DBT Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description dihydrolipoamide branched chain transacylase E2|The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1629)
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Genes

422 genes differentially expressed following the DBT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NOTO notochord homeobox 2.73106
SLC16A6 solute carrier family 16, member 6 2.73106
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 2.73106
FAM156B family with sequence similarity 156, member B 2.73106
LIN37 lin-37 DREAM MuvB core complex component 2.73106
SIGLEC7 sialic acid binding Ig-like lectin 7 2.73106
RPP30 ribonuclease P/MRP 30kDa subunit 2.73106
ASB12 ankyrin repeat and SOCS box containing 12 2.73106
FNDC7 fibronectin type III domain containing 7 2.73106
TUBB1 tubulin, beta 1 class VI 2.73106
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.73106
FABP5 fatty acid binding protein 5 (psoriasis-associated) 2.73106
PBOV1 prostate and breast cancer overexpressed 1 2.73106
ARHGAP32 Rho GTPase activating protein 32 2.73106
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.73106
IFT172 intraflagellar transport 172 2.73106
USP26 ubiquitin specific peptidase 26 2.73106
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.73106
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.73106
CD19 CD19 molecule 2.73106
SPATA31A6 SPATA31 subfamily A, member 6 2.73106
SPINK4 serine peptidase inhibitor, Kazal type 4 2.73106
SLC16A11 solute carrier family 16, member 11 2.73106
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.73106
PRELP proline/arginine-rich end leucine-rich repeat protein 2.73106
BTC betacellulin 2.73106
MGAM2 maltase-glucoamylase 2 (putative) 2.73106
IQCJ IQ motif containing J 2.73106
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.73106
SLC23A3 solute carrier family 23, member 3 2.73106
SUSD2 sushi domain containing 2 2.73106
BMP4 bone morphogenetic protein 4 2.73106
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 2.73106
SCAI suppressor of cancer cell invasion 2.73106
MYL7 myosin, light chain 7, regulatory 2.73106
FAM181B family with sequence similarity 181, member B 2.73106
NWD2 NACHT and WD repeat domain containing 2 2.73106
KIAA1755 KIAA1755 2.73106
NPB neuropeptide B 2.73106
ACRBP acrosin binding protein 2.73106
MEIG1 meiosis/spermiogenesis associated 1 2.73106
GALP galanin-like peptide 2.73106
ABRA actin binding Rho activating protein 2.73106
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 2.73106
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2.73106
LRRC61 leucine rich repeat containing 61 2.73106
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.73106
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.73106
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.73106
BHLHE40 basic helix-loop-helix family, member e40 2.73106
PCDH8 protocadherin 8 2.73106
C1ORF141 chromosome 1 open reading frame 141 2.73106
TMEM217 transmembrane protein 217 2.73106
LCN12 lipocalin 12 2.73106
FAM229A family with sequence similarity 229, member A 2.73106
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 2.73106
IDUA iduronidase, alpha-L- 2.73106
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 2.73106
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.73106
MYO7B myosin VIIB 2.73106
SPMIP11 sperm microtubule inner protein 11 2.73106
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.73106
AHNAK2 AHNAK nucleoprotein 2 2.73106
RD3 retinal degeneration 3 2.73106
KRT86 keratin 86, type II 2.73106
ADRB3 adrenoceptor beta 3 2.73106
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.73106
DOK7 docking protein 7 2.73106
BCO2 beta-carotene oxygenase 2 2.73106
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.73106
LRRN4CL LRRN4 C-terminal like 2.73106
LTF lactotransferrin 2.73106
PRG4 proteoglycan 4 2.73106
PNLIPRP1 pancreatic lipase-related protein 1 2.73106
PNLIPRP2 pancreatic lipase-related protein 2 2.73106
ALX4 ALX homeobox 4 2.73106
CIMIP2C ciliary microtubule inner protein 2C 2.73106
TNS1-AS1 TNS1 antisense RNA 1 2.73106
SPMIP8 sperm microtubule inner protein 8 2.73106
CCDC194 coiled-coil domain containing 194 2.73106
IQCN IQ motif containing N 2.73106
