DAPK1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description death-associated protein kinase 1|Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 1612)
External Link https://ncbi.nlm.nih.gov/gene/1612
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Genes

499 genes differentially expressed following the DAPK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RTN2 reticulon 2 0.0174461
OXA1L oxidase (cytochrome c) assembly 1-like 0.0149007
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0123759
MAGEA3 melanoma antigen family A3 0.0121309
CHGB chromogranin B 0.0116843
TTN titin 0.0116215
RFTN1 raftlin, lipid raft linker 1 0.011228
KLHL41 kelch-like family member 41 0.0110219
PCNA proliferating cell nuclear antigen 0.0107448
MYBPC1 myosin binding protein C, slow type 0.0106991
ACTA1 actin, alpha 1, skeletal muscle 0.0103101
PKM pyruvate kinase, muscle 0.0101407
CAPN3 calpain 3, (p94) 0.00987419
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00982988
ENO3 enolase 3 (beta, muscle) 0.00972406
CKM creatine kinase, muscle 0.00942235
IFI44L interferon-induced protein 44-like 0.00933881
APOD apolipoprotein D 0.00900876
TNNC1 troponin C type 1 (slow) 0.00890328
DUSP2 dual specificity phosphatase 2 0.00881211
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.00876903
TNNI1 troponin I type 1 (skeletal, slow) 0.00844527
MX1 MX dynamin-like GTPase 1 0.00825102
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00823798
TNNC2 troponin C type 2 (fast) 0.0081161
DUSP5 dual specificity phosphatase 5 0.00807957
ADM adrenomedullin 0.00795308
MELK maternal embryonic leucine zipper kinase 0.00788568
TUBA4A tubulin, alpha 4a 0.00786283
SIK1 salt-inducible kinase 1 0.00784824
SPRED2 sprouty-related, EVH1 domain containing 2 0.00774202
FABP7 fatty acid binding protein 7, brain 0.00773597
POPDC3 popeye domain containing 3 0.00770442
TNNT1 troponin T type 1 (skeletal, slow) 0.00765892
SLN sarcolipin 0.00765391
MVP major vault protein 0.0076279
LY6E lymphocyte antigen 6 complex, locus E 0.00760352
PDE4DIP phosphodiesterase 4D interacting protein 0.00756661
TPM3 tropomyosin 3 0.00755899
EREG epiregulin 0.00755843
VDAC1 voltage-dependent anion channel 1 0.00749523
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00742034
GUSBP3 glucuronidase, beta pseudogene 3 0.00738741
CXCL13 chemokine (C-X-C motif) ligand 13 0.0073769
MYOT myotilin 0.00734251
KLF6 Kruppel-like factor 6 0.00729546
ASS1 argininosuccinate synthase 1 0.00728889
PEG10 paternally expressed 10 0.00719623
CXCL10 chemokine (C-X-C motif) ligand 10 0.00711396
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00707827
UFM1 ubiquitin-fold modifier 1 0.00707493
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00703226
ACTN2 actinin, alpha 2 0.00702093
SMPX small muscle protein, X-linked 0.00697028
AK1 adenylate kinase 1 0.00694938
IL6R interleukin 6 receptor 0.00694688
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00694623
RHOBTB3 Rho-related BTB domain containing 3 0.00694325
ATF4 activating transcription factor 4 0.0068958
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.00679795
FSCN1 fascin actin-bundling protein 1 0.00679446
DMD dystrophin 0.00672127
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00671997
MYBPC2 myosin binding protein C, fast type 0.00671486
PLXNB2 plexin B2 0.00670624
MFSD10 major facilitator superfamily domain containing 10 0.00670582
YBX3 Y box binding protein 3 0.00667271
PFN2 profilin 2 0.00660438
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00660138
IER5 immediate early response 5 0.00657855
MAB21L1 mab-21-like 1 (C. elegans) 0.00656947
TENT5A terminal nucleotidyltransferase 5A 0.00656377
FGG fibrinogen gamma chain 0.00650899
HEATR1 HEAT repeat containing 1 0.00645352
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00643212
TPM2 tropomyosin 2 (beta) 0.00640624
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.00640122
SEPP1 selenoprotein P, plasma, 1 0.00637166
ACTN4 actinin, alpha 4 0.00635754
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00629863
RBM26 RNA binding motif protein 26 0.00629589
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00625003
