DDX11 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11|DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1663)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DDX11
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Genes

197 co-expressed genes for DDX11 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACAD11 acyl-CoA dehydrogenase family, member 11
ADAM15 ADAM metallopeptidase domain 15
ADAMTSL2 ADAMTS-like 2
ADD2 adducin 2 (beta)
AGER advanced glycosylation end product-specific receptor
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
ALDOC aldolase C, fructose-bisphosphate
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKRD12 ankyrin repeat domain 12
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AQP5 aquaporin 5
ARSE arylsulfatase E (chondrodysplasia punctata 1)
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BAHD1 bromo adjacent homology domain containing 1
BCL2 B-cell CLL/lymphoma 2
BPHL biphenyl hydrolase-like (serine hydrolase)
BTD biotinidase
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD10 caspase recruitment domain family, member 10
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD8B CD8b molecule
CDK13 cyclin-dependent kinase 13
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHD3 chromodomain helicase DNA binding protein 3
CIZ1 CDKN1A interacting zinc finger protein 1
CLP1 cleavage and polyadenylation factor I subunit 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTN2 contactin 2 (axonal)
COL11A2 collagen, type XI, alpha 2
COMMD2 COMM domain containing 2
COPS7A COP9 signalosome subunit 7A
COQ10A coenzyme Q10 homolog A (S. cerevisiae)
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRCP CGRP receptor component
CRHR2 corticotropin releasing hormone receptor 2
CRYBA4 crystallin, beta A4
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DBNL drebrin-like
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DENND4A DENN/MADD domain containing 4A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPT dermatopontin
ECE2 endothelin converting enzyme 2
EIF5B eukaryotic translation initiation factor 5B
EML3 echinoderm microtubule associated protein like 3
EXTL3 exostosin-like glycosyltransferase 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM189A2 family with sequence similarity 189, member A2
FAM189B family with sequence similarity 189, member B
FANCG Fanconi anemia, complementation group G
FDXR ferredoxin reductase
FKBP15 FK506 binding protein 15, 133kDa
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GCAT glycine C-acetyltransferase
GFM2 G elongation factor, mitochondrial 2
GGT7 gamma-glutamyltransferase 7
GHITM growth hormone inducible transmembrane protein
GIGYF1 GRB10 interacting GYF protein 1
GLYCTK glycerate kinase
GPR35 G protein-coupled receptor 35
GRIK5 glutamate receptor, ionotropic, kainate 5
GRK4 G protein-coupled receptor kinase 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAUS5 HAUS augmin-like complex, subunit 5
HMG20B high mobility group 20B
HMGXB3 HMG box domain containing 3
HNRNPL heterogeneous nuclear ribonucleoprotein L
HSF4 heat shock transcription factor 4
HSPB2 heat shock 27kDa protein 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFT140 intraflagellar transport 140
IGHMBP2 immunoglobulin mu binding protein 2
IGSF9B immunoglobulin superfamily, member 9B
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
KAT8 K(lysine) acetyltransferase 8
KHNYN KH and NYN domain containing
KIAA0195 KIAA0195
KIFC3 kinesin family member C3
KLHL18 kelch-like family member 18
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRT2 keratin 2, type II
KRT85 keratin 85, type II
LSM1 LSM1, U6 small nuclear RNA associated
LSM12 LSM12 homolog (S. cerevisiae)
LTK leukocyte receptor tyrosine kinase
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCRS1 microspherule protein 1
MEF2D myocyte enhancer factor 2D
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MKS1 Meckel syndrome, type 1
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MR1 major histocompatibility complex, class I-related
MSX1 msh homeobox 1
MT4 metallothionein 4
MTX1 metaxin 1
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYO9B myosin IXB
NCKIPSD NCK interacting protein with SH3 domain
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NELFB negative elongation factor complex member B
NFRKB nuclear factor related to kappaB binding protein
NFYB nuclear transcription factor Y, beta
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
PAX8 paired box 8
PCBP3 poly(rC) binding protein 3
PCGF1 polycomb group ring finger 1
PFDN1 prefoldin subunit 1
PHB prohibitin
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLIN3 perilipin 3
PMF1 polyamine-modulated factor 1
PML promyelocytic leukemia
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKCSH protein kinase C substrate 80K-H
PRKD2 protein kinase D2
PRPH peripherin
PRSS16 protease, serine, 16 (thymus)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PVT1 Pvt1 oncogene (non-protein coding)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RANBP2 RAN binding protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP8 retinoblastoma binding protein 8
RBM8A RNA binding motif protein 8A
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPA2 replication protein A2, 32kDa
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RTBDN retbindin
S100PBP S100P binding protein
SCAMP2 secretory carrier membrane protein 2
SEC24A SEC24 family member A
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SETD1B SET domain containing 1B
SFSWAP splicing factor, suppressor of white-apricot family
SH2B1 SH2B adaptor protein 1
SIK3 SIK family kinase 3
SIN3A SIN3 transcription regulator family member A
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A24 solute carrier family 22, member 24
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMG5 SMG5 nonsense mediated mRNA decay factor
SPEF1 sperm flagellar 1
SPPL2B signal peptide peptidase like 2B
SPTB spectrin, beta, erythrocytic
SSTR5 somatostatin receptor 5
STAT5B signal transducer and activator of transcription 5B
TADA2B transcriptional adaptor 2B
TBCD tubulin folding cofactor D
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEX261 testis expressed 261
TEX28 testis expressed 28
THRAP3 thyroid hormone receptor associated protein 3
TLN2 talin 2
TM4SF5 transmembrane 4 L six family member 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNP1 transition protein 1 (during histone to protamine replacement)
TPR translocated promoter region, nuclear basket protein
TRA2A transformer 2 alpha homolog (Drosophila)
TSPO2 translocator protein 2
TTI1 TELO2 interacting protein 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
URGCP upregulator of cell proliferation
USP19 ubiquitin specific peptidase 19
USP6 ubiquitin specific peptidase 6
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR5 WD repeat domain 5
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
WWOX WW domain containing oxidoreductase
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592