DDT Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A chlorophenylethane that is 1,1,1-trichloro-2,2-diphenylethane substituted by additional chloro substituents at positions 4 of the phenyl substituents. It is a commonly used organochlorine insecticide. (Chemical Entities of Biological Interest Ontology, CHEBI_16130)
External Link http://ctdbase.org/detail.go?type=chem&acc=D003634
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Genes

73 genes/proteins interacting with the chemical DDT from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AR androgen receptor
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A cytochrome P450, family 3, subfamily A
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DNMT1 DNA (cytosine-5-)-methyltransferase 1
E2F1 E2F transcription factor 1
EGF epidermal growth factor
ELK1 ELK1, member of ETS oncogene family
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
G6PD glucose-6-phosphate dehydrogenase
GADD45B growth arrest and DNA-damage-inducible, beta
GGT1 gamma-glutamyltransferase 1
GJA1 gap junction protein, alpha 1, 43kDa
GJB1 gap junction protein, beta 1, 32kDa
GPER1 G protein-coupled estrogen receptor 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
IL2 interleukin 2
IL4 interleukin 4
JAK1 Janus kinase 1
JUN jun proto-oncogene
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MT2A metallothionein 2A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH1 notch 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
PGR progesterone receptor
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
RB1 retinoblastoma 1
RXRB retinoid X receptor, beta
SHBG sex hormone-binding globulin
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SOS1 son of sevenless homolog 1 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TSHR thyroid stimulating hormone receptor
VIM vimentin