DDB1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description damage-specific DNA binding protein 1, 127kDa|The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012] (NCBI Entrez Gene Database, 1642)
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Genes

492 genes differentially expressed following the DDB1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.48121
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.48121
RUNDC3B RUN domain containing 3B 2.48121
NCF2 neutrophil cytosolic factor 2 2.48121
SYNPO2L synaptopodin 2-like 2.48121
PCDHGB3 protocadherin gamma subfamily B, 3 2.48121
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.48121
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 2.48121
ZBTB42 zinc finger and BTB domain containing 42 2.48121
CCDC60 coiled-coil domain containing 60 2.48121
DCDC2 doublecortin domain containing 2 2.48121
CSTL1 cystatin-like 1 2.48121
DDR2 discoidin domain receptor tyrosine kinase 2 2.48121
SMIM10L2B small integral membrane protein 10 like 2B 2.48121
TRIL TLR4 interactor with leucine-rich repeats 2.48121
MITF microphthalmia-associated transcription factor 2.48121
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 2.48121
SOX8 SRY (sex determining region Y)-box 8 2.48121
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.48121
GRHL1 grainyhead-like 1 (Drosophila) 2.48121
FGF23 fibroblast growth factor 23 2.48121
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 2.48121
TP73 tumor protein p73 2.48121
VWA5B2 von Willebrand factor A domain containing 5B2 2.48121
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.48121
CELF6 CUGBP, Elav-like family member 6 2.48121
SLC16A13 solute carrier family 16, member 13 2.48121
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 2.48121
PPP1R9B protein phosphatase 1, regulatory subunit 9B 2.48121
CD160 CD160 molecule 2.48121
OR2A42 olfactory receptor, family 2, subfamily A, member 42 2.48121
COL16A1 collagen, type XVI, alpha 1 2.48121
C6ORF58 chromosome 6 open reading frame 58 2.48121
COPZ2 coatomer protein complex, subunit zeta 2 2.48121
LRRC63 leucine rich repeat containing 63 2.48121
C1R complement component 1, r subcomponent 2.48121
PTCD1 pentatricopeptide repeat domain 1 2.48121
MMP20 matrix metallopeptidase 20 2.48121
MPZ myelin protein zero 2.48121
BMP6 bone morphogenetic protein 6 2.48121
CEP126 centrosomal protein 126kDa 2.48121
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.48121
SPTB spectrin, beta, erythrocytic 2.48121
ANG angiogenin, ribonuclease, RNase A family, 5 2.48121
LHX6 LIM homeobox 6 2.48121
RNASE6 ribonuclease, RNase A family, k6 2.48121
PCDHGA12 protocadherin gamma subfamily A, 12 2.48121
DPPA3 developmental pluripotency associated 3 2.48121
MROH6 maestro heat-like repeat family member 6 2.48121
TCL1B T-cell leukemia/lymphoma 1B 2.48121
NT5DC3 5'-nucleotidase domain containing 3 2.48121
ASB14 ankyrin repeat and SOCS box containing 14 2.48121
PHKG1 phosphorylase kinase, gamma 1 (muscle) 2.48121
MORN3 MORN repeat containing 3 2.48121
FCRL5 Fc receptor-like 5 2.48121
GPR20 G protein-coupled receptor 20 2.48121
PECAM1 platelet/endothelial cell adhesion molecule 1 2.48121
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.48121
CA4 carbonic anhydrase IV 2.48121
LCN10 lipocalin 10 2.48121
RGPD4 RANBP2-like and GRIP domain containing 4 2.48121
OXCT2 3-oxoacid CoA transferase 2 2.48121
CD68 CD68 molecule 2.48121
WAS Wiskott-Aldrich syndrome 2.48121
BTN3A1 butyrophilin, subfamily 3, member A1 2.48121
SLC60A1 solute carrier family 60 member 1 2.48121
RHCE Rh blood group, CcEe antigens 2.48121
GSG1L GSG1-like 2.48121
PLCZ1 phospholipase C, zeta 1 2.48121
TMPRSS7 transmembrane protease, serine 7 2.48121
NBPF14 neuroblastoma breakpoint family, member 14 2.48121
SMTNL1 smoothelin-like 1 2.48121
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.48121
LEKR1 leucine, glutamate and lysine rich 1 2.48121
PRDM7 PR domain containing 7 2.48121
CNGA4 cyclic nucleotide gated channel alpha 4 2.48121
PMP22 peripheral myelin protein 22 2.48121
