DAP Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description death-associated protein|This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 1611)
External Link https://ncbi.nlm.nih.gov/gene/1611
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Genes

499 genes differentially expressed following the DAP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CDCA4 cell division cycle associated 4 0.0105272
LRRC17 leucine rich repeat containing 17 0.00877126
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00867462
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00845296
PRDX2 peroxiredoxin 2 0.00833276
AK4 adenylate kinase 4 0.00729438
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00729416
PTN pleiotrophin 0.00724324
FGFR3 fibroblast growth factor receptor 3 0.00704515
GATA3 GATA binding protein 3 0.00695907
CTSH cathepsin H 0.0068049
SSBP2 single-stranded DNA binding protein 2 0.00670532
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00648013
KIF20A kinesin family member 20A 0.00633321
DMAC2L distal membrane arm assembly component 2 like 0.00624779
MSMO1 methylsterol monooxygenase 1 0.00618751
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00618532
KCTD12 potassium channel tetramerization domain containing 12 0.00616923
FABP1 fatty acid binding protein 1, liver 0.00597794
NXT2 nuclear transport factor 2-like export factor 2 0.00594966
GPC3 glypican 3 0.00591351
BHLHE41 basic helix-loop-helix family, member e41 0.00586024
MYBPC1 myosin binding protein C, slow type 0.00580628
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00580203
GLUL glutamate-ammonia ligase 0.0057816
CDC42 cell division cycle 42 0.00577575
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00576081
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00571686
EGR2 early growth response 2 0.00570371
EIF5 eukaryotic translation initiation factor 5 0.00567634
SPON1 spondin 1, extracellular matrix protein 0.00560647
HMGB3 high mobility group box 3 0.00559199
HAT1 histone acetyltransferase 1 0.00554509
MECOM MDS1 and EVI1 complex locus 0.00554083
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00551381
MRPS30 mitochondrial ribosomal protein S30 0.00550417
CCNF cyclin F 0.00550327
DCXR dicarbonyl/L-xylulose reductase 0.00550323
SEPP1 selenoprotein P, plasma, 1 0.00547866
COL1A2 collagen, type I, alpha 2 0.00547595
ECI2 enoyl-CoA delta isomerase 2 0.00545062
RBBP8 retinoblastoma binding protein 8 0.00544975
MED28 mediator complex subunit 28 0.00544427
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00541902
TRMT5 tRNA methyltransferase 5 0.00540334
BIRC5 baculoviral IAP repeat containing 5 0.00539718
RPA3 replication protein A3, 14kDa 0.00539671
PRKD3 protein kinase D3 0.00533677
GSTT1 glutathione S-transferase theta 1 0.0053112
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00528568
XK X-linked Kx blood group 0.00527916
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00525275
LGALS3 lectin, galactoside-binding, soluble, 3 0.00520395
HSDL2 hydroxysteroid dehydrogenase like 2 0.0051878
ASRGL1 asparaginase like 1 0.00518434
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00518013
PRPF4 pre-mRNA processing factor 4 0.00512694
ACAT2 acetyl-CoA acetyltransferase 2 0.00510206
DOK5 docking protein 5 0.00509891
MPZL2 myelin protein zero-like 2 0.00507699
MATN2 matrilin 2 0.00507587
RPIA ribose 5-phosphate isomerase A 0.00506927
CFI complement factor I 0.00506627
POSTN periostin, osteoblast specific factor 0.00505632
FBXO5 F-box protein 5 0.00501417
SORD sorbitol dehydrogenase 0.00500373
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00500372
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.0049906
SPC25 SPC25, NDC80 kinetochore complex component 0.00498381
RFC3 replication factor C (activator 1) 3, 38kDa 0.00497356
FUCA1 fucosidase, alpha-L- 1, tissue 0.00496413
METTL7A methyltransferase like 7A 0.0049583
RESF1 retroelement silencing factor 1 0.00494657
CHEK2 checkpoint kinase 2 0.00493334
CCNB2 cyclin B2 0.00493185
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00493163
ASF1B anti-silencing function 1B histone chaperone 0.00489894
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00487297
MRPL17 mitochondrial ribosomal protein L17 0.00486891
PAK1IP1 PAK1 interacting protein 1 0.00479406
ARMT1 acidic residue methyltransferase 1 0.00477199
PLK1 polo-like kinase 1 0.00476148
COL3A1 collagen, type III, alpha 1 0.00475396
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00472018
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00470608
IFITM1 interferon induced transmembrane protein 1 0.00469884
SPRED2 sprouty-related, EVH1 domain containing 2 0.00467824
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00466968
ZNF443 zinc finger protein 443 0.00464934
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00463902
SQLE squalene epoxidase 0.00462464
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00462061
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00462043
MRPL20 mitochondrial ribosomal protein L20 0.00460832
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00459677
