DDX58 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description DEAD (Asp-Glu-Ala-Asp) box polypeptide 58|DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23586)
External Link http://www.ncbi.nlm.nih.gov/gene/23586
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203 interacting proteins for DDX58 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
AHNAK AHNAK nucleoprotein
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANXA11 annexin A11
ANXA2 annexin A2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARF1 ADP-ribosylation factor 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL2 ADP-ribosylation factor-like 2
ATG12 autophagy related 12
ATG5 autophagy related 5
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
AXIN1 axin 1
BAG6 BCL2-associated athanogene 6
C11ORF48
CAND1 cullin-associated and neddylation-dissociated 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD46 CD46 molecule, complement regulatory protein
CD9 CD9 molecule
CFL1 cofilin 1 (non-muscle)
CHMP2A charged multivesicular body protein 2A
CHUK conserved helix-loop-helix ubiquitous kinase
CLTC clathrin, heavy chain (Hc)
COMMD5 COMM domain containing 5
COPB1 coatomer protein complex, subunit beta 1
COPZ1 coatomer protein complex, subunit zeta 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSK c-src tyrosine kinase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYLD cylindromatosis (turban tumor syndrome)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNM1L dynamin 1-like
DNM2 dynamin 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
ENO1 enolase 1, (alpha)
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EZR ezrin
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
FNTA farnesyltransferase, CAAX box, alpha
FUK fucokinase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPA33 glycoprotein A33 (transmembrane)
GSK3B glycogen synthase kinase 3 beta
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HNF4A hepatocyte nuclear factor 4, alpha
IFRD1 interferon-related developmental regulator 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IPO5 importin 5
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF5B kinesin family member 5B
KLC1 kinesin light chain 1
KPNB1 karyopherin (importin) beta 1
LASP1 LIM and SH3 protein 1
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
LGALS4 lectin, galactoside-binding, soluble, 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAVS mitochondrial antiviral signaling protein
MAX MYC associated factor X
MBP myelin basic protein
MEX3C mex-3 RNA binding family member C
MSN moesin
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
NCAPG non-SMC condensin I complex, subunit G
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT1 one cut homeobox 1
OTUD5 OTU deubiquitinase 5
PCNA proliferating cell nuclear antigen
PDCD10 programmed cell death 10
PDS5A PDS5 cohesin associated factor A
PHGDH phosphoglycerate dehydrogenase
PKM pyruvate kinase, muscle
PLAA phospholipase A2-activating protein
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEC plectin
PPL periplakin
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP5C protein phosphatase 5, catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCG protein kinase C, gamma
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
RAB11A RAB11A, member RAS oncogene family
RAB15 RAB15, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAI14 retinoic acid induced 14
RAN RAN, member RAS oncogene family
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RCC2 regulator of chromosome condensation 2
RDX radixin
RIPK2 receptor-interacting serine-threonine kinase 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF135 ring finger protein 135
RNF31 ring finger protein 31
RPS27A ribosomal protein S27a
SART3 squamous cell carcinoma antigen recognized by T cells 3
SEC31A SEC31 homolog A (S. cerevisiae)
SELENBP1 selenium binding protein 1
SEPT2 septin 2
SEPT7 septin 7
SEPT9 septin 9
SET SET nuclear proto-oncogene
SETD3 SET domain containing 3
SH3GL2 SH3-domain GRB2-like 2
SNX1 sorting nexin 1
SNX2 sorting nexin 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP68 signal recognition particle 68kDa
SRP72 signal recognition particle 72kDa
STAT1 signal transducer and activator of transcription 1, 91kDa
STIP1 stress-induced phosphoprotein 1
STX3 syntaxin 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBK1 TANK-binding kinase 1
TFRC transferrin receptor
TKFC triokinase/FMN cyclase
TLN1 talin 1
TMEM173 transmembrane protein 173
TNPO1 transportin 1
TPM3 tropomyosin 3
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TRIM26 tripartite motif containing 26
TRIM28 tripartite motif containing 28
TRIM32 tripartite motif containing 32
TSPAN6 tetraspanin 6
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA7 ubiquitin-like modifier activating enzyme 7
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2O ubiquitin-conjugating enzyme E2O
UBE4A ubiquitination factor E4A
UBQLN1 ubiquilin 1
UBQLN2 ubiquilin 2
UBXN1 UBX domain protein 1
USO1 USO1 vesicle transport factor
USP18 ubiquitin specific peptidase 18
USP21 ubiquitin specific peptidase 21
USP3 ubiquitin specific peptidase 3
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP41 ubiquitin specific peptidase 41
VSNL1 visinin-like 1
WNK1 WNK lysine deficient protein kinase 1
WRNIP1 Werner helicase interacting protein 1
XPO1 exportin 1
XPO4 exportin 4
XPO5 exportin 5
XPO7 exportin 7
XPOT exportin, tRNA
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZWILCH zwilch kinetochore protein