D-502MG Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

300 genes with high or low expression in D-502MG relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 3.60177
KCTD9 potassium channel tetramerization domain containing 9 3.55329
GRIA1 glutamate receptor, ionotropic, AMPA 1 3.07295
ADARB1 adenosine deaminase, RNA-specific, B1 3.03452
OGDHL oxoglutarate dehydrogenase-like 2.88025
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.8532
NF2 neurofibromin 2 (merlin) 2.69436
SOX3 SRY (sex determining region Y)-box 3 2.66778
FNDC4 fibronectin type III domain containing 4 2.64402
DNMBP dynamin binding protein 2.53054
TOM1L2 target of myb1-like 2 (chicken) 2.52686
NRCAM neuronal cell adhesion molecule 2.47952
CEND1 cell cycle exit and neuronal differentiation 1 2.47339
MCHR1 melanin-concentrating hormone receptor 1 2.44618
NLRP1 NLR family, pyrin domain containing 1 2.4326
ELOVL6 ELOVL fatty acid elongase 6 2.38153
PREP prolyl endopeptidase 2.34757
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.30726
SIK2 salt-inducible kinase 2 2.29683
TRIM45 tripartite motif containing 45 2.29279
CDH4 cadherin 4, type 1, R-cadherin (retinal) 2.28683
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2.2682
CNR1 cannabinoid receptor 1 (brain) 2.24572
STAMBP STAM binding protein 2.2437
PRDX6 peroxiredoxin 6 2.23959
EML1 echinoderm microtubule associated protein like 1 2.19096
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.18648
EGF epidermal growth factor 2.15652
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.15386
FLG filaggrin 2.15159
MFGE8 milk fat globule-EGF factor 8 protein 2.14548
EFNB2 ephrin-B2 2.12744
PTCH2 patched 2 2.12557
METRN meteorin, glial cell differentiation regulator 2.12096
HOXD12 homeobox D12 2.10157
SYNJ2 synaptojanin 2 2.09743
TMEM9B TMEM9 domain family, member B 2.09697
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 2.09106
SORBS2 sorbin and SH3 domain containing 2 2.07599
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 2.03593
LGI1 leucine-rich, glioma inactivated 1 2.01592
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.00958
PEPD peptidase D 2.00305
BICD1 bicaudal D homolog 1 (Drosophila) 1.97871
CDO1 cysteine dioxygenase type 1 1.94945
EEA1 early endosome antigen 1 1.94648
GTF2H5 general transcription factor IIH, polypeptide 5 1.94033
LYPD1 LY6/PLAUR domain containing 1 1.91864
USP46 ubiquitin specific peptidase 46 1.91494
ENDOD1 endonuclease domain containing 1 1.91067
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 1.90635
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 1.89639
TMOD1 tropomodulin 1 1.89414
MFAP5 microfibrillar associated protein 5 1.88212
PTPN9 protein tyrosine phosphatase, non-receptor type 9 1.87982
GAP43 growth associated protein 43 1.87817
GFAP glial fibrillary acidic protein 1.86913
PROP1 PROP paired-like homeobox 1 1.8561
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 1.84518
FABP7 fatty acid binding protein 7, brain 1.8432
MTCL1 microtubule crosslinking factor 1 1.84312
TMEM100 transmembrane protein 100 1.83622
SCUBE2 signal peptide, CUB domain, EGF-like 2 1.82811
RBP1 retinol binding protein 1, cellular 1.80919
MALT1 MALT1 paracaspase 1.79949
TACC1 transforming, acidic coiled-coil containing protein 1 1.79593
COL4A6 collagen, type IV, alpha 6 1.79417
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.79333
CRAT carnitine O-acetyltransferase 1.79187
PSPH phosphoserine phosphatase 1.77122
SEC14L2 SEC14-like 2 (S. cerevisiae) 1.76598
KLHDC8A kelch domain containing 8A 1.75192
PEX14 peroxisomal biogenesis factor 14 1.74954
SCD5 stearoyl-CoA desaturase 5 1.74613
SEPT2 septin 2 1.74422
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.73438
LALBA lactalbumin, alpha- 1.72437
KLHL20 kelch-like family member 20 1.72081
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.70819
CSRP2 cysteine and glycine-rich protein 2 1.69748
LRRC2 leucine rich repeat containing 2 1.69416
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.68717
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.68506
CD34 CD34 molecule 1.67954
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.67599
CNIH3 cornichon family AMPA receptor auxiliary protein 3 1.66707
RAB31 RAB31, member RAS oncogene family 1.66651
CSDC2 cold shock domain containing C2, RNA binding 1.65596
FZD1 frizzled class receptor 1 1.64962
ZNF365 zinc finger protein 365 1.64838
DIRAS3 DIRAS family, GTP-binding RAS-like 3 1.64821
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 1.64762
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.63027
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 1.62647
WEE1 WEE1 G2 checkpoint kinase 1.62383
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.62239
AP4M1 adaptor-related protein complex 4, mu 1 subunit 1.61663
FOXD1 forkhead box D1 1.61647
RAB40B RAB40B, member RAS oncogene family 1.61265
