DCTN2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description dynactin 2 (p50)|This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012] (NCBI Entrez Gene Database, 10540)
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Genes

605 genes differentially expressed following the DCTN2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
C9ORF153 chromosome 9 open reading frame 153 3.999
MIA melanoma inhibitory activity 3.999
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 3.999
SPAG1 sperm associated antigen 1 3.999
UPP2 uridine phosphorylase 2 3.999
EPHB6 EPH receptor B6 3.999
ANKRD45 ankyrin repeat domain 45 3.999
BBS10 Bardet-Biedl syndrome 10 3.999
CNTN2 contactin 2 (axonal) 3.999
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 3.999
NLRX1 NLR family member X1 3.999
BTBD16 BTB (POZ) domain containing 16 3.999
MAP3K5 mitogen-activated protein kinase kinase kinase 5 3.999
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 3.999
ESR2 estrogen receptor 2 (ER beta) 3.999
GALE UDP-galactose-4-epimerase 3.999
DEF6 differentially expressed in FDCP 6 homolog (mouse) 3.999
BRPF1 bromodomain and PHD finger containing, 1 3.999
BMI1 BMI1 proto-oncogene, polycomb ring finger 3.999
RPH3AL rabphilin 3A-like (without C2 domains) 3.999
RPUSD1 RNA pseudouridylate synthase domain containing 1 3.999
TNS1 tensin 1 3.999
ARRDC4 arrestin domain containing 4 3.999
DZIP1L DAZ interacting zinc finger protein 1-like 3.999
RAB26 RAB26, member RAS oncogene family 3.999
RERG RAS-like, estrogen-regulated, growth inhibitor 3.999
TTLL7 tubulin tyrosine ligase-like family member 7 3.999
CCDC33 coiled-coil domain containing 33 3.999
FLT3LG fms-related tyrosine kinase 3 ligand 3.999
KIF25 kinesin family member 25 3.999
TMEM143 transmembrane protein 143 3.999
UBXN8 UBX domain protein 8 3.999
RUMY4 RUMY family member 4 3.999
SYVN1 synovial apoptosis inhibitor 1, synoviolin 3.999
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 3.999
MYO1H myosin IH 3.999
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 3.999
A2M alpha-2-macroglobulin 3.999
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae) 3.999
PPP1R37 protein phosphatase 1, regulatory subunit 37 3.999
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 3.999
ZNF829 zinc finger protein 829 3.999
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.999
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 3.999
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 3.999
ITPKB inositol-trisphosphate 3-kinase B 3.999
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 3.999
HHIPL1 HHIP-like 1 3.999
TRAPPC2B trafficking protein particle complex 2B 3.999
MT1M metallothionein 1M 3.999
PEX11B peroxisomal biogenesis factor 11 beta 3.999
PNMT phenylethanolamine N-methyltransferase 3.999
FITM2 fat storage-inducing transmembrane protein 2 3.999
PMP22 peripheral myelin protein 22 3.999
MCMDC2 minichromosome maintenance domain containing 2 3.999
ANXA3 annexin A3 3.999
FOXI3 forkhead box I3 3.999
PITX3 paired-like homeodomain 3 3.999
C16ORF54 chromosome 16 open reading frame 54 3.999
DCST1 DC-STAMP domain containing 1 3.999
APOA1 apolipoprotein A-I 3.999
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 3.999
CFAP43 cilia and flagella associated protein 43 3.999
C2CD2L C2CD2-like 3.999
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 3.999
TOM1 target of myb1 (chicken) 3.999
SIAE sialic acid acetylesterase 3.999
RASAL1 RAS protein activator like 1 (GAP1 like) 3.999
PIWIL2 piwi-like RNA-mediated gene silencing 2 3.999
AHSP alpha hemoglobin stabilizing protein 3.999
GPRC5C G protein-coupled receptor, class C, group 5, member C 3.999
TNS2 tensin 2 3.999
POU5F2 POU domain class 5, transcription factor 2 3.999
