| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/DCA_UP.V1_UP |
| Similar Terms | |
| Downloads & Tools |
376 genes differentially expressed following the DCA_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ACP5 | acid phosphatase 5, tartrate resistant |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) |
| AHSP | alpha hemoglobin stabilizing protein |
| AIF1 | allograft inflammatory factor 1 |
| AK4P3 | adenylate kinase 4 pseudogene 3 |
| AK5 | adenylate kinase 5 |
| ALG1L2 | ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| ANKRD53 | ankyrin repeat domain 53 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ATF6 | activating transcription factor 6 |
| ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
| AURKB | aurora kinase B |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BEST1 | bestrophin 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMX | BMX non-receptor tyrosine kinase |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C22ORF31 | chromosome 22 open reading frame 31 |
| CA6 | carbonic anhydrase VI |
| CABIN1 | calcineurin binding protein 1 |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 |
| CAPN11 | calpain 11 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CATSPERB | catsper channel auxiliary subunit beta |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC87 | coiled-coil domain containing 87 |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CD1B | CD1b molecule |
| CD27 | CD27 molecule |
| CD70 | CD70 molecule |
| CD82 | CD82 molecule |
| CDC45 | cell division cycle 45 |
| CETN1 | centrin, EF-hand protein, 1 |
| CFAP70 | cilia and flagella associated protein 70 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLEC7A | C-type lectin domain family 7, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COBL | cordon-bleu WH2 repeat protein |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| COPG2 | coatomer protein complex, subunit gamma 2 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORT | cortistatin |
| CREB5 | cAMP responsive element binding protein 5 |
| CRIP2 | cysteine-rich protein 2 |
| CRYGB | crystallin, gamma B |
| CST2 | cystatin SA |
| CTSG | cathepsin G |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DCXR | dicarbonyl/L-xylulose reductase |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPP6 | dipeptidyl-peptidase 6 |
| EFS | embryonal Fyn-associated substrate |
| EIF3FP2 | eukaryotic translation initiation factor 3, subunit F pseudogene 2 |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| EPHB6 | EPH receptor B6 |
| EXO5 | exonuclease 5 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| F2 | coagulation factor II (thrombin) |
| FAM215A | family with sequence similarity 215, member A (non-protein coding) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF22 | fibroblast growth factor 22 |
| FGF6 | fibroblast growth factor 6 |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GIPR | gastric inhibitory polypeptide receptor |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPA33 | glycoprotein A33 (transmembrane) |
| GPR45 | G protein-coupled receptor 45 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
| GRM5 | glutamate receptor, metabotropic 5 |
| HCG9 | HLA complex group 9 (non-protein coding) |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H2BI | histone cluster 1, H2bi |
| HOXC5 | homeobox C5 |
| HTN1 | histatin 1 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNA10 | interferon, alpha 10 |
| IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) |
| IGLV2-14 | immunoglobulin lambda variable 2-14 |
| IL23A | interleukin 23, alpha subunit p19 |
| IL2RA | interleukin 2 receptor, alpha |
| IL36RN | interleukin 36 receptor antagonist |
| INO80B | INO80 complex subunit B |
| INSL3 | insulin-like 3 (Leydig cell) |
| IRGC | immunity-related GTPase family, cinema |
| IRX4 | iroquois homeobox 4 |
| ITGA8 | integrin, alpha 8 |
| KIAA0513 | KIAA0513 |
| KIAA1107 | KIAA1107 |
| KIF17 | kinesin family member 17 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL3 | kelch-like family member 3 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT13 | keratin 13, type I |
| LAMC3 | laminin, gamma 3 |
| LGALS7 | lectin, galactoside-binding, soluble, 7 |
| LIMD1 | LIM domains containing 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC79999 | uncharacterized LOC79999 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MIR600HG | MIR600 host gene |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MX1 | MX dynamin-like GTPase 1 |
| MYCT1 | myc target 1 |
| MYOZ3 | myozenin 3 |
| NPC1L1 | NPC1-like 1 |
| NRXN2 | neurexin 2 |
| NTN3 | netrin 3 |
| OR3A2 | olfactory receptor, family 3, subfamily A, member 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PLA2G2F | phospholipase A2, group IIF |
| PLAA | phospholipase A2-activating protein |
| PNMT | phenylethanolamine N-methyltransferase |
| PQLC3 | PQ loop repeat containing 3 |
| PRDM14 | PR domain containing 14 |
| PRO2964 | uncharacterized protein PRO2964 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTGFR | prostaglandin F receptor (FP) |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| RAI1 | retinoic acid induced 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPE65 | retinal pigment epithelium-specific protein 65kDa |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RRP7BP | ribosomal RNA processing 7 homolog B (S. cerevisiae), pseudogene |
| SARDH | sarcosine dehydrogenase |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA4 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SHCBP1L | SHC SH2-domain binding protein 1-like |
| SIX1 | SIX homeobox 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SNX17 | sorting nexin 17 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPIN2A | spindlin family, member 2A |
| TACR3 | tachykinin receptor 3 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEX13B | testis expressed 13B |
| TNNT2 | troponin T type 2 (cardiac) |
| TNS4 | tensin 4 |
| TSKS | testis-specific serine kinase substrate |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TYRO3 | TYRO3 protein tyrosine kinase |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP29 | ubiquitin specific peptidase 29 |
| USP6NL | USP6 N-terminal like |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WASL | Wiskott-Aldrich syndrome-like |
| WDR25 | WD repeat domain 25 |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZNF117 | zinc finger protein 117 |
