D-566MG Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

367 genes with high or low expression in D-566MG relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
RAB23 RAB23, member RAS oncogene family 3.41179
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.69363
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 2.6918
COL10A1 collagen, type X, alpha 1 2.56657
PDAP1 PDGFA associated protein 1 2.5532
ASPN asporin 2.53218
TAGLN transgelin 2.31379
TMEM43 transmembrane protein 43 2.28418
MYH9 myosin, heavy chain 9, non-muscle 2.2653
PRRX1 paired related homeobox 1 2.25783
COPS6 COP9 signalosome subunit 6 2.04779
EIF3I eukaryotic translation initiation factor 3, subunit I 2.0251
CALD1 caldesmon 1 2.00182
GARS glycyl-tRNA synthetase 1.98997
WISP1 WNT1 inducible signaling pathway protein 1 1.98507
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.96791
TPM4 tropomyosin 4 1.93377
EIF5 eukaryotic translation initiation factor 5 1.91929
CH25H cholesterol 25-hydroxylase 1.90654
CADM3 cell adhesion molecule 3 1.89157
NGF nerve growth factor (beta polypeptide) 1.87753
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.86295
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.85935
PDCD1LG2 programmed cell death 1 ligand 2 1.84129
FAP fibroblast activation protein, alpha 1.8117
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 1.78634
EDC3 enhancer of mRNA decapping 3 1.78164
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 1.76203
GADD45A growth arrest and DNA-damage-inducible, alpha 1.74987
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1.7463
SYNC syncoilin, intermediate filament protein 1.71661
KCNK2 potassium channel, two pore domain subfamily K, member 2 1.71581
POLR1E polymerase (RNA) I polypeptide E, 53kDa 1.69526
TRAPPC3 trafficking protein particle complex 3 1.69295
PDCD5 programmed cell death 5 1.66549
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.66539
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.66466
PLN phospholamban 1.65506
ORC5 origin recognition complex, subunit 5 1.65139
SULF1 sulfatase 1 1.64542
TTC26 tetratricopeptide repeat domain 26 1.64516
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.64274
AVEN apoptosis, caspase activation inhibitor 1.64135
ADAM12 ADAM metallopeptidase domain 12 1.63208
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1.605
BAG2 BCL2-associated athanogene 2 1.60247
CLIC4 chloride intracellular channel 4 1.59147
KCTD15 potassium channel tetramerization domain containing 15 1.5829
SH3BGR SH3 domain binding glutamate-rich protein 1.57997
STK17A serine/threonine kinase 17a 1.56569
POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.56445
DAPK3 death-associated protein kinase 3 1.56194
EIF5A eukaryotic translation initiation factor 5A 1.55546
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.54977
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 1.54594
OXSR1 oxidative stress responsive 1 1.53388
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.53157
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.527
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.52146
TAC1 tachykinin, precursor 1 1.52143
RANGAP1 Ran GTPase activating protein 1 1.51492
IL13RA2 interleukin 13 receptor, alpha 2 1.51223
STAC SH3 and cysteine rich domain 1.51119
CUL1 cullin 1 1.50682
BGN biglycan 1.50317
RANBP1 RAN binding protein 1 1.4883
CTGF connective tissue growth factor 1.48599
ECHDC1 ethylmalonyl-CoA decarboxylase 1 1.47835
KPNA4 karyopherin alpha 4 (importin alpha 3) 1.47774
TWISTNB TWIST neighbor 1.46931
