DE-60-SD92_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM, Lamotrigine (Novartis, 3878)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/3878
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Genes

8 genes differentially expressed following the DE-60-SD92_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
BEX2 brain expressed X-linked 2 0.405531
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.260017
XAGE1A X antigen family member 1A 0.240818
RPS13 ribosomal protein S13 0.209008

decreased expression

Symbol Name Standardized Value
LRRC37B leucine rich repeat containing 37B -0.562166
PACS2 phosphofurin acidic cluster sorting protein 2 -0.562166
MYD88 myeloid differentiation primary response 88 -0.331042
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -0.240818