ITPRID1 ITPR interacting domain containing 1 2.73106
DIPK1C divergent protein kinase domain 1C 2.73106
VXN vexin 2.73106
SLC49A3 solute carrier family 49 member 3 2.73106
CCN3 cellular communication network factor 3 2.73106
ANGPTL8 angiopoietin like 8 2.73106
AVPR1A arginine vasopressin receptor 1A 2.73106
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 2.73106
VCX3B variable charge, X-linked 3B 2.73106
SPAG4 sperm associated antigen 4 2.73106
TMIE transmembrane inner ear 2.73106
RHOXF2 Rhox homeobox family, member 2 2.73106
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.73106
CAPN14 calpain 14 2.73106
ACTL8 actin-like 8 2.73106
IZUMO1 izumo sperm-egg fusion 1 2.73106
RAET1L retinoic acid early transcript 1L 2.73106
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.73106
OVGP1 oviductal glycoprotein 1, 120kDa 2.73106
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.73106
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.73106
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.73106
CLDN5 claudin 5 2.73106
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 2.73106
DSG1 desmoglein 1 2.73106
C7ORF57 chromosome 7 open reading frame 57 2.73106
UTS2 urotensin 2 2.73106
S100G S100 calcium binding protein G 2.73106
LECT2 leukocyte cell-derived chemotaxin 2 2.73106
MIA melanoma inhibitory activity 2.73106
TLR5 toll-like receptor 5 2.73106
NPIPB9 nuclear pore complex interacting protein family, member B9 2.73106
CXCL14 chemokine (C-X-C motif) ligand 14 2.73106
CD79A CD79a molecule, immunoglobulin-associated alpha 2.73106
OR2J1 olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene) 2.73106
MAL mal, T-cell differentiation protein 2.73106
DAO D-amino-acid oxidase 2.73106
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.73106
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.73106
GP2 glycoprotein 2 (zymogen granule membrane) 2.73106
ZNF541 zinc finger protein 541 2.73106
CXCR2 chemokine (C-X-C motif) receptor 2 2.73106
GCOM1 GRINL1A complex locus 1 2.73106
NOX3 NADPH oxidase 3 2.73106
FAIM2 Fas apoptotic inhibitory molecule 2 2.73106
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.73106
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.73106
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.73106
GOLGA6A golgin A6 family, member A 2.73106
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.73106
ERICH6 glutamate-rich 6 2.73106
OPTC opticin 2.73106
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.73106
PCDHGB1 protocadherin gamma subfamily B, 1 2.73106
CRHBP corticotropin releasing hormone binding protein 2.73106
CCDC152 coiled-coil domain containing 152 2.73106
PLA2G2C phospholipase A2, group IIC 2.73106
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.73106
KLHDC1 kelch domain containing 1 2.73106
FBP1 fructose-1,6-bisphosphatase 1 2.73106
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 2.73106
WFDC8 WAP four-disulfide core domain 8 2.73106
TMPPE transmembrane protein with metallophosphoesterase domain 2.73106
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.73106
TTC16 tetratricopeptide repeat domain 16 2.73106
C20ORF144 chromosome 20 open reading frame 144 2.73106
CDRT15L2 CMT1A duplicated region transcript 15-like 2 2.73106
DMRT1 doublesex and mab-3 related transcription factor 1 2.73106
TRAPPC4 trafficking protein particle complex 4 2.73106
RBM24 RNA binding motif protein 24 2.73106
GLB1L2 galactosidase, beta 1-like 2 2.73106
TF transferrin 2.73106
ZC3H11D zinc finger CCCH-type containing 11D 2.73106
COL17A1 collagen, type XVII, alpha 1 2.73106
IL11 interleukin 11 2.73106
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 2.73106
OAZ3 ornithine decarboxylase antizyme 3 2.73106
LYPD5 LY6/PLAUR domain containing 5 2.73106
PLCD4 phospholipase C, delta 4 2.73106
GPR62 G protein-coupled receptor 62 2.73106
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.73106
FIBIN fin bud initiation factor homolog (zebrafish) 2.73106
CCDC27 coiled-coil domain containing 27 2.73106
DRD2 dopamine receptor D2 2.73106
CRHR1 corticotropin releasing hormone receptor 1 2.73106
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.73106