CCDC102A coiled-coil domain containing 102A 2.48121
GPR87 G protein-coupled receptor 87 2.48121
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 2.48121
RIC3 RIC3 acetylcholine receptor chaperone 2.48121
PLN phospholamban 2.48121
SLC67A1 solute carrier family 67 member 1 2.48121
TMSB15C thymosin beta 15C 2.48121
LOC107985101 uncharacterized LOC107985101 2.48121
DUSP13B dual specificity phosphatase 13B 2.48121
LOC122526780 uncharacterized LOC122526780 2.48121
RAMACL RNA guanine-7 methyltransferase activating subunit like 2.48121
DYNLT5 dynein light chain Tctex-type family member 5 2.48121
ZNF723 zinc finger protein 723 2.48121
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.48121
SPACDR sperm acrosome developmental regulator 2.48121
MINAR2 membrane integral NOTCH2 associated receptor 2 2.48121
EIPR1 EARP complex and GARP complex interacting protein 1 2.48121
GBP4 guanylate binding protein 4 2.48121
MAN2C1 mannosidase, alpha, class 2C, member 1 2.48121
STARD6 StAR-related lipid transfer (START) domain containing 6 2.48121
RBM46 RNA binding motif protein 46 2.48121
OR5H6 olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene) 2.48121
RS1 retinoschisin 1 2.48121
NCAN neurocan 2.48121
CPNE6 copine VI (neuronal) 2.48121
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.48121
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.48121
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 2.48121
CES3 carboxylesterase 3 2.48121
GUCA1B guanylate cyclase activator 1B (retina) 2.48121
CCDC144A coiled-coil domain containing 144A 2.48121
MBNL3 muscleblind-like splicing regulator 3 2.48121
FER1L6 fer-1-like family member 6 2.48121
FOXL2 forkhead box L2 2.48121
GJA4 gap junction protein, alpha 4, 37kDa 2.48121
PCDHA6 protocadherin alpha 6 2.48121
ACHE acetylcholinesterase (Yt blood group) 2.48121
RGS22 regulator of G-protein signaling 22 2.48121
RRBP1 ribosome binding protein 1 2.48121
ADGRB2 adhesion G protein-coupled receptor B2 2.48121
C1QTNF7 C1q and tumor necrosis factor related protein 7 2.48121
CFAP43 cilia and flagella associated protein 43 2.48121
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 2.48121
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.48121
SCIMP SLP adaptor and CSK interacting membrane protein 2.48121
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.48121
ACMSD aminocarboxymuconate semialdehyde decarboxylase 2.48121
BIK BCL2-interacting killer (apoptosis-inducing) 2.48121
LCAT lecithin-cholesterol acyltransferase 2.48121
IRF9 interferon regulatory factor 9 2.48121
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.48121
COL7A1 collagen, type VII, alpha 1 2.48121
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 2.48121
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 2.48121
TRIM55 tripartite motif containing 55 2.48121
TRIM58 tripartite motif containing 58 2.48121
CAGE1 cancer antigen 1 2.48121
LIMCH1 LIM and calponin homology domains 1 2.48121
C19ORF44 chromosome 19 open reading frame 44 2.48121
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.48121
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.48121
FOS FBJ murine osteosarcoma viral oncogene homolog 2.48121
CCDC73 coiled-coil domain containing 73 2.48121
CNGB3 cyclic nucleotide gated channel beta 3 2.48121
SLC45A4 solute carrier family 45, member 4 2.48121
TAS2R50 taste receptor, type 2, member 50 2.48121
DSC3 desmocollin 3 2.48121
DCLK3 doublecortin-like kinase 3 2.48121
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.48121
TBPL2 TATA box binding protein like 2 2.48121
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.48121
STAB1 stabilin 1 2.48121
DPEP3 dipeptidase 3 2.48121
CCL27 chemokine (C-C motif) ligand 27 2.48121
CCL28 chemokine (C-C motif) ligand 28 2.48121
ARHGAP20 Rho GTPase activating protein 20 2.48121
DYDC1 DPY30 domain containing 1 2.48121
POF1B premature ovarian failure, 1B 2.48121
CXCR2 chemokine (C-X-C motif) receptor 2 2.48121
CCDC74B coiled-coil domain containing 74B 2.48121