FTO fat mass and obesity associated 0.00453017
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00452219
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00451618
RBBP4 retinoblastoma binding protein 4 0.00451274
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00450318
GIMAP6 GTPase, IMAP family member 6 0.00448877
FGF13 fibroblast growth factor 13 0.00448779
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00448656
HMGN2 high mobility group nucleosomal binding domain 2 0.00448153
LMNB1 lamin B1 0.0044762
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.00447077
OLFM1 olfactomedin 1 0.00443716
ANOS1 anosmin 1 0.00440736
LIG1 ligase I, DNA, ATP-dependent 0.00440487
RANBP1 RAN binding protein 1 0.00439002
RPA2 replication protein A2, 32kDa 0.00435795
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00435243
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00432644
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00432036
LTBP1 latent transforming growth factor beta binding protein 1 0.00430959
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00430357
KANSL2 KAT8 regulatory NSL complex subunit 2 0.00429857
ADIRF adipogenesis regulatory factor 0.00428487
MARCKSL1 MARCKS-like 1 0.00427684
ATF1 activating transcription factor 1 0.00426315
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00426235
LIPT1 lipoyltransferase 1 0.00422844
PPA2 pyrophosphatase (inorganic) 2 0.00421541
THYN1 thymocyte nuclear protein 1 0.00420393
AKAP7 A kinase (PRKA) anchor protein 7 0.00420349
RAB40B RAB40B, member RAS oncogene family 0.00420153
TMEM70 transmembrane protein 70 0.00418237
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00416342
NID1 nidogen 1 0.00416141
FEN1 flap structure-specific endonuclease 1 0.0041574
CD99 CD99 molecule 0.00415484
VRK1 vaccinia related kinase 1 0.00415216
IPO5 importin 5 0.0041322
AURKA aurora kinase A 0.00412545
RRM1 ribonucleotide reductase M1 0.00412296
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00412039
ADI1 acireductone dioxygenase 1 0.00412004
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0041091
SEPHS1 selenophosphate synthetase 1 0.00410622
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.00410527
APOM apolipoprotein M 0.00410236
RNASEH2A ribonuclease H2, subunit A 0.0040911
G0S2 G0/G1 switch 2 0.00408938
UBE2N ubiquitin-conjugating enzyme E2N 0.0040887
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00408797
SPAG16 sperm associated antigen 16 0.00408516
OIP5 Opa interacting protein 5 0.00408348
CCNA2 cyclin A2 0.00408163
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00407967
PPAT phosphoribosyl pyrophosphate amidotransferase 0.0040753
CD93 CD93 molecule 0.00407222
CDC45 cell division cycle 45 0.0040699
ALCAM activated leukocyte cell adhesion molecule 0.00405127
EPHA4 EPH receptor A4 0.00404331
DDHD2 DDHD domain containing 2 0.00403097
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.00402417
LYZ lysozyme 0.00402036
CDK1 cyclin-dependent kinase 1 0.00401948
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00401241
IFITM2 interferon induced transmembrane protein 2 0.00401009
LSM1 LSM1, U6 small nuclear RNA associated 0.00400582
TMEM168 transmembrane protein 168 0.00400441
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00400083
UFL1 UFM1-specific ligase 1 0.00399766
SPRY2 sprouty homolog 2 (Drosophila) 0.00399688
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00399143
RGS13 regulator of G-protein signaling 13 0.00398859
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00398481
TTK TTK protein kinase 0.00397747
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00397202
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.00397078
CFH complement factor H 0.0039683
LEPR leptin receptor 0.0039666
UBE2C ubiquitin-conjugating enzyme E2C 0.00396104
GLRX5 glutaredoxin 5 0.00396022
PPP1R8 protein phosphatase 1, regulatory subunit 8 0.00395871
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.00395699
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00395633
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00395392
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00394719
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0039432
MSH2 mutS homolog 2 0.00394132
ERLIN2 ER lipid raft associated 2 0.00393762
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00393706
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00393271
PPARG peroxisome proliferator-activated receptor gamma 0.00392835
DHCR7 7-dehydrocholesterol reductase 0.0039234
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00392305
GANAB glucosidase, alpha; neutral AB 0.00391721
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00391568
TPGS2 tubulin polyglutamylase complex subunit 2 0.00390876
SET SET nuclear proto-oncogene 0.00390551
BARD1 BRCA1 associated RING domain 1 0.00390392
NDC80 NDC80 kinetochore complex component 0.00389871
CD302 CD302 molecule 0.00389589
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.00389455
SERBP1 SERPINE1 mRNA binding protein 1 0.00389134
MCM3 minichromosome maintenance complex component 3 0.00389037
