DACT1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description dishevelled-binding antagonist of beta-catenin 1|The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 51339)
External Link http://www.ncbi.nlm.nih.gov/gene/51339
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Genes

415 interacting proteins for DACT1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABRA actin binding Rho activating protein
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADNP activity-dependent neuroprotector homeobox
AGK acylglycerol kinase
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AHDC1 AT hook, DNA binding motif, containing 1
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AJAP1 adherens junctions associated protein 1
ALPK3 alpha-kinase 3
ALYREF Aly/REF export factor
ANLN anillin, actin binding protein
AP4B1 adaptor-related protein complex 4, beta 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARG1 arginase 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATG14 autophagy related 14
ATM ATM serine/threonine kinase
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
BECN1 beclin 1, autophagy related
BPTF bromodomain PHD finger transcription factor
BRWD1 bromodomain and WD repeat domain containing 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C20ORF57 chromosome 20 open reading frame 57
C2ORF16 chromosome 2 open reading frame 16
C4A complement component 4A (Rodgers blood group)
C7ORF25 chromosome 7 open reading frame 25
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALCOCO2 calcium binding and coiled-coil domain 2
CALD1 caldesmon 1
CASC5 cancer susceptibility candidate 5
CBFB core-binding factor, beta subunit
CBX6 chromobox homolog 6
CCM2L cerebral cavernous malformation 2-like
CDC26 cell division cycle 26
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDV3 CDV3 homolog (mouse)
CENPV centromere protein V
CEP135 centrosomal protein 135kDa
CEP170 centrosomal protein 170kDa
CEP350 centrosomal protein 350kDa
CEP55 centrosomal protein 55kDa
CFL1 cofilin 1 (non-muscle)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CKAP4 cytoskeleton-associated protein 4
CLEC11A C-type lectin domain family 11, member A
CLSTN1 calsyntenin 1
CNOT11 CCR4-NOT transcription complex, subunit 11
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTN5 contactin 5
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CROCC ciliary rootlet coiled-coil, rootletin
CSF1 colony stimulating factor 1 (macrophage)
CSMD2 CUB and Sushi multiple domains 2
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
CYBA cytochrome b-245, alpha polypeptide
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DENND3 DENN/MADD domain containing 3
DENND6B DENN/MADD domain containing 6B
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DNAH8 dynein, axonemal, heavy chain 8
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DVL2 dishevelled segment polarity protein 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNLRB1 dynein, light chain, roadblock-type 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
ELP4 elongator acetyltransferase complex subunit 4
EP400 E1A binding protein p400
EPC1 enhancer of polycomb homolog 1 (Drosophila)
ERBB2IP erbb2 interacting protein
ERCC6L2 excision repair cross-complementation group 6-like 2
ERP44 endoplasmic reticulum protein 44
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
ETV3 ets variant 3
ETV6 ets variant 6
EXOSC1 exosome component 1
FAF2 Fas associated factor family member 2
FAM117B family with sequence similarity 117, member B
FANCM Fanconi anemia, complementation group M
FASTKD1 FAST kinase domains 1
FERMT3 fermitin family member 3
FLNA filamin A, alpha
FN1 fibronectin 1
FOSL2 FOS-like antigen 2
FOXC2 forkhead box C2
FRMD6 FERM domain containing 6
FRMPD4 FERM and PDZ domain containing 4
FZD1 frizzled class receptor 1
FZD10 frizzled class receptor 10
FZD2 frizzled class receptor 2
FZD3 frizzled class receptor 3
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
FZD6 frizzled class receptor 6
FZD7 frizzled class receptor 7
FZD8 frizzled class receptor 8
FZD9 frizzled class receptor 9
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GEMIN5 gem (nuclear organelle) associated protein 5
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPR158 G protein-coupled receptor 158
GSK3B glycogen synthase kinase 3 beta
