DBH Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description dopamine beta-hydroxylase (dopamine beta-monooxygenase)|The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1621)
External Link https://ncbi.nlm.nih.gov/gene/1621
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Genes

498 genes differentially expressed following the DBH gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
NPTX2 neuronal pentraxin II 0.0121774
AURKB aurora kinase B 0.0115641
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0110086
NXN nucleoredoxin 0.0109041
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.0099808
GTSE1 G-2 and S-phase expressed 1 0.00962259
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00954605
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00908839
ANPEP alanyl (membrane) aminopeptidase 0.00898302
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00864598
TBC1D16 TBC1 domain family, member 16 0.00860455
NVL nuclear VCP-like 0.00859801
MAGEA3 melanoma antigen family A3 0.0085909
RPA3 replication protein A3, 14kDa 0.0083951
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00830779
ARG2 arginase 2 0.00819284
DPYD dihydropyrimidine dehydrogenase 0.00814174
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00813709
EMX2 empty spiracles homeobox 2 0.0081322
FABP6 fatty acid binding protein 6, ileal 0.00811694
HOXC6 homeobox C6 0.00794984
RIPK4 receptor-interacting serine-threonine kinase 4 0.00778166
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00777513
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.0077522
DCXR dicarbonyl/L-xylulose reductase 0.0076227
HOXB2 homeobox B2 0.00760395
TACC3 transforming, acidic coiled-coil containing protein 3 0.0075998
CHMP6 charged multivesicular body protein 6 0.00759335
ALDOA aldolase A, fructose-bisphosphate 0.00758355
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00753164
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00752293
MUC16 mucin 16, cell surface associated 0.00751737
GNAS GNAS complex locus 0.00731422
CIRBP cold inducible RNA binding protein 0.00731154
FASN fatty acid synthase 0.00728889
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00727655
FZD2 frizzled class receptor 2 0.00725847
OIP5 Opa interacting protein 5 0.00722423
CREB1 cAMP responsive element binding protein 1 0.00714492
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00711101
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00711095
HMGB1 high mobility group box 1 0.00710423
KIF20A kinesin family member 20A 0.00704422
TGFB1 transforming growth factor, beta 1 0.00704249
TMSB15A thymosin beta 15a 0.00700305
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00698707
CRIP2 cysteine-rich protein 2 0.00696684
LDOC1 leucine zipper, down-regulated in cancer 1 0.00696672
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00694724
MDK midkine (neurite growth-promoting factor 2) 0.00693964
EHBP1L1 EH domain binding protein 1-like 1 0.00693656
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00691413
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.00690845
HOXC10 homeobox C10 0.00689648
NCAPD2 non-SMC condensin I complex, subunit D2 0.00687803
MRPL12 mitochondrial ribosomal protein L12 0.00687455
TRAPPC4 trafficking protein particle complex 4 0.00687006
MDFIC MyoD family inhibitor domain containing 0.00685409
TXLNA taxilin alpha 0.00683696
CXCL9 chemokine (C-X-C motif) ligand 9 0.00682386
FXYD2 FXYD domain containing ion transport regulator 2 0.0068201
TENT4A terminal nucleotidyltransferase 4A 0.00678456
ALB albumin 0.00676559
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.00675393
SOCS5 suppressor of cytokine signaling 5 0.00675097
TMPRSS4 transmembrane protease, serine 4 0.0067497
SST somatostatin 0.00667603
LYPD1 LY6/PLAUR domain containing 1 0.00667587
MMP2 matrix metallopeptidase 2 0.0066306
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00661685
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00659945
CERK ceramide kinase 0.00657395
EFHC2 EF-hand domain (C-terminal) containing 2 0.00656186
CCND1 cyclin D1 0.00653475
NSD2 nuclear receptor binding SET domain protein 2 0.00652662
FAM149A family with sequence similarity 149, member A 0.00652261