C8ORF89 chromosome 8 open reading frame 89 2.48121
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.48121
IGF1 insulin-like growth factor 1 (somatomedin C) 2.48121
ESPNL espin-like 2.48121
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.48121
ABI3 ABI family, member 3 2.48121
TM4SF19 transmembrane 4 L six family member 19 2.48121
PGLS 6-phosphogluconolactonase 2.48121
SAFB scaffold attachment factor B 2.48121
PLA2G5 phospholipase A2, group V 2.48121
TTC24 tetratricopeptide repeat domain 24 2.48121
SNAP91 synaptosomal-associated protein, 91kDa 2.48121
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.48121
BTG4 B-cell translocation gene 4 2.48121
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 2.48121
OPTC opticin 2.48121
NPTXR neuronal pentraxin receptor 2.48121
LOXHD1 lipoxygenase homology domains 1 2.48121
SPATA9 spermatogenesis associated 9 2.48121
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.48121
AMH anti-Mullerian hormone 2.48121
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2.48121
DLX2 distal-less homeobox 2 2.48121
NT5C1A 5'-nucleotidase, cytosolic IA 2.48121
PENK proenkephalin 2.48121
CTSF cathepsin F 2.48121
SLC38A3 solute carrier family 38, member 3 2.48121
FLRT3 fibronectin leucine rich transmembrane protein 3 2.48121
CCNI2 cyclin I family, member 2 2.48121
CALY calcyon neuron-specific vesicular protein 2.48121
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 2.48121
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.48121
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 2.48121
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.48121
ADAM21 ADAM metallopeptidase domain 21 2.48121
PFAS phosphoribosylformylglycinamidine synthase 2.48121
MMP10 matrix metallopeptidase 10 2.48121
PXT1 peroxisomal, testis specific 1 2.48121
JPH2 junctophilin 2 2.48121
SCTR secretin receptor 2.48121
NUTM2D NUT family member 2D 2.48121
JUN jun proto-oncogene 2.48121
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 2.48121
TMEM86A transmembrane protein 86A 2.48121
ZNF737 zinc finger protein 737 2.48121
PTCRA pre T-cell antigen receptor alpha 2.48121
LRRC38 leucine rich repeat containing 38 2.48121
CLPSL1 colipase-like 1 2.48121
ST18 suppression of tumorigenicity 18, zinc finger 2.48121
RERGL RERG/RAS-like 2.48121
PATE2 prostate and testis expressed 2 2.48121
MAEL maelstrom spermatogenic transposon silencer 2.48121
IRX3 iroquois homeobox 3 2.48121
AZIN2 antizyme inhibitor 2 2.48121
MAPK12 mitogen-activated protein kinase 12 2.48121
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.48121
NRG4 neuregulin 4 2.48121
ENDOD1 endonuclease domain containing 1 2.48121
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 2.48121
EYA2 EYA transcriptional coactivator and phosphatase 2 2.48121
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.48121
C3ORF49 chromosome 3 open reading frame 49 2.48121
LPAR6 lysophosphatidic acid receptor 6 2.48121
TSKS testis-specific serine kinase substrate 2.48121
KIF19 kinesin family member 19 2.48121
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.48121
ADIRF adipogenesis regulatory factor 2.48121
CEP162 centrosomal protein 162kDa 2.44638
USP48 ubiquitin specific peptidase 48 2.43982
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.426
LCOR ligand dependent nuclear receptor corepressor 2.426
FRMPD4 FERM and PDZ domain containing 4 2.41797
MSN moesin 2.41234
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 2.40675
SYNPO2 synaptopodin 2 2.40498
DGCR2 DiGeorge syndrome critical region gene 2 2.40498
RNF208 ring finger protein 208 2.37291
CRYL1 crystallin, lambda 1 2.37291
CPLX2 complexin 2 2.37291
ZMAT3 zinc finger, matrin-type 3 2.34594
ASTN2 astrotactin 2 2.33674
ZFYVE27 zinc finger, FYVE domain containing 27 2.31815
KIF3A kinesin family member 3A 2.28988
ZNF589 zinc finger protein 589 2.27147
LGMN legumain 2.26238
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 2.24611
FDX2 ferredoxin 2 2.23259
RNF144B ring finger protein 144B 2.23259
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.20048
