DAP3 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description death associated protein 3|Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 7818)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DAP3
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Genes

300 co-expressed genes for DAP3 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACLY ATP citrate lyase
AFG3L2 AFG3-like AAA ATPase 2
AHCYL1 adenosylhomocysteinase-like 1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ANAPC5 anaphase promoting complex subunit 5
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATG5 autophagy related 5
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATXN10 ataxin 10
BAG6 BCL2-associated athanogene 6
BANF1 barrier to autointegration factor 1
BRD3 bromodomain containing 3
BRD8 bromodomain containing 8
BTF3 basic transcription factor 3
BUB3 BUB3 mitotic checkpoint protein
C14ORF166 chromosome 14 open reading frame 166
C21ORF33 chromosome 21 open reading frame 33
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CANX calnexin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CBX3 chromobox homolog 3
CCDC59 coiled-coil domain containing 59
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDV3 CDV3 homolog (mouse)
CLNS1A chloride channel, nucleotide-sensitive, 1A
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNOT7 CCR4-NOT transcription complex, subunit 7
COMMD3 COMM domain containing 3
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5B cytochrome c oxidase subunit Vb
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
COX7B cytochrome c oxidase subunit VIIb
COX7C cytochrome c oxidase subunit VIIc
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CS citrate synthase
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CYC1 cytochrome c-1
DAP3 death associated protein 3
DDB1 damage-specific DNA binding protein 1, 127kDa
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDT D-dopachrome tautomerase
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEK DEK proto-oncogene
DGUOK deoxyguanosine kinase
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DNPEP aspartyl aminopeptidase
DRG1 developmentally regulated GTP binding protein 1
DYNLL1 dynein, light chain, LC8-type 1
EBP emopamil binding protein (sterol isomerase)
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4A2 eukaryotic translation initiation factor 4A2
EIF6 eukaryotic translation initiation factor 6
EPRS glutamyl-prolyl-tRNA synthetase
EXOSC8 exosome component 8
FAM120A family with sequence similarity 120A
FBL fibrillarin
FBXW11 F-box and WD repeat domain containing 11
FDPS farnesyl diphosphate synthase
FIBP fibroblast growth factor (acidic) intracellular binding protein
GANAB glucosidase, alpha; neutral AB
GBAS glioblastoma amplified sequence
GDI2 GDP dissociation inhibitor 2
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPN1 GPN-loop GTPase 1
GTF3A general transcription factor IIIA
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAX1 HCLS1 associated protein X-1
HDAC1 histone deacetylase 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA14 heat shock 70kDa protein 14
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFRD1 interferon-related developmental regulator 1
IK IK cytokine, down-regulator of HLA II
ILF2 interleukin enhancer binding factor 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INTS8 integrator complex subunit 8
JTB jumping translocation breakpoint
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MDH1 malate dehydrogenase 1, NAD (soluble)
METAP1 methionyl aminopeptidase 1
MRPL23 mitochondrial ribosomal protein L23
MRPL9 mitochondrial ribosomal protein L9
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
NAP1L4 nucleosome assembly protein 1-like 4
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NCL nucleolin
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NELFB negative elongation factor complex member B
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NOL11 nucleolar protein 11
NONO non-POU domain containing, octamer-binding
NRD1 nardilysin (N-arginine dibasic convertase)
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NUP188 nucleoporin 188kDa
OXA1L oxidase (cytochrome c) assembly 1-like
PAPOLA poly(A) polymerase alpha
PARK7 parkinson protein 7
PDAP1 PDGFA associated protein 1
PDHB pyruvate dehydrogenase (lipoamide) beta
PGK1 phosphoglycerate kinase 1
PHB2 prohibitin 2
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PNRC2 proline-rich nuclear receptor coactivator 2
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP6C protein phosphatase 6, catalytic subunit
PRICKLE4 prickle homolog 4 (Drosophila)
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTBP1 polypyrimidine tract binding protein 1
PTMA prothymosin, alpha
PUF60 poly-U binding splicing factor 60KDa
PUM2 pumilio RNA-binding family member 2
QARS glutaminyl-tRNA synthetase
RALY RALY heterogeneous nuclear ribonucleoprotein
RAN RAN, member RAS oncogene family
RBM15 RNA binding motif protein 15
RBMX RNA binding motif protein, X-linked
RHEB Ras homolog enriched in brain
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RPL12 ribosomal protein L12
RPL13A ribosomal protein L13a
RPL14 ribosomal protein L14
RPL17 ribosomal protein L17
RPL19 ribosomal protein L19
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL3 ribosomal protein L3
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL35A ribosomal protein L35a
RPL37 ribosomal protein L37
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPL39 ribosomal protein L39
RPL4 ribosomal protein L4
RPL41 ribosomal protein L41
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL9 ribosomal protein L9
RPN2 ribophorin II
RPP40 ribonuclease P/MRP 40kDa subunit
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS2 ribosomal protein S2
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS28 ribosomal protein S28
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPSA ribosomal protein SA
RUVBL2 RuvB-like AAA ATPase 2
RWDD1 RWD domain containing 1
SARS seryl-tRNA synthetase
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC61B Sec61 beta subunit
SERP1 stress-associated endoplasmic reticulum protein 1
SET SET nuclear proto-oncogene
SETD3 SET domain containing 3
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMNDC1 survival motor neuron domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SP3 Sp3 transcription factor
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP19 signal recognition particle 19kDa
SRP72 signal recognition particle 72kDa
SRP9 signal recognition particle 9kDa
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
SRSF9 serine/arginine-rich splicing factor 9
SSR2 signal sequence receptor, beta (translocon-associated protein beta)
STARD7 StAR-related lipid transfer (START) domain containing 7
STOML2 stomatin (EPB72)-like 2
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TARDBP TAR DNA binding protein
TBCB tubulin folding cofactor B
TBL3 transducin (beta)-like 3
TCEA1 transcription elongation factor A (SII), 1
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMEM147 transmembrane protein 147
TRA2B transformer 2 beta homolog (Drosophila)
TRAPPC3 trafficking protein particle complex 3
TUFM Tu translation elongation factor, mitochondrial
TUG1 taurine up-regulated 1 (non-protein coding)
UBA1 ubiquitin-like modifier activating enzyme 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRH ubiquinol-cytochrome c reductase hinge protein
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
UXT ubiquitously-expressed, prefoldin-like chaperone
VDAC2 voltage-dependent anion channel 2
VGLL4 vestigial-like family member 4
XPO1 exportin 1
XPO7 exportin 7
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H15 zinc finger CCCH-type containing 15
ZNF146 zinc finger protein 146
ZNF207 zinc finger protein 207
ZNHIT3 zinc finger, HIT-type containing 3
ZPR1 ZPR1 zinc finger