ADGRF3 adhesion G protein-coupled receptor F3 3.999
ZSCAN20 zinc finger and SCAN domain containing 20 3.999
ZNF597 zinc finger protein 597 3.999
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 3.999
NPR1 natriuretic peptide receptor 1 3.999
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 3.999
SLC26A7 solute carrier family 26 (anion exchanger), member 7 3.999
CD200R1L CD200 receptor 1-like 3.999
RHOXF2 Rhox homeobox family, member 2 3.999
C5ORF63 chromosome 5 open reading frame 63 3.999
CYB561D2 cytochrome b561 family, member D2 3.999
MITF microphthalmia-associated transcription factor 3.999
HES3 hes family bHLH transcription factor 3 3.999
C5ORF58 chromosome 5 open reading frame 58 3.999
CRAT carnitine O-acetyltransferase 3.999
MAP7D2 MAP7 domain containing 2 3.999
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 3.999
PNMA2 paraneoplastic Ma antigen 2 3.999
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.999
C1ORF53 chromosome 1 open reading frame 53 3.999
MAPRE3 microtubule-associated protein, RP/EB family, member 3 3.999
BHLHE41 basic helix-loop-helix family, member e41 3.999
HHEX hematopoietically expressed homeobox 3.999
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 3.999
FAM3B family with sequence similarity 3, member B 3.999
MEP1A meprin A, alpha (PABA peptide hydrolase) 3.999
C16ORF95 chromosome 16 open reading frame 95 3.999
RILP Rab interacting lysosomal protein 3.999
AKAP6 A kinase (PRKA) anchor protein 6 3.999
LCMT2 leucine carboxyl methyltransferase 2 3.999
MEI4 meiosis-specific 4 homolog (S. cerevisiae) 3.999
ZNF287 zinc finger protein 287 3.999
CD4 CD4 molecule 3.999
RNASE4 ribonuclease, RNase A family, 4 3.999
ZACN zinc activated ligand-gated ion channel 3.999
CSRP1 cysteine and glycine-rich protein 1 3.999
GDA guanine deaminase 3.999
BTN3A3 butyrophilin, subfamily 3, member A3 3.999
SNX22 sorting nexin 22 3.999
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 3.999
FBXO8 F-box protein 8 3.999
VAMP5 vesicle-associated membrane protein 5 3.999
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 3.999
D2HGDH D-2-hydroxyglutarate dehydrogenase 3.999
RNPC3 RNA-binding region (RNP1, RRM) containing 3 3.999
HIST1H2BF histone cluster 1, H2bf 3.999
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.999
IL17RB interleukin 17 receptor B 3.999
MKX mohawk homeobox 3.999
TRPV4 transient receptor potential cation channel, subfamily V, member 4 3.999
ZNF792 zinc finger protein 792 3.999
CA7 carbonic anhydrase VII 3.999
SARDH sarcosine dehydrogenase 3.999
PARM1 prostate androgen-regulated mucin-like protein 1 3.999
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.999
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 3.999
KDM6B lysine (K)-specific demethylase 6B 3.999
LBP lipopolysaccharide binding protein 3.999
PHKG1 phosphorylase kinase, gamma 1 (muscle) 3.999
SLC25A45 solute carrier family 25, member 45 3.999
CCDC62 coiled-coil domain containing 62 3.999
SNX21 sorting nexin family member 21 3.999
ITK IL2-inducible T-cell kinase 3.999
CCL2 chemokine (C-C motif) ligand 2 3.999
DCDC2 doublecortin domain containing 2 3.999
KBTBD6 kelch repeat and BTB (POZ) domain containing 6 3.999
LCAT lecithin-cholesterol acyltransferase 3.999
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 3.999
PRX periaxin 3.999
OLIG1 oligodendrocyte transcription factor 1 3.999
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.999
ZNF45 zinc finger protein 45 3.999
FBXO44 F-box protein 44 3.999
MAL mal, T-cell differentiation protein 3.999
GLYCTK glycerate kinase 3.999
SCRT1 scratch family zinc finger 1 3.999
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 3.999