DIABLO diablo, IAP-binding mitochondrial protein 1.61114
SH3BP4 SH3-domain binding protein 4 1.60647
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.58463
SCARA3 scavenger receptor class A, member 3 1.57735
SOD3 superoxide dismutase 3, extracellular 1.56705
SEC14L1 SEC14-like 1 (S. cerevisiae) 1.56191
TEX2 testis expressed 2 1.55809
ECE2 endothelin converting enzyme 2 1.55611
MACF1 microtubule-actin crosslinking factor 1 1.55337
PMEPA1 prostate transmembrane protein, androgen induced 1 1.55181
NES nestin 1.5514
SORBS1 sorbin and SH3 domain containing 1 1.54991
PRKCQ protein kinase C, theta 1.54881
VAX2 ventral anterior homeobox 2 1.54859
MYH9 myosin, heavy chain 9, non-muscle 1.54626
RYR3 ryanodine receptor 3 1.54589
HOMER2 homer scaffolding protein 2 1.54112
MEIS2 Meis homeobox 2 1.52688
OPCML opioid binding protein/cell adhesion molecule-like 1.52049
KIAA0754 KIAA0754 1.52
HDAC3 histone deacetylase 3 1.51681
SCG2 secretogranin II 1.50591
DUX1 double homeobox 1 1.50569
PGC progastricsin (pepsinogen C) 1.50067
GPM6B glycoprotein M6B 1.4918
GPC4 glypican 4 1.4916
SFRP4 secreted frizzled-related protein 4 1.4876
ARSF arylsulfatase F 1.48236
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.48191
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 1.48123
PIPOX pipecolic acid oxidase 1.47949
CXCL14 chemokine (C-X-C motif) ligand 14 1.47941
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.47684
ANXA2P3 annexin A2 pseudogene 3 1.47508
NBEA neurobeachin 1.46999
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.45408
SCHIP1 schwannomin interacting protein 1 1.43374
MXRA7 matrix-remodelling associated 7 1.43367
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 1.43315
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.42705
SOX5 SRY (sex determining region Y)-box 5 1.42496
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 1.42417
FBXO21 F-box protein 21 1.42287
PTN pleiotrophin 1.42162
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.41822

low expression

Symbol Name Standardized Value
SNHG3 small nucleolar RNA host gene 3 -3.42002
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -3.37457
HIST1H2BI histone cluster 1, H2bi -3.17856
DCAF13 DDB1 and CUL4 associated factor 13 -3.09616
CRHR2 corticotropin releasing hormone receptor 2 -2.83362
HIST1H2BF histone cluster 1, H2bf -2.8181
PARK7 parkinson protein 7 -2.64394
RERE arginine-glutamic acid dipeptide (RE) repeats -2.6356
TLK2 tousled-like kinase 2 -2.60121
VAMP3 vesicle-associated membrane protein 3 -2.60116
PPID peptidylprolyl isomerase D -2.59197
AATF apoptosis antagonizing transcription factor -2.58207
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 -2.50395
LRPPRC leucine-rich pentatricopeptide repeat containing -2.47049
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -2.46104
PFDN6 prefoldin subunit 6 -2.35086
NCBP1 nuclear cap binding protein subunit 1, 80kDa -2.31753
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -2.31753
CXXC4 CXXC finger protein 4 -2.28204
KLHL29 kelch-like family member 29 -2.27414
ZNF185 zinc finger protein 185 (LIM domain) -2.27184
COL11A2 collagen, type XI, alpha 2 -2.26879
CELA2A chymotrypsin-like elastase family, member 2A -2.19353
DPH2 DPH2 homolog (S. cerevisiae) -2.17842
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -2.17348
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.17335
LHX1 LIM homeobox 1 -2.17122
GRTP1 growth hormone regulated TBC protein 1 -2.13725
DDIT4 DNA-damage-inducible transcript 4 -2.12951
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.11878
EXOSC5 exosome component 5 -2.10197
PER3 period circadian clock 3 -2.09416
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.08885
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -2.07736
MTIF2 mitochondrial translational initiation factor 2 -2.07467
CDON cell adhesion associated, oncogene regulated -2.06043
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -2.04942
FZD6 frizzled class receptor 6 -2.04835
ZNF281 zinc finger protein 281 -2.03673
KRT9 keratin 9, type I -2.02964
TBC1D4 TBC1 domain family, member 4 -1.98622
TBRG4 transforming growth factor beta regulator 4 -1.97422
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -1.95082
CLMN calmin (calponin-like, transmembrane) -1.93186
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -1.91325
HNF1B HNF1 homeobox B -1.91295
MYLIP myosin regulatory light chain interacting protein -1.91272
HDAC5 histone deacetylase 5 -1.90952
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -1.90946
DPYS dihydropyrimidinase -1.90407
GLCE glucuronic acid epimerase -1.90249
FLJ21369 uncharacterized protein FLJ21369 -1.87413
IL1R1 interleukin 1 receptor, type I -1.86592
MTUS1 microtubule associated tumor suppressor 1 -1.86315
MED26 mediator complex subunit 26 -1.84131
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -1.83219
