DMPK Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description dystrophia myotonica-protein kinase|The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1760)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_DMPK
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Genes

176 co-expressed genes for DMPK from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAMTSL3 ADAMTS-like 3
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AMOT angiomotin
AOC4P amine oxidase, copper containing 4, pseudogene
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AQP7 aquaporin 7
ATF2 activating transcription factor 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN3 ataxin 3
BARX2 BARX homeobox 2
BIRC5 baculoviral IAP repeat containing 5
BRD4 bromodomain containing 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRWD1 bromodomain and WD repeat domain containing 1
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CADM4 cell adhesion molecule 4
CALN1 calneuron 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMTA1 calmodulin binding transcription activator 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC73 cell division cycle 73
CDYL chromodomain protein, Y-like
CEP162 centrosomal protein 162kDa
CFH complement factor H
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLCN3 chloride channel, voltage-sensitive 3
COL14A1 collagen, type XIV, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPB2 carboxypeptidase B2 (plasma)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRHR1 corticotropin releasing hormone receptor 1
CTSB cathepsin B
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DKFZP434C153 DKFZP434C153 protein
DMD dystrophin
DMPK dystrophia myotonica-protein kinase
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DRD1 dopamine receptor D1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELOVL6 ELOVL fatty acid elongase 6
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB2 EPH receptor B2
EXOC4 exocyst complex component 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM153B family with sequence similarity 153, member B
FBXL4 F-box and leucine-rich repeat protein 4
FGF18 fibroblast growth factor 18
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FSHR follicle stimulating hormone receptor
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD5 frizzled class receptor 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCA grancalcin, EF-hand calcium binding protein
GCM1 glial cells missing homolog 1 (Drosophila)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GLRA3 glycine receptor, alpha 3
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR171 G protein-coupled receptor 171
GPR19 G protein-coupled receptor 19
GUCY2F guanylate cyclase 2F, retinal
HCG8 HLA complex group 8
HCRTR2 hypocretin (orexin) receptor 2
HEPH hephaestin
HNF1A HNF1 homeobox A
HOXB7 homeobox B7
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IL13RA1 interleukin 13 receptor, alpha 1
IPO9 importin 9
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JADE3 jade family PHD finger 3
JRKL JRK-like
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRT2 keratin 2, type II
KRT34 keratin 34, type I
LDB3 LIM domain binding 3
LGI1 leucine-rich, glioma inactivated 1
LOR loricrin
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP4 low density lipoprotein receptor-related protein 4
MAGEA8 melanoma antigen family A8
MAGEA9 melanoma antigen family A9
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP2 microtubule-associated protein 2
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN1 mitofusin 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MSH3 mutS homolog 3
NEB nebulin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NHEJ1 nonhomologous end-joining factor 1
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTNG2 netrin G2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX6 paired box 6
PCDH7 protocadherin 7
PCM1 pericentriolar material 1
PGM3 phosphoglucomutase 3
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2B paired-like homeobox 2b
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRKCA protein kinase C, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD51D RAD51 paralog D
RB1CC1 RB1-inducible coiled-coil 1
RBMXL1 RNA binding motif protein, X-linked-like 1
RORB RAR-related orphan receptor B
RREB1 ras responsive element binding protein 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
RXRG retinoid X receptor, gamma
RYR3 ryanodine receptor 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SIX6 SIX homeobox 6
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPA17 sperm autoantigenic protein 17
SPRR2C small proline-rich protein 2C (pseudogene)
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAG1 stromal antigen 1
SULT4A1 sulfotransferase family 4A, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SURF2 surfeit 2
T T, brachyury homolog (mouse)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM184B transmembrane protein 184B
TNK1 tyrosine kinase, non-receptor, 1
TRIO trio Rho guanine nucleotide exchange factor
TSSK2 testis-specific serine kinase 2
UBE4B ubiquitination factor E4B
USP46 ubiquitin specific peptidase 46
WBP4 WW domain binding protein 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBTB14 zinc finger and BTB domain containing 14
ZBTB40 zinc finger and BTB domain containing 40
ZNF132 zinc finger protein 132
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF157 zinc finger protein 157
ZNF202 zinc finger protein 202
ZNF33B zinc finger protein 33B
ZSCAN26 zinc finger and SCAN domain containing 26