DAPSONE Gene Set

Dataset	DGIdb Drug Targets 2026
Category	physical interactions
Type	drug
Description	A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. (Chemical Entities of Biological Interest Ontology, CHEBI_4325)
External Link	https://dgidb.org/results?searchType=drug&searchTerms=DAPSONE
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Genes

11 interacting proteins for the DAPSONE drug from theDGIdb Drug Targets 2026 dataset.

Symbol	Name	Standardized Value
TAS2R40	taste receptor, type 2, member 40	1.203
HLA-B	major histocompatibility complex, class I, B	0.687428
GNRH1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	0.534667
CYB5R3	cytochrome b5 reductase 3	0.343714
HLA-A	major histocompatibility complex, class I, A	0.260108
HLA-DRB1	major histocompatibility complex, class II, DR beta 1	0.139478
G6PD	glucose-6-phosphate dehydrogenase	0.048606
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.0220734
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.0164794
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.0157512
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.0108623