ECM1 extracellular matrix protein 1 0.0062217
PLIN3 perilipin 3 0.0062073
HSPB3 heat shock 27kDa protein 3 0.00619407
DUSP10 dual specificity phosphatase 10 0.00616905
GPI glucose-6-phosphate isomerase 0.00616802
RNPS1 RNA binding protein S1, serine-rich domain 0.00616135
BIN1 bridging integrator 1 0.00614595
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.00610714
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.00609969
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0060995
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00609427
ACTC1 actin, alpha, cardiac muscle 1 0.00609187
CREG1 cellular repressor of E1A-stimulated genes 1 0.00607065
TFRC transferrin receptor 0.00606894
FASN fatty acid synthase 0.00605534
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.00605521
MAGEA12 melanoma antigen family A12 0.00603161
NEFM neurofilament, medium polypeptide 0.00602363
MAPK6 mitogen-activated protein kinase 6 0.00600548
CDC20 cell division cycle 20 0.00595393
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00591948
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.0059183
FKBP11 FK506 binding protein 11, 19 kDa 0.0058863
MYOZ2 myozenin 2 0.0058465
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00584439
SPATA20 spermatogenesis associated 20 0.00583415
DPP8 dipeptidyl-peptidase 8 0.00582838
LSP1 lymphocyte-specific protein 1 0.00580661
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00575486
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.00574767
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.00574325
CD99 CD99 molecule 0.00574063
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00573426
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00572034
NRN1 neuritin 1 0.00571916
OLFML2A olfactomedin-like 2A 0.00570742
TNNI2 troponin I type 2 (skeletal, fast) 0.00569481
MB myoglobin 0.00565155
RRAD Ras-related associated with diabetes 0.00564857
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.005634
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00561643
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00557956
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00557609
RABAC1 Rab acceptor 1 (prenylated) 0.00554787
TCF4 transcription factor 4 0.00552225
CTSG cathepsin G 0.00550495
TNNT3 troponin T type 3 (skeletal, fast) 0.00545298
SORBS3 sorbin and SH3 domain containing 3 0.00544188
LMNA lamin A/C 0.00541045
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00540752
KIAA0125 KIAA0125 0.00539552
GAS1 growth arrest-specific 1 0.00538819
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.00538449
DMPK dystrophia myotonica-protein kinase 0.00537739
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00537453
ATF3 activating transcription factor 3 0.00533927
COMT catechol-O-methyltransferase 0.00532935
C10ORF10 chromosome 10 open reading frame 10 0.0053281
MSRB2 methionine sulfoxide reductase B2 0.00532314
SETD5 SET domain containing 5 0.00530529
RAB1A RAB1A, member RAS oncogene family 0.00529113
PDLIM5 PDZ and LIM domain 5 0.00528896
RORA RAR-related orphan receptor A 0.00528165
GRAMD1B GRAM domain containing 1B 0.00527629
NVL nuclear VCP-like 0.0052729
SPRY4 sprouty homolog 4 (Drosophila) 0.00522511
ZEB2 zinc finger E-box binding homeobox 2 0.00522239
TDO2 tryptophan 2,3-dioxygenase 0.00519039
KLK5 kallikrein-related peptidase 5 0.00517733
IFI27 interferon, alpha-inducible protein 27 0.00515043
MYOZ1 myozenin 1 0.00514925
HMOX1 heme oxygenase 1 0.00513491
GADD45B growth arrest and DNA-damage-inducible, beta 0.00511563
LAD1 ladinin 1 0.00510251
LGALS9 lectin, galactoside-binding, soluble, 9 0.00510151
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00508594
MSRB1 methionine sulfoxide reductase B1 0.00508073
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00505914
SCAF4 SR-related CTD-associated factor 4 0.00503095
ISG15 ISG15 ubiquitin-like modifier 0.00503032
CRYAB crystallin, alpha B 0.00503024
SPEN spen family transcriptional repressor 0.00501148
PDLIM2 PDZ and LIM domain 2 (mystique) 0.00498659
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00496778
INSM1 insulinoma-associated 1 0.00496737
HEPH hephaestin 0.00494558
