DE-15-GD59_0.01uM Gene Set
Genes
33 genes differentially expressed following the DE-15-GD59_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADAMTS19
|
ADAM metallopeptidase with thrombospondin type 1 motif, 19
|
2.52689
|
|
APRT
|
adenine phosphoribosyltransferase
|
2.23979
|
|
OST4
|
oligosaccharyltransferase 4 homolog (S. cerevisiae)
|
2.12017
|
|
UBA52
|
ubiquitin A-52 residue ribosomal protein fusion product 1
|
1.46578
|
|
MYL2
|
myosin, light chain 2, regulatory, cardiac, slow
|
0.689679
|
|
PPDPF
|
pancreatic progenitor cell differentiation and proliferation factor
|
0.655291
|
|
RPS7
|
ribosomal protein S7
|
0.597604
|
|
C19ORF33
|
chromosome 19 open reading frame 33
|
0.560174
|
|
FAU
|
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
|
0.556595
|
|
RPS11
|
ribosomal protein S11
|
0.556595
|
|
RPL28
|
ribosomal protein L28
|
0.556595
|
|
TIMM8B
|
translocase of inner mitochondrial membrane 8 homolog B (yeast)
|
0.53821
|
|
NDUFA11
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
|
0.475605
|
|
CST3
|
cystatin C
|
0.309748
|
|
RPS19
|
ribosomal protein S19
|
0.307472
|
|
CRYAB
|
crystallin, alpha B
|
0.303772
|
|
POLR2F
|
polymerase (RNA) II (DNA directed) polypeptide F
|
0.28343
|
|
CDC20
|
cell division cycle 20
|
0.28343
|
|
ROMO1
|
reactive oxygen species modulator 1
|
0.282227
|
|
UQCR11
|
ubiquinol-cytochrome c reductase, complex III subunit XI
|
0.260822
|
|
PSMD12
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
|
0.230377
|
|
SF3B6
|
splicing factor 3b, subunit 6, 14kDa
|
0.230311
|
|
NANS
|
N-acetylneuraminic acid synthase
|
0.220667
|
|
CRB3
|
crumbs family member 3
|
0.218694
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
RACGAP1
|
Rac GTPase activating protein 1
|
-0.556595
|
|
RGMB
|
repulsive guidance molecule family member b
|
-0.408583
|
|
HNRNPAB
|
heterogeneous nuclear ribonucleoprotein A/B
|
-0.338439
|
|
DNMT1
|
DNA (cytosine-5-)-methyltransferase 1
|
-0.274896
|
|
MCM3
|
minichromosome maintenance complex component 3
|
-0.259389
|
|
VPS26B
|
vacuolar protein sorting 26 homolog B (S. pombe)
|
-0.259375
|
|
FOXP4
|
forkhead box P4
|
-0.259097
|
|
CDK5RAP1
|
CDK5 regulatory subunit associated protein 1
|
-0.218694
|
|
HLA-B
|
major histocompatibility complex, class I, B
|
-0.206475
|