PUS3 pseudouridylate synthase 3 0.00389014
LDB2 LIM domain binding 2 0.00388663
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00388061
FZD5 frizzled class receptor 5 0.00387102
INSIG1 insulin induced gene 1 0.00386554
PARPBP PARP1 binding protein 0.00386245
HNMT histamine N-methyltransferase 0.00386124
AQP4 aquaporin 4 0.00386011
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.00385848
PRDX4 peroxiredoxin 4 0.00385354
SLBP stem-loop binding protein 0.0038496
CTSZ cathepsin Z 0.00384371
HIC2 hypermethylated in cancer 2 0.00384312
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00383194
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00383127
NPAS3 neuronal PAS domain protein 3 0.0038267
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00382131
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00382014
PCLAF PCNA clamp associated factor 0.00381748
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.00381452
BAG4 BCL2-associated athanogene 4 0.00381425
CBX3 chromobox homolog 3 0.00380945
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00380795
ANAPC15 anaphase promoting complex subunit 15 0.00379933
NPTX2 neuronal pentraxin II 0.00379806
VBP1 von Hippel-Lindau binding protein 1 0.00379111
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00378331
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.00377765
FASTKD3 FAST kinase domains 3 0.0037747
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00377408
NCAPH non-SMC condensin I complex, subunit H 0.00377103
EPS8 epidermal growth factor receptor pathway substrate 8 0.00376829
TRAPPC4 trafficking protein particle complex 4 0.00376441
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00376246
METTL18 methyltransferase like 18 0.00375767
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.00375694
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.00375287
CDKN3 cyclin-dependent kinase inhibitor 3 0.0037513
NXT1 nuclear transport factor 2-like export factor 1 0.00374696
KIF18A kinesin family member 18A 0.00373607
NES nestin 0.00373239
NRGN neurogranin (protein kinase C substrate, RC3) 0.00373076
PSIP1 PC4 and SFRS1 interacting protein 1 0.00372919
PBK PDZ binding kinase 0.00372449
THAP12 THAP domain containing 12 0.00372284
COPS4 COP9 signalosome subunit 4 0.00372246
CTR9 CTR9, Paf1/RNA polymerase II complex component 0.00372162
C2CD5 C2 calcium-dependent domain containing 5 0.00371865
LBR lamin B receptor 0.003718
B3GNT1 0.00371398
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00370691
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00370033

decreased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 -0.0123382
S100A8 S100 calcium binding protein A8 -0.0120782
PDZK1IP1 PDZK1 interacting protein 1 -0.011261
S100A9 S100 calcium binding protein A9 -0.0111765
KRT7 keratin 7, type II -0.00996109
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00914986
APOD apolipoprotein D -0.00889827
CRISP3 cysteine-rich secretory protein 3 -0.00877745
GREM1 gremlin 1, DAN family BMP antagonist -0.00876601
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00864123
SLPI secretory leukocyte peptidase inhibitor -0.00856736
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00837609
MAP7 microtubule-associated protein 7 -0.0081273
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00811663
PERP PERP, TP53 apoptosis effector -0.00809318
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00805955
MVP major vault protein -0.00796696
HMOX1 heme oxygenase 1 -0.00785798
TFPI2 tissue factor pathway inhibitor 2 -0.0078456
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00774256
TSPO translocator protein (18kDa) -0.00754858
S100A7 S100 calcium binding protein A7 -0.00752725
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00746524
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00744508
CD37 CD37 molecule -0.00737009
IRS2 insulin receptor substrate 2 -0.00733886
TM4SF1 transmembrane 4 L six family member 1 -0.00709457
IL32 interleukin 32 -0.00708411
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00699926
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00699818
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00697967
BMP4 bone morphogenetic protein 4 -0.00693734
MINK1 misshapen-like kinase 1 -0.00679571
CNPY3 canopy FGF signaling regulator 3 -0.00671084
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00667879
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00667834
PI3 peptidase inhibitor 3, skin-derived -0.00666603
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00652694
MCOLN1 mucolipin 1 -0.00648169
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00641908
STXBP2 syntaxin binding protein 2 -0.00639971
COBL cordon-bleu WH2 repeat protein -0.00631798
SIK1 salt-inducible kinase 1 -0.00626176
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00625429
KLK10 kallikrein-related peptidase 10 -0.00615806
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00607972
MCM2 minichromosome maintenance complex component 2 -0.00607767
RHCG Rh family, C glycoprotein -0.0060064