FGF19 fibroblast growth factor 19 2.19426
SSR1 signal sequence receptor, alpha 2.19426
ZNF202 zinc finger protein 202 2.19391
RNF149 ring finger protein 149 2.19302
ACAT2 acetyl-CoA acetyltransferase 2 2.17885
LMCD1 LIM and cysteine-rich domains 1 2.15862
CCDC50 coiled-coil domain containing 50 2.15502
TRIM65 tripartite motif containing 65 2.15502
E2F3 E2F transcription factor 3 2.11709
IL1RAP interleukin 1 receptor accessory protein 2.1042
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 2.09232
RCAN2 regulator of calcineurin 2 2.067
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.06214
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 2.04594
ERF Ets2 repressor factor 2.04594
ARHGAP17 Rho GTPase activating protein 17 2.04452
MRPL24 mitochondrial ribosomal protein L24 2.03958
NECTIN3 nectin cell adhesion molecule 3 2.03958
CORO1B coronin, actin binding protein, 1B 2.03958
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) 2.03958
L3MBTL2 l(3)mbt-like 2 (Drosophila) 2.03958
CELF5 CUGBP, Elav-like family member 5 2.03023
VAMP7 vesicle-associated membrane protein 7 2.02649
MYO18B myosin XVIIIB 2.02564
BBS5 Bardet-Biedl syndrome 5 2.02564
AGBL1 ATP/GTP binding protein-like 1 2.02564
IGSF3 immunoglobulin superfamily, member 3 2.02564
CNRIP1 cannabinoid receptor interacting protein 1 2.02564
TSBP1 testis expressed basic protein 1 2.02564
ANKDD1B ankyrin repeat and death domain containing 1B 2.02564
GOLGA6B golgin A6 family, member B 2.02564
GPR3 G protein-coupled receptor 3 2.02564
SUSD5 sushi domain containing 5 2.02564
SCUBE3 signal peptide, CUB domain, EGF-like 3 2.02564
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 2.01136
H1-2 H1.2 linker histone, cluster member 2.00951
TMEM101 transmembrane protein 101 2.00951
MTARC1 mitochondrial amidoxime reducing component 1 2.00951
CABLES2 Cdk5 and Abl enzyme substrate 2 2.00951
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.00951
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.00951
C1QL1 complement component 1, q subcomponent-like 1 2.00951
PRLR prolactin receptor 2.00951
BARD1 BRCA1 associated RING domain 1 2.00951
IL20RB interleukin 20 receptor beta 2.00951
CLIC2 chloride intracellular channel 2 2.00951
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 2.00951
HHIPL1 HHIP-like 1 2.00951
SIX4 SIX homeobox 4 2.00951
TBC1D15 TBC1 domain family, member 15 2.00951
OSBPL7 oxysterol binding protein-like 7 2.00951
SPOUT1 SPOUT domain containing methyltransferase 1 2.00951
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 2.00951
CCDC124 coiled-coil domain containing 124 2.00434
DDB2 damage-specific DNA binding protein 2, 48kDa 2.0036
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.00168

decreased expression

Symbol Name Standardized Value
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -2.48121
ARHGAP18 Rho GTPase activating protein 18 -2.48121
ABHD16A abhydrolase domain containing 16A -2.48121
CEP43 centrosomal protein 43 -2.48121
COPS9 COP9 signalosome subunit 9 -2.48121
ELMO2 engulfment and cell motility 2 -2.48121
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -2.48121
BORCS7 BLOC-1 related complex subunit 7 -2.48121
TYW2 tRNA wybutosine-synthesizing protein 2 -2.48121
EEF2K eukaryotic elongation factor 2 kinase -2.48121
COG6 component of oligomeric golgi complex 6 -2.48121
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 -2.48121
ZNHIT2 zinc finger, HIT-type containing 2 -2.48121
ALDOA aldolase A, fructose-bisphosphate -2.48121
SERTAD2 SERTA domain containing 2 -2.48121
SMAD2 SMAD family member 2 -2.48121
DLL3 delta-like 3 (Drosophila) -2.48121
ERRFI1 ERBB receptor feedback inhibitor 1 -2.48121
TBC1D10B TBC1 domain family, member 10B -2.48121
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 -2.48121
ANKRD35 ankyrin repeat domain 35 -2.48121
RAB5IF RAB5 interacting factor -2.48121
ZBTB9 zinc finger and BTB domain containing 9 -2.48121
EAF1 ELL associated factor 1 -2.48121
ATG2A autophagy related 2A -2.48121
PJVK pejvakin -2.48121
