DD-55-SD64_0.01uM Gene Set
Genes
26 genes differentially expressed following the DD-55-SD64_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
APRT
|
adenine phosphoribosyltransferase
|
4.07526
|
|
KRT81
|
keratin 81, type II
|
3.42646
|
|
TIMM8B
|
translocase of inner mitochondrial membrane 8 homolog B (yeast)
|
0.921736
|
|
CSNK2B
|
casein kinase 2, beta polypeptide
|
0.499642
|
|
HSPB1
|
heat shock 27kDa protein 1
|
0.367028
|
|
PKMYT1
|
protein kinase, membrane associated tyrosine/threonine 1
|
0.367028
|
|
VTA1
|
vesicle (multivesicular body) trafficking 1
|
0.303157
|
|
SF3B6
|
splicing factor 3b, subunit 6, 14kDa
|
0.293368
|
|
ROMO1
|
reactive oxygen species modulator 1
|
0.246658
|
|
RRP9
|
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
|
0.229191
|
|
RPL18A
|
ribosomal protein L18a
|
0.22307
|
|
PCOLCE
|
procollagen C-endopeptidase enhancer
|
0.208542
|
|
CDC20
|
cell division cycle 20
|
0.208052
|
|
UQCR11
|
ubiquinol-cytochrome c reductase, complex III subunit XI
|
0.202541
|
|
IDH3G
|
isocitrate dehydrogenase 3 (NAD+) gamma
|
0.202541
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
JPT1
|
Jupiter microtubule associated homolog 1
|
-0.413611
|
|
TPST1
|
tyrosylprotein sulfotransferase 1
|
-0.405217
|
|
LAPTM4A
|
lysosomal protein transmembrane 4 alpha
|
-0.367028
|
|
CISD2
|
CDGSH iron sulfur domain 2
|
-0.262246
|
|
IRGQ
|
immunity-related GTPase family, Q
|
-0.253541
|
|
SMIM26
|
small integral membrane protein 26
|
-0.244117
|
|
RPL11
|
ribosomal protein L11
|
-0.214598
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
-0.208542
|
|
FBH1
|
F-box DNA helicase 1
|
-0.208052
|
|
HLA-B
|
major histocompatibility complex, class I, B
|
-0.202541
|
|
DERPC
|
DERPC proline and glycine rich nuclear protein
|
-0.201898
|
