DC-99-NQ50_10uM Gene Set
Genes
36 genes differentially expressed following the DC-99-NQ50_10uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
FAU
|
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
|
0.608229
|
|
LGALS1
|
lectin, galactoside-binding, soluble, 1
|
0.36747
|
|
RPS3
|
ribosomal protein S3
|
0.36747
|
|
DDTL
|
D-dopachrome tautomerase-like
|
0.361503
|
|
RPS7
|
ribosomal protein S7
|
0.35708
|
|
RPL38
|
ribosomal protein L38
|
0.325069
|
|
RPS5
|
ribosomal protein S5
|
0.304001
|
|
RPL13A
|
ribosomal protein L13a
|
0.292926
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
0.292926
|
|
ATP5PO
|
ATP synthase peripheral stalk subunit OSCP
|
0.28109
|
|
RPS18
|
ribosomal protein S18
|
0.275853
|
|
ELOB
|
elongin B
|
0.275606
|
|
RPL18
|
ribosomal protein L18
|
0.274991
|
|
RPL27
|
ribosomal protein L27
|
0.262056
|
|
RPL34
|
ribosomal protein L34
|
0.262056
|
|
IFI35
|
interferon-induced protein 35
|
0.262056
|
|
RPS21
|
ribosomal protein S21
|
0.261029
|
|
RPS12
|
ribosomal protein S12
|
0.254163
|
|
ATP5MF
|
ATP synthase membrane subunit f
|
0.252202
|
|
RPL36
|
ribosomal protein L36
|
0.230898
|
|
EEF1D
|
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
|
0.226882
|
|
UPP1
|
uridine phosphorylase 1
|
0.226882
|
|
RPL37
|
ribosomal protein L37
|
0.212979
|
|
RPLP0
|
ribosomal protein, large, P0
|
0.206277
|
|
RPS14
|
ribosomal protein S14
|
0.201592
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TBC1D10A
|
TBC1 domain family, member 10A
|
-0.346303
|
|
NEDD4L
|
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
|
-0.292926
|
|
RALY
|
RALY heterogeneous nuclear ribonucleoprotein
|
-0.292926
|
|
CAVIN1
|
caveolae associated protein 1
|
-0.292926
|
|
ACTG1
|
actin gamma 1
|
-0.25802
|
|
PPP2R1A
|
protein phosphatase 2, regulatory subunit A, alpha
|
-0.254163
|
|
PKM
|
pyruvate kinase, muscle
|
-0.226882
|
|
POTEF
|
POTE ankyrin domain family, member F
|
-0.201592
|
|
PTGES3
|
prostaglandin E synthase 3 (cytosolic)
|
-0.201592
|
|
SPHK1
|
sphingosine kinase 1
|
-0.201592
|
|
RSAD1
|
radical S-adenosyl methionine domain containing 1
|
-0.200268
|