DCC Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description DCC netrin 1 receptor|This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 1630)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DCC
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Genes

112 co-expressed genes for DCC from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM7 ADAM metallopeptidase domain 7
ADGRB3 adhesion G protein-coupled receptor B3
AKAP4 A kinase (PRKA) anchor protein 4
AKAP5 A kinase (PRKA) anchor protein 5
AKR1D1 aldo-keto reductase family 1, member D1
ANGPTL7 angiopoietin-like 7
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ART3 ADP-ribosyltransferase 3
ASTN1 astrotactin 1
ATG4B autophagy related 4B, cysteine peptidase
ATRNL1 attractin-like 1
AVPR1A arginine vasopressin receptor 1A
BAAT bile acid CoA:amino acid N-acyltransferase
BMPER BMP binding endothelial regulator
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRDT bromodomain, testis-specific
C18ORF25 chromosome 18 open reading frame 25
CASQ2 calsequestrin 2 (cardiac muscle)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COCH cochlin
CRISP1 cysteine-rich secretory protein 1
CRISP2 cysteine-rich secretory protein 2
CST5 cystatin D
CUL3 cullin 3
CXCL6 chemokine (C-X-C motif) ligand 6
DCAF4 DDB1 and CUL4 associated factor 4
DCC DCC netrin 1 receptor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DKFZP586K1520 DKFZP586K1520 protein
DMP1 dentin matrix acidic phosphoprotein 1
DOC2A double C2-like domains, alpha
DZIP1 DAZ interacting zinc finger protein 1
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EPHA7 EPH receptor A7
FAM134B family with sequence similarity 134, member B
FAM13C family with sequence similarity 13, member C
FOXN2 forkhead box N2
FRK fyn-related Src family tyrosine kinase
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIF gastric intrinsic factor (vitamin B synthesis)
GK2 glycerol kinase 2
GLDC glycine dehydrogenase (decarboxylating)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPR176 G protein-coupled receptor 176
GPR4 G protein-coupled receptor 4
GRM8 glutamate receptor, metabotropic 8
HCG4 HLA complex group 4 (non-protein coding)
HDAC9 histone deacetylase 9
HOXD9 homeobox D9
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFNA4 interferon, alpha 4
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT88 intraflagellar transport 88
IL9 interleukin 9
IPO8 importin 8
IREB2 iron-responsive element binding protein 2
IRGC immunity-related GTPase family, cinema
KALRN kalirin, RhoGEF kinase
KIAA0391 KIAA0391
KIAA1024 KIAA1024
KRT37 keratin 37, type I
LCAT lecithin-cholesterol acyltransferase
LCMT2 leucine carboxyl methyltransferase 2
LCT lactase
LRRTM2 leucine rich repeat transmembrane neuronal 2
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MPPED2 metallophosphoesterase domain containing 2
MTRF1L mitochondrial translational release factor 1-like
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYT1 myelin transcription factor 1
ODF2 outer dense fiber of sperm tails 2
OPHN1 oligophrenin 1
ORC4 origin recognition complex, subunit 4
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDCL phosducin-like
PPP6R2 protein phosphatase 6, regulatory subunit 2
PSMD4P1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 pseudogene 1
PTPRJ protein tyrosine phosphatase, receptor type, J
RBM17 RNA binding motif protein 17
RFPL1S RFPL1 antisense RNA 1
RFPL3S RFPL3 antisense
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RFXAP regulatory factor X-associated protein
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPGRIP1L RPGRIP1-like
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMG7-AS1 SMG7 antisense RNA 1
SPAG8 sperm associated antigen 8
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STARD13 StAR-related lipid transfer (START) domain containing 13
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TBC1D12 TBC1 domain family, member 12
TBC1D31 TBC1 domain family, member 31
TCF15 transcription factor 15 (basic helix-loop-helix)
TMEM257 transmembrane protein 257
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI2 troponin I type 2 (skeletal, fast)
TPH1 tryptophan hydroxylase 1
TRIM9 tripartite motif containing 9
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TTF1 transcription termination factor, RNA polymerase I
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
ZNF10 zinc finger protein 10
ZNF154 zinc finger protein 154
ZNF177 zinc finger protein 177
ZNF264 zinc finger protein 264