RNH1 ribonuclease/angiogenin inhibitor 1 1.46812
KCTD9 potassium channel tetramerization domain containing 9 1.46349
ADGRA2 adhesion G protein-coupled receptor A2 1.45312
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 1.44807
PTX3 pentraxin 3, long 1.44617
ACTA2 actin, alpha 2, smooth muscle, aorta 1.44533
GLIPR1 GLI pathogenesis-related 1 1.4358
BCL7B B-cell CLL/lymphoma 7B 1.4348
RPP14 ribonuclease P/MRP 14kDa subunit 1.4293
LOXL1 lysyl oxidase-like 1 1.42868
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 1.42684
PNMA1 paraneoplastic Ma antigen 1 1.42527
THOC5 THO complex 5 1.42398
BUD31 BUD31 homolog (S. cerevisiae) 1.42357
EN1 engrailed homeobox 1 1.41683

low expression

Symbol Name Standardized Value
STAMBP STAM binding protein -3.53725
ZNF442 zinc finger protein 442 -3.51554
NCR2 natural cytotoxicity triggering receptor 2 -3.07944
A4GALT alpha 1,4-galactosyltransferase -2.86205
RAB11FIP1 RAB11 family interacting protein 1 (class I) -2.85559
CADM4 cell adhesion molecule 4 -2.84999
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -2.84383
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 -2.78983
TRAF3IP3 TRAF3 interacting protein 3 -2.75319
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.74399
TLX3 T-cell leukemia homeobox 3 -2.74216
GRAMD1C GRAM domain containing 1C -2.74096
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -2.72649
CPEB3 cytoplasmic polyadenylation element binding protein 3 -2.66863
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 -2.63373
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.63123
USP6 ubiquitin specific peptidase 6 -2.52525
CRYBB3 crystallin, beta B3 -2.52441
KIAA1045 KIAA1045 -2.50525
HSPA1L heat shock 70kDa protein 1-like -2.48312
AKAP5 A kinase (PRKA) anchor protein 5 -2.47878
SYT5 synaptotagmin V -2.47374
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.46369
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -2.42411
DIDO1 death inducer-obliterator 1 -2.42201
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -2.41612
ARHGAP24 Rho GTPase activating protein 24 -2.41611
MYT1 myelin transcription factor 1 -2.3862
MTSS1 metastasis suppressor 1 -2.3792
ETV2 ets variant 2 -2.37177
ANKRD55 ankyrin repeat domain 55 -2.35503
FRMPD1 FERM and PDZ domain containing 1 -2.34309
LENEP lens epithelial protein -2.29978
NR5A2 nuclear receptor subfamily 5, group A, member 2 -2.29685
DPEP2 dipeptidase 2 -2.25926
LRP2 low density lipoprotein receptor-related protein 2 -2.23579
NELFA negative elongation factor complex member A -2.22505
PRY PTPN13-like, Y-linked -2.2214
JADE2 jade family PHD finger 2 -2.21132
CRNN cornulin -2.16865
SHANK1 SH3 and multiple ankyrin repeat domains 1 -2.16477
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -2.16217
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -2.15433
PNLIPRP2 pancreatic lipase-related protein 2 -2.15276
CRYGA crystallin, gamma A -2.13133
GP2 glycoprotein 2 (zymogen granule membrane) -2.12648
TNMD tenomodulin -2.12526
GPR18 G protein-coupled receptor 18 -2.12487
TAC3 tachykinin 3 -2.10731
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -2.10541
CAMP cathelicidin antimicrobial peptide -2.09687
NHLRC2 NHL repeat containing 2 -2.08792
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 -2.06069
CSNK1D casein kinase 1, delta -2.0517
HSPA1A heat shock 70kDa protein 1A -2.05036
GJD2 gap junction protein, delta 2, 36kDa -2.042
GRIK4 glutamate receptor, ionotropic, kainate 4 -2.03969
CBLN1 cerebellin 1 precursor -2.03471
CCR3 chemokine (C-C motif) receptor 3 -2.03102
DCSTAMP dendrocyte expressed seven transmembrane protein -2.03028