CC2D1B coiled-coil and C2 domain containing 1B 3.999
MUC4 mucin 4, cell surface associated 3.999
ILDR1 immunoglobulin-like domain containing receptor 1 3.999
FANK1 fibronectin type III and ankyrin repeat domains 1 3.999
PSPN persephin 3.999
VSTM1 V-set and transmembrane domain containing 1 3.999
MAOA monoamine oxidase A 3.999
OCM oncomodulin 3.999
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 3.999
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 3.999
CAVIN3 caveolae associated protein 3 3.999
NIBAN3 niban apoptosis regulator 3 3.999
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 3.999
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 3.999
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 3.999
SIGLEC15 sialic acid binding Ig-like lectin 15 3.999
SEPTIN5 septin 5 3.999
RELN reelin 3.999
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 3.999
MRI1 methylthioribose-1-phosphate isomerase 1 3.999
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 3.999
RAG1 recombination activating gene 1 3.999
CDH12 cadherin 12, type 2 (N-cadherin 2) 3.999
NHLH2 nescient helix loop helix 2 3.999
PROSER3 proline and serine rich 3 3.999
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 3.999
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 3.999
SNX33 sorting nexin 33 3.999
PREB prolactin regulatory element binding 3.999
OSCAR osteoclast associated, immunoglobulin-like receptor 3.999
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.999
MUC12 mucin 12, cell surface associated 3.999
MUC19 mucin 19, oligomeric 3.999
CTC1 CTS telomere maintenance complex component 1 3.999
FOXRED2 FAD-dependent oxidoreductase domain containing 2 3.999
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 3.999
USP18 ubiquitin specific peptidase 18 3.999
MYO15A myosin XVA 3.999
TMEM31 transmembrane protein 31 3.999
ADGRL4 adhesion G protein-coupled receptor L4 3.999
ZNF417 zinc finger protein 417 3.999
C2ORF81 chromosome 2 open reading frame 81 3.999
PYY peptide YY 3.999
ZNG1F Zn regulated GTPase metalloprotein activator 1F 3.999
CNRIP1 cannabinoid receptor interacting protein 1 3.999
PLAC8L1 PLAC8-like 1 3.999
ALOX12B arachidonate 12-lipoxygenase, 12R type 3.999
CEND1 cell cycle exit and neuronal differentiation 1 3.999
H3C6 H3 clustered histone 6 3.999
LOC107985101 uncharacterized LOC107985101 3.999
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 3.999
FAM240C family with sequence similarity 240 member C 3.999
B3GAT1 beta-1,3-glucuronyltransferase 1 3.999
CFD complement factor D (adipsin) 3.999
UPK2 uroplakin 2 3.999
TSPAN16 tetraspanin 16 3.999
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 3.999
ZNF384 zinc finger protein 384 3.999
TMEM37 transmembrane protein 37 3.999
SCN1A sodium channel, voltage gated, type I alpha subunit 3.999
DOP1B DOP1 leucine zipper like protein B 3.999
TEPSIN TEPSIN adaptor related protein complex 4 accessory protein 3.999
SELENOP selenoprotein P 3.999
EEF1AKMT3 EEF1A lysine methyltransferase 3 3.999
PIERCE1 piercer of microtubule wall 1 3.999
CSDC2 cold shock domain containing C2, RNA binding 3.999
CDH20 cadherin 20, type 2 3.999
TAMALIN trafficking regulator and scaffold protein tamalin 3.999
THRB thyroid hormone receptor, beta 3.999
SPACA6 sperm acrosome associated 6 3.999
RAB27B RAB27B, member RAS oncogene family 3.999
RHEX regulator of hemoglobinization and erythroid cell expansion 3.999
LGALS14 lectin, galactoside-binding, soluble, 14 3.999
KCTD15 potassium channel tetramerization domain containing 15 3.999
UFSP1 UFM1-specific peptidase 1 (non-functional) 3.999
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 3.999
TULP2 tubby like protein 2 3.999
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 3.999
