| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | dachshund family transcription factor 1|This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 1602) |
| External Link | https://ncbi.nlm.nih.gov/gene/1602 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the DACH1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| S100P | S100 calcium binding protein P | 0.0168759 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0156721 |
| HBD | hemoglobin, delta | 0.0113038 |
| LTF | lactotransferrin | 0.0111951 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.01057 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0100861 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0100424 |
| CDC20 | cell division cycle 20 | 0.00996538 |
| KRT19 | keratin 19, type I | 0.00943937 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00934269 |
| PEG3 | paternally expressed 3 | 0.00929569 |
| CLC | Charcot-Leyden crystal galectin | 0.00917477 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00908219 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00907675 |
| RGS1 | regulator of G-protein signaling 1 | 0.00903589 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00899242 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00898569 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00894663 |
| XYLT1 | xylosyltransferase I | 0.00880805 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00866218 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00866023 |
| CA2 | carbonic anhydrase II | 0.00847686 |
| NPTX2 | neuronal pentraxin II | 0.00844339 |
| S100A9 | S100 calcium binding protein A9 | 0.00840294 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00838593 |
| PCNA | proliferating cell nuclear antigen | 0.00822652 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00804395 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00798329 |
| FRZB | frizzled-related protein | 0.00792846 |
| TSPAN7 | tetraspanin 7 | 0.0079246 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00785024 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00780927 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00779142 |
| FCGBP | Fc fragment of IgG binding protein | 0.0077584 |
| TSPAN13 | tetraspanin 13 | 0.00774786 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00774724 |
| CHGB | chromogranin B | 0.00771602 |
| LYZ | lysozyme | 0.00769495 |
| MAP7 | microtubule-associated protein 7 | 0.00768264 |
| MARCKSL1 | MARCKS-like 1 | 0.00763505 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00760563 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00743695 |
| AGR2 | anterior gradient 2 | 0.00740201 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00733384 |
| HBB | hemoglobin, beta | 0.00732333 |
| LXN | latexin | 0.00720137 |
| BEX1 | brain expressed, X-linked 1 | 0.007184 |
| MMP9 | matrix metallopeptidase 9 | 0.00703096 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00701591 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00697439 |
| A2M | alpha-2-macroglobulin | 0.00697061 |
| PLK1 | polo-like kinase 1 | 0.00696966 |
| NTS | neurotensin | 0.0069605 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00692055 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00691043 |
| OLFM1 | olfactomedin 1 | 0.00687826 |
| BRCA1 | breast cancer 1, early onset | 0.00686864 |
| TOB1 | transducer of ERBB2, 1 | 0.00679121 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00670323 |
| WTAP | Wilms tumor 1 associated protein | 0.0064547 |
| CAMP | cathelicidin antimicrobial peptide | 0.00643556 |
| OLFM4 | olfactomedin 4 | 0.00640852 |
| HOPX | HOP homeobox | 0.00640512 |
| TFRC | transferrin receptor | 0.00637856 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00631847 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00624702 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00621384 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00621131 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00620686 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00619924 |
| CSTA | cystatin A (stefin A) | 0.00618886 |
| HEPH | hephaestin | 0.00618178 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00615469 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00614264 |
| TSPAN12 | tetraspanin 12 | 0.00597124 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00595913 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00594357 |
| COL1A2 | collagen, type I, alpha 2 | 0.00591492 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00590779 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.005884 |
| PDGFC | platelet derived growth factor C | 0.00587454 |
| NEK2 | NIMA-related kinase 2 | 0.00584261 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0058343 |
| BLNK | B-cell linker | 0.0058143 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00581281 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00580946 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00577876 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00575567 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00572 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00569774 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0056921 |
| ABHD3 | abhydrolase domain containing 3 | 0.00566721 |
| C7 | complement component 7 | 0.00566064 |
| DCK | deoxycytidine kinase | 0.00564335 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00563722 |
| PRKD3 | protein kinase D3 | 0.00563348 |
| HOXC6 | homeobox C6 | 0.00562519 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00561006 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00558455 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00557637 |