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.73106
BTG4 B-cell translocation gene 4 2.73106
PADI3 peptidyl arginine deiminase, type III 2.73106
ADRA2A adrenoceptor alpha 2A 2.73106
LRRC38 leucine rich repeat containing 38 2.73106
PCDHAC1 protocadherin alpha subfamily C, 1 2.73106
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.73106
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.73106
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 2.73106
DRC1 dynein regulatory complex subunit 1 2.73106
SPDYE2B speedy/RINGO cell cycle regulator family member E2B 2.73106
SSX3 synovial sarcoma, X breakpoint 3 2.73106
NLRP14 NLR family, pyrin domain containing 14 2.73106
LOXL4 lysyl oxidase-like 4 2.73106
C5ORF46 chromosome 5 open reading frame 46 2.73106
DKK2 dickkopf WNT signaling pathway inhibitor 2 2.73106
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.73106
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 2.73106
CDCP2 CUB domain containing protein 2 2.73106
PLA2G1B phospholipase A2, group IB (pancreas) 2.73106
SHBG sex hormone-binding globulin 2.73106
VWC2L von Willebrand factor C domain containing protein 2-like 2.73106
OR11G2 olfactory receptor, family 11, subfamily G, member 2 2.73106
CXORF58 chromosome X open reading frame 58 2.73106
TBC1D28 TBC1 domain family, member 28 2.73106
AOC3 amine oxidase, copper containing 3 2.73106
GPRC6A G protein-coupled receptor, class C, group 6, member A 2.73106
NUTM2G NUT family member 2G 2.73106
LIMS2 LIM and senescent cell antigen-like domains 2 2.73106
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 2.73106
RORC RAR-related orphan receptor C 2.73106
CCDC159 coiled-coil domain containing 159 2.73106
MEPE matrix extracellular phosphoglycoprotein 2.73106
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.73106
ACAA2 acetyl-CoA acyltransferase 2 2.73106
DEK DEK proto-oncogene 2.73106
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.73106
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.73106
NPAS4 neuronal PAS domain protein 4 2.73106
CARNS1 carnosine synthase 1 2.73106
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.73106
DISP1 dispatched homolog 1 (Drosophila) 2.69565
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 2.65133
CYB561A3 cytochrome b561 family, member A3 2.6052
FBXO16 F-box protein 16 2.58921
FAM133B family with sequence similarity 133, member B 2.58902
H3C1 H3 clustered histone 1 2.57495
C11ORF52 chromosome 11 open reading frame 52 2.57495
ADORA2A adenosine A2a receptor 2.57495
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.53908
NECAB3 N-terminal EF-hand calcium binding protein 3 2.53705
SNRPB2 small nuclear ribonucleoprotein polypeptide B 2.53705
APOA1 apolipoprotein A-I 2.52906
ADK adenosine kinase 2.51279
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 2.49948
UNC5A unc-5 homolog A (C. elegans) 2.49326
H3-7 H3.7 histone (putative) 2.47934
ZBBX zinc finger, B-box domain containing 2.47934
FPGS folylpolyglutamate synthase 2.46003
PDE10A phosphodiesterase 10A 2.45091
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 2.45091
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 2.45026
RBM44 RNA binding motif protein 44 2.44215
TLN1 talin 1 2.43287
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 2.37447
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 2.37107
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.37107
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 2.36619
KIAA0319L KIAA0319-like 2.36523
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 2.33659
CNIH1 cornichon family AMPA receptor auxiliary protein 1 2.32921
ZNF593 zinc finger protein 593 2.32921
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 2.30392
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.29235
TLCD1 TLC domain containing 1 2.28146
RPL26 ribosomal protein L26 2.28146
CFAP298 cilia and flagella associated protein 298 2.22797
DIS3L DIS3 like exosome 3'-5' exoribonuclease 2.22797
TXNL1 thioredoxin-like 1 2.21711
ABHD4 abhydrolase domain containing 4 2.21224
CUX2 cut-like homeobox 2 2.1938
ASTN1 astrotactin 1 2.19142
HMOX1 heme oxygenase 1 2.15301
FAM169A family with sequence similarity 169, member A 2.14338
MRPL49 mitochondrial ribosomal protein L49 2.14338
