DC-99-NQ50_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM, 4-methyl-2-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide, SCD inhibitor targeting SCD (Novartis, 25095148)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/25095148
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Genes

5 genes differentially expressed following the DC-99-NQ50_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
RPS29 ribosomal protein S29 0.299601
RPL35 ribosomal protein L35 0.22963
DDTL D-dopachrome tautomerase-like 0.22963

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.227982
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.225145