| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | dystrophin|The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1756) |
| External Link | https://ncbi.nlm.nih.gov/gene/1756 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the DMD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPB1 | heat shock 27kDa protein 1 | 0.0231048 |
| MAGEA3 | melanoma antigen family A3 | 0.0182712 |
| MMP1 | matrix metallopeptidase 1 | 0.0152814 |
| KRT14 | keratin 14, type I | 0.0145827 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0142654 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.0142269 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0134758 |
| NNMT | nicotinamide N-methyltransferase | 0.0134345 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.0133661 |
| KRT17 | keratin 17, type I | 0.0130868 |
| CYTH1 | cytohesin 1 | 0.0129106 |
| PLXNC1 | plexin C1 | 0.0124466 |
| CEL | carboxyl ester lipase | 0.0123698 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.012285 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0121405 |
| TENM3 | teneurin transmembrane protein 3 | 0.0117274 |
| RGS16 | regulator of G-protein signaling 16 | 0.0115565 |
| MAGEA12 | melanoma antigen family A12 | 0.0114335 |
| TCTA | T-cell leukemia translocation altered | 0.0114292 |
| ASS1 | argininosuccinate synthase 1 | 0.0112488 |
| CCNA2 | cyclin A2 | 0.0111164 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0107854 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0105586 |
| KRT16 | keratin 16, type I | 0.0105393 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0100941 |
| LOX | lysyl oxidase | 0.0100132 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0100098 |
| S100A2 | S100 calcium binding protein A2 | 0.00975636 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00940962 |
| TNC | tenascin C | 0.00937234 |
| GNAS | GNAS complex locus | 0.00928712 |
| TXLNA | taxilin alpha | 0.00921643 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00918373 |
| PEG10 | paternally expressed 10 | 0.00903848 |
| PMP22 | peripheral myelin protein 22 | 0.00901465 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00900161 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00891309 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 0.00889137 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00888804 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00876579 |
| CLTB | clathrin, light chain B | 0.00876404 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00874049 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00870826 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00870806 |
| TGFB1 | transforming growth factor, beta 1 | 0.00868581 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00867499 |
| MAGEA1 | melanoma antigen family A1 | 0.00865678 |
| PLS3 | plastin 3 | 0.00864005 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00860022 |
| MMP9 | matrix metallopeptidase 9 | 0.00859589 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0085847 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00855764 |
| SNAI2 | snail family zinc finger 2 | 0.0085108 |
| STK10 | serine/threonine kinase 10 | 0.00849557 |
| TGFB3 | transforming growth factor, beta 3 | 0.00849429 |
| KLF2 | Kruppel-like factor 2 | 0.00844335 |
| MAEA | macrophage erythroblast attacher | 0.00833378 |
| REXO2 | RNA exonuclease 2 | 0.0083032 |
| KLF6 | Kruppel-like factor 6 | 0.0082777 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00822225 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.00817356 |
| PLXNA1 | plexin A1 | 0.00815228 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | 0.00808408 |
| EGR1 | early growth response 1 | 0.00807511 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00801842 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00800659 |
| CCN2 | cellular communication network factor 2 | 0.00793789 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00787539 |
| NOTCH1 | notch 1 | 0.00782787 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00780295 |
| INHBA | inhibin, beta A | 0.00779468 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0077718 |
| SCGN | secretagogin, EF-hand calcium binding protein | 0.00776085 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00775819 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00775781 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00774439 |
| GOLGA8A | golgin A8 family, member A | 0.00771118 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00770506 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00768788 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00767385 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00765294 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00763477 |
| KLK5 | kallikrein-related peptidase 5 | 0.00763111 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00761795 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0075798 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00752342 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0074697 |
| MIR22HG | MIR22 host gene | 0.00746634 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00744997 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | 0.00743854 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00740823 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0073724 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00734104 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00733549 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00732239 |