SPAG17 sperm associated antigen 17 -2.48121
TPP1 tripeptidyl peptidase I -2.48121
RAVER1 ribonucleoprotein, PTB-binding 1 -2.48121
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -2.48121
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 -2.48121
MEGF9 multiple EGF-like-domains 9 -2.48121
DHRS13 dehydrogenase/reductase (SDR family) member 13 -2.48121
NCKAP5 NCK-associated protein 5 -2.48121
METTL4 methyltransferase like 4 -2.48121
ZNF18 zinc finger protein 18 -2.48121
TMCO4 transmembrane and coiled-coil domains 4 -2.48121
CARF calcium responsive transcription factor -2.48121
PLPPR3 phospholipid phosphatase related 3 -2.48121
TRAIP TRAF interacting protein -2.48121
CAMKV CaM kinase-like vesicle-associated -2.48121
RIT2 Ras-like without CAAX 2 -2.48121
TMEM268 transmembrane protein 268 -2.48121
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -2.47614
IFT38 intraflagellar transport 38 -2.4647
AIRIM AFG2 interacting ribosome maturation factor -2.4647
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -2.4647
TMEM94 transmembrane protein 94 -2.4647
ZBTB41 zinc finger and BTB domain containing 41 -2.4647
CEP41 centrosomal protein 41kDa -2.43252
CLCN4 chloride channel, voltage-sensitive 4 -2.42076
TMEM165 transmembrane protein 165 -2.41234
MSI2 musashi RNA-binding protein 2 -2.41234
CKS1B CDC28 protein kinase regulatory subunit 1B -2.41234
ZNF646 zinc finger protein 646 -2.41234
ZNF610 zinc finger protein 610 -2.41234
TMOD2 tropomodulin 2 (neuronal) -2.41234
GSTM4 glutathione S-transferase mu 4 -2.41234
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.40987
TRHDE thyrotropin-releasing hormone degrading enzyme -2.40675
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.3853
TOP1 topoisomerase (DNA) I -2.37291
SKIL SKI-like proto-oncogene -2.36756
GORASP2 golgi reassembly stacking protein 2, 55kDa -2.36032
ALYREF Aly/REF export factor -2.34797
RBM14 RNA binding motif protein 14 -2.33953
FKBP4 FK506 binding protein 4, 59kDa -2.33081
CENPI centromere protein I -2.32526
MED31 mediator complex subunit 31 -2.32516
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B -2.31253
GAMT guanidinoacetate N-methyltransferase -2.31253
MECR mitochondrial trans-2-enoyl-CoA reductase -2.30936
TMEM167B transmembrane protein 167B -2.30379
UBE2T ubiquitin-conjugating enzyme E2T -2.28973
MAP3K10 mitogen-activated protein kinase kinase kinase 10 -2.28715
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.28339
MCM3 minichromosome maintenance complex component 3 -2.26324
PNKP polynucleotide kinase 3'-phosphatase -2.26324
WDR62 WD repeat domain 62 -2.23678
DNM1L dynamin 1-like -2.21654
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -2.17788
C9ORF153 chromosome 9 open reading frame 153 -2.16058
COL5A3 collagen, type V, alpha 3 -2.16058
ZNF550 zinc finger protein 550 -2.16058
LIPE lipase, hormone-sensitive -2.16058
TPRA1 transmembrane protein, adipocyte asscociated 1 -2.16058
RPS6KL1 ribosomal protein S6 kinase-like 1 -2.16058
ADHFE1 alcohol dehydrogenase, iron containing, 1 -2.16058
PDE10A phosphodiesterase 10A -2.15502
L1TD1 LINE-1 type transposase domain containing 1 -2.14459
SHCBP1 SHC SH2-domain binding protein 1 -2.14459
ODAD3 outer dynein arm docking complex subunit 3 -2.14219
TMEM220 transmembrane protein 220 -2.14219
NOTCH2NLC notch 2 N-terminal like C -2.14219
RPL26 ribosomal protein L26 -2.14106
ARSG arylsulfatase G -2.13404
SCN9A sodium channel, voltage gated, type IX alpha subunit -2.12784
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -2.11709
PYGB phosphorylase, glycogen; brain -2.11475
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A -2.11243
MFSD12 major facilitator superfamily domain containing 12 -2.11168
ANO6 anoctamin 6 -2.11168
GMEB2 glucocorticoid modulatory element binding protein 2 -2.10709
DUSP16 dual specificity phosphatase 16 -2.09911
EXOSC2 exosome component 2 -2.08876
MAP3K21 mitogen-activated protein kinase kinase kinase 21 -2.08605
GPBP1 GC-rich promoter binding protein 1 -2.08605
NF2 neurofibromin 2 (merlin) -2.067
