| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | dihydrolipoamide dehydrogenase|This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 1738) |
| External Link | https://ncbi.nlm.nih.gov/gene/1738 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the DLD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0117568 |
| SFTPB | surfactant protein B | 0.0114242 |
| SFTPA2 | surfactant protein A2 | 0.0113143 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0112943 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0108874 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0104131 |
| NKX2-1 | NK2 homeobox 1 | 0.00922303 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00913194 |
| SFTPC | surfactant protein C | 0.00834476 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00825049 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00823248 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00815355 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00806087 |
| MMP12 | matrix metallopeptidase 12 | 0.00776285 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0074696 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 0.00730962 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00730235 |
| FMO3 | flavin containing monooxygenase 3 | 0.00704696 |
| AQP9 | aquaporin 9 | 0.00697615 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.00686503 |
| SFTPD | surfactant protein D | 0.00668708 |
| GNAS | GNAS complex locus | 0.0066582 |
| TOX3 | TOX high mobility group box family member 3 | 0.0066112 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00657746 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00655138 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00655131 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00652455 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00651815 |
| TMSB15A | thymosin beta 15a | 0.0064922 |
| SMYD2 | SET and MYND domain containing 2 | 0.00634101 |
| HMGB2 | high mobility group box 2 | 0.00634023 |
| MAP7 | microtubule-associated protein 7 | 0.00625577 |
| STK26 | serine/threonine protein kinase 26 | 0.00618813 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00618533 |
| ODAM | odontogenic, ameloblast asssociated | 0.00613796 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | 0.00611027 |
| ANOS1 | anosmin 1 | 0.00610535 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.00608504 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00606842 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00603987 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00589321 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0058576 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00584126 |
| SQLE | squalene epoxidase | 0.00574919 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00572453 |
| C4BPA | complement component 4 binding protein, alpha | 0.00569144 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.00567192 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00565211 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00564273 |
| PDGFC | platelet derived growth factor C | 0.0056217 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00561007 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00559676 |
| RBPMS | RNA binding protein with multiple splicing | 0.00547157 |
| IL6R | interleukin 6 receptor | 0.00542016 |
| ACKR3 | atypical chemokine receptor 3 | 0.0053985 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00538989 |
| C2 | complement component 2 | 0.00535005 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00533587 |
| LECT2 | leukocyte cell-derived chemotaxin 2 | 0.00531636 |
| ZNF589 | zinc finger protein 589 | 0.00530584 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00530432 |
| DESI1 | desumoylating isopeptidase 1 | 0.0052667 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00525604 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | 0.00523711 |
| PCNA | proliferating cell nuclear antigen | 0.00522489 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00520969 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00520909 |
| AHSG | alpha-2-HS-glycoprotein | 0.00520011 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00518386 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00517166 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00516286 |
| GATA2 | GATA binding protein 2 | 0.00515333 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00505352 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00502571 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00502135 |
| FOXA2 | forkhead box A2 | 0.00501802 |
| TCF12 | transcription factor 12 | 0.0050174 |
| CPB2 | carboxypeptidase B2 (plasma) | 0.00500335 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.00499932 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00499836 |
| GSTT1 | glutathione S-transferase theta 1 | 0.0049967 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00498493 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | 0.00498165 |
| RNF43 | ring finger protein 43 | 0.00497554 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00497357 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | 0.0049445 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00492458 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00492384 |
| COL1A2 | collagen, type I, alpha 2 | 0.00491984 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00491402 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00490808 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0048948 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00488829 |
| ESR1 | estrogen receptor 1 | 0.00485512 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.00485419 |