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00651418
ADAM9 ADAM metallopeptidase domain 9 0.00651254
FBXO5 F-box protein 5 0.00650982
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.0064742
CFH complement factor H 0.00646204
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00643492
SPC25 SPC25, NDC80 kinetochore complex component 0.00641532
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0063945
IPO9 importin 9 0.00637852
NREP neuronal regeneration related protein 0.00637138
SLC2A4RG SLC2A4 regulator 0.0063515
SSBP2 single-stranded DNA binding protein 2 0.00635063
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00631324
PSRC1 proline/serine-rich coiled-coil 1 0.00629425
HOXD1 homeobox D1 0.00629208
FAM114A1 family with sequence similarity 114, member A1 0.0062875
PER3 period circadian clock 3 0.00626619
PIMREG PICALM interacting mitotic regulator 0.00624088
TIMP3 TIMP metallopeptidase inhibitor 3 0.0062354
GCHFR GTP cyclohydrolase I feedback regulator 0.00623428
WFDC2 WAP four-disulfide core domain 2 0.00621946
TSPAN12 tetraspanin 12 0.00620135
CTNND1 catenin (cadherin-associated protein), delta 1 0.00618158
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00617283
HCRT hypocretin (orexin) neuropeptide precursor 0.00616622
HIP1 huntingtin interacting protein 1 0.00615401
STAT5B signal transducer and activator of transcription 5B 0.00615374
TRMT5 tRNA methyltransferase 5 0.00614196
AURKA aurora kinase A 0.00613406
CSK c-src tyrosine kinase 0.00609466
VARS valyl-tRNA synthetase 0.00608413
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00608394
FOLR1 folate receptor 1 (adult) 0.00606621
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00605756
UBL4A ubiquitin-like 4A 0.00603226
PLXNB2 plexin B2 0.00600667
NIPSNAP2 nipsnap homolog 2 0.00598949
HIC2 hypermethylated in cancer 2 0.00598593
MB myoglobin 0.00596894
METTL7A methyltransferase like 7A 0.00596262
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.00596175
FGFR3 fibroblast growth factor receptor 3 0.00593647
RAD51AP1 RAD51 associated protein 1 0.00589471
INTS1 integrator complex subunit 1 0.00588698
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.00588359
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.00587944
HMGN3 high mobility group nucleosomal binding domain 3 0.00585789
TMEM39B transmembrane protein 39B 0.00584854
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.00583445
CCNE2 cyclin E2 0.00583145
LBR lamin B receptor 0.00582923
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00582729
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00582679
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00582285
HAT1 histone acetyltransferase 1 0.00582031
ASRGL1 asparaginase like 1 0.00581621
PDGFC platelet derived growth factor C 0.00579726
COMP cartilage oligomeric matrix protein 0.00579177
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00578791
KCTD14 potassium channel tetramerization domain containing 14 0.00577554
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0057633
C20ORF27 chromosome 20 open reading frame 27 0.0057602
PEX2 peroxisomal biogenesis factor 2 0.00574983
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00574765
MPZL2 myelin protein zero-like 2 0.00572276
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00572264
KIF18B kinesin family member 18B 0.00572233
THAP7 THAP domain containing 7 0.0057222
L1CAM L1 cell adhesion molecule 0.00572099
TARDBP TAR DNA binding protein 0.00571116
ARMCX2 armadillo repeat containing, X-linked 2 0.00570035
ISYNA1 inositol-3-phosphate synthase 1 0.00569734
PKM pyruvate kinase, muscle 0.00567935
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0056792
ZDHHC4 zinc finger, DHHC-type containing 4 0.00567801
CIT citron rho-interacting serine/threonine kinase 0.0056775
ATF1 activating transcription factor 1 0.00566805
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.00566652
H2AZ1 H2A.Z variant histone 1 0.00565907
POSTN periostin, osteoblast specific factor 0.00564556
SCGB2A1 secretoglobin, family 2A, member 1 0.00563962
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00563845
AHR aryl hydrocarbon receptor 0.00563259
FOXM1 forkhead box M1 0.0056222
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.00562017