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H1FX H1 histone family, member X
H2AFZ H2A histone family, member Z
H3F3A H3 histone, family 3A
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCFC2 host cell factor C2
HDAC1 histone deacetylase 1
HIRA histone cell cycle regulator
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST1H2AB histone cluster 1, H2ab
HIST1H2BB histone cluster 1, H2bb
HIST1H2BM histone cluster 1, H2bm
HIST1H4F histone cluster 1, H4f
HIST3H3 histone cluster 3, H3
HK1 hexokinase 1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOXA10 homeobox A10
HOXB5 homeobox B5
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSPB1 heat shock 27kDa protein 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL16 interleukin 16
IL1B interleukin 1, beta
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IMMT inner membrane protein, mitochondrial
INSM1 insulinoma-associated 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JUN jun proto-oncogene
KALRN kalirin, RhoGEF kinase
KANK2 KN motif and ankyrin repeat domains 2
KARS lysyl-tRNA synthetase
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0319 KIAA0319
KIAA0922 KIAA0922
KIAA2026 KIAA2026
KIF12 kinesin family member 12
KIF20B kinesin family member 20B
KLF10 Kruppel-like factor 10
KMT2A lysine (K)-specific methyltransferase 2A
KRI1 KRI1 homolog (S. cerevisiae)
LAS1L LAS1-like (S. cerevisiae)
LBX2 ladybird homeobox 2
LCN12 lipocalin 12
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS7B lectin, galactoside-binding, soluble, 7B
LIMS1 LIM and senescent cell antigen-like domains 1
LOX lysyl oxidase
LRP1B low density lipoprotein receptor-related protein 1B
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LTV1 LTV1 ribosome biogenesis factor
LUZP1 leucine zipper protein 1
MAATS1 MYCBP-associated, testis expressed 1
MAGEB10 melanoma antigen family B10
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP1A microtubule-associated protein 1A
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP7D1 MAP7 domain containing 1
MAST4 microtubule associated serine/threonine kinase family member 4
MATN4 matrilin 4
MAX MYC associated factor X
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MCM4 minichromosome maintenance complex component 4
MCTP2 multiple C2 domains, transmembrane 2
MED12L mediator complex subunit 12-like
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKL1 megakaryoblastic leukemia (translocation) 1
MOV10 Mov10 RISC complex RNA helicase
MRGBP MRG/MORF4L binding protein
MRPL14 mitochondrial ribosomal protein L14
MTRF1 mitochondrial translational release factor 1
MUC3A mucin 3A, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO18A myosin XVIIIA
MYO1D myosin ID
NAIP NLR family, apoptosis inhibitory protein
NAV3 neuron navigator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFIL3 nuclear factor, interleukin 3 regulated
NOA1 nitric oxide associated 1
NOMO2 NODAL modulator 2
NPC1L1 NPC1-like 1
NPR1 natriuretic peptide receptor 1
NPTX2 neuronal pentraxin II
NRD1 nardilysin (N-arginine dibasic convertase)
NUCLEOLIN nucleolin multifunctional protein
NUMA1 nuclear mitotic apparatus protein 1
NUP98 nucleoporin 98kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPHN1 oligophrenin 1
OTUD4 OTU deubiquitinase 4
PABPC1 poly(A) binding protein, cytoplasmic 1
PADI2 peptidyl arginine deiminase, type II
PALD1 phosphatase domain containing, paladin 1
PCBP2 poly(rC) binding protein 2
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDLIM4 PDZ and LIM domain 4
PDS5B PDS5 cohesin associated factor B
PFDN2 prefoldin subunit 2
PGD phosphogluconate dehydrogenase
PHC2 polyhomeotic homolog 2 (Drosophila)
PHF20 PHD finger protein 20
PHF6 PHD finger protein 6
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PITX2 paired-like homeodomain 2
PKM pyruvate kinase, muscle
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PML promyelocytic leukemia
POLG polymerase (DNA directed), gamma
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPA2 pyrophosphatase (inorganic) 2
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRG4 proteoglycan 4
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCDBP protein kinase C, delta binding protein
PRR11 proline rich 11
PRRC2A proline-rich coiled-coil 2A
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTBP1 polypyrimidine tract binding protein 1
