DD-16-GL76_0.01uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.01uM, Memantine, NMDA Antagonists targeting GRIN2A, GRIN2B (Novartis, 4054)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/4054
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Genes

3 genes differentially expressed following the DD-16-GL76_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value

decreased expression

Symbol Name Standardized Value
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.221812
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -0.218879
ASS1 argininosuccinate synthase 1 -0.218879