DEK Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description DEK proto-oncogene|This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 7913)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DEK
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Genes

296 co-expressed genes for DEK from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ACAA2 acetyl-CoA acyltransferase 2
ACLY ATP citrate lyase
ACP1 acid phosphatase 1, soluble
ACYP1 acylphosphatase 1, erythrocyte (common) type
AFG3L2 AFG3-like AAA ATPase 2
ANAPC5 anaphase promoting complex subunit 5
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
AURKB aurora kinase B
BANF1 barrier to autointegration factor 1
BCL7B B-cell CLL/lymphoma 7B
BRD8 bromodomain containing 8
BUB3 BUB3 mitotic checkpoint protein
BZW1 basic leucine zipper and W2 domains 1
C1QBP complement component 1, q subcomponent binding protein
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CANX calnexin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CBX3 chromobox homolog 3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC123 cell division cycle 123
CDK2 cyclin-dependent kinase 2
CEP57 centrosomal protein 57kDa
CHERP calcium homeostasis endoplasmic reticulum protein
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLTC clathrin, heavy chain (Hc)
CNBP CCHC-type zinc finger, nucleic acid binding protein
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COPS3 COP9 signalosome subunit 3
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
COX7B cytochrome c oxidase subunit VIIb
COX7C cytochrome c oxidase subunit VIIc
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CS citrate synthase
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTDNEP1 CTD nuclear envelope phosphatase 1
CUL1 cullin 1
CYC1 cytochrome c-1
DAP3 death associated protein 3
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DEK DEK proto-oncogene
DGUOK deoxyguanosine kinase
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DOCK3 dedicator of cytokinesis 3
DRG1 developmentally regulated GTP binding protein 1
DUT deoxyuridine triphosphatase
EBP emopamil binding protein (sterol isomerase)
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A2 eukaryotic translation initiation factor 4A2
EIF4H eukaryotic translation initiation factor 4H
ERH enhancer of rudimentary homolog (Drosophila)
ETF1 eukaryotic translation termination factor 1
EXOSC8 exosome component 8
FAM120A family with sequence similarity 120A
FAM168B family with sequence similarity 168, member B
FBL fibrillarin
FBXW11 F-box and WD repeat domain containing 11
FOXJ3 forkhead box J3
FUS FUS RNA binding protein
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GANAB glucosidase, alpha; neutral AB
GBAS glioblastoma amplified sequence
GDI2 GDP dissociation inhibitor 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPN1 GPN-loop GTPase 1
H2AFV H2A histone family, member V
H2AFZ H2A histone family, member Z
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAT1 histone acetyltransferase 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA8 heat shock 70kDa protein 8
HSPB11 heat shock protein family B (small), member 11
HTATSF1 HIV-1 Tat specific factor 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICE1 interactor of little elongation complex ELL subunit 1
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFRD1 interferon-related developmental regulator 1
IK IK cytokine, down-regulator of HLA II
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IST1 increased sodium tolerance 1 homolog (yeast)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
JTB jumping translocation breakpoint
KARS lysyl-tRNA synthetase
KDM3B lysine (K)-specific demethylase 3B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0101 KIAA0101
KIF2A kinesin heavy chain member 2A
KRIT1 KRIT1, ankyrin repeat containing
LDHA lactate dehydrogenase A
LRPPRC leucine-rich pentatricopeptide repeat containing
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MCM2 minichromosome maintenance complex component 2
MCM5 minichromosome maintenance complex component 5
MDH1 malate dehydrogenase 1, NAD (soluble)
METAP1 methionyl aminopeptidase 1
MRPL9 mitochondrial ribosomal protein L9
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTDH metadherin
NACA nascent polypeptide-associated complex alpha subunit
NAP1L1 nucleosome assembly protein 1-like 1