MRPL17 mitochondrial ribosomal protein L17 -2.067
ZNF148 zinc finger protein 148 -2.06214
CDC14A cell division cycle 14A -2.04452
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.03958
KLRG2 killer cell lectin-like receptor subfamily G, member 2 -2.03958
ROR1 receptor tyrosine kinase-like orphan receptor 1 -2.03044
RNF166 ring finger protein 166 -2.02649
MANBA mannosidase, beta A, lysosomal -2.02564
JTB jumping translocation breakpoint -2.02432
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -2.01136
FAM78A family with sequence similarity 78, member A -2.00951
HLA-DRA major histocompatibility complex, class II, DR alpha -2.00951
NR1I2 nuclear receptor subfamily 1, group I, member 2 -2.00951
COMMD8 COMM domain containing 8 -2.00951
H2BC4 H2B clustered histone 4 -2.00951
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit -2.00951
ZPR1 ZPR1 zinc finger -2.00951
DPP7 dipeptidyl-peptidase 7 -2.00951
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 -2.00951
XKR5 XK, Kell blood group complex subunit-related family, member 5 -2.00951
TNNC2 troponin C type 2 (fast) -2.00951
PNLIPRP2 pancreatic lipase-related protein 2 -2.00951
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.00951
FAM13C family with sequence similarity 13, member C -2.00951
ZNF70 zinc finger protein 70 -2.00951
TOMM70 translocase of outer mitochondrial membrane 70 -2.00951
UBXN6 UBX domain protein 6 -2.00951
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.00951
IRF6 interferon regulatory factor 6 -2.00951
ADRA2B adrenoceptor alpha 2B -2.00951
JAKMIP3 Janus kinase and microtubule interacting protein 3 -2.00951
DCLK2 doublecortin-like kinase 2 -2.00951
DXO decapping exoribonuclease -2.00951
CCDC159 coiled-coil domain containing 159 -2.00951
CAV2 caveolin 2 -2.00951
SMNDC1 survival motor neuron domain containing 1 -2.00951
ITLN2 intelectin 2 -2.00951
PNMT phenylethanolamine N-methyltransferase -2.00951
USP30 ubiquitin specific peptidase 30 -2.00951
SYTL5 synaptotagmin-like 5 -2.00951
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 -2.00951
RPL7 ribosomal protein L7 -2.00951
KLHL42 kelch-like family member 42 -2.00951
ENO3 enolase 3 (beta, muscle) -2.00951
FBXO17 F-box protein 17 -2.00951
WNT3 wingless-type MMTV integration site family, member 3 -2.00951
MTM1 myotubularin 1 -2.00951
SPRYD3 SPRY domain containing 3 -2.00951
PLD6 phospholipase D family, member 6 -2.00951
KBTBD3 kelch repeat and BTB (POZ) domain containing 3 -2.00951
RASL11A RAS-like, family 11, member A -2.00951
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 -2.00951
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -2.00951
TDRD12 tudor domain containing 12 -2.00951
TTC32 tetratricopeptide repeat domain 32 -2.00951
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -2.00951
ZNF408 zinc finger protein 408 -2.00951
CLDND2 claudin domain containing 2 -2.00951
PLSCR4 phospholipid scramblase 4 -2.00951
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -2.00951
HEXIM1 hexamethylene bis-acetamide inducible 1 -2.00951
TNNT2 troponin T type 2 (cardiac) -2.00951
NXPH2 neurexophilin 2 -2.00951
RXFP1 relaxin/insulin-like family peptide receptor 1 -2.00951
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 -2.00951
TMPRSS11E transmembrane protease, serine 11E -2.00951
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -2.00951
TJP3 tight junction protein 3 -2.00951
TNS3 tensin 3 -2.00951
MOGAT1 monoacylglycerol O-acyltransferase 1 -2.00951
APLP1 amyloid beta (A4) precursor-like protein 1 -2.00951
SSPN sarcospan -2.00951
PGM2L1 phosphoglucomutase 2-like 1 -2.00951
PDE8A phosphodiesterase 8A -2.00951
VENTX VENT homeobox -2.00951
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) -2.00951
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.00951
TSFM Ts translation elongation factor, mitochondrial -2.00951
KLHL28 kelch-like family member 28 -2.00951
FOXL2NB FOXL2 neighbor -2.00951
PTPRN protein tyrosine phosphatase, receptor type, N -2.00951
RPS12 ribosomal protein S12 -2.00168