory receptor, family 51, subfamily E, member 2 -1.56829
ICE2 interactor of little elongation complex ELL subunit 2 -1.56593
PHOX2A paired-like homeobox 2a -1.56506
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase -1.55925
FAM50B family with sequence similarity 50, member B -1.5589
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -1.55469
PBOV1 prostate and breast cancer overexpressed 1 -1.55469
CALCRL calcitonin receptor-like -1.55365
ZBTB7A zinc finger and BTB domain containing 7A -1.54812
CELA2A chymotrypsin-like elastase family, member 2A -1.54801
BTNL2 butyrophilin-like 2 -1.54758
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) -1.54731
LAG3 lymphocyte-activation gene 3 -1.54677
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -1.54605
ZNF695 zinc finger protein 695 -1.54516
SH3BP2 SH3-domain binding protein 2 -1.53876
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D -1.53636
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -1.53513
KIAA0195 KIAA0195 -1.53243
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -1.51938
IFNA6 interferon, alpha 6 -1.51619
UBAP2 ubiquitin associated protein 2 -1.51529
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 -1.5098
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.50574
NOTCH4 notch 4 -1.50527
CDX2 caudal type homeobox 2 -1.50416
XPA xeroderma pigmentosum, complementation group A -1.50102
NPDC1 neural proliferation, differentiation and control, 1 -1.49603
BSPRY B-box and SPRY domain containing -1.49507
SYNE2 spectrin repeat containing, nuclear envelope 2 -1.4941
PKLR pyruvate kinase, liver and RBC -1.49196
FGF21 fibroblast growth factor 21 -1.48536
ASPA aspartoacylase -1.48445
MYL7 myosin, light chain 7, regulatory -1.48353
JAK3 Janus kinase 3 -1.48275
GALR1 galanin receptor 1 -1.48015
CA1 carbonic anhydrase I -1.47932
ASGR2 asialoglycoprotein receptor 2 -1.4788
PRSS3P2 protease, serine, 3 pseudogene 2 -1.4746
ARPP19 cAMP-regulated phosphoprotein, 19kDa -1.47058
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -1.46762
MYNN myoneurin -1.46564
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.46204
WNT7A wingless-type MMTV integration site family, member 7A -1.45826
ZBTB3 zinc finger and BTB domain containing 3 -1.45796
CD5 CD5 molecule -1.45631
DIAPH2-AS1 DIAPH2 antisense RNA 1 -1.45316
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -1.45289
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene -1.45151
GBX2 gastrulation brain homeobox 2 -1.44481
ADGRG1 adhesion G protein-coupled receptor G1 -1.44457
KLF8 Kruppel-like factor 8 -1.44454
JUND jun D proto-oncogene -1.44328
SPAST spastin -1.44218
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) -1.44139
ZFP2 ZFP2 zinc finger protein -1.43329
NR4A1 nuclear receptor subfamily 4, group A, member 1 -1.43231
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -1.42888
GJB5 gap junction protein, beta 5, 31.1kDa -1.42623
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -1.42468
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -1.42286
SH3GLB2 SH3-domain GRB2-like endophilin B2 -1.4205
SIRT6 sirtuin 6 -1.41812