MCM5 minichromosome maintenance complex component 5 0.00561581
VEZF1 vascular endothelial zinc finger 1 0.0056122
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00560187
SLBP stem-loop binding protein 0.00559269
PDE8A phosphodiesterase 8A 0.00559213
NCAPD3 non-SMC condensin II complex, subunit D3 0.00559056
EXT1 exostosin glycosyltransferase 1 0.00558717
HAUS3 HAUS augmin-like complex, subunit 3 0.00558254
MUC4 mucin 4, cell surface associated 0.00556242
TRIP13 thyroid hormone receptor interactor 13 0.00556088
TSPAN4 tetraspanin 4 0.00554953
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.00554387
NPM3 nucleophosmin/nucleoplasmin 3 0.00553904
CCDC92 coiled-coil domain containing 92 0.00553844
PTPRC protein tyrosine phosphatase, receptor type, C 0.00552462
CP ceruloplasmin (ferroxidase) 0.0055051
DCK deoxycytidine kinase 0.00550283
DIDO1 death inducer-obliterator 1 0.00549141
MED28 mediator complex subunit 28 0.00548908
RYK receptor-like tyrosine kinase 0.00547155
NIT1 nitrilase 1 0.00546164
MEIS2 Meis homeobox 2 0.00545208
RNASEH2A ribonuclease H2, subunit A 0.00544732
NYNRIN NYN domain and retroviral integrase containing 0.00544344
NAXD NAD(P)HX dehydratase 0.00543506
THAP12 THAP domain containing 12 0.00543453
FST follistatin 0.00543441
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.0054342
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00541644
GCAT glycine C-acetyltransferase 0.00541377
PCLO piccolo presynaptic cytomatrix protein 0.00540959
FBXO3 F-box protein 3 0.00540421
FDPS farnesyl diphosphate synthase 0.00540376
EIF3B eukaryotic translation initiation factor 3, subunit B 0.00540197
HRASLS HRAS-like suppressor 0.00539371
KIF4A kinesin family member 4A 0.00539137
NUSAP1 nucleolar and spindle associated protein 1 0.00538681
DNAAF5 dynein, axonemal, assembly factor 5 0.00537949
MOK MOK protein kinase 0.00537407
BIRC5 baculoviral IAP repeat containing 5 0.00537354
DGCR8 DGCR8 microprocessor complex subunit 0.00537069
SEPTIN10 septin 10 0.00536583
VEGFB vascular endothelial growth factor B 0.00536536
IFRD2 interferon-related developmental regulator 2 0.00535991
CLGN calmegin 0.00535449
ILF2 interleukin enhancer binding factor 2 0.00535156
DDHD2 DDHD domain containing 2 0.00534721
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00532459
HMGN2 high mobility group nucleosomal binding domain 2 0.00532195
ZDHHC13 zinc finger, DHHC-type containing 13 0.00531226
PRPF8 pre-mRNA processing factor 8 0.00529435
ADSL adenylosuccinate lyase 0.00528575
GUK1 guanylate kinase 1 0.00528074
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00527836
NINJ2 ninjurin 2 0.00527722
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.00524226
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00524072
P3H2 prolyl 3-hydroxylase 2 0.00521056
IFT57 intraflagellar transport 57 0.00520544
USP1 ubiquitin specific peptidase 1 0.00520151
JCHAIN joining chain of multimeric IgA and IgM 0.00520085
SLC35E2B solute carrier family 35, member E2B 0.00519852
HAUS7 HAUS augmin-like complex, subunit 7 0.00519756
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00518461
FGL2 fibrinogen-like 2 0.00518419
GPS1 G protein pathway suppressor 1 0.00517634
EFHC1 EF-hand domain (C-terminal) containing 1 0.00516999
TMEM14B transmembrane protein 14B 0.00516382
LPAR6 lysophosphatidic acid receptor 6 0.00515992
ORC1 origin recognition complex, subunit 1 0.00515901
NDC80 NDC80 kinetochore complex component 0.0051538
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.00514949
PRKD3 protein kinase D3 0.00514937
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00513785
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.00512661
GAS1 growth arrest-specific 1 0.00512262
MECOM MDS1 and EVI1 complex locus 0.00512232
CBS cystathionine-beta-synthase 0.00511439
TUBGCP3 tubulin, gamma complex associated protein 3 0.00511217
MARCHF1 membrane associated ring-CH-type finger 1 0.0051112
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00511053
GRK2 G protein-coupled receptor kinase 2 0.00510359
E2F8 E2F transcription factor 8 0.00510307
GPR161 G protein-coupled receptor 161 0.00509852
CPE carboxypeptidase E 0.00508887
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.00508712