| ANGPT1 | angiopoietin 1 | 0.00557554 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | 0.00555793 |
| MAGED1 | melanoma antigen family D1 | 0.00551277 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00551224 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0055053 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00549786 |
| THAP9-AS1 | THAP9 antisense RNA 1 | 0.0054962 |
| CP | ceruloplasmin (ferroxidase) | 0.00548466 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00547897 |
| TNS3 | tensin 3 | 0.00547178 |
| S100A12 | S100 calcium binding protein A12 | 0.00546951 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00545561 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00544195 |
| SATB2 | SATB homeobox 2 | 0.0054407 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00543917 |
| WT1 | Wilms tumor 1 | 0.00543286 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00542726 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00537405 |
| SRGN | serglycin | 0.0053552 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00535147 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00535046 |
| CYTIP | cytohesin 1 interacting protein | 0.00534259 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00533088 |
| INAVA | innate immunity activator | 0.00531274 |
| OIP5 | Opa interacting protein 5 | 0.00531125 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00531055 |
| XK | X-linked Kx blood group | 0.00530665 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00528133 |
| TRAPPC4 | trafficking protein particle complex 4 | 0.00526175 |
| LY75 | lymphocyte antigen 75 | 0.00526084 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00525667 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00525131 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00524136 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.0052374 |
| DLD | dihydrolipoamide dehydrogenase | 0.00523291 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00519909 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00518591 |
| CD52 | CD52 molecule | 0.00517245 |
| H1-2 | H1.2 linker histone, cluster member | 0.0051594 |
| BPI | bactericidal/permeability-increasing protein | 0.0051553 |
| OLFML3 | olfactomedin-like 3 | 0.0051478 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00514514 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00514381 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00512308 |
| ITM2A | integral membrane protein 2A | 0.00511196 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00510698 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00508714 |
| MPO | myeloperoxidase | 0.00508333 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.00507374 |
| JAG1 | jagged 1 | 0.00507372 |
| CLDN10 | claudin 10 | 0.00506697 |
| WBP5 | WW domain binding protein 5 | 0.00506577 |
| MED28 | mediator complex subunit 28 | 0.00505291 |
| HHEX | hematopoietically expressed homeobox | 0.00505252 |
| COMMD8 | COMM domain containing 8 | 0.00502282 |
| CHN1 | chimerin 1 | 0.00501773 |
| TPD52L1 | tumor protein D52-like 1 | 0.00499702 |
| PDGFD | platelet derived growth factor D | 0.00499073 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00498781 |
| RPA3 | replication protein A3, 14kDa | 0.00497506 |
| CLCA4 | chloride channel accessory 4 | 0.00495587 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00495472 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00494953 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00493893 |
| ZNF331 | zinc finger protein 331 | 0.00492516 |
| ATF1 | activating transcription factor 1 | 0.00491787 |
| FERMT1 | fermitin family member 1 | 0.00491345 |
| GALC | galactosylceramidase | 0.00490396 |
| TMEM50B | transmembrane protein 50B | 0.0049035 |
| CTBP1 | C-terminal binding protein 1 | 0.00490145 |
| PCDH9 | protocadherin 9 | 0.00489904 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00489628 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00488475 |
| ADORA3 | adenosine A3 receptor | 0.00488411 |
| SLBP | stem-loop binding protein | 0.00487712 |
| CYBRD1 | cytochrome b reductase 1 | 0.00487152 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 0.00485929 |
| S100A4 | S100 calcium binding protein A4 | 0.00484915 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00484861 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00483684 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00483191 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.00481361 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.00480061 |
| HLTF | helicase-like transcription factor | 0.00478754 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0047869 |
| PDZD8 | PDZ domain containing 8 | 0.00478595 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00477086 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00474727 |
| FADS1 | fatty acid desaturase 1 | 0.0047382 |
| PSCA | prostate stem cell antigen | 0.00473811 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00472701 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00471879 |
| CDK1 | cyclin-dependent kinase 1 | 0.0046972 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00469134 |
| MXRA5 | matrix-remodelling associated 5 | 0.00467863 |
| RAPSN | receptor-associated protein of the synapse | 0.00467077 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00466884 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00465835 |
| KIF18B | kinesin family member 18B | 0.00464097 |