| ASGR1 | asialoglycoprotein receptor 1 | 0.0048525 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00484526 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00483752 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00481003 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00477924 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00477764 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0047742 |
| APOA1 | apolipoprotein A-I | 0.0047693 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00476465 |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.00475935 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.00474589 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00474453 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00474024 |
| ABI1 | abl-interactor 1 | 0.00472913 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00472548 |
| SMAD7 | SMAD family member 7 | 0.00470321 |
| APOA2 | apolipoprotein A-II | 0.00469322 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00467618 |
| APOC1 | apolipoprotein C-I | 0.00466374 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00465598 |
| TLK2 | tousled-like kinase 2 | 0.00464751 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00464418 |
| DACH1 | dachshund family transcription factor 1 | 0.00461426 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 0.00460143 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 0.00458858 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00458248 |
| DCLK1 | doublecortin-like kinase 1 | 0.0045761 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00457272 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.00456314 |
| GTF3A | general transcription factor IIIA | 0.00453873 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | 0.00452909 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00449745 |
| CEP57 | centrosomal protein 57kDa | 0.00448661 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.00446937 |
| GSAP | gamma-secretase activating protein | 0.00445937 |
| YME1L1 | YME1-like 1 ATPase | 0.00445822 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00445178 |
| CST1 | cystatin SN | 0.00445006 |
| CLTA | clathrin, light chain A | 0.00444291 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00444165 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00442269 |
| ZNF544 | zinc finger protein 544 | 0.00442015 |
| APOC2 | apolipoprotein C-II | 0.0044099 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | 0.00440505 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00440161 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00439329 |
| HPR | haptoglobin-related protein | 0.00438966 |
| F2 | coagulation factor II (thrombin) | 0.0043887 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00438635 |
| MORF4L2 | mortality factor 4 like 2 | 0.00438062 |
| FZD5 | frizzled class receptor 5 | 0.00437893 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00437537 |
| ASGR2 | asialoglycoprotein receptor 2 | 0.00437242 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.00436363 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00436337 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00435757 |
| RGS16 | regulator of G-protein signaling 16 | 0.00435374 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00434351 |
| PIPOX | pipecolic acid oxidase | 0.00434321 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.00431777 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00431421 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00429134 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00427188 |
| EFNB2 | ephrin-B2 | 0.00426107 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | 0.00425144 |
| DIO1 | deiodinase, iodothyronine, type I | 0.00424776 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00422888 |
| OXTR | oxytocin receptor | 0.00422469 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00422049 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00421936 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0042097 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00420796 |
| CTSE | cathepsin E | 0.00420618 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0042054 |
| RPL14 | ribosomal protein L14 | 0.00419767 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00419534 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.00419497 |
| ITIH1 | inter-alpha-trypsin inhibitor heavy chain 1 | 0.00419422 |
| LASP1 | LIM and SH3 protein 1 | 0.00418821 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00418189 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | 0.00417623 |
| PARK7 | parkinson protein 7 | 0.00416034 |
| DAPK1 | death-associated protein kinase 1 | 0.00415993 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | 0.00414707 |
| HPCAL1 | hippocalcin-like 1 | 0.0041442 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00413952 |
| FRY | furry homolog (Drosophila) | 0.00413303 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00412078 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00411959 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00411571 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00411392 |
| DAD1 | defender against cell death 1 | 0.00411028 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | 0.0041089 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00409074 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00408409 |
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.00407014 |
| NONO | non-POU domain containing, octamer-binding | 0.00406599 |