| ZNF157 | zinc finger protein 157 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF639 | zinc finger protein 639 |
| ZNF750 | zinc finger protein 750 |
| ZNF91 | zinc finger protein 91 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADM2 | adrenomedullin 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ANAPC10 | anaphase promoting complex subunit 10 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ANKRD46 | ankyrin repeat domain 46 |
| ARHGAP15 | Rho GTPase activating protein 15 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATP10D | ATPase, class V, type 10D |
| AUNIP | aurora kinase A and ninein interacting protein |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C2CD2L | C2CD2-like |
| CA5A | carbonic anhydrase VA, mitochondrial |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CDH16 | cadherin 16, KSP-cadherin |
| CDK10 | cyclin-dependent kinase 10 |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CDON | cell adhesion associated, oncogene regulated |
| CHEK2 | checkpoint kinase 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLIC5 | chloride intracellular channel 5 |
| CMC1 | C-x(9)-C motif containing 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNTLN | centlein, centrosomal protein |
| COL21A1 | collagen, type XXI, alpha 1 |
| CPB2 | carboxypeptidase B2 (plasma) |
| CST7 | cystatin F (leukocystatin) |
| CTAG2 | cancer/testis antigen 2 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| ENO3 | enolase 3 (beta, muscle) |
| ETNPPL | ethanolamine-phosphate phospho-lyase |
| FAM204A | family with sequence similarity 204, member A |
| FAM222B | family with sequence similarity 222, member B |
| FGF9 | fibroblast growth factor 9 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GALR3 | galanin receptor 3 |
| GMPR | guanosine monophosphate reductase |
| GPR137B | G protein-coupled receptor 137B |
| GPR19 | G protein-coupled receptor 19 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GRAMD4 | GRAM domain containing 4 |
| GRID2 | glutamate receptor, ionotropic, delta 2 |
| GSDMD | gasdermin D |
| HIST1H3D | histone cluster 1, H3d |
| IFNA5 | interferon, alpha 5 |
| IFNG | interferon, gamma |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL10RA | interleukin 10 receptor, alpha |
| INSL5 | insulin-like 5 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JOSD1 | Josephin domain containing 1 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA0894 | KIAA0894 protein |
| KLHL1 | kelch-like family member 1 |
| KRT1 | keratin 1, type II |
| KRT24 | keratin 24, type I |
| KRT5 | keratin 5, type II |
| LAMA3 | laminin, alpha 3 |
| LAT | linker for activation of T cells |
| LIN7B | lin-7 homolog B (C. elegans) |
| LONP2 | lon peptidase 2, peroxisomal |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC14 | leucine rich repeat containing 14 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAGEB3 | melanoma antigen family B3 |
| MAGEH1 | melanoma antigen family H1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase |
| MATN4 | matrilin 4 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED23 | mediator complex subunit 23 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGC2889 | uncharacterized protein MGC2889 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MSH5 | mutS homolog 5 |
| MTRF1 | mitochondrial translational release factor 1 |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NACC1 | nucleus accumbens associated 1, BEN and BTB (POZ) domain containing |
| NFASC | neurofascin |
| NOL8 | nucleolar protein 8 |
| NOTCH2NL | notch 2 N-terminal like |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NUMB | numb homolog (Drosophila) |
| NUP62 | nucleoporin 62kDa |
| NXF2 | nuclear RNA export factor 2 |
| OR11A1 | olfactory receptor, family 11, subfamily A, member 1 |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PEX19 | peroxisomal biogenesis factor 19 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 |
| PKP1 | plakophilin 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLK3 | polo-like kinase 3 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PPCDC | phosphopantothenoylcysteine decarboxylase |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PRPF38B | pre-mRNA processing factor 38B |
| PRRX2 | paired related homeobox 2 |
| PTPRG | protein tyrosine phosphatase, receptor type, G |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RASL10A | RAS-like, family 10, member A |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBM14 | RNA binding motif protein 14 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RS1 | retinoschisin 1 |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| S100A14 | S100 calcium binding protein A14 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SETBP1 | SET binding protein 1 |
| SETD4 | SET domain containing 4 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SHOX2 | short stature homeobox 2 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SIRPB1 | signal-regulatory protein beta 1 |
| SKIL | SKI-like proto-oncogene |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC38A3 | solute carrier family 38, member 3 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNCB | synuclein, beta |
| SNX24 | sorting nexin 24 |
| SP140L | SP140 nuclear body protein-like |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPRR1A | small proline-rich protein 1A |
| STAG3 | stromal antigen 3 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STEAP1B | STEAP family member 1B |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBX6 | T-box 6 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TCL1B | T-cell leukemia/lymphoma 1B |
| TDRD7 | tudor domain containing 7 |
| TG | thyroglobulin |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM115 | transmembrane protein 115 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNRC18 | trinucleotide repeat containing 18 |
| TRIM52 | tripartite motif containing 52 |
| TRPM6 | transient receptor potential cation channel, subfamily M, member 6 |
| TXLNA | taxilin alpha |
| UPK1A | uroplakin 1A |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| YIPF3 | Yip1 domain family, member 3 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF248 | zinc finger protein 248 |
| ZNF286A | zinc finger protein 286A |
| ZNF32 | zinc finger protein 32 |
| ZNF652 | zinc finger protein 652 |
| ZNF821 | zinc finger protein 821 |
| ZNF84 | zinc finger protein 84 |