| CLIC5 | chloride intracellular channel 5 | 0.00463621 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00463084 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00462783 |
| GMFG | glia maturation factor, gamma | 0.00462131 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00461099 |
| MMP8 | matrix metallopeptidase 8 | 0.0046061 |
| CTSG | cathepsin G | 0.00460584 |
| CCNF | cyclin F | 0.0046056 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.00459298 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 0.00458443 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00458256 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G | 0.00457563 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.00457463 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00457236 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00456819 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00456257 |
| LBR | lamin B receptor | 0.0045506 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00454896 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.00453034 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0045283 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00452597 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00452483 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0044961 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00449584 |
| HMGB2 | high mobility group box 2 | 0.00449426 |
| RBM47 | RNA binding motif protein 47 | 0.0044926 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.00448278 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00448098 |
| MT1M | metallothionein 1M | 0.00447684 |
| ADCY2 | adenylate cyclase 2 (brain) | 0.00445623 |
| PRKCB | protein kinase C, beta | 0.00445342 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.0044458 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00444093 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00444002 |
| EAF2 | ELL associated factor 2 | 0.00443941 |
| EHF | ets homologous factor | 0.00443732 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00442426 |
| CCNB1 | cyclin B1 | 0.00442156 |
| TMEM106B | transmembrane protein 106B | 0.00439894 |
| NID2 | nidogen 2 (osteonidogen) | 0.00439721 |
| CCND2 | cyclin D2 | 0.00439536 |
| GPM6B | glycoprotein M6B | 0.00438756 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00438554 |
| ATP5ME | ATP synthase membrane subunit e | 0.00436451 |
| PAQR3 | progestin and adipoQ receptor family member III | 0.00436336 |
| C1D | C1D nuclear receptor corepressor | 0.00435991 |
| CD69 | CD69 molecule | 0.00435487 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00434864 |
| CTSD | cathepsin D | 0.0043372 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00432903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0138423 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.0127104 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0110119 |
| BMP4 | bone morphogenetic protein 4 | -0.0109148 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00997023 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.00955495 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.0086996 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00855653 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00845827 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00785636 |
| S100A10 | S100 calcium binding protein A10 | -0.00776417 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00773416 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00762373 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00756093 |
| PFKP | phosphofructokinase, platelet | -0.00756002 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00748674 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00728659 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00726565 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00716004 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00714642 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00709056 |
| FRY | furry homolog (Drosophila) | -0.00694408 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00686132 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00667369 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00664966 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00655146 |
| NKX2-1 | NK2 homeobox 1 | -0.00654754 |
| MYOF | myoferlin | -0.00653555 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00650916 |
| MAOB | monoamine oxidase B | -0.00646418 |
| ADM | adrenomedullin | -0.00644534 |
| DSP | desmoplakin | -0.00641434 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00633342 |
| KRT14 | keratin 14, type I | -0.00627293 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00624742 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00622884 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00621707 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00618922 |
| NVL | nuclear VCP-like | -0.00615385 |
| SP110 | SP110 nuclear body protein | -0.00606543 |
| SFTPB | surfactant protein B | -0.00605272 |
| MYO6 | myosin VI | -0.00604454 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00602529 |
| SHTN1 | shootin 1 | -0.00598323 |
| SMC1A | structural maintenance of chromosomes 1A | -0.005973 |
| GPR88 | G protein-coupled receptor 88 | -0.00596065 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00592145 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00588629 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00588331 |
| MYO1B | myosin IB | -0.00588213 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | -0.00587585 |