| HLA-A | major histocompatibility complex, class I, A | 0.00406252 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00405573 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.0040367 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00403577 |
| SHROOM2 | shroom family member 2 | 0.00402654 |
| TRIM2 | tripartite motif containing 2 | 0.0040032 |
| ITSN2 | intersectin 2 | 0.00399943 |
| AUTS2 | autism susceptibility candidate 2 | 0.00398557 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00398101 |
| GLS | glutaminase | 0.00397965 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00396349 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.00395029 |
| PON3 | paraoxonase 3 | 0.00394037 |
| FMO5 | flavin containing monooxygenase 5 | 0.00393517 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00393487 |
| PROX1 | prospero homeobox 1 | 0.00391223 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00390868 |
| PGC | progastricsin (pepsinogen C) | 0.0039043 |
| CCDC28A | coiled-coil domain containing 28A | 0.00390136 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00389728 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.00389459 |
| LIPC | lipase, hepatic | 0.0038891 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | 0.00387456 |
| KLHL24 | kelch-like family member 24 | 0.00386309 |
| RAB14 | RAB14, member RAS oncogene family | 0.00386151 |
| RAB38 | RAB38, member RAS oncogene family | 0.00385742 |
| LBH | limb bud and heart development | 0.00385631 |
| ADI1 | acireductone dioxygenase 1 | 0.0038442 |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 0.00384006 |
| ZNF638 | zinc finger protein 638 | 0.00381923 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00380563 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00380554 |
| RORA | RAR-related orphan receptor A | 0.00379837 |
| CTSC | cathepsin C | 0.00378971 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00378793 |
| CLSTN2 | calsyntenin 2 | 0.00378748 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0037874 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00378494 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.00378434 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00378052 |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 | 0.00377752 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | 0.00377742 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.00376849 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.0037625 |
| ODC1 | ornithine decarboxylase 1 | 0.00375947 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.00375145 |
| CREB5 | cAMP responsive element binding protein 5 | 0.00374775 |
| GPC4 | glypican 4 | 0.00374684 |
| RPS8 | ribosomal protein S8 | 0.00374534 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00373997 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 0.0037397 |
| EIF2D | eukaryotic translation initiation factor 2D | 0.00373718 |
| QDPR | quinoid dihydropteridine reductase | 0.0037339 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00372375 |
| HMGB1 | high mobility group box 1 | 0.00372001 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.00371747 |
| ENAH | enabled homolog (Drosophila) | 0.00371671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLD | dihydrolipoamide dehydrogenase | -0.0391482 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0199824 |
| CA2 | carbonic anhydrase II | -0.0190109 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0147461 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.014078 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0137473 |
| G0S2 | G0/G1 switch 2 | -0.0133341 |
| CFD | complement factor D (adipsin) | -0.0129709 |
| LAMB1 | laminin, beta 1 | -0.0129676 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0126602 |
| S100A9 | S100 calcium binding protein A9 | -0.0117601 |
| LTF | lactotransferrin | -0.0113515 |
| XIC | X chromosome inactivation center | -0.0110596 |
| S100P | S100 calcium binding protein P | -0.010932 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0106555 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0106499 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00985542 |
| S100A7 | S100 calcium binding protein A7 | -0.00956216 |
| AREG | amphiregulin | -0.00945455 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00931271 |
| CSTA | cystatin A (stefin A) | -0.00930589 |
| DEFB1 | defensin, beta 1 | -0.00925635 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00914165 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00893177 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0089202 |
| MMD | monocyte to macrophage differentiation-associated | -0.0088815 |
| C3 | complement component 3 | -0.00883644 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00875247 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00866261 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00851813 |
| INAVA | innate immunity activator | -0.00847397 |
| KYNU | kynureninase | -0.00841768 |
| NELL1 | NEL-like 1 (chicken) | -0.00829656 |
| PODXL | podocalyxin-like | -0.00827676 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00825751 |
| CAV2 | caveolin 2 | -0.00814736 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00810575 |
| LCN2 | lipocalin 2 | -0.00809427 |
| BCAP29 | B-cell receptor-associated protein 29 | -0.00804854 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00800878 |
| DMXL2 | Dmx-like 2 | -0.00798274 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00791369 |
| COG5 | component of oligomeric golgi complex 5 | -0.00789611 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00788493 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00775998 |
| C7 | complement component 7 | -0.00769209 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00767807 |