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00599747
MFAP5 microfibrillar associated protein 5 -0.00598887
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00598405
TYMP thymidine phosphorylase -0.00598039
GLS glutaminase -0.00591735
TUBB6 tubulin, beta 6 class V -0.00582559
DUSP1 dual specificity phosphatase 1 -0.00582517
GRB7 growth factor receptor-bound protein 7 -0.00577593
RRAGD Ras-related GTP binding D -0.00574607
CFB complement factor B -0.00572678
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00571417
ACADVL acyl-CoA dehydrogenase, very long chain -0.00570745
PLK2 polo-like kinase 2 -0.00570644
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00568094
TRIM16 tripartite motif containing 16 -0.00567281
ACTN4 actinin, alpha 4 -0.00566975
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00565962
AMOTL2 angiomotin like 2 -0.00563668
TLE5 TLE family member 5, transcriptional modulator -0.00563457
HSPB8 heat shock 22kDa protein 8 -0.00561632
FBXW12 F-box and WD repeat domain containing 12 -0.00561231
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00559184
SPRR2B small proline-rich protein 2B -0.00556802
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00552486
CHGB chromogranin B -0.00549613
CD4 CD4 molecule -0.00548842
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00548497
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -0.00545091
DGKA diacylglycerol kinase, alpha 80kDa -0.00544571
TCF4 transcription factor 4 -0.00541938
PROM1 prominin 1 -0.00541421
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00540197
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00535543
KLK11 kallikrein-related peptidase 11 -0.0053518
ZNF160 zinc finger protein 160 -0.00533771
AQP3 aquaporin 3 (Gill blood group) -0.0053329
ZC3H12A zinc finger CCCH-type containing 12A -0.00531605
IPO13 importin 13 -0.00530675
OSBPL10 oxysterol binding protein-like 10 -0.00527144
EPHA2 EPH receptor A2 -0.00524648
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00522604
RABAC1 Rab acceptor 1 (prenylated) -0.00519073
KRT6A keratin 6A, type II -0.0051857
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00516983
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00515294
KLHL24 kelch-like family member 24 -0.00512707
JUNB jun B proto-oncogene -0.00510985
KRT6B keratin 6B, type II -0.00506979
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00505634
SOD2 superoxide dismutase 2, mitochondrial -0.00505186
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00503629
TPD52L1 tumor protein D52-like 1 -0.00499929
CST1 cystatin SN -0.00499793
AKAP9 A kinase (PRKA) anchor protein 9 -0.0049878
XIC X chromosome inactivation center -0.0049809
SPATA20 spermatogenesis associated 20 -0.0049616
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.00495281
HSPA2 heat shock 70kDa protein 2 -0.00493878
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00492578
CLDN4 claudin 4 -0.00492218
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.00491175
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00490904
CALCOCO1 calcium binding and coiled-coil domain 1 -0.00490862
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -0.00490542
KLF6 Kruppel-like factor 6 -0.00488414
STK10 serine/threonine kinase 10 -0.0048795
LAMC2 laminin, gamma 2 -0.00485527
EFNA1 ephrin-A1 -0.00485276
CLIP2 CAP-GLY domain containing linker protein 2 -0.0048502
PLCB4 phospholipase C, beta 4 -0.00484931
RNF167 ring finger protein 167 -0.00484526
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0048413
H1-10 H1.10 linker histone -0.00482681
LYPD3 LY6/PLAUR domain containing 3 -0.00482519
PILRB paired immunoglobin-like type 2 receptor beta -0.00482353
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.0048081
MAP7D1 MAP7 domain containing 1 -0.00479412
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00478618
ECM1 extracellular matrix protein 1 -0.00478
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -0.00477852
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -0.00476746
INSM1 insulinoma-associated 1 -0.00475137
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00474115
LRRC8D leucine rich repeat containing 8 family, member D -0.00468747
RRBP1 ribosome binding protein 1 -0.00466133
PMP22 peripheral myelin protein 22 -0.00465827
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00465638
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00464951
S100A11 S100 calcium binding protein A11 -0.00464616
HSPA1A heat shock 70kDa protein 1A -0.00464594
WFDC1 WAP four-disulfide core domain 1 -0.00462654
COL9A2 collagen, type IX, alpha 2 -0.00461148
MLXIP MLX interacting protein -0.00460355
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00460219
GTPBP2 GTP binding protein 2 -0.00460206
CRYAB crystallin, alpha B -0.00459869
SGK1 serum/glucocorticoid regulated kinase 1 -0.0045752
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00456895
YBX3 Y box binding protein 3 -0.00456557
KRT16 keratin 16, type I -0.00455852
NPC1 Niemann-Pick disease, type C1 -0.00453697
JAG1 jagged 1 -0.00453578
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00453296