QPCTL glutaminyl-peptide cyclotransferase-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAG1 recombination activating gene 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBFA ribosome binding factor A (putative)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM10 RNA binding motif protein 10
RBM39 RNA binding motif protein 39
RFX7 regulatory factor X, 7
RGAG1 retrotransposon gag domain containing 1
RIMS2 regulating synaptic membrane exocytosis 2
RING1 ring finger protein 1
RNF2 ring finger protein 2
RPL26L1 ribosomal protein L26-like 1
RPP30 ribonuclease P/MRP 30kDa subunit
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS16 ribosomal protein S16
RPS2 ribosomal protein S2
RPS21 ribosomal protein S21
RPS27L ribosomal protein S27-like
RRM1 ribonucleotide reductase M1
RRP1B ribosomal RNA processing 1B
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SACS sacsin molecular chaperone
SAMD9L sterile alpha motif domain containing 9-like
SBNO2 strawberry notch homolog 2 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SDF4 stromal cell derived factor 4
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC11C SEC11 homolog C (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETX senataxin
SFN stratifin
SGOL2 shugoshin-like 2 (S. pombe)
SH3GL2 SH3-domain GRB2-like 2
SH3RF1 SH3 domain containing ring finger 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHE Src homology 2 domain containing E
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC6 structural maintenance of chromosomes 6
SMTN smoothelin
SMYD4 SET and MYND domain containing 4
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPF small nuclear ribonucleoprotein polypeptide F
SNX19 sorting nexin 19
SQRDL sulfide quinone reductase-like (yeast)
SSB Sjogren syndrome antigen B (autoantigen La)
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
SUCLG1 succinate-CoA ligase, alpha subunit
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TBL2 transducin (beta)-like 2
TDG thymine-DNA glycosylase
TENM2 teneurin transmembrane protein 2
TEX2 testis expressed 2
TK1 thymidine kinase 1, soluble
TMPRSS11A transmembrane protease, serine 11A
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNPO1 transportin 1
TNR tenascin R
TNS2 tensin 2
TOPAZ1 testis and ovary specific PAZ domain containing 1
TPH1 tryptophan hydroxylase 1
TPP1 tripeptidyl peptidase I
TRABD2A TraB domain containing 2A
TRAK1 trafficking protein, kinesin binding 1
TRAP1 TNF receptor-associated protein 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRRAP transformation/transcription domain-associated protein
TUBA4A tubulin, alpha 4a
TUBB3 tubulin, beta 3 class III
TUBB6 tubulin, beta 6 class V
TUFM Tu translation elongation factor, mitochondrial
TXN thioredoxin
UBA1 ubiquitin-like modifier activating enzyme 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBE2O ubiquitin-conjugating enzyme E2O
UBTF upstream binding transcription factor, RNA polymerase I
ULK2 unc-51 like autophagy activating kinase 2
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
USP10 ubiquitin specific peptidase 10
USP36 ubiquitin specific peptidase 36
USP48 ubiquitin specific peptidase 48
WDFY3 WD repeat and FYVE domain containing 3
WIPF1 WAS/WASL interacting protein family, member 1
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT11 wingless-type MMTV integration site family, member 11
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B
WNT8A wingless-type MMTV integration site family, member 8A
WNT8B wingless-type MMTV integration site family, member 8B
WNT9A wingless-type MMTV integration site family, member 9A
WNT9B wingless-type MMTV integration site family, member 9B
XKRX XK, Kell blood group complex subunit-related, X-linked
XYLT1 xylosyltransferase I
YAF2 YY1 associated factor 2
YBX1 Y box binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB18 zinc finger and BTB domain containing 18
ZBTB40 zinc finger and BTB domain containing 40
ZC3H18 zinc finger CCCH-type containing 18
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX3 zinc finger homeobox 3
ZMYM4 zinc finger, MYM-type 4
ZNF106 zinc finger protein 106
ZNF33A zinc finger protein 33A
ZNF33B zinc finger protein 33B
ZNF354B zinc finger protein 354B
ZNF541 zinc finger protein 541
ZNF586 zinc finger protein 586
ZNF703 zinc finger protein 703
ZNF740 zinc finger protein 740
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1