PKLR pyruvate kinase, liver and RBC 3.999
CPZ carboxypeptidase Z 3.999
CPM carboxypeptidase M 3.999
CCDC7 coiled-coil domain containing 7 3.999
ACBD4 acyl-CoA binding domain containing 4 3.999
C22ORF15 chromosome 22 open reading frame 15 3.999
VAX2 ventral anterior homeobox 2 3.999
SPTBN4 spectrin, beta, non-erythrocytic 4 3.999
TMEM102 transmembrane protein 102 3.999
CCL25 chemokine (C-C motif) ligand 25 3.999
TMEM132E transmembrane protein 132E 3.999
AVPI1 arginine vasopressin-induced 1 3.999
SOWAHC sosondowah ankyrin repeat domain family member C 3.999
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.999
TCEA3 transcription elongation factor A (SII), 3 3.999
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 3.999
GIPR gastric inhibitory polypeptide receptor 3.999
BST1 bone marrow stromal cell antigen 1 3.999
SH2D3C SH2 domain containing 3C 3.999
ENKUR enkurin, TRPC channel interacting protein 3.999
ACSL1 acyl-CoA synthetase long-chain family member 1 3.999
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 3.999
ZNF823 zinc finger protein 823 3.999
FZD8 frizzled class receptor 8 3.999
MAPK12 mitogen-activated protein kinase 12 3.999
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 3.999
B4GAT1 beta-1,4-glucuronyltransferase 1 3.999
GSAP gamma-secretase activating protein 3.999
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 3.999
CD177 CD177 molecule 3.999
TSPAN18 tetraspanin 18 3.999
ELN elastin 3.999
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4 3.999
SMAD6 SMAD family member 6 3.999
TTLL10 tubulin tyrosine ligase-like family member 10 3.999
SYNM synemin, intermediate filament protein 3.999
GPR18 G protein-coupled receptor 18 3.999
GSG1L GSG1-like 3.999
MTF1 metal-regulatory transcription factor 1 3.999
ADORA1 adenosine A1 receptor 3.999
NRM nurim (nuclear envelope membrane protein) 3.999
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 3.999
AQP5 aquaporin 5 3.999
FIMP1 fertilization-influencing membrane protein 1 3.999
GCH1 GTP cyclohydrolase 1 3.999
MOSPD2 motile sperm domain containing 2 3.999
STMN3 stathmin-like 3 3.999
LAYN layilin 3.999
HSPA1B heat shock 70kDa protein 1B 3.999
KLF5 Kruppel-like factor 5 (intestinal) 3.999
RGS16 regulator of G-protein signaling 16 3.999
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 3.999
SLC14A2 solute carrier family 14 (urea transporter), member 2 3.999
NLRC5 NLR family, CARD domain containing 5 3.999
MPND MPN domain containing 3.999
F2RL1 coagulation factor II (thrombin) receptor-like 1 3.999
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 3.999
SIT1 signaling threshold regulating transmembrane adaptor 1 3.999
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 3.999
TMEM237 transmembrane protein 237 3.88681
SNX10 sorting nexin 10 3.88681
ZC3H7B zinc finger CCCH-type containing 7B 3.88681
MAGEF1 melanoma antigen family F1 3.68359
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 3.5637
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 3.50639
DENND4A DENN/MADD domain containing 4A 3.50639
PRDM10 PR domain containing 10 3.50639
R3HCC1L R3H domain and coiled-coil containing 1-like 3.50639
BCL2 B-cell CLL/lymphoma 2 3.50639
ZNF883 zinc finger protein 883 3.50639
INTS14 integrator complex subunit 14 3.50639
HAUS2 HAUS augmin-like complex, subunit 2 3.50639
APLP1 amyloid beta (A4) precursor-like protein 1 3.49199
SYS1 Sys1 golgi trafficking protein 3.39353
DYNLT2 dynein light chain Tctex-type 2 3.39353
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 3.39353
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 3.28525
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.21876
GPATCH2L G patch domain containing 2-like 3.19136