| RRBP1 | ribosome binding protein 1 | 0.00732148 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00731708 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00730964 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00726525 |
| LPIN1 | lipin 1 | 0.00724735 |
| GCH1 | GTP cyclohydrolase 1 | 0.0072435 |
| CDC20 | cell division cycle 20 | 0.00722278 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00721998 |
| POSTN | periostin, osteoblast specific factor | 0.00721902 |
| CA12 | carbonic anhydrase XII | 0.00721843 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00721664 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00719924 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.0071853 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00716951 |
| ADM | adrenomedullin | 0.00714857 |
| SST | somatostatin | 0.00712839 |
| AURKB | aurora kinase B | 0.00707589 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.00705787 |
| AK1 | adenylate kinase 1 | 0.00705238 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00705105 |
| AEBP1 | AE binding protein 1 | 0.0070308 |
| C1S | complement component 1, s subcomponent | 0.00702288 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00699984 |
| COL3A1 | collagen, type III, alpha 1 | 0.00699272 |
| LMNA | lamin A/C | 0.00697945 |
| THBS2 | thrombospondin 2 | 0.00697513 |
| CAPN15 | calpain 15 | 0.00695121 |
| FSTL1 | follistatin-like 1 | 0.00694672 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00693161 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00692874 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00692023 |
| PDZD2 | PDZ domain containing 2 | 0.00691604 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00687525 |
| COLEC12 | collectin sub-family member 12 | 0.0068479 |
| NEFM | neurofilament, medium polypeptide | 0.00682717 |
| XAF1 | XIAP associated factor 1 | 0.00682361 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00680701 |
| PLXND1 | plexin D1 | 0.00680407 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.006797 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 0.00678454 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00678367 |
| XPO6 | exportin 6 | 0.00675972 |
| ACTN4 | actinin, alpha 4 | 0.00674596 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00674409 |
| TSKU | tsukushi, small leucine rich proteoglycan | 0.00673236 |
| DSP | desmoplakin | 0.00671777 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00671655 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00670766 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00670714 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00670029 |
| MMP11 | matrix metallopeptidase 11 | 0.00667709 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) | 0.00665918 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00665013 |
| CBX1 | chromobox homolog 1 | 0.00663998 |
| PLK2 | polo-like kinase 2 | 0.00663747 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.00662145 |
| RAPSN | receptor-associated protein of the synapse | 0.00662106 |
| RCAN3 | RCAN family member 3 | 0.00660399 |
| PPL | periplakin | 0.00659741 |
| COMP | cartilage oligomeric matrix protein | 0.00658102 |
| GAS6 | growth arrest-specific 6 | 0.00656235 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00654994 |
| NSUN5 | NOP2/Sun domain family, member 5 | 0.00654934 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00653108 |
| ZNF512B | zinc finger protein 512B | 0.0064984 |
| SPHK1 | sphingosine kinase 1 | 0.00649243 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00648297 |
| DROSHA | drosha, ribonuclease type III | 0.00644811 |
| PCGF3 | polycomb group ring finger 3 | 0.00641386 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00640108 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | 0.00639268 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00637774 |
| FZD2 | frizzled class receptor 2 | 0.00637596 |
| TBCD | tubulin folding cofactor D | 0.00636098 |
| CCNL2 | cyclin L2 | 0.00635059 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00634166 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00633622 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00632627 |
| KRT6B | keratin 6B, type II | 0.00632483 |
| EGR3 | early growth response 3 | 0.00632154 |
| AIM2 | absent in melanoma 2 | 0.00632129 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00631891 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00630229 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00629732 |
| CSK | c-src tyrosine kinase | 0.00627948 |
| BSG | basigin (Ok blood group) | 0.00625699 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.00625255 |
| LUC7L | LUC7-like (S. cerevisiae) | 0.00623653 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00621685 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00620477 |
| CD320 | CD320 molecule | 0.0061887 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00618842 |
| ANGPT1 | angiopoietin 1 | 0.00618152 |
| TTR | transthyretin | 0.00617723 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 0.00616672 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 0.0061249 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.0061089 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | 0.00610648 |
| COL5A1 | collagen, type V, alpha 1 | 0.00610634 |
| CENPT | centromere protein T | 0.0061011 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00610108 |
| PAX6 | paired box 6 | 0.006101 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.00609861 |
| GLS | glutaminase | 0.00609427 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00608504 |