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.00508273

decreased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 -0.0205802
HSPA1A heat shock 70kDa protein 1A -0.0182788
CXCL8 chemokine (C-X-C motif) ligand 8 -0.017088
S100P S100 calcium binding protein P -0.0168922
LTF lactotransferrin -0.0156354
IFI6 interferon, alpha-inducible protein 6 -0.0154012
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0144423
RNF167 ring finger protein 167 -0.0139956
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0133217
HOPX HOP homeobox -0.0132442
CHI3L2 chitinase 3-like 2 -0.0124018
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0123103
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0123016
GPM6B glycoprotein M6B -0.01224
S100A7 S100 calcium binding protein A7 -0.0122336
ISG15 ISG15 ubiquitin-like modifier -0.0120527
RHOB ras homolog family member B -0.0120005
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0118941
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0117593
ABLIM1 actin binding LIM protein 1 -0.0116206
TRIM22 tripartite motif containing 22 -0.0114953
CRYAB crystallin, alpha B -0.0114023
STC2 stanniocalcin 2 -0.0113812
ANXA1 annexin A1 -0.0111391
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0110091
MYBPC1 myosin binding protein C, slow type -0.0109845
IFI44L interferon-induced protein 44-like -0.010762
IRS2 insulin receptor substrate 2 -0.0105992
HSPB8 heat shock 22kDa protein 8 -0.0105645
ADM adrenomedullin -0.0105508
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0105091
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0103705
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.01036
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0103292
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0102395
KRT6A keratin 6A, type II -0.0101234
C1S complement component 1, s subcomponent -0.0101168
IL1RN interleukin 1 receptor antagonist -0.010022
CNTN1 contactin 1 -0.00986171
METRN meteorin, glial cell differentiation regulator -0.00980559
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00979394
LIPG lipase, endothelial -0.00973005
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0097239
IL32 interleukin 32 -0.00963695
KRT14 keratin 14, type I -0.00960062
MX1 MX dynamin-like GTPase 1 -0.00956959
MT1X metallothionein 1X -0.00953037
PITX3 paired-like homeodomain 3 -0.0095143
TUBB2A tubulin, beta 2A class IIa -0.00946134
NEBL nebulette -0.00941848
GJA1 gap junction protein, alpha 1, 43kDa -0.00940135
RBM34 RNA binding motif protein 34 -0.00936111
NRCAM neuronal cell adhesion molecule -0.00932075
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00927258
PI3 peptidase inhibitor 3, skin-derived -0.00925214
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00924554
RAD23B RAD23 homolog B (S. cerevisiae) -0.0091145
SMAD3 SMAD family member 3 -0.0090481
KRT6B keratin 6B, type II -0.00899501
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0089866
SOX9 SRY (sex determining region Y)-box 9 -0.00897331
AKAP12 A kinase (PRKA) anchor protein 12 -0.00894101
SP110 SP110 nuclear body protein -0.00886047
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00879229
TFF1 trefoil factor 1 -0.0087615
ISG20 interferon stimulated exonuclease gene 20kDa -0.00874452
VEGFA vascular endothelial growth factor A -0.0087274
ABAT 4-aminobutyrate aminotransferase -0.00871245
HBEGF heparin-binding EGF-like growth factor -0.00866878
MCL1 myeloid cell leukemia 1 -0.00865423
KLF4 Kruppel-like factor 4 (gut) -0.00862674
DST dystonin -0.00855358
TPD52L1 tumor protein D52-like 1 -0.00855201
DEFB4A defensin, beta 4A -0.00851987
SAMD4A sterile alpha motif domain containing 4A -0.00851323
CA2 carbonic anhydrase II -0.00848859
TFF3 trefoil factor 3 (intestinal) -0.00847578
SPRR2B small proline-rich protein 2B -0.00842956
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00840868
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00839741
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00835791
LMCD1 LIM and cysteine-rich domains 1 -0.00835109
NMB neuromedin B -0.00834699
ABHD4 abhydrolase domain containing 4 -0.0083063
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00829878
ATF3 activating transcription factor 3 -0.00829757