SREBF2 sterol regulatory element binding transcription factor 2 3.18869
CDCA3 cell division cycle associated 3 3.12518
PDIA4 protein disulfide isomerase family A, member 4 3.06793
TXNDC11 thioredoxin domain containing 11 3.01431
CPQ carboxypeptidase Q 3.01431
PGM1 phosphoglucomutase 1 3.01431
COX6C cytochrome c oxidase subunit VIc 3.01431
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 2.92953
BUD13 BUD13 homolog (S. cerevisiae) 2.92953
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.92953
PCCA propionyl CoA carboxylase, alpha polypeptide 2.92313
PLPP3 phospholipid phosphatase 3 2.82827
MRE11 MRE11 homolog, double strand break repair nuclease 2.8035
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.80053
ZSCAN21 zinc finger and SCAN domain containing 21 2.80053
ICAM3 intercellular adhesion molecule 3 2.80053
NUBP1 nucleotide binding protein 1 2.80053
IL7 interleukin 7 2.80053
PCIF1 PDX1 C-terminal inhibiting factor 1 2.80053
THBS2 thrombospondin 2 2.80053
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 2.80053
CLCN6 chloride channel, voltage-sensitive 6 2.80053
MICOS13 mitochondrial contact site and cristae organizing system subunit 13 2.80053
ZNF75D zinc finger protein 75D 2.80053
PGPEP1 pyroglutamyl-peptidase I 2.80053
GAMT guanidinoacetate N-methyltransferase 2.80053
KIFBP kinesin family binding protein 2.80053
NIPAL3 NIPA-like domain containing 3 2.80053
FBXL19 F-box and leucine-rich repeat protein 19 2.80053
PRELID1 PRELI domain containing 1 2.79439
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.7896
MED21 mediator complex subunit 21 2.76327
MNS1 meiosis-specific nuclear structural 1 2.6856
RMP24 ribonuclease MRP subunit p24 2.6856
DLL1 delta-like 1 (Drosophila) 2.6856
PMFBP1 polyamine modulated factor 1 binding protein 1 2.68507
SOX8 SRY (sex determining region Y)-box 8 2.68507
OTUD1 OTU deubiquitinase 1 2.68507
NEU1 sialidase 1 (lysosomal sialidase) 2.68507
RPL14 ribosomal protein L14 2.68165
RPS12 ribosomal protein S12 2.64261
SIRAL1 SIR2 antiphage like 1 2.62511
ANXA5 annexin A5 2.56429
IGSF8 immunoglobulin superfamily, member 8 2.5549
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 2.55322
RANGAP1 Ran GTPase activating protein 1 2.47621
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 2.47621
INSIG1 insulin induced gene 1 2.47621
ZSWIM5 zinc finger, SWIM-type containing 5 2.47621
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2.47621
ATAD2B ATPase family, AAA domain containing 2B 2.45792
PGAM1 phosphoglycerate mutase 1 (brain) 2.45029
NPIPB4 nuclear pore complex interacting protein family, member B4 2.42781
SLC30A3 solute carrier family 30 (zinc transporter), member 3 2.42781
SH2D3A SH2 domain containing 3A 2.42781
MISFA mitochondrial sheath formation associated 2.42781
GMPPA GDP-mannose pyrophosphorylase A 2.42781
FAM47E family with sequence similarity 47, member E 2.42781
SPIN2B spindlin family, member 2B 2.42781
MCM9 minichromosome maintenance complex component 9 2.42781
SP8 Sp8 transcription factor 2.42781
TMEM41A transmembrane protein 41A 2.42781
PRKCG protein kinase C, gamma 2.42781
FBRS fibrosin 2.42781
CHEK1 checkpoint kinase 1 2.41473
CKAP2 cytoskeleton associated protein 2 2.39821
OXCT1 3-oxoacid CoA transferase 1 2.38935
SEC23IP SEC23 interacting protein 2.32187
SSR1 signal sequence receptor, alpha 2.31746
NCBP3 nuclear cap binding subunit 3 2.31169
PDLIM2 PDZ and LIM domain 2 (mystique) 2.30098
ILK integrin-linked kinase 2.30098
ATP5MC3 ATP synthase membrane subunit c locus 3 2.29987
HMBS hydroxymethylbilane synthase 2.26585
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 2.26157
SCGB3A2 secretoglobin, family 3A, member 2 2.26157
LAMC1 laminin, gamma 1 (formerly LAMB2) 2.25244
