DC-17-EL33_0.01uM Gene Set

Dataset	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category	transcriptomics
Type	drug perturbation
Description	Dose=0.01uM, 10-Methoxy-2,2,4-trimethyl-5-prop-2-enyl-1,5-dihydrochromeno[3,4-f]quinoline, Glucocorticoid Receptor (GR) Modulators targeting NR3C1 (Novartis, 9906282)
External Link	https://pubchem.ncbi.nlm.nih.gov/compound/9906282
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Genes

5 genes differentially expressed following the DC-17-EL33_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol	Name	Standardized Value
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.370173
PPDPF	pancreatic progenitor cell differentiation and proliferation factor	0.343506
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	0.205065

decreased expression

Symbol	Name	Standardized Value
CARD16	caspase recruitment domain family, member 16	-0.317144
VTI1A	vesicle transport through interaction with t-SNAREs 1A	-0.246371