NAP1L4 nucleosome assembly protein 1-like 4
NCL nucleolin
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NONO non-POU domain containing, octamer-binding
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP153 nucleoporin 153kDa
NUP188 nucleoporin 188kDa
NUP50 nucleoporin 50kDa
OXA1L oxidase (cytochrome c) assembly 1-like
PAPOLA poly(A) polymerase alpha
PARK7 parkinson protein 7
PCBP2 poly(rC) binding protein 2
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCNA proliferating cell nuclear antigen
PDS5A PDS5 cohesin associated factor A
PGK1 phosphoglycerate kinase 1
PHB2 prohibitin 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POM121 POM121 transmembrane nucleoporin
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRMT1 protein arginine methyltransferase 1
PRPF31 pre-mRNA processing factor 31
PRPF8 pre-mRNA processing factor 8
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRRC2C proline-rich coiled-coil 2C
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PTBP1 polypyrimidine tract binding protein 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
PUF60 poly-U binding splicing factor 60KDa
PUM1 pumilio RNA-binding family member 1
PUM2 pumilio RNA-binding family member 2
R3HDM1 R3H domain containing 1
RAD21 RAD21 homolog (S. pombe)
RAD23A RAD23 homolog A (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALY RALY heterogeneous nuclear ribonucleoprotein
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RBMX RNA binding motif protein, X-linked
RFC4 replication factor C (activator 1) 4, 37kDa
RHEB Ras homolog enriched in brain
RNPS1 RNA binding protein S1, serine-rich domain
RPA1 replication protein A1, 70kDa
RPL21 ribosomal protein L21
RPL36AL ribosomal protein L36a-like
RPL6 ribosomal protein L6
RPS27A ribosomal protein S27a
RTN4 reticulon 4
SAFB scaffold attachment factor B
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SEC63 SEC63 homolog (S. cerevisiae)
SEPT7 septin 7
SERBP1 SERPINE1 mRNA binding protein 1
SERP1 stress-associated endoplasmic reticulum protein 1
SET SET nuclear proto-oncogene
SFPQ splicing factor proline/glutamine-rich
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SKP1 S-phase kinase-associated protein 1
SLBP stem-loop binding protein
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMC1A structural maintenance of chromosomes 1A
SMC4 structural maintenance of chromosomes 4
SMNDC1 survival motor neuron domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNW1 SNW domain containing 1
SOD1 superoxide dismutase 1, soluble
SON SON DNA binding protein
SP3 Sp3 transcription factor
SREBF2 sterol regulatory element binding transcription factor 2
SRI sorcin
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP72 signal recognition particle 72kDa
SRP9 signal recognition particle 9kDa
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF9 serine/arginine-rich splicing factor 9
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAG2 stromal antigen 2
STARD7 StAR-related lipid transfer (START) domain containing 7
STK24 serine/threonine kinase 24
STOML2 stomatin (EPB72)-like 2
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYPL1 synaptophysin-like 1
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TARDBP TAR DNA binding protein
TCEA1 transcription elongation factor A (SII), 1
TDG thymine-DNA glycosylase
TERF2IP telomeric repeat binding factor 2, interacting protein
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMEM123 transmembrane protein 123
TOP1 topoisomerase (DNA) I
TOP1P2 topoisomerase (DNA) I pseudogene 2
TOPBP1 topoisomerase (DNA) II binding protein 1
TRA2B transformer 2 beta homolog (Drosophila)
TRAPPC3 trafficking protein particle complex 3
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
TUG1 taurine up-regulated 1 (non-protein coding)
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2SURP U2 snRNP-associated SURP domain containing
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UQCRH ubiquinol-cytochrome c reductase hinge protein
USP1 ubiquitin specific peptidase 1
VBP1 von Hippel-Lindau binding protein 1
VDAC2 voltage-dependent anion channel 2
VRK1 vaccinia related kinase 1
XPO1 exportin 1
XPO6 exportin 6
XPO7 exportin 7
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H15 zinc finger CCCH-type containing 15
ZCCHC8 zinc finger, CCHC domain containing 8
ZZZ3 zinc finger, ZZ-type containing 3