| SPRR1A | small proline-rich protein 1A | 0.00608491 |
| STAB1 | stabilin 1 | 0.00608463 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.00607945 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00607767 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00607655 |
| SPRR1B | small proline-rich protein 1B | 0.00604532 |
| KRT7 | keratin 7, type II | 0.00603683 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.00602869 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00602173 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00602099 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00601779 |
| COL1A1 | collagen, type I, alpha 1 | 0.00601718 |
| RUNX3 | runt-related transcription factor 3 | 0.00601646 |
| CHERP | calcium homeostasis endoplasmic reticulum protein | 0.00601348 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.00601227 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.00601184 |
| PFN2 | profilin 2 | 0.00600495 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00598151 |
| SPRR2B | small proline-rich protein 2B | 0.00598088 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00597844 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00597825 |
| SPATA20 | spermatogenesis associated 20 | 0.00597498 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.0059741 |
| HES1 | hes family bHLH transcription factor 1 | 0.00597234 |
| DUSP2 | dual specificity phosphatase 2 | 0.00597039 |
| RGS4 | regulator of G-protein signaling 4 | 0.00596872 |
| MX2 | MX dynamin-like GTPase 2 | 0.00596518 |
| ADCY7 | adenylate cyclase 7 | 0.00595648 |
| PNN | pinin, desmosome associated protein | 0.00595461 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00595313 |
| KIAA0125 | KIAA0125 | 0.00595172 |
| FBN2 | fibrillin 2 | 0.00591314 |
| DLX2 | distal-less homeobox 2 | 0.00589896 |
| CBS | cystathionine-beta-synthase | 0.0058954 |
| SMAD7 | SMAD family member 7 | 0.00589469 |
| MTA1 | metastasis associated 1 | 0.00588947 |
| STK25 | serine/threonine kinase 25 | 0.00588341 |
| FBLN2 | fibulin 2 | 0.00588219 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00587801 |
| THOC6 | THO complex 6 | 0.00587401 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00586694 |
| MGLL | monoglyceride lipase | 0.00586543 |
| FAM193B | family with sequence similarity 193, member B | 0.00584949 |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit | 0.00584107 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00583884 |
| FAM160B2 | family with sequence similarity 160, member B2 | 0.00583593 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00582544 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00581922 |
| KRT23 | keratin 23, type I | 0.00581327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0196214 |
| MSMB | microseminoprotein, beta- | -0.015026 |
| MPO | myeloperoxidase | -0.0129247 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0119318 |
| ADD3 | adducin 3 (gamma) | -0.0116084 |
| MAOA | monoamine oxidase A | -0.011275 |
| CD9 | CD9 molecule | -0.0110861 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.0110442 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0109866 |
| ACP3 | acid phosphatase 3 | -0.0108282 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.0108057 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0106958 |
| FABP7 | fatty acid binding protein 7, brain | -0.0103255 |
| KRT13 | keratin 13, type I | -0.00999807 |
| S100P | S100 calcium binding protein P | -0.00999324 |
| OLFM4 | olfactomedin 4 | -0.00985514 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00982746 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00980144 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00978463 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00972054 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00970954 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00970438 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.0096902 |
| METRN | meteorin, glial cell differentiation regulator | -0.00964035 |
| RGCC | regulator of cell cycle | -0.00963646 |
| ANXA3 | annexin A3 | -0.00961035 |
| PLN | phospholamban | -0.00955181 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00937344 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00935048 |
| SERINC5 | serine incorporator 5 | -0.0093456 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00929858 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00925281 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00917877 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00912602 |
| OAT | ornithine aminotransferase | -0.00904009 |
| EPCAM | epithelial cell adhesion molecule | -0.00890075 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00888187 |
| SORD | sorbitol dehydrogenase | -0.00876854 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00863429 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00861024 |
| MYBPC1 | myosin binding protein C, slow type | -0.00849401 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00848829 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00847737 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.0084463 |
| PDE8B | phosphodiesterase 8B | -0.0084192 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00840019 |
| TARP | TCR gamma alternate reading frame protein | -0.00838057 |
| NEBL | nebulette | -0.00833537 |
| FOXC1 | forkhead box C1 | -0.00832435 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00829458 |