| TPM2 | tropomyosin 2 (beta) | -0.0058652 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00583111 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00582033 |
| TJP2 | tight junction protein 2 | -0.00581088 |
| PMM2 | phosphomannomutase 2 | -0.00575815 |
| RBM34 | RNA binding motif protein 34 | -0.00570662 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00570352 |
| USP18 | ubiquitin specific peptidase 18 | -0.00564836 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00564433 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00563521 |
| ACKR3 | atypical chemokine receptor 3 | -0.00561205 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0055698 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00556676 |
| IL32 | interleukin 32 | -0.00554484 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00548388 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00547613 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00545233 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00542727 |
| SMAD3 | SMAD family member 3 | -0.00540549 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00532419 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00526516 |
| AMACR | alpha-methylacyl-CoA racemase | -0.00524947 |
| GAB2 | GRB2-associated binding protein 2 | -0.00523648 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00523459 |
| CAVIN3 | caveolae associated protein 3 | -0.00523044 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00521318 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | -0.00520908 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0051628 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0051544 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00515394 |
| TPD52 | tumor protein D52 | -0.00515242 |
| IPO7 | importin 7 | -0.00514892 |
| RCAN1 | regulator of calcineurin 1 | -0.00511598 |
| ABLIM1 | actin binding LIM protein 1 | -0.00510982 |
| SDCBP | syndecan binding protein (syntenin) | -0.00510585 |
| PALMD | palmdelphin | -0.00509907 |
| KLF6 | Kruppel-like factor 6 | -0.0050936 |
| MVP | major vault protein | -0.00509109 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00502934 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0050045 |
| LOXL2 | lysyl oxidase-like 2 | -0.00499045 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00495865 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00494606 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00492864 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.004899 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00489189 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0048547 |
| KLK10 | kallikrein-related peptidase 10 | -0.00484983 |
| MSRB1 | methionine sulfoxide reductase B1 | -0.00484871 |
| TKTL1 | transketolase-like 1 | -0.00482817 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00481766 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00478398 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00478042 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00477224 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00477075 |
| NAV2 | neuron navigator 2 | -0.00476822 |
| MPDZ | multiple PDZ domain protein | -0.00473683 |
| CRYAB | crystallin, alpha B | -0.00473581 |
| CES1 | carboxylesterase 1 | -0.00468204 |
| PUM3 | pumilio RNA binding family member 3 | -0.0046759 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | -0.00467018 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00466606 |
| FBN2 | fibrillin 2 | -0.00466487 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00466165 |
| HOMER3 | homer scaffolding protein 3 | -0.00466135 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00466061 |
| BAG3 | BCL2-associated athanogene 3 | -0.00464778 |
| DEFB4A | defensin, beta 4A | -0.00464724 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00464451 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00464195 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00462395 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -0.00462362 |
| NOX4 | NADPH oxidase 4 | -0.00461697 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00460604 |
| DENND5A | DENN/MADD domain containing 5A | -0.00460431 |
| WIF1 | WNT inhibitory factor 1 | -0.00460275 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00459026 |
| KRT23 | keratin 23, type I | -0.00457868 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00457534 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00455408 |
| EPPK1 | epiplakin 1 | -0.00454729 |
| PSAP | prosaposin | -0.00454323 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00453645 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.00452641 |
| SPRR3 | small proline-rich protein 3 | -0.00451827 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00450752 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00450104 |
| RRAD | Ras-related associated with diabetes | -0.0044951 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00449196 |
| HAGH | hydroxyacylglutathione hydrolase | -0.00448605 |
| STK10 | serine/threonine kinase 10 | -0.00446139 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00446031 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00445974 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00445629 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00443577 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00443576 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00443346 |
| ODAM | odontogenic, ameloblast asssociated | -0.00441622 |
| CARD10 | caspase recruitment domain family, member 10 | -0.0044115 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0044084 |