PI15 peptidase inhibitor 15 -2.02678
CRYGC crystallin, gamma C -2.02578
IL12B interleukin 12B -2.01702
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -2.00171
CORO2A coronin, actin binding protein, 2A -1.9941
LY75 lymphocyte antigen 75 -1.99313
TF transferrin -1.98964
POU4F2 POU class 4 homeobox 2 -1.98848
CTSW cathepsin W -1.98759
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -1.98742
CX3CL1 chemokine (C-X3-C motif) ligand 1 -1.98311
MED13 mediator complex subunit 13 -1.98034
RGS14 regulator of G-protein signaling 14 -1.98003
NCAN neurocan -1.97592
PDZK1IP1 PDZK1 interacting protein 1 -1.97296
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.97054
ADGRF5 adhesion G protein-coupled receptor F5 -1.96717
PPL periplakin -1.96532
DCC DCC netrin 1 receptor -1.96266
FBXO2 F-box protein 2 -1.96226
MGMT O-6-methylguanine-DNA methyltransferase -1.95525
VWA5A von Willebrand factor A domain containing 5A -1.95214
CPLX3 complexin 3 -1.95023
ZMYM2 zinc finger, MYM-type 2 -1.92925
SCGB1D2 secretoglobin, family 1D, member 2 -1.91002
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -1.89001
MMRN1 multimerin 1 -1.88867
PRKG2 protein kinase, cGMP-dependent, type II -1.88708
LOC440792 proline dehydrogenase (oxidase) 1 pseudogene -1.87889
EGFL7 EGF-like-domain, multiple 7 -1.8788
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -1.86551
NF1 neurofibromin 1 -1.86548
KIAA1109 KIAA1109 -1.86231
CFHR5 complement factor H-related 5 -1.85218
LTB lymphotoxin beta (TNF superfamily, member 3) -1.84922
RAB40C RAB40C, member RAS oncogene family -1.84856
SEC24C SEC24 family member C -1.84488
LST1 leukocyte specific transcript 1 -1.84445
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -1.83881
NXPE4 neurexophilin and PC-esterase domain family, member 4 -1.83328
SALL2 spalt-like transcription factor 2 -1.82277
IL18R1 interleukin 18 receptor 1 -1.82267
PTH2R parathyroid hormone 2 receptor -1.82076
GORASP2 golgi reassembly stacking protein 2, 55kDa -1.82067
SLC44A4 solute carrier family 44, member 4 -1.81989
IGHMBP2 immunoglobulin mu binding protein 2 -1.81875
LCN1 lipocalin 1 -1.80829
SPINK5 serine peptidase inhibitor, Kazal type 5 -1.80434
INSL6 insulin-like 6 -1.7982
WBP2 WW domain binding protein 2 -1.79487
WIPF2 WAS/WASL interacting protein family, member 2 -1.79428
RPE65 retinal pigment epithelium-specific protein 65kDa -1.78804
IGSF1 immunoglobulin superfamily, member 1 -1.78074
TRPM6 transient receptor potential cation channel, subfamily M, member 6 -1.77944
GPR6 G protein-coupled receptor 6 -1.77294
NCOA3 nuclear receptor coactivator 3 -1.76786
SMAD9 SMAD family member 9 -1.75991
DSC2 desmocollin 2 -1.75969
CCR2 chemokine (C-C motif) receptor 2 -1.75491
CD79A CD79a molecule, immunoglobulin-associated alpha -1.7531
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -1.75291
ZNF142 zinc finger protein 142 -1.74926
GRTP1 growth hormone regulated TBC protein 1 -1.74713
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -1.74656
LOC284244 uncharacterized LOC284244 -1.74626
CD1B CD1b molecule -1.74354
MAGEL2 melanoma antigen family L2 -1.73976
INADL InaD-like (Drosophila) -1.73971
SVIL supervillin -1.73418
MB myoglobin -1.73185
IDI1 isopentenyl-diphosphate delta isomerase 1 -1.73103
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -1.72567
SPIN2A spindlin family, member 2A -1.72268
JMJD6 jumonji domain containing 6 -1.71762
FGF17 fibroblast growth factor 17 -1.71425
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -1.70868
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -1.70853