| GPM6B | glycoprotein M6B | -0.00827847 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00822507 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.0082218 |
| AGR2 | anterior gradient 2 | -0.00820597 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00811582 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00808366 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00807862 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00804297 |
| ANXA1 | annexin A1 | -0.00803786 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00799595 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00798331 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00798081 |
| EHF | ets homologous factor | -0.00796708 |
| AOC1 | amine oxidase, copper containing 1 | -0.00792963 |
| CUX2 | cut-like homeobox 2 | -0.00792067 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0078135 |
| IRS2 | insulin receptor substrate 2 | -0.00780292 |
| RLN2 | relaxin 2 | -0.00776569 |
| LTF | lactotransferrin | -0.0077385 |
| SLC35E3 | solute carrier family 35, member E3 | -0.00773822 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.00771776 |
| TSPAN1 | tetraspanin 1 | -0.00771389 |
| LDB3 | LIM domain binding 3 | -0.00770168 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00763792 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.00761586 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00754651 |
| ARG2 | arginase 2 | -0.00754185 |
| MGP | matrix Gla protein | -0.00753297 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00750415 |
| MT1M | metallothionein 1M | -0.00745037 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00741478 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00740895 |
| FBXO11 | F-box protein 11 | -0.00739733 |
| RAG1 | recombination activating gene 1 | -0.0073303 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00731266 |
| STK39 | serine threonine kinase 39 | -0.00729327 |
| PON2 | paraoxonase 2 | -0.00728324 |
| DAZAP2 | DAZ associated protein 2 | -0.00728085 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00727405 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0072483 |
| AREG | amphiregulin | -0.00724699 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00724642 |
| CFD | complement factor D (adipsin) | -0.00724482 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.00723278 |
| KLK2 | kallikrein-related peptidase 2 | -0.0072253 |
| BMP7 | bone morphogenetic protein 7 | -0.00722082 |
| TERF2 | telomeric repeat binding factor 2 | -0.00721883 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00719601 |
| CLDN8 | claudin 8 | -0.00717543 |
| EGR2 | early growth response 2 | -0.0071578 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00714907 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00714797 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00714602 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00713601 |
| TGM2 | transglutaminase 2 | -0.00712883 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00712505 |
| H2AFV | H2A histone family, member V | -0.00712073 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00711304 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00710006 |
| LEFTY1 | left-right determination factor 1 | -0.00706701 |
| CTBP2 | C-terminal binding protein 2 | -0.00706169 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00703176 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00702681 |
| PLP1 | proteolipid protein 1 | -0.00701062 |
| GRAMD1C | GRAM domain containing 1C | -0.00697823 |
| TOR1A | torsin family 1, member A (torsin A) | -0.00693823 |
| CSTA | cystatin A (stefin A) | -0.00693784 |
| GFAP | glial fibrillary acidic protein | -0.00693783 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00691967 |
| LIPT1 | lipoyltransferase 1 | -0.00690994 |
| WWOX | WW domain containing oxidoreductase | -0.00684822 |
| SALL1 | spalt-like transcription factor 1 | -0.00684538 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00684467 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00681702 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0068164 |
| FHL1 | four and a half LIM domains 1 | -0.00678337 |
| ADRA2A | adrenoceptor alpha 2A | -0.00677452 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0067429 |
| PMP2 | peripheral myelin protein 2 | -0.00673405 |
| CD52 | CD52 molecule | -0.0067261 |
| MYO5C | myosin VC | -0.00672562 |
| RGS5 | regulator of G-protein signaling 5 | -0.00671709 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00671691 |
| GPC4 | glypican 4 | -0.00669967 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00668618 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00666347 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00666118 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00664087 |
| PLPBP | pyridoxal phosphate binding protein | -0.00663552 |
| PNMA8A | PNMA family member 8A | -0.00663505 |
| LTA4H | leukotriene A4 hydrolase | -0.00662546 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00662444 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00662413 |
| GPR183 | G protein-coupled receptor 183 | -0.00661612 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.00661451 |
| GSPT2 | G1 to S phase transition 2 | -0.00659771 |
| ASRGL1 | asparaginase like 1 | -0.00658356 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00655915 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | -0.00655506 |
| PRKCH | protein kinase C, eta | -0.006542 |
| KIF5C | kinesin family member 5C | -0.00653731 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00652893 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00652424 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00652108 |