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.00493631
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.00491758
PFKM phosphofructokinase, muscle 0.00491629
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.00489783
MAEA macrophage erythroblast attacher 0.0048956
PON3 paraoxonase 3 0.00487444
TRAF1 TNF receptor-associated factor 1 0.00487093
ZMYM2 zinc finger, MYM-type 2 0.00486458
XAF1 XIAP associated factor 1 0.00486065
FXR1 fragile X mental retardation, autosomal homolog 1 0.00484679
MTA1 metastasis associated 1 0.00484614
AQP3 aquaporin 3 (Gill blood group) 0.0048321
MAB21L2 mab-21-like 2 (C. elegans) 0.00481908
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.00481777
XIC X chromosome inactivation center 0.00479572
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00478049
SFN stratifin 0.00477643
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.0047548
ASPA aspartoacylase 0.00475395
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00475237
ARF1 ADP-ribosylation factor 1 0.00475085
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00473956
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00469763
NID1 nidogen 1 0.00469514
PCOLCE procollagen C-endopeptidase enhancer 0.00469079
DCN decorin 0.00468383
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00467416
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00467128
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.00466836
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00465951
STMN2 stathmin 2 0.00465563
FZD7 frizzled class receptor 7 0.00462234
KLC1 kinesin light chain 1 0.00462219
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00461183
COPS7A COP9 signalosome subunit 7A 0.00460724
BSG basigin (Ok blood group) 0.00460363
OXTR oxytocin receptor 0.00460334
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.00459669
CAPNS1 calpain, small subunit 1 0.00459023
SGCE sarcoglycan, epsilon 0.00455581
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00455423
TBC1D4 TBC1 domain family, member 4 0.00455238
GAS6 growth arrest-specific 6 0.00455063
SCGB2A1 secretoglobin, family 2A, member 1 0.00452009
LRRC2 leucine rich repeat containing 2 0.00451274
TCTA T-cell leukemia translocation altered 0.00450497
DTX4 deltex 4, E3 ubiquitin ligase 0.00448539
NCOR2 nuclear receptor corepressor 2 0.00448321
SNAI2 snail family zinc finger 2 0.00448209
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00447807
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00447496
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.00446974
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00446368
HLX H2.0-like homeobox 0.00445848
ZMYND8 zinc finger, MYND-type containing 8 0.00445718
DST dystonin 0.00445529
ZBED2 zinc finger, BED-type containing 2 0.00444864
METTL17 methyltransferase like 17 0.00444424
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.00444011
JMJD6 jumonji domain containing 6 0.00443732
LDB3 LIM domain binding 3 0.00443577
RYR1 ryanodine receptor 1 (skeletal) 0.00443237
PGAM1 phosphoglycerate mutase 1 (brain) 0.00442263
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.00442189
SAMD4A sterile alpha motif domain containing 4A 0.00441558
MEG3 maternally expressed 3 (non-protein coding) 0.00441412
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.0044068
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00440376
PLAGL1 pleiomorphic adenoma gene-like 1 0.00440249
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00439723
LAT2 linker for activation of T cells family, member 2 0.00439013
CLEC11A C-type lectin domain family 11, member A 0.00437648
PITX2 paired-like homeodomain 2 0.00436533
GYS1 glycogen synthase 1 (muscle) 0.00435964
IVNS1ABP influenza virus NS1A binding protein 0.00433878
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00433863
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.00433833
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00433557
ETHE1 ethylmalonic encephalopathy 1 0.00433536
MBNL2 muscleblind-like splicing regulator 2 0.00433242
CASQ2 calsequestrin 2 (cardiac muscle) 0.00432507

decreased expression

Symbol Name Standardized Value