TACSTD2 tumor-associated calcium signal transducer 2 -0.00828234
TRIM16 tripartite motif containing 16 -0.00827426
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00826574
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00825151
CHPT1 choline phosphotransferase 1 -0.00823794
AQP1 aquaporin 1 (Colton blood group) -0.00820596
CHIC2 cysteine-rich hydrophobic domain 2 -0.00819742
IRF9 interferon regulatory factor 9 -0.00819139
KLF6 Kruppel-like factor 6 -0.00813717
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0081242
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0081076
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00806783
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00804634
NARS1 asparaginyl-tRNA synthetase 1 -0.00802737
PMP2 peripheral myelin protein 2 -0.0080181
MYO1C myosin IC -0.00799525
CSTA cystatin A (stefin A) -0.00797972
PTHLH parathyroid hormone-like hormone -0.00791299
DDIT3 DNA-damage-inducible transcript 3 -0.00788399
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00787248
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00780202
MT1H metallothionein 1H -0.00778514
GRN granulin -0.00778045
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00775867
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00773251
GBP1 guanylate binding protein 1, interferon-inducible -0.0076843
ANOS1 anosmin 1 -0.00765958
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00765601
KRT15 keratin 15, type I -0.00765498
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00765188
TXNL1 thioredoxin-like 1 -0.00764645
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00763416
CA12 carbonic anhydrase XII -0.00762125
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00761852
PHF11 PHD finger protein 11 -0.00758903
COBL cordon-bleu WH2 repeat protein -0.00758601
BAALC brain and acute leukemia, cytoplasmic -0.00757759
KDSR 3-ketodihydrosphingosine reductase -0.00753403
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.00751462
FGF1 fibroblast growth factor 1 (acidic) -0.0074618
FXYD3 FXYD domain containing ion transport regulator 3 -0.00744774
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00744771
CTSL cathepsin L -0.00741825
TBX3 T-box 3 -0.00739386
EGR1 early growth response 1 -0.00739166
MT1HL1 metallothionein 1H-like 1 -0.00736344
GEM GTP binding protein overexpressed in skeletal muscle -0.00735077
NAMPT nicotinamide phosphoribosyltransferase -0.00733849
CH25H cholesterol 25-hydroxylase -0.00733655
OPHN1 oligophrenin 1 -0.00729633
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00729397
TSC22D1 TSC22 domain family, member 1 -0.0072928
MAP7 microtubule-associated protein 7 -0.00728903
KLK10 kallikrein-related peptidase 10 -0.00727111
RGS2 regulator of G-protein signaling 2 -0.00726732
IL6 interleukin 6 -0.00721439
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00721066
WARS1 tryptophanyl-tRNA synthetase 1 -0.00719561
DTNA dystrobrevin, alpha -0.00718343
PLAUR plasminogen activator, urokinase receptor -0.00713011
RND1 Rho family GTPase 1 -0.00712926
S100A10 S100 calcium binding protein A10 -0.00712734
LAMP3 lysosomal-associated membrane protein 3 -0.00712361
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00712263
S100A9 S100 calcium binding protein A9 -0.00710709
DSG3 desmoglein 3 -0.0071058
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00708775
SCD5 stearoyl-CoA desaturase 5 -0.00707586
ZMAT3 zinc finger, matrin-type 3 -0.00707254
TMEM100 transmembrane protein 100 -0.00705219
DUSP5 dual specificity phosphatase 5 -0.00705204
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00704081
VLDLR very low density lipoprotein receptor -0.00702362
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00700418
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -0.00699907
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00699539
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00699269
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.00696364
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00695573
KRT17 keratin 17, type I -0.00693815
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00692874
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00691421
