DIMENHYDRINATE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description The diphenhydramine salt of 8-chlorotheophylline. Its effects are similar to those of diphenhydramine, but it is less potent. It was thought that by combining the antiemetic effects of diphenhydramine with the mild stimulant effects of 8-chlorotheophyline, the extreme drowsiness induced by the former would be mitigated. However, the sedation caused by diphenhydramine is considerably stronger than the stimulation caused by 8-chlorotheophylline. Dimenhydrinate is used mainly as an antiemetic in the prevention and treatment of motion sickness. (Chemical Entities of Biological Interest Ontology, CHEBI_4604)
External Link https://dgidb.org/results?searchType=drug&searchTerms=DIMENHYDRINATE
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Genes

2 interacting proteins for the DIMENHYDRINATE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
HRH1 histamine receptor H1 0.548518
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.0433159