| PRAME | preferentially expressed antigen in melanoma | -0.00766459 |
| PSCA | prostate stem cell antigen | -0.00765025 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0076209 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00756849 |
| KRT19 | keratin 19, type I | -0.00754383 |
| FLNA | filamin A, alpha | -0.00752644 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00751764 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00745297 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 | -0.0074399 |
| ANK2 | ankyrin 2, neuronal | -0.00743584 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | -0.00743298 |
| PLAT | plasminogen activator, tissue | -0.00737873 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00737326 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00731068 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00730552 |
| GPM6B | glycoprotein M6B | -0.00729545 |
| PEG3 | paternally expressed 3 | -0.00729522 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00725392 |
| NPY1R | neuropeptide Y receptor Y1 | -0.007225 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00721865 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00721469 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00719718 |
| SRPK2 | SRSF protein kinase 2 | -0.00719489 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | -0.00713399 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00711289 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00705343 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00705227 |
| MGLL | monoglyceride lipase | -0.00704214 |
| RHOF | ras homolog family member F (in filopodia) | -0.00701681 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -0.00701069 |
| MCL1 | myeloid cell leukemia 1 | -0.00699239 |
| THBS4 | thrombospondin 4 | -0.00699205 |
| ADD3 | adducin 3 (gamma) | -0.00695574 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00692704 |
| KRT14 | keratin 14, type I | -0.00685719 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00685317 |
| NPTX2 | neuronal pentraxin II | -0.0068318 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00681409 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00677258 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00671841 |
| CRYAB | crystallin, alpha B | -0.00663515 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | -0.00658274 |
| CD93 | CD93 molecule | -0.00657466 |
| PMPCB | peptidase (mitochondrial processing) beta | -0.0065657 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00650118 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0064706 |
| TFF1 | trefoil factor 1 | -0.00643281 |
| DUSP5 | dual specificity phosphatase 5 | -0.00641888 |
| NRCAM | neuronal cell adhesion molecule | -0.0063372 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00631826 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00631405 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.00627437 |
| PLP1 | proteolipid protein 1 | -0.00625503 |
| THBS1 | thrombospondin 1 | -0.00619062 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00617067 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00616735 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00615099 |
| REG1A | regenerating islet-derived 1 alpha | -0.00614386 |
| SYNM | synemin, intermediate filament protein | -0.00613633 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.00610562 |
| AGR2 | anterior gradient 2 | -0.00606163 |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | -0.00606116 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00605794 |
| PTEN | phosphatase and tensin homolog | -0.00597593 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00597276 |
| THBD | thrombomodulin | -0.00594696 |
| SCG5 | secretogranin V | -0.00594281 |
| FCGBP | Fc fragment of IgG binding protein | -0.0059324 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00592103 |
| S100A8 | S100 calcium binding protein A8 | -0.00589762 |
| CTSG | cathepsin G | -0.00587935 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.00587154 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00585011 |
| CLDN10 | claudin 10 | -0.00584494 |
| FAM13B | family with sequence similarity 13, member B | -0.00584216 |
| IRF8 | interferon regulatory factor 8 | -0.00583072 |
| MXRA5 | matrix-remodelling associated 5 | -0.00582091 |
| TOB1 | transducer of ERBB2, 1 | -0.00580529 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00580359 |
| SRGN | serglycin | -0.0058031 |
| MATN2 | matrilin 2 | -0.00579827 |
| BICC1 | BicC family RNA binding protein 1 | -0.00579627 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00578658 |
| GPX3 | glutathione peroxidase 3 | -0.00575992 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00575255 |
| STK17A | serine/threonine kinase 17a | -0.00574682 |
| PNMA8A | PNMA family member 8A | -0.00573087 |
| ACO2 | aconitase 2, mitochondrial | -0.00570404 |
| ADIRF | adipogenesis regulatory factor | -0.0057006 |
| EPHB4 | EPH receptor B4 | -0.00569693 |
| PDE8A | phosphodiesterase 8A | -0.00569474 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00565457 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00562462 |
| OGN | osteoglycin | -0.00562355 |
| MALL | mal, T-cell differentiation protein-like | -0.00561327 |
| PLIN1 | perilipin 1 | -0.00561229 |
| EPHB6 | EPH receptor B6 | -0.00558541 |
| CLU | clusterin | -0.00557404 |
| ANXA10 | annexin A10 | -0.00553852 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00553156 |