PPAN peter pan homolog (Drosophila) 2.2522
AQP11 aquaporin 11 2.2522
ITLN2 intelectin 2 2.2522
MTMR10 myotubularin related protein 10 2.2522
RDH16 retinol dehydrogenase 16 (all-trans) 2.2522
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 2.2522
MTSS2 MTSS I-BAR domain containing 2 2.2522
KIF21B kinesin family member 21B 2.2522
CRACD capping protein inhibiting regulator of actin dynamics 2.24613
RPL10A ribosomal protein L10a 2.21954
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.21805
TDP1 tyrosyl-DNA phosphodiesterase 1 2.18711
PSAT1 phosphoserine aminotransferase 1 2.18412
NME3 NME/NM23 nucleoside diphosphate kinase 3 2.15375
ANKHD1 ankyrin repeat and KH domain containing 1 2.15119
KCTD14 potassium channel tetramerization domain containing 14 2.14368
ZDHHC8 zinc finger, DHHC-type containing 8 2.14368
NUDC nudC nuclear distribution protein 2.14368
CKMT1B creatine kinase, mitochondrial 1B 2.14368
AKAP3 A kinase (PRKA) anchor protein 3 2.14368
LY75 lymphocyte antigen 75 2.14368
THRA thyroid hormone receptor, alpha 2.14368
S100A10 S100 calcium binding protein A10 2.14368
SRM spermidine synthase 2.14277
FBXO9 F-box protein 9 2.13085
CHEK2 checkpoint kinase 2 2.10784
RBM8A RNA binding motif protein 8A 2.10521
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 2.09958
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.0944
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 2.0781
RBM27 RNA binding motif protein 27 2.072
CAB39 calcium binding protein 39 2.06589
TRIM66 tripartite motif containing 66 2.05796
FOXK2 forkhead box K2 2.05669
ANAPC16 anaphase promoting complex subunit 16 2.0484
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.0484
VDAC2 voltage-dependent anion channel 2 2.02586
ANK1 ankyrin 1, erythrocytic 2.02322
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 2.01425
PPP1R7 protein phosphatase 1, regulatory subunit 7 2.00794
HAUS4 HAUS augmin-like complex, subunit 4 2.00794

decreased expression

Symbol Name Standardized Value
STARD4 StAR-related lipid transfer (START) domain containing 4 -3.999
PYGL phosphorylase, glycogen, liver -3.999
ZNF66 zinc finger protein 66 -3.999
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -3.999
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -3.999
ANKRD36C ankyrin repeat domain 36C -3.999
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -3.999
H2AC6 H2A clustered histone 6 -3.999
MRPL40 mitochondrial ribosomal protein L40 -3.999
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -3.85977
RAB3C RAB3C, member RAS oncogene family -3.80993
PXYLP1 2-phosphoxylose phosphatase 1 -3.54778
CABLES2 Cdk5 and Abl enzyme substrate 2 -3.50639
NEK6 NIMA-related kinase 6 -3.50639
C14ORF132 chromosome 14 open reading frame 132 -3.50639
FAM53B family with sequence similarity 53, member B -3.50639
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -3.50639
TM9SF1 transmembrane 9 superfamily member 1 -3.50639
TFIP11 tuftelin interacting protein 11 -3.50639
ADCK2 aarF domain containing kinase 2 -3.50639
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -3.50639
ANKRD35 ankyrin repeat domain 35 -3.50639
STK11IP serine/threonine kinase 11 interacting protein -3.50639
RAB19 RAB19, member RAS oncogene family -3.50639
XDH xanthine dehydrogenase -3.50639
EXOG endo/exonuclease (5'-3'), endonuclease G-like -3.50639
C1RL complement component 1, r subcomponent-like -3.50639
ANKEF1 ankyrin repeat and EF-hand domain containing 1 -3.50639
ALG12 ALG12, alpha-1,6-mannosyltransferase -3.50639
SPP1 secreted phosphoprotein 1 -3.50639
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -3.50639
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 -3.50639
