D-566MG Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

212 genes mutated in the D-566MG cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADCY7 adenylate cyclase 7
ADGRG4 adhesion G protein-coupled receptor G4
ADTRP androgen-dependent TFPI-regulating protein
AFF3 AF4/FMR2 family, member 3
AJUBA ajuba LIM protein
AKAP10 A kinase (PRKA) anchor protein 10
ALCAM activated leukocyte cell adhesion molecule
ANXA8L1 annexin A8-like 1
APOB apolipoprotein B
ASGR1 asialoglycoprotein receptor 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASXL1 additional sex combs like transcriptional regulator 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
CASKIN2 CASK interacting protein 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC175 coiled-coil domain containing 175
CCDC92 coiled-coil domain containing 92
CCDC96 coiled-coil domain containing 96
CCR3 chemokine (C-C motif) receptor 3
CDCP1 CUB domain containing protein 1
CDT1 chromatin licensing and DNA replication factor 1
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEL carboxyl ester lipase
CENPE centromere protein E, 312kDa
CEP83 centrosomal protein 83kDa
CHEK2 checkpoint kinase 2
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLIP2 CAP-GLY domain containing linker protein 2
COL6A6 collagen, type VI, alpha 6
CORIN corin, serine peptidase
CPA5 carboxypeptidase A5
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSNK2B casein kinase 2, beta polypeptide
CTAGE5 CTAGE family, member 5
CUL9 cullin 9
DGKG diacylglycerol kinase, gamma 90kDa
DHRS7C dehydrogenase/reductase (SDR family) member 7C
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DISC1 disrupted in schizophrenia 1
DNAH10 dynein, axonemal, heavy chain 10
DNAH2 dynein, axonemal, heavy chain 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNASE1 deoxyribonuclease I
DOCK9 dedicator of cytokinesis 9
DSP desmoplakin
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUOXA1 dual oxidase maturation factor 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ELP2 elongator acetyltransferase complex subunit 2
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ESRP1 epithelial splicing regulatory protein 1
EVA1A eva-1 homolog A (C. elegans)
EVX2 even-skipped homeobox 2
FAM178B family with sequence similarity 178, member B
FAM86B2 family with sequence similarity 86, member B2
FAM90A1 family with sequence similarity 90, member A1
FN1 fibronectin 1
FUNDC2 FUN14 domain containing 2
GCLM glutamate-cysteine ligase, modifier subunit
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC9 histone deacetylase 9
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIATL1 hippocampus abundant transcript-like 1
HIP1 huntingtin interacting protein 1
HIST1H4D histone cluster 1, H4d
HMHA1 histocompatibility (minor) HA-1
HPS4 Hermansky-Pudlak syndrome 4
HRNR hornerin
HUNK hormonally up-regulated Neu-associated kinase
HYDIN HYDIN, axonemal central pair apparatus protein
IL17D interleukin 17D
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRS1 insulin receptor substrate 1
KALRN kalirin, RhoGEF kinase
KIAA1671 KIAA1671
KIDINS220 kinase D-interacting substrate, 220kDa
KIF3A kinesin family member 3A
KIF7 kinesin family member 7
KMT2C lysine (K)-specific methyltransferase 2C
KRT79 keratin 79, type II
LRRN4 leucine rich repeat neuronal 4
LTC4S leukotriene C4 synthase
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1
MED14 mediator complex subunit 14
MEGF6 multiple EGF-like-domains 6
MGAM maltase-glucoamylase
MRGPRX1 MAS-related GPR, member X1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MUC16 mucin 16, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBPC1 myosin binding protein C, slow type
MYLK4 myosin light chain kinase family, member 4
MYO7B myosin VIIB
MYOM3 myomesin 3
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NEBL nebulette
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NLRP4 NLR family, pyrin domain containing 4
NLRP5 NLR family, pyrin domain containing 5
NOL6 nucleolar protein 6 (RNA-associated)
NOMO2 NODAL modulator 2
NPSR1 neuropeptide S receptor 1
NRSN1 neurensin 1
NSD1 nuclear receptor binding SET domain protein 1
NUF2 NUF2, NDC80 kinetochore complex component
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OBP2A odorant binding protein 2A
OR13A1 olfactory receptor, family 13, subfamily A, member 1
OR14A2 olfactory receptor, family 14, subfamily A, member 2
OR52E4 olfactory receptor, family 52, subfamily E, member 4
OR5M8 olfactory receptor, family 5, subfamily M, member 8
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
PARP10 poly (ADP-ribose) polymerase family, member 10
PAX6 paired box 6
PCDHB12 protocadherin beta 12
PCDHB3 protocadherin beta 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCLO piccolo presynaptic cytomatrix protein
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PCNXL4 pecanex-like 4 (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDCD11 programmed cell death 11
PDCD6IP programmed cell death 6 interacting protein
PFAS phosphoribosylformylglycinamidine synthase
PICK1 protein interacting with PRKCA 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PLB1 phospholipase B1
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLXNB3 plexin B3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPA2 pyrophosphatase (inorganic) 2
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRDM2 PR domain containing 2, with ZNF domain
PRG4 proteoglycan 4
PRKCG protein kinase C, gamma
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRRC2A proline-rich coiled-coil 2A
PTEN phosphatase and tensin homolog
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRH protein tyrosine phosphatase, receptor type, H
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNASET2 ribonuclease T2
RNF122 ring finger protein 122
RNF213 ring finger protein 213
RP1L1 retinitis pigmentosa 1-like 1
RPS3 ribosomal protein S3
RYR2 ryanodine receptor 2 (cardiac)
SACK1H scaffolding CK1 anchoring protein H
SAFB scaffold attachment factor B
SDC3 syndecan 3
SEPT10 septin 10
SIK3 SIK family kinase 3
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
SNAI1 snail family zinc finger 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STAB2 stabilin 2
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT4 signal transducer and activator of transcription 4
STEAP4 STEAP family member 4
STK10 serine/threonine kinase 10
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TM2D3 TM2 domain containing 3
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNR tenascin R
TOR2A torsin family 2, member A
TP53 tumor protein p53
TRMT6 tRNA methyltransferase 6
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSLIG1 tRNA splicing ligase complex subunit 1
TTC25 tetratricopeptide repeat domain 25
TTN titin
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
USH2A Usher syndrome 2A (autosomal recessive, mild)
VEZT vezatin, adherens junctions transmembrane protein
VNN2 vanin 2
VRTN vertebrae development associated
WDR27 WD repeat domain 27
WDR7 WD repeat domain 7
WNT6 wingless-type MMTV integration site family, member 6
WRN Werner syndrome, RecQ helicase-like
XIRP2 xin actin binding repeat containing 2
ZNF221 zinc finger protein 221
ZNF225 zinc finger protein 225
ZNF280C zinc finger protein 280C
ZNF343 zinc finger protein 343
ZNF720 zinc finger protein 720
ZP4 zona pellucida glycoprotein 4
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2