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.11977
SAFB scaffold attachment factor B 2.11977
ECD ecdysoneless homolog (Drosophila) 2.11977
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.11977
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 2.11767
UNC5D unc-5 homolog D (C. elegans) 2.10885
RNASEH2B ribonuclease H2, subunit B 2.10885
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 2.10885
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.10885
BACE2 beta-site APP-cleaving enzyme 2 2.0988
CCDC15 coiled-coil domain containing 15 2.06897
CUL2 cullin 2 2.06504
TCP1 t-complex 1 2.06125
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.05524
RTN3 reticulon 3 2.0496
ORAI1 ORAI calcium release-activated calcium modulator 1 2.04536
CPT2 carnitine palmitoyltransferase 2 2.03812
NOS3 nitric oxide synthase 3 (endothelial cell) 2.03759
RIN3 Ras and Rab interactor 3 2.02984
SSBP1 single-stranded DNA binding protein 1, mitochondrial 2.02845
PINK1 PTEN induced putative kinase 1 2.02283
CALM2 calmodulin 2 (phosphorylase kinase, delta) 2.00238

decreased expression

Symbol Name Standardized Value
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -2.73106
LEFTY1 left-right determination factor 1 -2.73106
MEI1 meiosis inhibitor 1 -2.73106
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -2.73106
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -2.73106
DYDC1 DPY30 domain containing 1 -2.73106
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.73106
VSTM2A V-set and transmembrane domain containing 2A -2.73106
LAMC1 laminin, gamma 1 (formerly LAMB2) -2.73106
CHADL chondroadherin-like -2.73106
RELL1 RELT-like 1 -2.73106
LHCGR luteinizing hormone/choriogonadotropin receptor -2.73106
LLGL1 lethal giant larvae homolog 1 (Drosophila) -2.73106
LRRC66 leucine rich repeat containing 66 -2.73106
MME membrane metallo-endopeptidase -2.73106
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -2.73106
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.73106
ECM1 extracellular matrix protein 1 -2.73106
C22ORF23 chromosome 22 open reading frame 23 -2.73106
DBT dihydrolipoamide branched chain transacylase E2 -2.73106
LIG4 ligase IV, DNA, ATP-dependent -2.73106
LMF2 lipase maturation factor 2 -2.73106
PRDM11 PR domain containing 11 -2.73106
MFAP3L microfibrillar-associated protein 3-like -2.73106
PCDHGB6 protocadherin gamma subfamily B, 6 -2.73106
SBK2 SH3 domain binding kinase family, member 2 -2.73106
EEF2 eukaryotic translation elongation factor 2 -2.73106
ACSBG2 acyl-CoA synthetase bubblegum family member 2 -2.73106
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.73106
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.73106
AOAH acyloxyacyl hydrolase (neutrophil) -2.73106
SPARCL1 SPARC-like 1 (hevin) -2.73106
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -2.73106
FMO3 flavin containing monooxygenase 3 -2.73106
DUSP9 dual specificity phosphatase 9 -2.73106
ZNF528 zinc finger protein 528 -2.73106
SGO1 shugoshin 1 -2.73106
PNMA8B PNMA family member 8B -2.73106
ANKRD53 ankyrin repeat domain 53 -2.73106
INSYN1 inhibitory synaptic factor 1 -2.73106
C19ORF85 chromosome 19 open reading frame 85 -2.73106
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 -2.73106
PCDHB10 protocadherin beta 10 -2.73106
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.73106
MROH7 maestro heat-like repeat family member 7 -2.73106
PCDH10 protocadherin 10 -2.73106
TTLL4 tubulin tyrosine ligase-like family member 4 -2.73106
LRP2BP LRP2 binding protein -2.73106
C1ORF167 chromosome 1 open reading frame 167 -2.73106
OAT ornithine aminotransferase -2.73106
AMH anti-Mullerian hormone -2.73106
TENM1 teneurin transmembrane protein 1 -2.71931
C20ORF96 chromosome 20 open reading frame 96 -2.68559
TRIM38 tripartite motif containing 38 -2.65133
ADGRG2 adhesion G protein-coupled receptor G2 -2.61028
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.60759
CCDC69 coiled-coil domain containing 69 -2.56426
TMEM35A transmembrane protein 35A -2.5534
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -2.54224
VEGFA vascular endothelial growth factor A -2.5411
ATG4C autophagy related 4C, cysteine peptidase -2.52765