PLCE1 phospholipase C, epsilon 1 -3.50639
MAST3 microtubule associated serine/threonine kinase 3 -3.50639
ENC1 ectodermal-neural cortex 1 (with BTB domain) -3.50639
SHB Src homology 2 domain containing adaptor protein B -3.50639
WDR55 WD repeat domain 55 -3.50639
PLD2 phospholipase D2 -3.50639
DUSP19 dual specificity phosphatase 19 -3.50639
EVC Ellis van Creveld protein -3.50639
SLC51A solute carrier family 51, alpha subunit -3.50639
IRS4 insulin receptor substrate 4 -3.50639
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) -3.50639
EVI5L ecotropic viral integration site 5-like -3.50639
NOL12 nucleolar protein 12 -3.50639
ZNF559 zinc finger protein 559 -3.50639
TMEM63A transmembrane protein 63A -3.50639
CHMP4C charged multivesicular body protein 4C -3.50639
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -3.50639
ERF Ets2 repressor factor -3.50639
TRABD2A TraB domain containing 2A -3.50639
NOMO3 NODAL modulator 3 -3.50639
PDGFC platelet derived growth factor C -3.50639
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D -3.50639
RAB35 RAB35, member RAS oncogene family -3.50639
COL9A3 collagen, type IX, alpha 3 -3.50639
ADGRG5 adhesion G protein-coupled receptor G5 -3.50639
ANKRD36B ankyrin repeat domain 36B -3.50639
LASP1NB LASP1 neighbor -3.50639
ZNF892 zinc finger protein 892 -3.50639
BCL3 B-cell CLL/lymphoma 3 -3.50639
FECH ferrochelatase -3.50639
POGLUT3 protein O-glucosyltransferase 3 -3.50639
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 -3.50639
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -3.50639
STEEP1 STING1 ER exit protein 1 -3.50639
UBALD1 UBA-like domain containing 1 -3.50639
DUSP18 dual specificity phosphatase 18 -3.50639
CCDC106 coiled-coil domain containing 106 -3.50639
ESYT3 extended synaptotagmin-like protein 3 -3.50639
TCTN2 tectonic family member 2 -3.50639
TSKU tsukushi, small leucine rich proteoglycan -3.50639
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -3.50639
ATP9A ATPase, class II, type 9A -3.50639
PIGH phosphatidylinositol glycan anchor biosynthesis, class H -3.50639
COL4A6 collagen, type IV, alpha 6 -3.50639
STK17B serine/threonine kinase 17b -3.50639
MTRF1 mitochondrial translational release factor 1 -3.50639
ZNF782 zinc finger protein 782 -3.50639
INAFM2 InaF-motif containing 2 -3.50639
GPR135 G protein-coupled receptor 135 -3.50639
CCDC120 coiled-coil domain containing 120 -3.50639
C1ORF94 chromosome 1 open reading frame 94 -3.50639
DMXL2 Dmx-like 2 -3.50639
CREG1 cellular repressor of E1A-stimulated genes 1 -3.50639
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -3.50639
FAM20C family with sequence similarity 20, member C -3.50639
BAHD1 bromo adjacent homology domain containing 1 -3.50639
USP3 ubiquitin specific peptidase 3 -3.39353
GTPBP8 GTP-binding protein 8 (putative) -3.3645
COL5A1 collagen, type V, alpha 1 -3.29186
NGDN neuroguidin, EIF4E binding protein -3.29186
MTG1 mitochondrial ribosome-associated GTPase 1 -3.29186
NFYC nuclear transcription factor Y, gamma -3.25089
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -3.18674
AASDH aminoadipate-semialdehyde dehydrogenase -3.18674
PMPCA peptidase (mitochondrial processing) alpha -3.17852
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -3.17852
KCNK12 potassium channel, two pore domain subfamily K, member 12 -3.13187
MKNK2 MAP kinase interacting serine/threonine kinase 2 -3.13187
PHF3 PHD finger protein 3 -3.06763
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.01439
SLC35F1 solute carrier family 35, member F1 -2.97233
ANKRD17 ankyrin repeat domain 17 -2.9309
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -2.90614
P3H1 prolyl 3-hydroxylase 1 -2.82608
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -2.82608
