DDR1-IN-1 Gene Set
Genes
19 genes differentially expressed following the DDR1-IN-1 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
6.91109
|
|
INSIG1
|
insulin induced gene 1
|
5.34351
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
4.97365
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
4.02844
|
|
HSD17B7
|
hydroxysteroid (17-beta) dehydrogenase 7
|
3.9913
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
3.8905
|
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
3.8745
|
|
FDPS
|
farnesyl diphosphate synthase
|
3.79202
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
3.7754
|
|
FADS1
|
fatty acid desaturase 1
|
3.59375
|
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
3.50567
|
|
MSMO1
|
methylsterol monooxygenase 1
|
3.46899
|
|
SQSTM1
|
sequestosome 1
|
3.4023
|
|
PNPLA3
|
patatin-like phospholipase domain containing 3
|
3.34627
|
|
ACAT2
|
acetyl-CoA acetyltransferase 2
|
3.31316
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
3.27816
|
|
MVD
|
mevalonate (diphospho) decarboxylase
|
3.00527
|
|
PHLDA2
|
pleckstrin homology-like domain, family A, member 2
|
3.00338
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CLCA4
|
chloride channel accessory 4
|
-3.04818
|
