DE-60-SD92_0.01uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.01uM, Lamotrigine (Novartis, 3878)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/3878
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Genes

14 genes differentially expressed following the DE-60-SD92_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
RPS27L ribosomal protein S27-like 0.37911
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.318428
DDTL D-dopachrome tautomerase-like 0.318428
RPS23 ribosomal protein S23 0.302237
RPS12 ribosomal protein S12 0.269424
MZT1 mitotic spindle organizing protein 1 0.213967
COMMD6 COMM domain containing 6 0.209347

decreased expression

Symbol Name Standardized Value
CABIN1 calcineurin binding protein 1 -0.309877
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.309877
UBAP2 ubiquitin associated protein 2 -0.309877
ENDOV endonuclease V -0.268391
SGSM3 small G protein signaling modulator 3 -0.235587
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.200785
AURKB aurora kinase B -0.200785