DE-15-GD59_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM (Novartis)
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Genes

20 genes differentially expressed following the DE-15-GD59_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.18972
C19ORF33 chromosome 19 open reading frame 33 1.02852
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.8664
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 0.841218
RPL36 ribosomal protein L36 0.745389
RPL8 ribosomal protein L8 0.670747
APRT adenine phosphoribosyltransferase 0.670747
RPL37 ribosomal protein L37 0.492407
RPL28 ribosomal protein L28 0.467441
RPL35 ribosomal protein L35 0.444059
CST3 cystatin C 0.440413
RPS9 ribosomal protein S9 0.368081
LGALS1 lectin, galactoside-binding, soluble, 1 0.267453
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.266239
RPS11 ribosomal protein S11 0.235673
RPS15 ribosomal protein S15 0.23522
RPL19 ribosomal protein L19 0.221701
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.20232
ROMO1 reactive oxygen species modulator 1 0.200831

decreased expression

Symbol Name Standardized Value
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -0.463836