| DPYS | dihydropyrimidinase | -0.00438856 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00438112 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00438047 |
| TAGLN2 | transgelin 2 | -0.0043794 |
| EFNA1 | ephrin-A1 | -0.00437938 |
| IRF7 | interferon regulatory factor 7 | -0.00437068 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00435414 |
| AMOTL2 | angiomotin like 2 | -0.00433526 |
| F12 | coagulation factor XII (Hageman factor) | -0.00432595 |
| KLK3 | kallikrein-related peptidase 3 | -0.00430174 |
| FAIM | Fas apoptotic inhibitory molecule | -0.00427762 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00427165 |
| CYP7A1 | cytochrome P450, family 7, subfamily A, polypeptide 1 | -0.00427139 |
| E2F2 | E2F transcription factor 2 | -0.00426374 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | -0.00425658 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00424721 |
| IL1RN | interleukin 1 receptor antagonist | -0.0042271 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00421985 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00421559 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.0042071 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00417768 |
| ZNF395 | zinc finger protein 395 | -0.0041643 |
| LIF | leukemia inhibitory factor | -0.00416063 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00415874 |
| MYBPC1 | myosin binding protein C, slow type | -0.00415471 |
| MCAM | melanoma cell adhesion molecule | -0.00414596 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00414136 |
| COPA | coatomer protein complex, subunit alpha | -0.00413832 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00413362 |
| CREB5 | cAMP responsive element binding protein 5 | -0.00412678 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.00411337 |
| SVIL | supervillin | -0.00411069 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -0.00410592 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00410094 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.0041008 |
| AQP9 | aquaporin 9 | -0.00409725 |
| TPP1 | tripeptidyl peptidase I | -0.00408927 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00408437 |
| GOLGB1 | golgin B1 | -0.00407764 |
| MX1 | MX dynamin-like GTPase 1 | -0.00407156 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00407125 |
| GATA6 | GATA binding protein 6 | -0.00406944 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00406933 |
| FNBP1L | formin binding protein 1-like | -0.00406812 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00406399 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00405903 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00405817 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -0.00404989 |
| CFB | complement factor B | -0.00404639 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.0040453 |
| EGR1 | early growth response 1 | -0.00402967 |
| MCM2 | minichromosome maintenance complex component 2 | -0.0040292 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.00402427 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00402291 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00402144 |
| PLS3 | plastin 3 | -0.00401631 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | -0.00401473 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00401351 |
| GLYAT | glycine-N-acyltransferase | -0.00401189 |
| KLF9 | Kruppel-like factor 9 | -0.00400027 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00398426 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00397928 |
| MT2A | metallothionein 2A | -0.00395586 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.00393603 |
| DNMBP | dynamin binding protein | -0.00393264 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00393119 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00392862 |
| PODXL | podocalyxin-like | -0.00391955 |
| MKRN1 | makorin ring finger protein 1 | -0.00391759 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00391509 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00391396 |
| SFN | stratifin | -0.00391118 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | -0.00390441 |
| RTN2 | reticulon 2 | -0.00390226 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00390217 |
| IL17B | interleukin 17B | -0.00389783 |
| R3HDM4 | R3H domain containing 4 | -0.00389728 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00389506 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00388317 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0038785 |
| RAB29 | RAB29, member RAS oncogene family | -0.00387195 |
| SAMHD1 | SAM domain and HD domain 1 | -0.00387085 |
| CDK18 | cyclin-dependent kinase 18 | -0.00386666 |
| LOX | lysyl oxidase | -0.00386571 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00386365 |
| DACH1 | dachshund family transcription factor 1 | -0.00386031 |
| CFI | complement factor I | -0.00384759 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -0.00383869 |
| C9 | complement component 9 | -0.00382824 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00382411 |
| GSPT1 | G1 to S phase transition 1 | -0.00381702 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -0.00380984 |
| KLK13 | kallikrein-related peptidase 13 | -0.00380611 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00379997 |
| SP140L | SP140 nuclear body protein-like | -0.00379663 |
| SACS | sacsin molecular chaperone | -0.00379596 |
| PHF11 | PHD finger protein 11 | -0.00378712 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00377669 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00376821 |