| BEX4 | brain expressed, X-linked 4 | -0.00552333 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.00550398 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00550256 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0054993 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00548333 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00548324 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00546783 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00545459 |
| TMEM168 | transmembrane protein 168 | -0.00545034 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00544659 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00544638 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00543439 |
| LHFP | lipoma HMGIC fusion partner | -0.00542371 |
| ZNF277 | zinc finger protein 277 | -0.00542283 |
| PFKM | phosphofructokinase, muscle | -0.00541661 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.00539416 |
| CA12 | carbonic anhydrase XII | -0.00538112 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00534686 |
| RGS1 | regulator of G-protein signaling 1 | -0.00534599 |
| EGR2 | early growth response 2 | -0.00534589 |
| C1S | complement component 1, s subcomponent | -0.00532056 |
| ORC5 | origin recognition complex, subunit 5 | -0.00530812 |
| PITX3 | paired-like homeodomain 3 | -0.00530754 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00530386 |
| MYOT | myotilin | -0.00529622 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00528494 |
| MRPS33 | mitochondrial ribosomal protein S33 | -0.00526398 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00526178 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00525649 |
| KIF2A | kinesin heavy chain member 2A | -0.0052291 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00522865 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00522594 |
| GPR137B | G protein-coupled receptor 137B | -0.00522529 |
| TMEM255A | transmembrane protein 255A | -0.0052244 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.005212 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00520589 |
| VCAN | versican | -0.00519368 |
| CNN3 | calponin 3, acidic | -0.00518297 |
| KLK8 | kallikrein-related peptidase 8 | -0.00518036 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00517917 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00514339 |
| NEFM | neurofilament, medium polypeptide | -0.00511102 |
| TRRAP | transformation/transcription domain-associated protein | -0.00510209 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00510035 |
| LDB2 | LIM domain binding 2 | -0.00509816 |
| S100B | S100 calcium binding protein B | -0.00509441 |
| MAGEA3 | melanoma antigen family A3 | -0.00508646 |
| MAL | mal, T-cell differentiation protein | -0.00506374 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00505859 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00504253 |
| ARF5 | ADP-ribosylation factor 5 | -0.0050297 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00502602 |
| KLF10 | Kruppel-like factor 10 | -0.00499569 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00497456 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00495617 |
| PUS7 | pseudouridylate synthase 7 (putative) | -0.00492025 |
| KRT17 | keratin 17, type I | -0.00491144 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00490865 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0048895 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -0.00487758 |
| KRT81 | keratin 81, type II | -0.00487297 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00486534 |
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | -0.00485452 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00485202 |
| IL7R | interleukin 7 receptor | -0.00485173 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -0.00484354 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.00484037 |
| COPS6 | COP9 signalosome subunit 6 | -0.00482103 |
| C21ORF33 | chromosome 21 open reading frame 33 | -0.00481753 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00481321 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00480495 |
| ADCY3 | adenylate cyclase 3 | -0.00480021 |
| MMP7 | matrix metallopeptidase 7 | -0.00479909 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00479281 |
| KRT13 | keratin 13, type I | -0.00477717 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00476874 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00475557 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00473151 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | -0.00472501 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00472056 |
| NUTF2 | nuclear transport factor 2 | -0.00471814 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0047165 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00471132 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00470071 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00469524 |
| CYC1 | cytochrome c-1 | -0.00469343 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -0.00469112 |
| PRKCA | protein kinase C, alpha | -0.00468688 |
| ATF3 | activating transcription factor 3 | -0.00468007 |
| PMP2 | peripheral myelin protein 2 | -0.00467233 |
| NMD3 | NMD3 ribosome export adaptor | -0.00465446 |
| OLFML3 | olfactomedin-like 3 | -0.00462951 |
| DLAT | dihydrolipoamide S-acetyltransferase | -0.00462898 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00462819 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | -0.00461353 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.00459731 |
| CYTIP | cytohesin 1 interacting protein | -0.00457987 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00457292 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -0.00456954 |
| MDFIC | MyoD family inhibitor domain containing | -0.00456068 |
| RINT1 | RAD50 interactor 1 | -0.00455022 |
| ARL14 | ADP-ribosylation factor-like 14 | -0.0045482 |