| MT1X | metallothionein 1X | -0.00651959 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00651543 |
| AZIN1 | antizyme inhibitor 1 | -0.00651506 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00650708 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00650114 |
| ADI1 | acireductone dioxygenase 1 | -0.00649592 |
| CTSK | cathepsin K | -0.00648689 |
| PCTP | phosphatidylcholine transfer protein | -0.00646778 |
| QKI | QKI, KH domain containing, RNA binding | -0.00642294 |
| TMC5 | transmembrane channel-like 5 | -0.00641788 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00640985 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00640534 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00640378 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00640251 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | -0.00640083 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | -0.00639049 |
| ANXA11 | annexin A11 | -0.00637916 |
| CD86 | CD86 molecule | -0.00636908 |
| HHEX | hematopoietically expressed homeobox | -0.00635447 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.0063469 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | -0.00633978 |
| EREG | epiregulin | -0.00633421 |
| DLD | dihydrolipoamide dehydrogenase | -0.00632088 |
| WDR7 | WD repeat domain 7 | -0.00631799 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00631756 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00631115 |
| SHTN1 | shootin 1 | -0.00629119 |
| RNFT2 | ring finger protein, transmembrane 2 | -0.00628774 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00627337 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00626971 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -0.00625723 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00623114 |
| TMEM254 | transmembrane protein 254 | -0.00618576 |
| ATG5 | autophagy related 5 | -0.00617901 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00617457 |
| APOD | apolipoprotein D | -0.00617223 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00616422 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00616364 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00615807 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00614696 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00611825 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00611405 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00611276 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00610178 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.0060985 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00609435 |
| RRAGA | Ras-related GTP binding A | -0.00608885 |
| DNTT | DNA nucleotidylexotransferase | -0.00607629 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00606613 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00604727 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | -0.00604232 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00604178 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00603094 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00602003 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00600955 |
| HOMER2 | homer scaffolding protein 2 | -0.00600623 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.00599013 |
| ABLIM1 | actin binding LIM protein 1 | -0.00598567 |
| FAM107A | family with sequence similarity 107, member A | -0.00597752 |
| MMP8 | matrix metallopeptidase 8 | -0.00596311 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.0059579 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00595365 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00595332 |
| CLDN10 | claudin 10 | -0.00595022 |
| HAL | histidine ammonia-lyase | -0.00593899 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00592981 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00592237 |
| FECH | ferrochelatase | -0.00591162 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | -0.00590906 |
| FA2H | fatty acid 2-hydroxylase | -0.00589809 |
| CHRDL1 | chordin-like 1 | -0.00588377 |
| TSPAN31 | tetraspanin 31 | -0.00588025 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.00587562 |
| KLK3 | kallikrein-related peptidase 3 | -0.00587339 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00587125 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00586549 |
| CCDC91 | coiled-coil domain containing 91 | -0.00586279 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -0.00585358 |
| MMP7 | matrix metallopeptidase 7 | -0.00585328 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00585247 |
| PRKCQ | protein kinase C, theta | -0.00585067 |
| CLC | Charcot-Leyden crystal galectin | -0.00584685 |
| COG5 | component of oligomeric golgi complex 5 | -0.00584681 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00584618 |
| TSPAN6 | tetraspanin 6 | -0.00583948 |
| PLBD1 | phospholipase B domain containing 1 | -0.00583588 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00582415 |
| STK38L | serine/threonine kinase 38 like | -0.00582301 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00582028 |
| HAT1 | histone acetyltransferase 1 | -0.00581765 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00581342 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | -0.00580944 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00580663 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00580302 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.0057942 |
| TGFA | transforming growth factor, alpha | -0.00579264 |