NRBF2 nuclear receptor binding factor 2 -2.82608
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.79867
USP1 ubiquitin specific peptidase 1 -2.7661
ARF6 ADP-ribosylation factor 6 -2.73162
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase -2.73162
NVL nuclear VCP-like -2.73162
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.71703
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -2.71703
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.71703
ZNF585B zinc finger protein 585B -2.71703
TMEM116 transmembrane protein 116 -2.71703
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -2.69745
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -2.69745
HARS1 histidyl-tRNA synthetase 1 -2.69745
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.6874
PEX5 peroxisomal biogenesis factor 5 -2.6874
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -2.6874
ERCC1 excision repair cross-complementation group 1 -2.6874
NAGLU N-acetylglucosaminidase, alpha -2.6874
TMEM43 transmembrane protein 43 -2.6874
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.68507
LOC124904942 uncharacterized LOC124904942 -2.68165
TLL2 tolloid-like 2 -2.68165
ZMYM5 zinc finger, MYM-type 5 -2.68165
USF3 upstream transcription factor family member 3 -2.68165
SCAMP2 secretory carrier membrane protein 2 -2.68165
METTL22 methyltransferase like 22 -2.68165
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -2.68165
LMO3 LIM domain only 3 (rhombotin-like 2) -2.68165
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.68165
FAM110B family with sequence similarity 110, member B -2.68165
MRPS25 mitochondrial ribosomal protein S25 -2.64168
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 -2.64168
CGAS cyclic GMP-AMP synthase -2.58403
KLHL12 kelch-like family member 12 -2.58403
KIF13B kinesin family member 13B -2.58403
LRRC1 leucine rich repeat containing 1 -2.58403
ZNF124 zinc finger protein 124 -2.5673
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF -2.5673
NOL4L nucleolar protein 4-like -2.55809
OPN3 opsin 3 -2.5525
UBE4A ubiquitination factor E4A -2.5525
SCARB2 scavenger receptor class B, member 2 -2.54896
UBE2N ubiquitin-conjugating enzyme E2N -2.44842
MBOAT2 membrane bound O-acyltransferase domain containing 2 -2.42774
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -2.41818
PLSCR1 phospholipid scramblase 1 -2.40813
SWAP70 SWAP switching B-cell complex 70kDa subunit -2.39348
RAB28 RAB28, member RAS oncogene family -2.38093
CTPS2 CTP synthase 2 -2.37532
LRRC8D leucine rich repeat containing 8 family, member D -2.35159
LEMD3 LEM domain containing 3 -2.3295
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin -2.30098
CKS2 CDC28 protein kinase regulatory subunit 2 -2.29987
TMEM200A transmembrane protein 200A -2.27953
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.27859
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -2.27753
RFWD3 ring finger and WD repeat domain 3 -2.27753
ATOX1 antioxidant 1 copper chaperone -2.24116
AGFG1 ArfGAP with FG repeats 1 -2.19701
TMX1 thioredoxin-related transmembrane protein 1 -2.16559
ACTG1 actin gamma 1 -2.14784
SASH1 SAM and SH3 domain containing 1 -2.14368
CCBE1 collagen and calcium binding EGF domains 1 -2.12475
UBA3 ubiquitin-like modifier activating enzyme 3 -2.10268
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.0781
KHDC1 KH homology domain containing 1 -2.0781
ABHD12 abhydrolase domain containing 12 -2.0781
C4ORF46 chromosome 4 open reading frame 46 -2.0781
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.06252
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -2.06252
OXR1 oxidation resistance 1 -2.05374
CHP1 calcineurin-like EF-hand protein 1 -2.02384