PLXNB2 plexin B2 -0.00452089
LITAF lipopolysaccharide-induced TNF factor -0.00451894
SPRR1B small proline-rich protein 1B -0.00451306
PTPRK protein tyrosine phosphatase, receptor type, K -0.00450453
CLCN7 chloride channel, voltage-sensitive 7 -0.00448378
PRUNE2 prune homolog 2 (Drosophila) -0.00447338
ARMCX1 armadillo repeat containing, X-linked 1 -0.00447021
PKD2 polycystic kidney disease 2 (autosomal dominant) -0.00446707
MYH9 myosin, heavy chain 9, non-muscle -0.00446487
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00445624
NOTCH2NL notch 2 N-terminal like -0.00443891
STATH statherin -0.00443676
TNIP1 TNFAIP3 interacting protein 1 -0.00443038
INAVA innate immunity activator -0.00442204
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -0.00441483
P3H2 prolyl 3-hydroxylase 2 -0.00441191
TMEM45A transmembrane protein 45A -0.00437806
ADGRE5 adhesion G protein-coupled receptor E5 -0.00436529
NRCAM neuronal cell adhesion molecule -0.00436365
SFXN3 sideroflexin 3 -0.00436111
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00436106
STX4 syntaxin 4 -0.00435774
CUX1 cut-like homeobox 1 -0.00435456
SPRR1A small proline-rich protein 1A -0.00435206
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00434102
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00432189
ZNF721 zinc finger protein 721 -0.00429843
FCGBP Fc fragment of IgG binding protein -0.00429595
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00429586
ASS1 argininosuccinate synthase 1 -0.00428308
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00428152
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00428071
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00427373
NBEAL2 neurobeachin-like 2 -0.00427061
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00425583
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00425162
CORO1A coronin, actin binding protein, 1A -0.00424261
POR P450 (cytochrome) oxidoreductase -0.00423713
DUSP10 dual specificity phosphatase 10 -0.00421955
CCN2 cellular communication network factor 2 -0.00420588
RBPMS RNA binding protein with multiple splicing -0.00420564
NDRG1 N-myc downstream regulated 1 -0.00420547
FGF9 fibroblast growth factor 9 -0.00420238
KLF4 Kruppel-like factor 4 (gut) -0.00419409
CCND3 cyclin D3 -0.00419049
ORAI3 ORAI calcium release-activated calcium modulator 3 -0.00418632
THBS3 thrombospondin 3 -0.00418364
BAG3 BCL2-associated athanogene 3 -0.00416737
GOLGA8A golgin A8 family, member A -0.00416075
DSP desmoplakin -0.00414788
CAPN3 calpain 3, (p94) -0.00414701
ADM adrenomedullin -0.00414076
ADGRG1 adhesion G protein-coupled receptor G1 -0.00413933
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00413728
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00413457
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00412845
HSPB1 heat shock 27kDa protein 1 -0.00411901
DSG3 desmoglein 3 -0.00411525
CSF3R colony stimulating factor 3 receptor (granulocyte) -0.00411337
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00410968
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00410217
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00409465
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00408998
PNPLA6 patatin-like phospholipase domain containing 6 -0.00408834
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00408565
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00407938
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00407619
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -0.00407259
KRT81 keratin 81, type II -0.00407209
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00407208
FAM193B family with sequence similarity 193, member B -0.00406481
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -0.00406121
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00405409
RTN2 reticulon 2 -0.00405319
SPRR3 small proline-rich protein 3 -0.00403531
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00401963
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00401534
LYST lysosomal trafficking regulator -0.00400866
BIRC7 baculoviral IAP repeat containing 7 -0.00400487
PYGB phosphorylase, glycogen; brain -0.00399946
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00399367
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -0.00399316
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00399151
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00398678
PCDH9 protocadherin 9 -0.00398327
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -0.00397259
ETHE1 ethylmalonic encephalopathy 1 -0.00397128
MAGEA3 melanoma antigen family A3 -0.00395902
BEX4 brain expressed, X-linked 4 -0.00395839
SORBS2 sorbin and SH3 domain containing 2 -0.00395593
REXO2 RNA exonuclease 2 -0.00395187
RUNX3 runt-related transcription factor 3 -0.00394959
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00394526
FILIP1L filamin A interacting protein 1-like -0.0039444
SQSTM1 sequestosome 1 -0.00394104
PFKP phosphofructokinase, platelet -0.00394002
OGA O-GlcNAcase -0.00393127
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00392538