DA-79-ZD74_10uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=10uM, Acacetin, Melanin Inhibitors;Xanthine Oxidase Inhibitors targeting XDH (Novartis, 5280442)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/5280442
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Genes

5 genes differentially expressed following the DA-79-ZD74_10uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
MT1E metallothionein 1E 0.290683
MT1X metallothionein 1X 0.272914
MT2A metallothionein 2A 0.248527

decreased expression

Symbol Name Standardized Value
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.522567
RPS11 ribosomal protein S11 -0.36667