MMP7 matrix metallopeptidase 7 -0.0130952
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0117448
LCN2 lipocalin 2 -0.0114112
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0108389
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.0102573
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0100407
TRPS1 trichorhinophalangeal syndrome I -0.00981651
TFF1 trefoil factor 1 -0.00969266
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00950195
ESR1 estrogen receptor 1 -0.00949835
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00946106
TXNDC9 thioredoxin domain containing 9 -0.00939607
EIF5A eukaryotic translation initiation factor 5A -0.00908862
LYZ lysozyme -0.00907987
PCP4 Purkinje cell protein 4 -0.00900225
OLFM4 olfactomedin 4 -0.00890199
MT1M metallothionein 1M -0.00889075
HAT1 histone acetyltransferase 1 -0.00883574
RTN1 reticulon 1 -0.00876308
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.008715
NANS N-acetylneuraminic acid synthase -0.00858889
NMU neuromedin U -0.00858629
FAM171A1 family with sequence similarity 171, member A1 -0.0083557
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00813645
PLBD1 phospholipase B domain containing 1 -0.0081158
CFB complement factor B -0.00803404
CPE carboxypeptidase E -0.00791042
GLUL glutamate-ammonia ligase -0.00789631
ZHX2 zinc fingers and homeoboxes 2 -0.00779713
TMSB15A thymosin beta 15a -0.00777628
STK39 serine threonine kinase 39 -0.00772709
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00771529
ADIRF adipogenesis regulatory factor -0.00758064
AGR2 anterior gradient 2 -0.00741412
BIRC2 baculoviral IAP repeat containing 2 -0.0074014
EPCAM epithelial cell adhesion molecule -0.0073803
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00734725
MT1F metallothionein 1F -0.00724264
VWF von Willebrand factor -0.00719375
ARG2 arginase 2 -0.007177
FGF13 fibroblast growth factor 13 -0.00716709
S100P S100 calcium binding protein P -0.00716422
MGP matrix Gla protein -0.00714173
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00710925
METTL7A methyltransferase like 7A -0.00707097
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00701818
SOX17 SRY (sex determining region Y)-box 17 -0.0069943
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00698313
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00686114
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00684486
CAB39 calcium binding protein 39 -0.00676258
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0067531
CDC42 cell division cycle 42 -0.00671815
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00669612
ALCAM activated leukocyte cell adhesion molecule -0.00668573
NIBAN1 niban apoptosis regulator 1 -0.00667446
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00667231
CRYM crystallin, mu -0.0066308
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00656673
EFNB2 ephrin-B2 -0.00653977
MECOM MDS1 and EVI1 complex locus -0.0065374
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00652776
TOR1A torsin family 1, member A (torsin A) -0.0065121
OSBPL10 oxysterol binding protein-like 10 -0.00650905
GOLM1 golgi membrane protein 1 -0.00650862
LPAR6 lysophosphatidic acid receptor 6 -0.00645832
ACP3 acid phosphatase 3 -0.00638539
ANPEP alanyl (membrane) aminopeptidase -0.00632037
SCARB2 scavenger receptor class B, member 2 -0.00630133
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00629145
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.006248
SORD sorbitol dehydrogenase -0.00623574
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.00621642
HIST1H2AC histone cluster 1, H2ac -0.00620678
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00619419
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00619214
TGFA transforming growth factor, alpha -0.00618699
SPARCL1 SPARC-like 1 (hevin) -0.00617575
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00609076
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00608375
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00607319
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00606256
NKX3-1 NK3 homeobox 1 -0.00604092
ZNF423 zinc finger protein 423 -0.00600389
