DENR Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description density-regulated protein|This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8562)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GCM_DENR
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Genes

98 co-expressed genes for DENR from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD16A abhydrolase domain containing 16A
ACAD11 acyl-CoA dehydrogenase family, member 11
ACOT8 acyl-CoA thioesterase 8
AK4 adenylate kinase 4
ALKBH5 AlkB family member 5, RNA demethylase
ANAPC5 anaphase promoting complex subunit 5
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
BCAS2 breast carcinoma amplified sequence 2
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BRD8 bromodomain containing 8
C14ORF1 chromosome 14 open reading frame 1
C1ORF52 chromosome 1 open reading frame 52
CCAR1 cell division cycle and apoptosis regulator 1
CCDC59 coiled-coil domain containing 59
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHUK conserved helix-loop-helix ubiquitous kinase
COMMD9 COMM domain containing 9
COPB1 coatomer protein complex, subunit beta 1
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CS citrate synthase
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DENND4A DENN/MADD domain containing 4A
DENR density-regulated protein
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
EIF3A eukaryotic translation initiation factor 3, subunit A
EXOSC8 exosome component 8
FUS FUS RNA binding protein
GATAD2A GATA zinc finger domain containing 2A
GFM2 G elongation factor, mitochondrial 2
GPBP1 GC-rich promoter binding protein 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPB11 heat shock protein family B (small), member 11
INTS8 integrator complex subunit 8
IPO5 importin 5
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MBD3 methyl-CpG binding domain protein 3
MCM4 minichromosome maintenance complex component 4
MED17 mediator complex subunit 17
MORF4L1 mortality factor 4 like 1
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MRPL9 mitochondrial ribosomal protein L9
MRPS10 mitochondrial ribosomal protein S10
MTDH metadherin
MTMR4 myotubularin related protein 4
MTMR7 myotubularin related protein 7
NF2 neurofibromin 2 (merlin)
PABPN1 poly(A) binding protein, nuclear 1
PAPOLA poly(A) polymerase alpha
PCNP PEST proteolytic signal containing nuclear protein
PDS5A PDS5 cohesin associated factor A
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PRPF8 pre-mRNA processing factor 8
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTMA prothymosin, alpha
QARS glutaminyl-tRNA synthetase
RBM15 RNA binding motif protein 15
RBMX RNA binding motif protein, X-linked
REPIN1 replication initiator 1
RWDD1 RWD domain containing 1
S100PBP S100P binding protein
SIN3A SIN3 transcription regulator family member A
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMNDC1 survival motor neuron domain containing 1
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRP19 signal recognition particle 19kDa
SRP72 signal recognition particle 72kDa
SSB Sjogren syndrome antigen B (autoantigen La)
SUMF2 sulfatase modifying factor 2
SUMO2 small ubiquitin-like modifier 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TARDBP TAR DNA binding protein
TBC1D14 TBC1 domain family, member 14
TEX261 testis expressed 261
TMEM167B transmembrane protein 167B
TMEM39B transmembrane protein 39B
TOPBP1 topoisomerase (DNA) II binding protein 1
TOR1AIP1 torsin A interacting protein 1
TRA2B transformer 2 beta homolog (Drosophila)
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
XPO1 exportin 1
ZC3H15 zinc finger CCCH-type containing 15
ZNF146 zinc finger protein 146
ZNF22 zinc finger protein 22
ZNF317 zinc finger protein 317