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.00689328
HSPA2 heat shock 70kDa protein 2 -0.00686575
SFRP4 secreted frizzled-related protein 4 -0.00685342
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00684859
LAMC2 laminin, gamma 2 -0.00684633
IER3 immediate early response 3 -0.00680869
EGR2 early growth response 2 -0.00677868
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00677401
CST3 cystatin C -0.00675762
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0067567
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00675377
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00674762
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00674112
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00668423
ZFP36 ZFP36 ring finger protein -0.00667474
SPRR1B small proline-rich protein 1B -0.00666325
ARMCX3 armadillo repeat containing, X-linked 3 -0.00666184
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.0066597
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0066585
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00665064
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00664257
TENT5A terminal nucleotidyltransferase 5A -0.00662772
KDM3A lysine (K)-specific demethylase 3A -0.00661404
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00660597
MT1E metallothionein 1E -0.00660513
ZFAND5 zinc finger, AN1-type domain 5 -0.0066022
BTG1 B-cell translocation gene 1, anti-proliferative -0.00660078
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00659962
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00659641
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00659037
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00655672
GLRX glutaredoxin (thioltransferase) -0.00655493
AMACR alpha-methylacyl-CoA racemase -0.00655103
ANK2 ankyrin 2, neuronal -0.00653851
CST7 cystatin F (leukocystatin) -0.00651159
OASL 2'-5'-oligoadenylate synthetase-like -0.00649852
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -0.00649067
HIST1H2AC histone cluster 1, H2ac -0.00646274
USP18 ubiquitin specific peptidase 18 -0.00643287
PSAP prosaposin -0.00640912
AQP3 aquaporin 3 (Gill blood group) -0.00640641
LAMA3 laminin, alpha 3 -0.00639812
MT1M metallothionein 1M -0.00639799
ELL2 elongation factor, RNA polymerase II, 2 -0.00638291
FAM102A family with sequence similarity 102, member A -0.00637666
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00636285
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00634242
ADAM12 ADAM metallopeptidase domain 12 -0.00634004
S100A14 S100 calcium binding protein A14 -0.00632051
TSPAN31 tetraspanin 31 -0.00631667
FHL2 four and a half LIM domains 2 -0.00630726
STOM stomatin -0.00630637
SH3YL1 SH3 and SYLF domain containing 1 -0.00629432
MT1G metallothionein 1G -0.00629256
UBE2H ubiquitin-conjugating enzyme E2H -0.00628828
AK4 adenylate kinase 4 -0.00626908
SCRG1 stimulator of chondrogenesis 1 -0.00625288
SHFL shiftless antiviral inhibitor of ribosomal frameshifting -0.00623098
S100A8 S100 calcium binding protein A8 -0.00622854
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00622515
TPP1 tripeptidyl peptidase I -0.00619861
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00619857
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00619564
OXTR oxytocin receptor -0.0061889
IER5 immediate early response 5 -0.00617569
XBP1 X-box binding protein 1 -0.00617457
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00617134
GBP2 guanylate binding protein 2, interferon-inducible -0.00616914
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00614592
KLK13 kallikrein-related peptidase 13 -0.00614414
SELE selectin E -0.00612798
FABP4 fatty acid binding protein 4, adipocyte -0.00611814
SAMD9 sterile alpha motif domain containing 9 -0.00610717
GATA6 GATA binding protein 6 -0.00610585
PNMA2 paraneoplastic Ma antigen 2 -0.00610288
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -0.00609656
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00609427
MT1F metallothionein 1F -0.00609027
MID1IP1 MID1 interacting protein 1 -0.00606728
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00605011
SOX4 SRY (sex determining region Y)-box 4 -0.00604228
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00601874