HDAC4 histone deacetylase 4 -0.00599927
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00598804
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00597524
MSLN mesothelin -0.00597034
GLUD1 glutamate dehydrogenase 1 -0.00596442
TSPAN13 tetraspanin 13 -0.00594327
LIPT1 lipoyltransferase 1 -0.00594239
ADI1 acireductone dioxygenase 1 -0.00590914
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00590652
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00589098
HYOU1 hypoxia up-regulated 1 -0.00584524
CAVIN2 caveolae associated protein 2 -0.0058395
KIF14 kinesin family member 14 -0.00582017
MLPH melanophilin -0.00575557
S100A8 S100 calcium binding protein A8 -0.0057432
KRT18 keratin 18, type I -0.00573957
NEBL nebulette -0.00572162
CPA3 carboxypeptidase A3 (mast cell) -0.00570239
RGS10 regulator of G-protein signaling 10 -0.00565114
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00562075
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00561227
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.0055775
KRCC1 lysine-rich coiled-coil 1 -0.0055713
NCAM1 neural cell adhesion molecule 1 -0.00555313
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00552899
ANOS1 anosmin 1 -0.00552078
PKP4 plakophilin 4 -0.00550112
APOLD1 apolipoprotein L domain containing 1 -0.00546848
ANXA3 annexin A3 -0.00546702
GIMAP6 GTPase, IMAP family member 6 -0.00545382
TWSG1 twisted gastrulation BMP signaling modulator 1 -0.00545257
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00544565
YAP1 Yes-associated protein 1 -0.0054403
NRGN neurogranin (protein kinase C substrate, RC3) -0.00543815
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00542961
FZD5 frizzled class receptor 5 -0.00541916
CAND1 cullin-associated and neddylation-dissociated 1 -0.0053984
GPM6B glycoprotein M6B -0.00539797
COL9A2 collagen, type IX, alpha 2 -0.00539769
HIST1H2AE histone cluster 1, H2ae -0.00539757
CETN2 centrin, EF-hand protein, 2 -0.00539709
PRPF4 pre-mRNA processing factor 4 -0.00539017
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.0053635
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0053593
KLK2 kallikrein-related peptidase 2 -0.00535877
CD320 CD320 molecule -0.00535639
CHRDL1 chordin-like 1 -0.00534112
KLK3 kallikrein-related peptidase 3 -0.00533968
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00533632
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -0.00533206
REG3A regenerating islet-derived 3 alpha -0.00531771
GNS glucosamine (N-acetyl)-6-sulfatase -0.00526375
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00525992
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00524277
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00523231
CCL14 chemokine (C-C motif) ligand 14 -0.00521598
FZD6 frizzled class receptor 6 -0.00521443
WTAP Wilms tumor 1 associated protein -0.00520791
IFRD2 interferon-related developmental regulator 2 -0.00520191
ANO1 anoctamin 1, calcium activated chloride channel -0.00519416
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.0051802
PITX3 paired-like homeodomain 3 -0.00515747
MT1E metallothionein 1E -0.00514407
FGFR3 fibroblast growth factor receptor 3 -0.00513835
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.005138
NOTCH2 notch 2 -0.00513717
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.00513402
RNF130 ring finger protein 130 -0.0051254
PDGFC platelet derived growth factor C -0.00511855
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00511462
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00510112
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00508568
KAT6B K(lysine) acetyltransferase 6B -0.00508286
CD9 CD9 molecule -0.00506992
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.00506736
MRPL13 mitochondrial ribosomal protein L13 -0.00504176
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00503005
SNX10 sorting nexin 10 -0.00502807
SFRP4 secreted frizzled-related protein 4 -0.00501933
MT1G metallothionein 1G -0.00501343
RESF1 retroelement silencing factor 1 -0.00499129
NPM3 nucleophosmin/nucleoplasmin 3 -0.00499057
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00498611
TXNIP thioredoxin interacting protein -0.00496976