REPS1 RALBP1 associated Eps domain containing 1 -2.52095
AP3B2 adaptor-related protein complex 3, beta 2 subunit -2.52095
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.48094
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.47511
PCLO piccolo presynaptic cytomatrix protein -2.47339
ZNF57 zinc finger protein 57 -2.47061
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -2.47061
SRSF4 serine/arginine-rich splicing factor 4 -2.47047
TMEM51 transmembrane protein 51 -2.45091
FZD4 frizzled class receptor 4 -2.41692
CPNE3 copine III -2.41614
ATG12 autophagy related 12 -2.41232
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -2.41232
HDAC6 histone deacetylase 6 -2.3888
PAMR1 peptidase domain containing associated with muscle regeneration 1 -2.37875
TRIP13 thyroid hormone receptor interactor 13 -2.37107
NIPSNAP2 nipsnap homolog 2 -2.34039
KIF5C kinesin family member 5C -2.33546
GAR1 GAR1 ribonucleoprotein -2.3295
ANTXR2 anthrax toxin receptor 2 -2.3295
RHOQ ras homolog family member Q -2.3295
CCDC172 coiled-coil domain containing 172 -2.32243
VWA5B1 von Willebrand factor A domain containing 5B1 -2.32243
GOLGA6L9 golgin A6 family-like 9 -2.30604
CSMD1 CUB and Sushi multiple domains 1 -2.28146
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules -2.28146
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -2.27272
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -2.27272
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 -2.26441
PROSER1 proline and serine rich 1 -2.23355
CCNB1 cyclin B1 -2.23131
TMCC2 transmembrane and coiled-coil domain family 2 -2.22797
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -2.22797
AFTPH aftiphilin -2.2235
SLC37A3 solute carrier family 37, member 3 -2.21623
HPS4 Hermansky-Pudlak syndrome 4 -2.21426
SH2D3A SH2 domain containing 3A -2.20715
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.20179
ZFHX2 zinc finger homeobox 2 -2.17658
ZNF222 zinc finger protein 222 -2.17025
PLK4 polo-like kinase 4 -2.17025
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -2.16346
YOD1 YOD1 deubiquitinase -2.16346
TTLL11 tubulin tyrosine ligase-like family member 11 -2.16346
KANTR KDM5C adjacent non-coding transcript -2.15423
SLX9 SLX9 ribosome biogenesis factor -2.15301
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.15301
YLPM1 YLP motif containing 1 -2.15301
LDLR low density lipoprotein receptor -2.15301
PDZD2 PDZ domain containing 2 -2.15301
UBQLN2 ubiquilin 2 -2.15301
HGH1 HGH1 homolog (S. cerevisiae) -2.14456
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.14338
CCDC40 coiled-coil domain containing 40 -2.14303
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -2.14303
CMTR2 cap methyltransferase 2 -2.1378
METTL25B methyltransferase like 25B -2.1378
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -2.13018
ZNF8 zinc finger protein 8 -2.12195
SYCP2L synaptonemal complex protein 2-like -2.11977
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 -2.11977
OGG1 8-oxoguanine DNA glycosylase -2.10885
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -2.10885
SPAG5 sperm associated antigen 5 -2.10648
TAFA1 TAFA chemokine like family member 1 -2.10648
TRIM68 tripartite motif containing 68 -2.10648
SPPL3 signal peptide peptidase like 3 -2.0988
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 -2.09414
NUP188 nucleoporin 188kDa -2.09289
RNASET2 ribonuclease T2 -2.08817
ABHD14A abhydrolase domain containing 14A -2.08481
PDS5A PDS5 cohesin associated factor A -2.08469
TENM2 teneurin transmembrane protein 2 -2.07485
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -2.07452
FBXW10B F-box and WD repeat domain containing 10B -2.07452
SPRED2 sprouty-related, EVH1 domain containing 2 -2.07452
LYRM7 LYR motif containing 7 -2.06891
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.0541
FBXO8 F-box protein 8 -2.0496
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.0496
SAP130 Sin3A-associated protein, 130kDa -2.04538
AMBRA1 autophagy/beclin-1 regulator 1 -2.04538
ZNF83 zinc finger protein 83 -2.04146
CRTAC1 cartilage acidic protein 1 -2.04064
ZNF671 zinc finger protein 671 -2.04064
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) -2.04064
BCL2L2 BCL2-like 2 -2.02647