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -1.70759
GPR19 G protein-coupled receptor 19 -1.7071
ASIP agouti signaling protein -1.70589
SLC6A16 solute carrier family 6, member 16 -1.70221
JCHAIN joining chain of multimeric IgA and IgM -1.70082
RAPSN receptor-associated protein of the synapse -1.68956
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2 -1.68361
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -1.68357
PGS1 phosphatidylglycerophosphate synthase 1 -1.68333
CDRT1 CMT1A duplicated region transcript 1 -1.68255
ZMYND8 zinc finger, MYND-type containing 8 -1.6817
ZFC3H1 zinc finger, C3H1-type containing -1.68158
LMTK2 lemur tyrosine kinase 2 -1.68072
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -1.67669
RAB20 RAB20, member RAS oncogene family -1.67523
TP73 tumor protein p73 -1.67494
CA5B carbonic anhydrase VB, mitochondrial -1.67299
GSC2 goosecoid homeobox 2 -1.67138
MYF6 myogenic factor 6 (herculin) -1.67047
MTL5 metallothionein-like 5, testis-specific (tesmin) -1.67024
ICAM2 intercellular adhesion molecule 2 -1.6644
PLA2G2E phospholipase A2, group IIE -1.66262
PROC protein C (inactivator of coagulation factors Va and VIIIa) -1.66214
CD1D CD1d molecule -1.66076
PLG plasminogen -1.65786
DUOX2 dual oxidase 2 -1.65616
RNF25 ring finger protein 25 -1.65481
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.65146
ACSM3 acyl-CoA synthetase medium-chain family member 3 -1.6473
REM1 RAS (RAD and GEM)-like GTP-binding 1 -1.64647
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene -1.63346
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -1.62929
LALBA lactalbumin, alpha- -1.62867
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -1.62575
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -1.6257
SNCB synuclein, beta -1.6202
DCAF7 DDB1 and CUL4 associated factor 7 -1.61768
AZU1 azurocidin 1 -1.61542
KCNK7 potassium channel, two pore domain subfamily K, member 7 -1.61101
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) -1.60931
HOXD3 homeobox D3 -1.60893
ULK4 unc-51 like kinase 4 -1.60857
ALPPL2 alkaline phosphatase, placental-like 2 -1.6064
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 -1.59968
TFEC transcription factor EC -1.59777
PRODH2 proline dehydrogenase (oxidase) 2 -1.5975
MPPED1 metallophosphoesterase domain containing 1 -1.58739
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -1.58449
LGALS7 lectin, galactoside-binding, soluble, 7 -1.5814
TAL1 T-cell acute lymphocytic leukemia 1 -1.57114
INPP5J inositol polyphosphate-5-phosphatase J -1.56735
MYH4 myosin, heavy chain 4, skeletal muscle -1.56628
EDN2 endothelin 2 -1.56583
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 -1.56516
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.56478
HIST1H4D histone cluster 1, H4d -1.56467
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -1.56377
CHD2 chromodomain helicase DNA binding protein 2 -1.56079
NIPBL Nipped-B homolog (Drosophila) -1.55993
UPK2 uroplakin 2 -1.55689
ATP7B ATPase, Cu++ transporting, beta polypeptide -1.55446
PRSS16 protease, serine, 16 (thymus) -1.55001
BAZ2B bromodomain adjacent to zinc finger domain, 2B -1.54977
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -1.54878
PARD6B par-6 family cell polarity regulator beta -1.54655
MAT1A methionine adenosyltransferase I, alpha -1.54504
IL23A interleukin 23, alpha subunit p19 -1.54289
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -1.54041
HIST1H3I histone cluster 1, H3i -1.53732
DBP D site of albumin promoter (albumin D-box) binding protein -1.53409
WIF1 WNT inhibitory factor 1 -1.531