EPN2 epsin 2 -0.00496962
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00496399
ICAM2 intercellular adhesion molecule 2 -0.0049343
BMP7 bone morphogenetic protein 7 -0.00490545
HLA-DMB major histocompatibility complex, class II, DM beta -0.00490417
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -0.00490156
CLGN calmegin -0.00489707
BCR breakpoint cluster region -0.00489681
COX7B cytochrome c oxidase subunit VIIb -0.00489318
CEP70 centrosomal protein 70kDa -0.00489161
CD96 CD96 molecule -0.00489088
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00487356
VAV3 vav 3 guanine nucleotide exchange factor -0.00485109
C12ORF29 chromosome 12 open reading frame 29 -0.00484153
METTL18 methyltransferase like 18 -0.00483501
FAM107A family with sequence similarity 107, member A -0.00482411
DYNLT1 dynein, light chain, Tctex-type 1 -0.0048196
ASRGL1 asparaginase like 1 -0.00479725
SH3BP4 SH3-domain binding protein 4 -0.00478651
ESYT1 extended synaptotagmin-like protein 1 -0.00477722
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00477498
NTS neurotensin -0.00476968
TCEAL4 transcription elongation factor A (SII)-like 4 -0.00476947
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00476841
MDM1 Mdm1 nuclear protein homolog (mouse) -0.00475999
DNM3 dynamin 3 -0.00475365
GPR17 G protein-coupled receptor 17 -0.00474948
LXN latexin -0.00473497
ZFAND1 zinc finger, AN1-type domain 1 -0.00472289
CNN1 calponin 1, basic, smooth muscle -0.0047217
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00471266
FBP1 fructose-1,6-bisphosphatase 1 -0.00470729
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00470599
MT1X metallothionein 1X -0.0046868
ODC1 ornithine decarboxylase 1 -0.00467693
EGFL6 EGF-like-domain, multiple 6 -0.00467371
NDUFA4 NDUFA4, mitochondrial complex associated -0.00466961
EHF ets homologous factor -0.00466754
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.00466663
NDC80 NDC80 kinetochore complex component -0.00466572
GLIPR1 GLI pathogenesis-related 1 -0.00466191
ERLIN2 ER lipid raft associated 2 -0.00465792
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00465432
GTF2H5 general transcription factor IIH, polypeptide 5 -0.00465189
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00465012
BIRC3 baculoviral IAP repeat containing 3 -0.0046449
DERL2 derlin 2 -0.00464426
MAPK1 mitogen-activated protein kinase 1 -0.00462543
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -0.00460582
PNMA1 paraneoplastic Ma antigen 1 -0.00460445
CPD carboxypeptidase D -0.00460278
SOX9 SRY (sex determining region Y)-box 9 -0.00459342
FOXA1 forkhead box A1 -0.00459025
IL27RA interleukin 27 receptor, alpha -0.00458399
AQP9 aquaporin 9 -0.00457817
FAM162A family with sequence similarity 162, member A -0.00457548
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00457496
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -0.00457361
RTN3 reticulon 3 -0.00456806
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.00456125
PAGE4 P antigen family, member 4 (prostate associated) -0.00455819
OSBPL8 oxysterol binding protein-like 8 -0.00455547
TSPAN1 tetraspanin 1 -0.00455075
TSPYL5 TSPY-like 5 -0.00454548
TTC19 tetratricopeptide repeat domain 19 -0.00454111
COL1A2 collagen, type I, alpha 2 -0.00453101
WIPF1 WAS/WASL interacting protein family, member 1 -0.00451254
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00451236
CPB1 carboxypeptidase B1 (tissue) -0.00450695
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00449215
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00447822
ZSCAN16 zinc finger and SCAN domain containing 16 -0.00446997
MRS2 MRS2 magnesium transporter -0.00446531
TGIF2 TGFB-induced factor homeobox 2 -0.00446213
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00445154
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -0.00444956
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00444053
POGLUT2 protein O-glucosyltransferase 2 -0.00442866
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00442714
DSCC1 DNA replication and sister chromatid cohesion 1 -0.00442559
MSMB microseminoprotein, beta- -0.00442226
CTSB cathepsin B -0.00442179