HOXA3 homeobox A3 -1.80474
FKBP5 FK506 binding protein 5 -1.78993
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -1.78508
KLF1 Kruppel-like factor 1 (erythroid) -1.77391
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 -1.77
NFYA nuclear transcription factor Y, alpha -1.76631
TNS1 tensin 1 -1.75401
MYBBP1A MYB binding protein (P160) 1a -1.75324
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -1.7429
PTPRO protein tyrosine phosphatase, receptor type, O -1.73817
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.73815
DSC3 desmocollin 3 -1.73741
EIF1 eukaryotic translation initiation factor 1 -1.73684
POMT2 protein-O-mannosyltransferase 2 -1.73119
ARID5A AT rich interactive domain 5A (MRF1-like) -1.72897
PREB prolactin regulatory element binding -1.72322
ONECUT1 one cut homeobox 1 -1.72005
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -1.71308
RSL1D1 ribosomal L1 domain containing 1 -1.71205
MYOZ1 myozenin 1 -1.70333
ABT1 activator of basal transcription 1 -1.68577
GMPR guanosine monophosphate reductase -1.66322
NPHP4 nephronophthisis 4 -1.66287
CBX4 chromobox homolog 4 -1.65349
EPHB3 EPH receptor B3 -1.64899
PLAA phospholipase A2-activating protein -1.64566
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -1.64556
GSTA3 glutathione S-transferase alpha 3 -1.64516
RGS1 regulator of G-protein signaling 1 -1.63096
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase -1.62751
KRT83 keratin 83, type II -1.62653
QPCTL glutaminyl-peptide cyclotransferase-like -1.62559
NR2F2 nuclear receptor subfamily 2, group F, member 2 -1.62521
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.62259
LINC00312 long intergenic non-protein coding RNA 312 -1.61486
PRDM2 PR domain containing 2, with ZNF domain -1.61386
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 -1.61361
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -1.61324
AIM2 absent in melanoma 2 -1.60826
KPNA5 karyopherin alpha 5 (importin alpha 6) -1.60789
NRIP2 nuclear receptor interacting protein 2 -1.60422
CRLF1 cytokine receptor-like factor 1 -1.60257
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -1.60133
PIP prolactin-induced protein -1.59812
DTWD1 DTW domain containing 1 -1.59437
GPATCH3 G patch domain containing 3 -1.59055
SOCS1 suppressor of cytokine signaling 1 -1.58729
GP6 glycoprotein VI (platelet) -1.57107
PLCB4 phospholipase C, beta 4 -1.56878
ZIM2 zinc finger, imprinted 2 -1.56637
RNGTT RNA guanylyltransferase and 5'-phosphatase -1.56416
TGFBR3 transforming growth factor, beta receptor III -1.56401
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 -1.56334
LRRC6 leucine rich repeat containing 6 -1.55161
MKRN2 makorin ring finger protein 2 -1.54612
VRK2 vaccinia related kinase 2 -1.54293
EDN3 endothelin 3 -1.54171
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 -1.53879
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -1.53675
ADRA2C adrenoceptor alpha 2C -1.53405
SLC30A4 solute carrier family 30 (zinc transporter), member 4 -1.52583
VEGFA vascular endothelial growth factor A -1.52306
GCLC glutamate-cysteine ligase, catalytic subunit -1.5209
SDAD1 SDA1 domain containing 1 -1.51694
THADA thyroid adenoma associated -1.51259
HIST1H4D histone cluster 1, H4d -1.50582
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 -1.50374
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -1.50034
HIST1H3I histone cluster 1, H3i -1.50028
SIRAL2 SIR2 antiphage like 2 -1.49664
DENND1C DENN/MADD domain containing 1C -1.4916
FGF22 fibroblast growth factor 22 -1.49124
GAS7 growth arrest-specific 7 -1.49114
BASP1 brain abundant, membrane attached signal protein 1 -1.49074
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 -1.48795
TONSL tonsoku-like, DNA repair protein -1.48575
IFT74 intraflagellar transport 74 -1.48276
C2CD2L C2CD2-like -1.48229
SCGN secretagogin, EF-hand calcium binding protein -1.47982
ZNF652 zinc finger protein 652 -1.47392
SIX2 SIX homeobox 2 -1.47356
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -1.47107
SPTBN2 spectrin, beta, non-erythrocytic 2 -1.46848
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -1.46839
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -1.46477
PARP8 poly (ADP-ribose) polymerase family, member 8 -1.46147
SERTAD2 SERTA domain containing 2 -1.46077
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -1.45854
HIST1H2BH histone cluster 1, H2bh -1.45146
IL36G interleukin 36, gamma -1.44759
DHPS deoxyhypusine synthase -1.44513
MTF2 metal response element binding transcription factor 2 -1.4401
RPA2 replication protein A2, 32kDa -1.435
HOXC11 homeobox C11 -1.43017
NELL2 NEL-like 2 (chicken) -1.42497
TG thyroglobulin -1.42445
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.42333
NLE1 notchless homolog 1 (Drosophila) -1.42143
SMG7-AS1 SMG7 antisense RNA 1 -1.41973
ZNHIT3 zinc finger, HIT-type containing 3 -1.41896