SOX3 SRY (sex determining region Y)-box 3 -1.52971
LAMB4 laminin, beta 4 -1.52799
LMBR1L limb development membrane protein 1-like -1.52672
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -1.52286
MSH4 mutS homolog 4 -1.52171
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -1.52113
PRAME preferentially expressed antigen in melanoma -1.51815
NCF4 neutrophil cytosolic factor 4, 40kDa -1.51651
GAK cyclin G associated kinase -1.51361
TREX2 three prime repair exonuclease 2 -1.51289
FKBP5 FK506 binding protein 5 -1.51236
PER1 period circadian clock 1 -1.51144
KRT38 keratin 38, type I -1.51036
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 -1.5096
CD177 CD177 molecule -1.50882
EPOR erythropoietin receptor -1.50782
INSL4 insulin-like 4 (placenta) -1.50399
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -1.50363
FLRT3 fibronectin leucine rich transmembrane protein 3 -1.50169
CPS1-IT1 CPS1 intronic transcript 1 -1.50108
AP3B2 adaptor-related protein complex 3, beta 2 subunit -1.49921
FGF16 fibroblast growth factor 16 -1.49904
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -1.49881
PTPRD protein tyrosine phosphatase, receptor type, D -1.49829
TNN tenascin N -1.49564
CLCN2 chloride channel, voltage-sensitive 2 -1.4944
PGRMC2 progesterone receptor membrane component 2 -1.49272
SNCAIP synuclein, alpha interacting protein -1.49231
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -1.48755
GALR3 galanin receptor 3 -1.4853
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.48465
IGHD immunoglobulin heavy constant delta -1.48417
SMCP sperm mitochondria-associated cysteine-rich protein -1.48217
CCL5 chemokine (C-C motif) ligand 5 -1.48201
OTC ornithine carbamoyltransferase -1.48187
ACSBG2 acyl-CoA synthetase bubblegum family member 2 -1.47615
KIAA0907 KIAA0907 -1.47526
OSBP oxysterol binding protein -1.47297
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -1.47076
TM9SF3 transmembrane 9 superfamily member 3 -1.4672
CALCOCO1 calcium binding and coiled-coil domain 1 -1.46251
MAP3K9 mitogen-activated protein kinase kinase kinase 9 -1.45957
BPTF bromodomain PHD finger transcription factor -1.45889
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -1.45794
SPICE1 spindle and centriole associated protein 1 -1.45432
FTCD formimidoyltransferase cyclodeaminase -1.45301
HIST1H2AL histone cluster 1, H2al -1.45105
NLK nemo-like kinase -1.45069
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -1.4502
MYBPH myosin binding protein H -1.44915
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -1.44897
DHRS12 dehydrogenase/reductase (SDR family) member 12 -1.44873
POLR1D polymerase (RNA) I polypeptide D, 16kDa -1.44832
IL24 interleukin 24 -1.44422
DAO D-amino-acid oxidase -1.44339
LCN2 lipocalin 2 -1.44004
KRT12 keratin 12, type I -1.43502
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -1.43365
PHF1 PHD finger protein 1 -1.43306
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -1.43178
PLEK2 pleckstrin 2 -1.43073
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -1.42844
GFRA4 GDNF family receptor alpha 4 -1.42632
IL36RN interleukin 36 receptor antagonist -1.42605
OSBPL2 oxysterol binding protein-like 2 -1.42557
HRG histidine-rich glycoprotein -1.42507
UGT8 UDP glycosyltransferase 8 -1.42424
RFPL3S RFPL3 antisense -1.42319
EDDM3B epididymal protein 3B -1.42247
SPRR2C small proline-rich protein 2C (pseudogene) -1.42213
ATP8B4 ATPase, class I, type 8B, member 4 -1.42126
FKBP6 FK506 binding protein 6, 36kDa -1.41816
USP34 ubiquitin specific peptidase 34 -1.41621
CSN2 casein beta -1.41604