DAB2IP Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description DAB2 interacting protein|DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).[supplied by OMIM, May 2010] (NCBI Entrez Gene Database, 153090)
External Link http://www.ncbi.nlm.nih.gov/gene/153090
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Genes

40 interacting proteins for DAB2IP from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
AXIN1 axin 1
BIRC3 baculoviral IAP repeat containing 3
CUL1 cullin 1
CUL4A cullin 4A
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GSK3B glycogen synthase kinase 3 beta
HRAS Harvey rat sarcoma viral oncogene homolog
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MRAS muscle RAS oncogene homolog
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
RBX1 ring-box 1, E3 ubiquitin protein ligase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SKP1 S-phase kinase-associated protein 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta